concox 800mg tablet - Ethambutol (800mg) medicine

concox 800mg tablet - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Concept Pharmaceuticals Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 27, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 27, 2026

What is concox 800mg tablet used for?

Actol 800mg Tablet (Ethambutol) is used to treat ANTI INFECTIVES. It contains Ethambutol (800mg), which Inhibits arabinosyl transferase (emb) involved in cell wall synthesis of mycobac. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Ethambutol
  • Manufacturer: Concept Pharmaceuticals Ltd
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š concox 800mg tablet Uses & Benefits

Treatment of tuberculosis (in combination with other antitubercular agents); atypical mycobacterial infections.

Off-label uses: Treatment of Mycobacterium avium complex (MAC) infection; prophylaxis in HIV patients.

๐Ÿ“‹ Drug Information

Generic Name(s)Ethambutol
Brand NameActol 800mg Tablet
ManufacturerConcept Pharmaceuticals Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassMycobacterial cell wall inhibitors-Ethambutol
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC); protect from moisture and light.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed from the gastrointestinal tract; peak plasma concentrations occur within 2-4 hours.
DistributionDistributed widely in body tissues and fluids; achieves high concentrations in erythrocytes and kidneys.
Protein Binding20-30%
MetabolismPartially metabolized in the liver to inactive metabolites (aldehyde and dicarboxylic acid derivatives).
Half-Life3-4 hours (can be prolonged in renal impairment)
ExcretionPrimarily excreted unchanged in urine (50-80%) via glomerular filtration and tubular secretion; also excreted in feces.
BioavailabilityApproximately 80%
Onset of ActionWithin 24 hours
Peak Plasma Time2-4 hours
Duration of ActionUp to 24 hours

How It Works

Inhibits arabinosyl transferase (emb) involved in cell wall synthesis of mycobacteria, leading to inhibition of cell wall formation.

Mechanism Steps

1Ethambutol enters mycobacterial cells via passive diffusion.
2It inhibits arabinosyl transferase (emb), an enzyme involved in polymerization of arabinogalactan.
3This disrupts cell wall synthesis by preventing formation of arabinogalactan-mycolic acid complex.

๐Ÿ’ก How to Take concox 800mg tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of concox 800mg tablet

โœ… Common Side Effects

  • Nausea
  • Vomiting
  • Abdominal pain
  • Headache
  • Dizziness
  • Rash

๐Ÿšจ Serious Side Effects

  • Optic neuritis (decreased visual acuity, color blindness)
  • Peripheral neuropathy
  • Hepatotoxicity
  • Thrombocytopenia

โš ๏ธ Rare Side Effects

  • Anaphylaxis
  • Stevens-Johnson syndrome
  • Lactic acidosis
  • Renal failure

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Aluminum hydroxide Major Decreased absorption of ethambutol
Isoniazid Major Increased risk of peripheral neuropathy
Rifampin Major Increased hepatotoxicity risk
Ethionamide Moderate Additive optic neuropathy risk
Pyrazinamide Moderate Increased hepatotoxicity risk
Probenecid Minor Decreased renal excretion of ethambutol

๐Ÿšจ Major Interactions

  • Aluminum hydroxide
  • Isoniazid
  • Rifampin

โšก Moderate Interactions

  • Ethionamide
  • Pyrazinamide

โ„น๏ธ Minor Interactions

  • Probenecid

๐Ÿฝ๏ธ Food Interactions

Food may decrease absorption; take on an empty stomach if possible.

๐Ÿท Alcohol Interaction

Avoid alcohol; may increase hepatotoxicity risk.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to ethambutol; optic neuritis; severe renal impairment (CrCl <10 mL/min).

๐Ÿ“Š Monitoring Parameters

Visual acuity and color vision tests (baseline and monthly); renal function; liver function tests; serum uric acid.

๐Ÿคฑ Lactation Safety

Excreted in breast milk; caution advised.

๐Ÿ’Š Overdose Management

Induce vomiting or gastric lavage; supportive care; monitor for optic toxicity and renal function.

โฐ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose. Do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 27, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for concox 800mg tablet

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Alternative brands with exact same active ingredient (Ethambutol (800mg)):

Medical Note: Always consult your doctor before switching medications.

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