Biospas 20mg/325mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain that does not improve
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes (jaundice)
- Decreased urine output or inability to urinate
- Fast or irregular heartbeat
- Confusion or hallucinations
If experiencing severe symptoms, call emergency services immediately.
What is coligan 20mg/325mg tablet used for?
This medicine is a combination of dicyclomine and paracetamol used to treat abdominal cramps and pain associated with irritable bowel syndrome and other gastrointestinal spasms. It works by relaxing gut muscles and relieving pain.
- Generic Name: Dicyclomine + Paracetamol
- Manufacturer: Salubry Life Sciences
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 coligan 20mg/325mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा पेट की ऐंठन और दर्द के इलाज के लिए इस्तेमाल की जाती है, खासकर इरिटेबल बाउल सिंड्रोम (IBS) और अन्य गैस्ट्रोइंटेस्टाइनल विकारों में। यह पेट की मांसपेशियों को आराम देकर ऐंठन कम करती है और दर्द से राहत देती है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मुंह सूखना, धुंधली दृष्टि, चक्कर आना, नींद आना, मतली, कब्ज और पेशाब करने में कठिनाई शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, तेज धड़कन, भ्रम या पेट में तेज दर्द हो सकता है। किसी भी गंभीर लक्षण पर तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक से अधिक न लें। धुंधली दृष्टि या नींद आने पर वाहन न चलाएं। शराब का सेवन न करें क्योंकि इससे लीवर को नुकसान और नींद बढ़ सकती है। यदि आपको ग्लूकोमा, मायस्थेनिया ग्रेविस, किडनी या लीवर की बीमारी है तो डॉक्टर को बताएं। बच्चों से दूर रखें।
💊 coligan 20mg/325mg tablet Uses & Benefits
[{"condition":"Irritable bowel syndrome (IBS)","description":"Relieves abdominal cramps and pain associated with IBS by reducing smooth muscle spasms in the gut.","evidence":"Well-established"},{"condition":"Functional bowel disorders","description":"Used to manage abdominal pain and discomfort in functional gastrointestinal disorders.","evidence":"Moderate"},{"condition":"Biliary colic","description":"May help relieve pain from biliary spasms, though not a first-line treatment.","evidence":"Limited"},{"condition":"Renal colic","description":"Sometimes used as an adjunct for pain relief in renal colic, but evidence is limited.","evidence":"Limited"}]
Off-label uses: [{"condition":"Menstrual cramps","description":"Occasionally prescribed off-label to relieve dysmenorrhea due to antispasmodic and analgesic effects.","evidence":"Limited"},{"condition":"Gastroenteritis-related cramps","description":"May be used off-label to reduce abdominal cramping in infectious gastroenteritis, but not routinely recommended.","evidence":"Limited"}]
Primary treatment for: Irritable bowel syndrome (IBS)
Also treats: Functional bowel disorders, Biliary colic, Renal colic, Gastroenteritis-related cramps
📋 Drug Information
| Generic Name(s) | Dicyclomine + Paracetamol |
| Brand Name | Abdospas 20mg/500mg Tablet |
| Manufacturer | Salubry Life Sciences |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Antispasmodic and Analgesic Combination |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Dicyclomine is a synthetic anticholinergic agent that blocks muscarinic acetylcholine receptors on smooth muscle cells in the gastrointestinal tract. By inhibiting acetylcholine binding, it reduces smooth muscle contractility and relieves spasms. Paracetamol acts primarily in the central nervous system by inhibiting prostaglandin synthesis, thereby reducing pain perception and fever. The combination provides both antispasmodic and analgesic effects, targeting abdominal cramps and associated pain.
Mechanism Steps
💡 How to Take coligan 20mg/325mg tablet
Strength: Each tablet contains dicyclomine 20 mg and paracetamol 325 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally two to four times daily, as prescribed by a doctor. The dose may be adjusted based on the severity of symptoms and the patient's response. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the anticholinergic effects of dicyclomine. Use with caution and consider lower doses. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Dicyclomine is excreted by the kidneys; dose adjustment may be necessary in patients with renal impairment. Consult a doctor for individualized dosing. |
| Hepatic Impairment | Paracetamol and dicyclomine are metabolized in the liver. Use with caution in patients with hepatic impairment. Dose reduction may be required. Consult a doctor for individualized dosing. |
| Maximum Daily Dose | The maximum daily dose of paracetamol should not exceed 4000 mg (4 grams) from all sources. For dicyclomine, the maximum recommended daily dose is 160 mg. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of coligan 20mg/325mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Other anticholinergics | Major | |
| Alcohol | Major | |
| Metoclopramide | Moderate | |
| Cholestyramine | Moderate | |
| Antacids | Moderate | |
| Caffeine | Minor |
🚨 Major Interactions
- Other anticholinergic drugs (e.g., atropine, antihistamines, tricyclic antidepressants)
- Warfarin
- Alcohol
⚡ Moderate Interactions
- Metoclopramide
- Cholestyramine
- Antacids
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol increases the risk of liver damage from paracetamol and enhances the sedative effects of dicyclomine, leading to increased drowsiness and impaired coordination.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to dicyclomine, paracetamol, or any component of the formulation","Glaucoma (narrow-angle)","Myasthenia gravis","Obstructive uropathy (e.g., bladder neck obstruction)","Paralytic ileus","Severe hepatic impairment or active liver disease","Severe renal impairment","Breastfeeding (due to potential anticholinergic effects in infants)"]
⚠️ Warnings & Precautions
["Use with caution in elderly patients due to increased risk of anticholinergic effects.","Avoid in patients with known or suspected gastrointestinal obstruction.","Do not exceed the recommended dose of paracetamol; overdose can cause severe liver damage.","May cause drowsiness or blurred vision; avoid driving or operating machinery until effects are known.","Use with caution in patients with autonomic neuropathy, hyperthyroidism, or cardiac disease.","Consult a doctor before use if you have liver or kidney disease.","Do not use for prolonged periods without medical supervision."]
🤱 Lactation Safety
Dicyclomine may pass into breast milk and could cause anticholinergic effects in the infant. Paracetamol is considered safe during breastfeeding. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose of this medicine can be serious, especially due to paracetamol. Symptoms of paracetamol overdose include nausea, vomiting, abdominal pain, and liver damage, which may not appear for 24-48 hours. If overdose is suspected, seek emergency medical attention immediately, even if you feel well. Treatment may include activated charcoal, N-acetylcysteine, and supportive care. Dicyclomine overdose can cause anticholinergic symptoms such as dry mouth, flushing, tachycardia, urinary retention, and confusion; management is supportive.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration of treatment. Avoid driving or operating heavy machinery if you feel dizzy or drowsy. Avoid alcohol consumption while taking this medicine as it may increase the risk of liver damage and drowsiness. Inform your doctor if you have glaucoma, myasthenia gravis, kidney or liver disease, or difficulty urinating. Do not use this medicine for prolonged periods without medical supervision. Keep out of reach of children. Store at room temperature away from direct sunlight and moisture.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more prone to anticholinergic side effects such as confusion, urinary retention, and constipation. Use with caution and lower doses may be needed.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before taking this medicine. Paracetamol is generally considered safe, but dicyclomine should be used only if clearly needed.
🏥 Post-Surgery Considerations
Consult your doctor before using this medicine after surgery, as it may affect bowel motility and interact with other medications.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, as it may cause dry mouth and interact with anesthetics.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise if you feel dizzy or drowsy. Light activities like walking are generally safe. Consult your doctor before starting any new exercise regimen.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness or blurred vision, affecting your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It may also cause dry mouth, so keep water handy.
🛑 When to Stop This Medicine
Do not stop this medicine abruptly without consulting your doctor. If you experience severe side effects or your symptoms resolve, your doctor may advise tapering or stopping. Always follow medical guidance.
📅 Long-Term Use Effects
Long-term use of this medicine should be under medical supervision. Prolonged use of dicyclomine may lead to tolerance or increased anticholinergic effects. Paracetamol, if taken in high doses over time, can cause liver damage. Regular monitoring of liver and kidney function may be advised.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Low-FODMAP diet can help manage IBS symptoms.
Evidence: Well-establishedYoga, meditation, and counseling can reduce stress-related IBS flares.
Evidence: ModerateMay improve gut health and reduce symptoms in some patients.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interactions with vaccines are established. However, consult your doctor before any vaccination if you are unwell.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from light and moisture. If traveling across time zones, adjust dosing schedule as advised by your doctor. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts relieving cramps within 1-2 hours, and pain relief may begin within 30-60 minutes.
A: It is best taken with food to reduce stomach upset.
A: Consult your doctor before combining with other painkillers, especially those containing paracetamol, to avoid overdose.
🤔 Common Patient Concerns
🔄 Substitutes for coligan 20mg/325mg tablet
View AllAlternative brands with exact same active ingredient:
-
spasmover p tabletCachet Pharmaceuticals Pvt Ltd ₹3.72 60.8% CHEAPER
-
nt spas tabletIntas Pharmaceuticals Ltd ₹4.45 53.2% CHEAPER
-
spasidex tabletWockhardt Ltd ₹4.69 50.6% CHEAPER
-
banalgin 20mg/325mg tabletUni-Pex Pharmaceuticals Pvt Ltd ₹11.00 15.8% COSTLIER
-
spasmak-wh tabletMakers Laboratories Ltd ₹11.34 19.4% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure IBS permanently.
Fact: This medicine provides symptomatic relief but does not cure IBS. Lifestyle and dietary changes are also important. - Myth: It is safe to take extra doses for faster relief.
Fact: Taking extra doses can lead to serious side effects, especially liver damage from paracetamol. Always follow the prescribed dose. - Myth: This medicine is safe for everyone.
Fact: It is not safe for people with certain conditions like glaucoma, myasthenia gravis, or severe liver disease. Consult a doctor before use.
🔄 Alternative Options
Generic Alternatives
- Dicyclomine + Paracetamol generic tablets
Brand Alternatives
- Biospas 20mg/325mg Tablet