comyetin 500mg capsule
What is comyetin 500mg capsule used for?
Andrecin Eye Drop (Chloramphenicol) is used to treat OTOLOGICALS. It contains Chloramphenicol (500mg), which Inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, pr. Always consult your doctor before use. Take as prescribed.
- Generic Name: Chloramphenicol
- Manufacturer: Modern Laboratories
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ comyetin 500mg capsule Uses & Benefits
Treatment of bacterial conjunctivitis, keratitis, and other superficial ocular infections.
Off-label uses: Prophylaxis in ocular surgery; treatment of blepharitis.
๐ Drug Information
| Generic Name(s) | Chloramphenicol |
| Brand Name | Andrecin Eye Drop |
| Manufacturer | Modern Laboratories |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | OTOLOGICALS |
| Action Class | Chloramphenicol |
| Route of Administration | Topical ophthalmic (eye drops). |
| Storage | Store at 15-30ยฐC (59-86ยฐF); protect from light; keep bottle tightly closed. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, preventing peptide bond formation.
Mechanism Steps
๐ก How to Take comyetin 500mg capsule
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of comyetin 500mg capsule
โ Common Side Effects
- Transient stinging or burning
- Blurred vision
- Eye irritation
- Redness
๐จ Serious Side Effects
- Bone marrow suppression (aplastic anemia)
- Gray baby syndrome (systemic use in neonates)
- Hypersensitivity reactions
โ ๏ธ Rare Side Effects
- Optic neuritis
- Peripheral neuropathy
- Superinfection with resistant organisms
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk due to inhibition of warfarin metabolism. |
| Phenytoin | Major | Increased phenytoin levels and toxicity. |
| Phenobarbital | Major | Decreased chloramphenicol levels. |
| Rifampin | Major | Decreased chloramphenicol efficacy. |
| Oral contraceptives | Moderate | Reduced contraceptive efficacy. |
| Cyclosporine | Moderate | Increased cyclosporine levels. |
| Tacrolimus | Moderate | Increased tacrolimus levels. |
| Acetaminophen | Minor | Possible additive hepatotoxicity. |
| Cimetidine | Minor | Increased chloramphenicol levels. |
๐จ Major Interactions
- Warfarin
- Phenytoin
- Phenobarbital
- Rifampin
โก Moderate Interactions
- Oral contraceptives
- Cyclosporine
- Tacrolimus
โน๏ธ Minor Interactions
- Acetaminophen
- Cimetidine
๐ฝ๏ธ Food Interactions
No significant food interactions reported.
๐ท Alcohol Interaction
Avoid alcohol; may increase risk of hepatotoxicity.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to chloramphenicol; history of bone marrow depression; systemic use in neonates and pregnancy (third trimester).
๐ Monitoring Parameters
Monitor for signs of hypersensitivity, bone marrow suppression (rare with topical use), and superinfection.
๐คฑ Lactation Safety
Caution; small amounts excreted in breast milk, but topical use unlikely to cause significant exposu
๐ Overdose Management
Topical overdose unlikely; if ingested, induce vomiting or gastric lavage; monitor for bone marrow suppression.
โฐ Missed Dose
Apply as soon as remembered; if near next dose, skip missed dose; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for comyetin 500mg capsule
View AllAlternative brands with exact same active ingredient (Chloramphenicol (500mg)):
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entechlor 500mg capsuleSuzikem Drugs Pvt Ltd โน35.16 0.5% COSTLIER
Medical Note: Always consult your doctor before switching medications.
โญ User Reviews
Good quality medicine. Satisfied with the outcome.
Good quality medicine. Satisfied with the outcome.
Found this to be a helpful product. Good results.
Found this to be a helpful product. Good results.
Helpful and effective medicine as per my experience. Always consult a doctor.