Coliv Syrup: Complete Guide To Uses, Dosage, Side Effects, And Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain or cramping that does not go away
- Signs of dehydration such as dizziness, dry mouth, or reduced urine output
- Swelling of the face, lips, or throat, or difficulty breathing
- Yellowing of the skin or eyes
- Persistent vomiting or inability to keep fluids down
- Irregular heartbeat or palpitations
- Confusion or extreme weakness
If experiencing severe symptoms, call emergency services immediately.
What is coliv syrup used for?
This medicine is a combination syrup of Tricholine Citrate 550 mg and Sorbitol 7.15 gm. It is used as a supportive treatment for fatty liver and to relieve constipation linked to liver and gallbladder problems. Tricholine citrate helps the liver export fat, while sorbitol softens stool by drawing water into the bowel. It should be taken only under a doctor's guidance.
- Generic Name: Tricholine Citrate + Sorbitol
- Manufacturer: Briskon Laboratories
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 coliv syrup के बारे में (Hindi Summary)
उपयोग: यह दवा ट्राइकोलीन सिट्रेट 550 मिलीग्राम और सोर्बिटोल 7.15 ग्राम का मिश्रण है। इसका उपयोग फैटी लिवर में सहायक उपचार के रूप में और लिवर तथा पित्त की थैली से जुड़ी कब्ज को दूर करने के लिए किया जाता है। ट्राइकोलीन सिट्रेट लिवर को वसा बाहर निकालने में मदद करता है, जबकि सोर्बिटोल आंत में पानी खींचकर मल को नरम करता है। यह दवा लिवर रोग का इलाज नहीं है, बल्कि डॉक्टर की सलाह से सहायक चिकित्सा के रूप में ली जाती है।
साइड इफेक्ट्स: इस दवा को लेने पर आमतौर पर पेट में हल्की गड़बड़, गैस, पेट फूलना, और दस्त जैसी शिकायतें हो सकती हैं। कुछ लोगों को जी मिचलाना, उल्टी, पेट में ऐंठन, या सिरदर्द भी हो सकता है। बहुत कम मामलों में गंभीर दस्त, निर्जलीकरण, या एलर्जी की प्रतिक्रिया हो सकती है। अगर दस्त लंबे समय तक बने रहें, चक्कर आएं, पेशाब कम आए, या सांस लेने में तकलीफ हो, तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर द्वारा बताई गई मात्रा और अवधि के अनुसार ही लें। अपने आप मात्रा न बढ़ाएं, क्योंकि इससे गंभीर दस्त और निर्जलीकरण हो सकता है। दिनभर पर्याप्त पानी पिएं। दवा को भोजन के साथ या भोजन के तुरंत बाद लें। अगर आपको मधुमेह है, तो ब्लड शुगर की निगरानी करें। शराब का सेवन पूरी तरह बंद कर दें। गर्भावस्था या स्तनपान के दौरान इस दवा का उपयोग डॉक्टर की सलाह के बिना न करें।
💊 coliv syrup Uses & Benefits
[{"condition":"Non-alcoholic fatty liver disease (supportive care)","description":"This medicine is used as an add-on to diet and lifestyle changes to help the liver mobilise and export fat, which may improve liver function tests over time.","evidence":"Limited to moderate; used mainly as supportive therapy"},{"condition":"Constipation associated with liver or gallbladder disease","description":"The sorbitol component softens stool and promotes bowel movement, which helps patients who develop constipation due to poor bile flow or liver-related sluggish digestion.","evidence":"Well-established for the laxative component"},{"condition":"Indigestion and flatulence with liver dysfunction","description":"This medicine is sometimes prescribed to relieve bloating, heaviness, and poor digestion in people with mild liver complaints.","evidence":"Limited; based on clinical practice rather than large trials"},{"condition":"Cholestatic liver conditions (supportive)","description":"Tricholine citrate may support bile flow and fat digestion in some cholestatic conditions, but it is not a primary treatment for any specific liver disease.","evidence":"Limited"}]
Off-label uses: [{"condition":"Hyperlipidaemia (supportive)","description":"Sometimes used off-label as a supportive agent in patients with high cholesterol and fatty liver, but it is not a standard lipid-lowering medicine.","evidence":"Limited"},{"condition":"General detoxification or wellness","description":"Some people use this medicine off-label as a liver tonic, but there is no strong clinical evidence to support this practice.","evidence":"Insufficient"}]
Primary treatment for: Non-alcoholic fatty liver disease and associated constipation
Also treats: Constipation, Indigestion with flatulence, Mild cholestatic liver conditions
📋 Drug Information
| Generic Name(s) | Tricholine Citrate + Sorbitol |
| Brand Name | Al Live Syrup |
| Manufacturer | Briskon Laboratories |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | VITAMINS MINERALS NUTRIENTS |
| Action Class | Lipotropic Agent |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C in a dry place. Keep the bottle tightly closed and protect it from direct sunlight. Do not freeze the syrup. |
| Shelf Life | 24 months from the date of manufacture, or as printed on the pack. Use within the recommended period after opening the bottle, as advised on the label. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works through two complementary mechanisms. Tricholine citrate is a choline salt that provides choline, which the liver uses to make phosphatidylcholine and very-low-density lipoprotein. These molecules help package triglycerides and move them out of liver cells, reducing fat accumulation. Sorbitol is a non-absorbable sugar alcohol that acts as an osmotic laxative. It draws water into the large intestine, increases stool water content, and stimulates bowel movement. Together, these actions support liver fat handling and relieve constipation, which often coexist in people with liver and gallbladder problems.
Mechanism Steps
💡 How to Take coliv syrup
Strength: Each dose of this syrup contains Tricholine Citrate 550 mg and Sorbitol 7.15 gm.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one to two teaspoonfuls (5 to 10 mL) taken once or twice daily, depending on the condition being treated and the doctor's assessment. Some doctors advise taking it at bedtime for constipation, while others recommend it after meals for liver support. The exact dose and duration must be individualized by a qualified clinician based on the indication, age, weight, kidney function, liver function, and response to treatment. Do not change the dose on your own. If you have diabetes or kidney disease, your doctor may adjust the dose or recommend a different medicine. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician for an appropriate dose based on your child's age, weight, and condition. |
| Elderly Dosage | Older adults may be more sensitive to the laxative effect of sorbitol and are at higher risk of dehydration and electrolyte imbalance. The dose should be individualized by a qualified clinician, and hydration status should be monitored closely. Elderly patients on diuretics or with kidney disease need extra caution. |
| Renal Impairment | This medicine should be used with caution in people with kidney disease. Severe diarrhoea can worsen kidney function by causing dehydration. The dose must be individualized by a qualified clinician, and kidney function and hydration should be monitored. In severe kidney disease with reduced urine output, this medicine is usually avoided. |
| Hepatic Impairment | No specific dose adjustment is established for people with liver disease. However, because this medicine is often used in patients with liver problems, the dose should be individualized by a qualified clinician based on the severity of liver disease and the overall clinical picture. Regular monitoring of liver function tests is advised. |
| Maximum Daily Dose | The maximum daily dose is not established from the available information. Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of coliv syrup
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Furosemide | Major | |
| Hydrochlorothiazide | Major | |
| Other laxatives | Major | |
| Metformin | Moderate | |
| Insulin | Moderate | |
| Digoxin | Moderate | |
| Lithium | Moderate | |
| Oral iron | Minor | |
| Magnesium antacids | Minor | |
| Warfarin | Minor |
🚨 Major Interactions
- Diuretics (e.g., furosemide, hydrochlorothiazide)
- Other laxatives
⚡ Moderate Interactions
- Antidiabetic medicines (e.g., metformin, insulin)
- Digoxin
- Lithium
🍷 Alcohol Interaction
Alcohol should be avoided completely while taking this medicine. Alcohol puts extra stress on the liver, which works against the purpose of tricholine citrate. It can also worsen stomach irritation and increase the risk of dehydration from the laxative effect of sorbitol. If you drink alcohol regularly, discuss this with your doctor before starting this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to tricholine citrate, sorbitol, or any other ingredient in this medicine","Intestinal obstruction or suspected bowel blockage","Severe dehydration or electrolyte imbalance","Galactosaemia or hereditary fructose intolerance","Severe kidney disease with reduced urine output","Uncontrolled diabetes without medical supervision","Children below the age recommended by a paediatrician"]
⚠️ Warnings & Precautions
["Do not exceed the dose recommended by your doctor, as higher doses can cause severe diarrhoea.","Drink plenty of water to prevent dehydration while taking this medicine.","Use with caution if you have diabetes, as sorbitol can affect blood sugar levels.","Avoid alcohol completely during treatment.","Do not take other laxatives at the same time unless your doctor advises it.","Inform your doctor if you have kidney disease, heart disease, or are on diuretics.","Stop the medicine and seek medical help if you develop severe abdominal pain, vomiting, or blood in stool.","Keep out of reach of children.","Do not use after the expiry date."]
🤱 Lactation Safety
It is not known whether tricholine citrate or sorbitol passes into breast milk in amounts that could affect a breastfed baby. This medicine should be used during breastfeeding only if a qualified clinician advises it. Monitor the baby for loose stools or unusual irritability and inform your doctor if you notice any change.
💊 Overdose Management
Taking more than the recommended dose can cause severe diarrhoea, abdominal cramps, dehydration, and electrolyte imbalance. If you suspect an overdose, stop the medicine immediately and drink plenty of fluids if you are able to. Seek medical attention without delay, especially if you have dizziness, reduced urine output, muscle weakness, or palpitations. Carry the medicine pack with you so that the treating doctor knows exactly what was taken.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember, provided there is still a long time before your next dose. If it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. If you miss doses often, speak to your doctor about adjusting your routine.
Additional Safety Advice
Take this medicine exactly in the dose and for the duration advised by your doctor. Do not increase the dose on your own to get faster results, because a higher dose can cause severe diarrhoea and dehydration. Drink plenty of water throughout the day while using this medicine, since sorbitol works by pulling water into the bowel. Take this medicine with or just after food to reduce stomach upset. If you have diabetes, check your blood sugar more often because sorbitol can affect glucose levels. Do not drive or operate heavy machinery if you feel dizzy or weak from loose motions. Tell your doctor about all other medicines, especially diuretics, blood pressure medicines, and diabetes medicines, before starting this product. Avoid alcohol completely while taking this medicine, as alcohol can worsen liver stress and increase the risk of stomach upset. Keep this medicine out of the reach of children. Do not use it after the expiry date printed on the pack. If you are pregnant, planning pregnancy, or breastfeeding, use this medicine only if your doctor clearly advises it.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Older adults are more prone to dehydration and electrolyte imbalance from the laxative effect of sorbitol. Use the lowest effective dose and monitor hydration and kidney function. Elderly patients on diuretics or with heart or kidney disease need extra caution. Report any dizziness, weakness, or reduced urine output to your doctor promptly.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, inform your doctor before starting or continuing this medicine. The safety of this combination during pregnancy is not well established. Your doctor will weigh the benefits and risks and may recommend an alternative treatment if needed.
🏥 Post-Surgery Considerations
After surgery, use this medicine only if your surgeon or doctor advises it. The laxative effect may be helpful for post-operative constipation, but dehydration can slow recovery. Monitor fluid intake and report any unusual symptoms to your healthcare team.
🦷 Dental Procedures
There are no specific restrictions for dental procedures while taking this medicine. However, inform your dentist about all medicines you take. If you need sedation or surgery, tell the dentist or anesthesiologist about this medicine and any other prescriptions.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is encouraged, but avoid intense workouts if you are feeling weak or dizzy from loose motions. Stay hydrated during exercise. If you have liver disease, discuss an appropriate exercise plan with your doctor before starting a new routine.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause loose stools or dizziness in some people, which can affect your ability to drive or operate heavy machinery. Avoid driving if you feel unwell. Most people can continue their normal work routine, but take extra care if your job involves physical exertion or operating machines. Inform your employer or supervisor if you need to take frequent bathroom breaks.
🛑 When to Stop This Medicine
Stop this medicine and contact your doctor if you develop severe diarrhoea, signs of dehydration, allergic reactions, or any serious side effect. Do not stop a prescribed medicine without consulting your doctor, especially if you are taking it for a chronic liver condition. Your doctor will decide whether to stop, reduce, or change the medicine based on your response and test results.
📅 Long-Term Use Effects
Long-term use of this medicine should be supervised by a doctor. Prolonged use of sorbitol can lead to loose stools, dehydration, and electrolyte imbalance, especially in elderly people and those with kidney disease. Tricholine citrate is generally considered safe for long-term supportive use, but it does not cure liver disease. Regular monitoring of liver function tests, blood sugar, and hydration is advised. If you notice persistent diarrhoea, weakness, or reduced urine output, contact your doctor.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Losing 5-10% of body weight can significantly reduce liver fat and improve liver enzymes.
Evidence: Well-establishedAerobic exercise and resistance training help reduce liver fat and improve overall health.
Evidence: Well-establishedAlternative osmotic laxatives for constipation, especially if sorbitol is not tolerated.
Evidence: Well-establishedSometimes used in non-alcoholic fatty liver disease under medical supervision.
Evidence: Limited to moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you have liver disease, discuss vaccination against hepatitis A and hepatitis B with your doctor, as these infections can worsen liver health.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C
❌ DON'T
Do not refrigerate or freeze the syrup
✅ DO
Keep the bottle tightly closed
❌ DON'T
Do not leave the cap loose
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store near a heat source
✅ DO
Keep out of reach of children
❌ DON'T
Do not transfer to another unmarked container
✈️ Traveling with This Medicine
Carry this medicine in its original bottle with the prescription label intact. Keep a copy of your prescription with you, especially for international travel. Store the bottle in a cool, dry place away from direct sunlight. If you are travelling across time zones, continue your doses at the same interval as prescribed, but do not double up. Drink extra water during travel to prevent dehydration, especially on long flights. Check customs rules for carrying prescription medicines before you travel.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: The laxative effect usually starts within 30 minutes to 6 hours. The supportive effect on liver fat may take several weeks to show any change in liver function tests.
A: It can be taken daily if your doctor prescribes it, but long-term use should be supervised with regular monitoring of liver function, blood sugar, and hydration.
A: Mild loose stools are common. Drink plenty of fluids. If diarrhoea is severe, persistent, or associated with dizziness or reduced urine output, stop the medicine and contact your doctor immediately.
A: It depends on the other medicines. Always inform your doctor about all medicines you take, including supplements, before starting this product.
A: Pediatric dosing is not established from available information. Consult a pediatrician before giving this medicine to a child.
🤔 Common Patient Concerns
🔄 Substitutes for coliv syrup
View AllAlternative brands with exact same active ingredient:
-
roniliv syrupMedihands Pharmaceuticals ₹40.00 16.7% CHEAPER
-
livomed syrupTeblik Drugs Pvt Ltd ₹60.00 25% COSTLIER
-
heptacare syrupMedisurf Pharma ₹120.00 150% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure fatty liver completely.
Fact: This medicine is a supportive treatment. Fatty liver requires diet, exercise, weight loss, and treatment of underlying causes such as diabetes or high cholesterol. - Myth: More syrup means faster liver recovery.
Fact: Taking more than the prescribed dose can cause severe diarrhoea and dehydration. It does not speed up liver recovery. - Myth: This medicine is safe for everyone.
Fact: It is not safe for people with bowel obstruction, severe dehydration, galactosaemia, or fructose intolerance. It should be used with caution in diabetes and kidney disease. - Myth: This medicine can be taken long-term without monitoring.
Fact: Long-term use should be supervised by a doctor with regular monitoring of liver function, blood sugar, and hydration.
🔄 Alternative Options
Generic Alternatives
- Tricholine citrate and sorbitol syrup (generic)
Brand Alternatives
- Coliv Syrup