Anglocet Plus Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Sudden severe headache, confusion, or difficulty speaking.
- Chest pain, palpitations, or shortness of breath.
- Weakness or numbness on one side of the body.
- Yellowing of the skin or eyes, dark urine, or severe abdominal pain.
- Swelling of the face, lips, or throat, or difficulty breathing.
- Blood in vomit or stool, or unusual bruising or bleeding.
- Very high blood pressure readings or nosebleeds that will not stop.
If experiencing severe symptoms, call emergency services immediately.
What is colo tablet used for?
This medicine is a combination of paracetamol and phenylpropanolamine used for short-term relief of nasal congestion, mild pain, and fever due to colds or allergies. It works by reducing pain and fever and by narrowing nasal blood vessels. It is not recommended for people with high blood pressure, heart disease, or a history of stroke, and it should be used only under medical supervision.
- Generic Name: Paracetamol + Phenylpropanolamine
- Manufacturer: Syncom Formulations I Limited
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 colo tablet के बारे में (Hindi Summary)
उपयोग: यह दवा पैरासिटामोल और फेनिलप्रोपेनॉलामाइन का संयोजन है, जिसका उपयोग सर्दी-जुकाम और एलर्जी के कारण होने वाली नाक बंद, हल्के दर्द और बुखार में राहत के लिए किया जाता है। पैरासिटामोल दर्द और बुखार को कम करता है, जबकि फेनिलप्रोपेनॉलामाइन नाक की रक्त वाहिकाओं को सिकोड़कर जमाव को कम करता है। यह दवा केवल लक्षणों से राहत देती है, बीमारी का इलाज नहीं करती। उच्च रक्तचाप, हृदय रोग, थायरॉइड की समस्या, ग्लूकोमा या स्ट्रोक के इतिहास वाले लोगों को यह दवा नहीं लेनी चाहिए। इसका उपयोग डॉक्टर की सलाह के बिना लंबे समय तक न करें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में जी मिचलाना, पेट में असहजता, मुँह सूखना, घबराहट, बेचैनी, हल्का चक्कर आना और नींद न आना शामिल हैं। कभी-कभी रक्तचाप बढ़ना, दिल की धड़कन तेज होना, तेज सिरदर्द, बेचैनी या पेशाब में कठिनाई जैसी गंभीर समस्याएँ हो सकती हैं। दुर्लभ मामलों में त्वचा पर गंभीर प्रतिक्रिया, खून की बीमारी या लीवर को नुकसान हो सकता है। अगर सीने में दर्द, साँस लेने में तकलीफ, चेहरे या गले में सूजन, या शरीर के किसी हिस्से में अचानक कमजोरी महसूस हो, तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें और मात्रा या अवधि न बढ़ाएँ। इसमें पैरासिटामोल है, इसलिए अन्य दवाओं में पैरासिटामोल की मात्रा जाँच लें ताकि ओवरडोज़ न हो। शराब न पिएँ, क्योंकि इससे लीवर को नुकसान और पेट की परेशानी बढ़ सकती है। अगर आपको उच्च रक्तचाप, दिल की बीमारी, थायरॉइड, ग्लूकोमा या स्ट्रोक की समस्या है, तो यह दवा बिना डॉक्टर की सलाह के न लें। इस दवा से चक्कर या नींद आ सकती है, इसलिए वाहन चलाने या मशीन चलाने से बचें। लक्षण ठीक न हों या बिगड़ें तो डॉक्टर से संपर्क करें।
💊 colo tablet Uses & Benefits
[{"condition":"Common cold with nasal congestion and mild pain or fever","description":"This medicine provides short-term relief of nasal stuffiness together with reduction of mild aches and fever associated with the common cold.","evidence":"Established for short-term symptomatic relief, but phenylpropanolamine-containing products are restricted in many countries."},{"condition":"Allergic rhinitis with nasal congestion","description":"The decongestant component helps shrink swollen nasal passages, while paracetamol addresses any accompanying headache or discomfort.","evidence":"Symptomatic use supported, though safer decongestants are usually preferred."},{"condition":"Sinusitis-related congestion and pain","description":"Used for temporary relief of sinus pressure, nasal blockage, and mild sinus headache.","evidence":"Limited to short-term symptom relief; not a treatment for infection."},{"condition":"Influenza-like illness with body ache and blocked nose","description":"May ease muscle aches and fever while reducing nasal congestion during viral upper respiratory infections.","evidence":"Symptomatic use only; no antiviral effect."}]
Off-label uses: [{"condition":"Weight loss","description":"Phenylpropanolamine was historically used as an appetite suppressant, but this is no longer recommended due to safety concerns.","evidence":"Not recommended; associated with serious cardiovascular and stroke risk."},{"condition":"Urinary stress incontinence","description":"Phenylpropanolamine has been studied for short-term management of stress incontinence in some women, but this is not a standard use.","evidence":"Limited and not recommended for routine practice."}]
Primary treatment for: Common cold and allergic rhinitis with nasal congestion and mild pain or fever
Also treats: Sinusitis, Influenza-like illness, Upper respiratory tract infection
📋 Drug Information
| Generic Name(s) | Paracetamol + Phenylpropanolamine |
| Brand Name | Anglocet Plus Tablet |
| Manufacturer | Syncom Formulations I Limited |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Analgesic, Antipyretic, Decongestant |
| Route of Administration | Oral. This medicine is taken by mouth as an immediate-release tablet, usually with water and food to reduce stomach upset |
| Storage | Store at room temperature between 15°C and 30°C in a dry place, away from direct sunlight and moisture. Keep the tablets in their original container or blister pack, tightly closed. Do not refrigerate unless the label specifically says so. Keep out of the reach of children and pets. |
| Shelf Life | Not established from the available information. Refer to the expiry date printed on the pack. Do not use after the expiry date. |
| WHO Guideline | Not established from the available information. The World Health Organization does not recommend phenylpropanolamine-containing products for routine use because of safety concerns. |
| ICMR Guideline | Not established from the available information. The Indian Council of Medical Research has not issued a specific recommendation for this fixed-dose combination. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with different mechanisms. Paracetamol reduces pain and fever mainly by acting on the central nervous system, where it inhibits prostaglandin synthesis and modulates pain pathways and the hypothalamic temperature set-point. Phenylpropanolamine is a sympathomimetic amine that directly and indirectly stimulates alpha-adrenergic receptors, causing constriction of blood vessels in the nasal mucosa, which reduces swelling and congestion. The combination addresses both the discomfort and the nasal blockage of upper respiratory conditions.
Mechanism Steps
💡 How to Take colo tablet
Strength: Immediate-release tablet for oral use. The exact strength of paracetamol and phenylpropanolamine in this product is not established from the available information. Refer to the product label or ask your pharmacist.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken by mouth every 4 to 6 hours as needed for symptoms, but the exact dose and frequency must be individualized by a qualified clinician based on your age, weight, medical conditions, other medicines, and the severity of your symptoms. Do not exceed the maximum daily dose stated on the label or prescribed by your doctor. Because this product contains paracetamol, the total daily paracetamol intake from all sources should not exceed 4 grams in most adults, and lower limits apply to people with liver disease, alcohol use, or low body weight. Phenylpropanolamine should be used at the lowest effective dose for the shortest possible time. Do not use this medicine for more than a few days without consulting a doctor. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. This combination is generally not recommended for children because of the risks associated with phenylpropanolamine. |
| Elderly Dosage | Elderly patients may be more sensitive to the cardiovascular and central nervous system effects of phenylpropanolamine, including increased blood pressure, dizziness, and confusion. Use with caution and at the lowest effective dose. A qualified clinician should individualize the dose based on kidney and liver function, other medical conditions, and concurrent medicines. |
| Renal Impairment | Dose adjustment may be needed in people with kidney disease because paracetamol metabolites and phenylpropanolamine are excreted by the kidneys. The exact adjustment must be individualized by a qualified clinician based on the degree of kidney impairment. Use with caution and monitor for side effects. |
| Hepatic Impairment | Use with caution in people with liver disease. The paracetamol component can worsen liver injury, and the maximum daily dose may need to be reduced. A qualified clinician should determine the appropriate dose and duration based on liver function tests and clinical status. Avoid alcohol completely. |
| Maximum Daily Dose | The maximum daily dose must be individualized by a qualified clinician. For paracetamol, the usual adult maximum is 4 grams per day from all sources, but lower limits apply in liver disease, alcohol use, or low body weight. The maximum daily dose of phenylpropanolamine in this combination is not established from the available information. Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of colo tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| MAOIs | Major | |
| Other decongestants | Major | |
| Warfarin | Major | |
| Beta-blockers | Moderate | |
| Tricyclic antidepressants | Moderate | |
| Digoxin | Moderate | |
| Ergot alkaloids | Moderate | |
| Antihypertensives | Moderate | |
| Caffeine | Minor | |
| Antacids | Minor |
🚨 Major Interactions
- Monoamine oxidase inhibitors (MAOIs)
- Other sympathomimetic decongestants
- Warfarin
- Alcohol
⚡ Moderate Interactions
- Beta-blockers
- Tricyclic antidepressants
- Digoxin
- Ergot alkaloids
- Antihypertensive medicines
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. It increases the risk of paracetamol-related liver damage and can worsen stomach irritation. Alcohol may also add to the cardiovascular stimulant effects of phenylpropanolamine, raising the risk of high blood pressure and heart rhythm problems.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Uncontrolled high blood pressure.","Severe coronary artery disease or recent heart attack.","History of hemorrhagic stroke.","Hyperthyroidism.","Closed-angle glaucoma.","Use of monoamine oxidase inhibitors within the past 14 days.","Known hypersensitivity to paracetamol, phenylpropanolamine, or any component of the product.","Severe liver disease or active liver failure."]
⚠️ Warnings & Precautions
["This medicine contains phenylpropanolamine, which has been associated with an increased risk of hemorrhagic stroke; use only if specifically approved by your doctor.","Do not exceed the recommended dose of paracetamol; accidental overdose can cause serious liver damage.","Avoid alcohol while taking this medicine.","Use with caution in people with diabetes, thyroid disease, heart disease, or prostate enlargement.","May cause dizziness or drowsiness; avoid driving or operating machinery until you know how it affects you.","Do not use for more than a few days without medical advice.","Check other medicines for paracetamol content to avoid doubling the dose.","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding."]
🤱 Lactation Safety
Not established from the available information. Paracetamol passes into breast milk in small amounts and is generally considered compatible with breastfeeding, but phenylpropanolamine may reduce milk production and is not preferred during lactation. Consult your doctor before use while breastfeeding.
💊 Overdose Management
Overdose of this medicine can be dangerous, mainly because of paracetamol-induced liver injury and phenylpropanolamine-induced cardiovascular effects. Symptoms of paracetamol overdose may include nausea, vomiting, abdominal pain, and later signs of liver failure such as yellowing of the skin or eyes and confusion. Phenylpropanolamine overdose can cause severe high blood pressure, fast or irregular heartbeat, agitation, and seizures. If you suspect an overdose, seek emergency medical care immediately. Do not wait for symptoms to appear. Treatment may include activated charcoal, acetylcysteine for paracetamol toxicity, and supportive care for cardiovascular effects. Bring the medicine container to the hospital.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose. If it is nearly time for the next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. If you are unsure, contact your doctor or pharmacist.
Additional Safety Advice
Take this medicine exactly as directed by your doctor and do not exceed the recommended dose or duration. Because it contains paracetamol, check all other medicines you use for paracetamol or acetaminophen to avoid accidental overdose, which can seriously damage the liver. Avoid alcohol while taking this medicine, as it increases the risk of liver injury and stomach bleeding. Do not use this medicine if you have uncontrolled high blood pressure, severe heart disease, an overactive thyroid, closed-angle glaucoma, or a history of stroke, unless a specialist has specifically approved it. Phenylpropanolamine can raise blood pressure and heart rate, so monitor your blood pressure if you have any cardiovascular risk factors. Do not drive or operate heavy machinery until you know how this medicine affects you, because it can cause dizziness or drowsiness. Tell your doctor about all prescription, over-the-counter, and herbal products you take, especially monoamine oxidase inhibitors, blood pressure medicines, and other decongestants. Stop this medicine and seek medical advice if symptoms persist beyond a few days, worsen, or are accompanied by fever, rash, or breathing difficulty. Keep this medicine out of the reach of children and store it in its original packaging.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the cardiovascular and central nervous system effects of phenylpropanolamine, including increased blood pressure, dizziness, confusion, and difficulty urinating. They are also more likely to have heart disease, kidney disease, and other conditions that increase the risk of side effects. Use this medicine with caution, at the lowest effective dose, and only under medical supervision. Monitor blood pressure regularly and report any unusual symptoms to your doctor.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended if you are planning pregnancy, as phenylpropanolamine may pose risks to the mother and fetus. Paracetamol is generally considered acceptable for short-term use during pregnancy when clearly needed, but the combination should be avoided. Consult your doctor or obstetrician to discuss safer alternatives for symptom relief before trying to conceive.
🏥 Post-Surgery Considerations
Not established from the available information. After surgery, many medicines can interact with anesthetics and pain relievers. Inform your surgeon and anesthesiologist about all medicines you take, including this one. Do not take this medicine after surgery without your doctor's approval, especially if you have cardiovascular risk factors.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure. Phenylpropanolamine can interact with local anesthetics containing epinephrine and may increase blood pressure and heart rate. Your dentist may recommend stopping this medicine or using an alternative before the procedure. Paracetamol in this medicine may also interact with other pain relievers used after dental work, so always disclose all medicines.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine can cause dizziness, drowsiness, and a rise in blood pressure. Avoid strenuous exercise or activities that require balance and alertness until you know how the medicine affects you. If you feel dizzy, palpitations, or short of breath during exercise, stop immediately and seek medical advice.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, drowsiness, nervousness, or insomnia, which can affect your ability to work, drive, or operate machinery. Avoid driving or operating heavy equipment until you know how it affects you. If your job requires alertness, discuss alternative treatments with your doctor. The need for frequent dosing may also interfere with work schedules, so plan your doses around your daily routine.
🛑 When to Stop This Medicine
Stop taking this medicine and seek medical advice if your symptoms do not improve within a few days, if they worsen, or if you develop any serious side effects such as severe headache, chest pain, palpitations, difficulty breathing, or signs of an allergic reaction. Do not stop any prescribed medicine without consulting your doctor. If you have been using this medicine regularly for a long time, talk to your doctor before stopping, as they may need to adjust your treatment plan.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended. Prolonged use of paracetamol at high doses can lead to liver injury and kidney problems. Phenylpropanolamine can cause persistent high blood pressure, heart rhythm problems, and an increased risk of stroke with continued use. If you need symptom relief for more than a few days, consult your doctor to find a safer alternative and to evaluate the underlying cause of your symptoms.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Using saline sprays or rinses can help relieve nasal congestion without the risks of decongestant medicines.
Evidence: Well-established for symptom relief.Inhaling steam from a bowl of hot water can temporarily ease nasal stuffiness.
Evidence: Commonly used, though evidence is limited.For allergic rhinitis, antihistamines can reduce sneezing, itching, and runny nose, but they may cause drowsiness.
Evidence: Well-established for allergies.These prescription nasal sprays reduce inflammation in the nasal passages and are effective for allergic rhinitis.
Evidence: Well-established for allergic rhinitis.If only pain or fever is present, paracetamol alone avoids the cardiovascular risks of phenylpropanolamine.
Evidence: Well-established for pain and fever.💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Not established from the available information. This medicine does not interact with vaccines, but if you are unwell with a fever, your doctor may advise delaying vaccination until you recover. Follow your doctor's advice regarding vaccination timing.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C.
❌ DON'T
Do not refrigerate unless the label specifically says so.
✅ DO
Keep in the original container or blister pack.
❌ DON'T
Do not transfer to unmarked containers.
✅ DO
Keep away from direct sunlight and moisture.
❌ DON'T
Do not store in the bathroom cabinet.
✅ DO
Keep out of the reach of children and pets.
❌ DON'T
Do not use after the expiry date.
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with the prescription label clearly visible. Bring a copy of your prescription or a letter from your doctor, especially if you are crossing international borders, because phenylpropanolamine is restricted or banned in many countries. Store the tablets in a cool, dry place away from direct sunlight and moisture. If you are changing time zones, continue taking the medicine only as needed for symptoms, and do not exceed the maximum daily dose. Check the customs regulations of your destination before carrying this medicine. If you are flying, keep it in your carry-on luggage with other essential medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Paracetamol usually starts relieving pain and fever within 30 to 60 minutes, and the decongestant effect may begin within 15 to 30 minutes. However, individual response can vary.
A: This medicine is intended for short-term use only, usually for a few days. Do not use it for longer than your doctor recommends because of the risks associated with phenylpropanolamine and paracetamol.
A: Phenylpropanolamine can raise blood pressure and may reduce the effectiveness of blood pressure medicines. Consult your doctor before combining them.
A: Pediatric dosing is not established, and this combination is generally not recommended for children because of the risks of phenylpropanolamine. Consult a pediatrician for safer alternatives.
A: If you remember within half the dosing interval, take the missed dose. If it is almost time for the next dose, skip it and continue with your regular schedule. Do not double dose.
🤔 Common Patient Concerns
🔄 Substitutes for colo tablet
View AllAlternative brands with exact same active ingredient:
-
sneez bye tabletZydus Cadila ₹4.50 70% CHEAPER
-
coldwok tabletWockhardt Ltd ₹5.25 65% CHEAPER
-
cetral cold tabletAlembic Pharmaceuticals Ltd ₹6.25 58.3% CHEAPER
-
mycet cold tabletMorepen Laboratories Ltd ₹6.25 58.3% CHEAPER
-
coldcet p tabletGlenmark Pharmaceuticals Ltd ₹6.47 56.9% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is safe for everyone with a cold.
Fact: It is not safe for people with uncontrolled high blood pressure, heart disease, or a history of stroke because of the phenylpropanolamine component. - Myth: More tablets will relieve congestion faster.
Fact: Taking more than the recommended dose increases the risk of serious side effects, including liver damage and dangerous rises in blood pressure. - Myth: It is okay to take this medicine with other cold remedies.
Fact: Many cold remedies contain paracetamol or decongestants, and combining them can lead to overdose or additive cardiovascular effects. - Myth: This medicine can cure a cold.
Fact: It only relieves symptoms; it does not treat the underlying viral infection.
🔄 Alternative Options
Generic Alternatives
- Paracetamol and phenylpropanolamine combination products from other manufacturers, if available and approved in your region.
Brand Alternatives
- Not established from the available information.