cofman junior syrup - Guaifenesin (50mg/5ml) + Terbutaline (1.25mg/5ml) medicine

Ascodex SF Syrup Sugar Free: Complete Medicine Guide

No reviews yet
🏭 Shalman Pharma Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 21, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for individual components; limited for combination.
Reviewed by
SaathiMed Expert Panel | Oct 21, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or swallowing
  • Swelling of face, lips, or throat
  • Chest pain or irregular heartbeat
  • Severe dizziness or fainting
  • Blood in cough or vomit
  • Seizures

If experiencing severe symptoms, call emergency services immediately.

What is cofman junior syrup used for?

This medicine is a sugar-free syrup containing guaifenesin (expectorant) and terbutaline (bronchodilator). It helps relieve cough with thick mucus and improves breathing by opening airways. It is used for conditions like bronchitis. Always take as prescribed by your doctor.

  • Generic Name: Guaifenesin + Terbutaline
  • Manufacturer: Shalman Pharma Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 cofman junior syrup के बारे में (Hindi Summary)

उपयोग: यह दवा गुआइफेनेसिन और टर्बुटालीन का संयोजन है, जिसका उपयोग बलगम वाली खांसी और सांस की तकलीफ में राहत के लिए किया जाता है। यह बलगम को पतला करके निकालने में मदद करती है और श्वास नलियों को खोलती है।

साइड इफेक्ट्स: आम दुष्प्रभावों में जी मिचलाना, सिरदर्द, चक्कर आना, घबराहट, कंपन, धड़कन तेज होना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, सीने में दर्द, अनियमित धड़कन हो सकते हैं।

सुरक्षा सलाह: इस दवा को डॉक्टर की सलाह के बिना न लें। हृदय रोग, उच्च रक्तचाप, मधुमेह, थायरॉइड की समस्या हो तो डॉक्टर को बताएं। गर्भावस्था या स्तनपान के दौरान डॉक्टर से परामर्श करें। शराब न पिएं। वाहन चलाते समय सावधानी बरतें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 cofman junior syrup Uses & Benefits

[{"condition":"Productive cough with thick mucus","description":"Helps loosen and thin mucus, making it easier to cough out, while also opening airways to improve breathing.","evidence":"Well-established"},{"condition":"Bronchitis","description":"Used to relieve cough and improve airflow in acute or chronic bronchitis.","evidence":"Well-established"},{"condition":"Respiratory conditions with bronchospasm and mucus","description":"May be used in conditions like COPD or asthma with mucus, but only under medical supervision.","evidence":"Limited"}]

Off-label uses: []

Primary treatment for: Productive cough with bronchospasm

Also treats: Bronchitis, COPD with mucus, Asthma with mucus (under supervision)

📋 Drug Information

Generic Name(s)Guaifenesin + Terbutaline
Brand NameAsthakind Expectorant Sugar Free
ManufacturerShalman Pharma Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassExpectorant and Bronchodilator
Route of AdministrationOral
StorageStore at room temperature (15-30°C) away from direct sunlight and moisture. Keep out of reach of children.
Shelf Life24 months from date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Shake the bottle well before each use to ensure proper mixing.
2
Use a proper measuring device to avoid inaccurate dosing.
3
Take this medicine with food if it upsets your stomach.
4
Avoid caffeine while taking this medicine as it may increase nervousness.
5
Do not use this medicine for more than 7 days without consulting your doctor.
6
Report any palpitations, tremor, or severe headache to your doctor.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Productive cough
This medicine is commonly prescribed for this.
Likely Use
❌
Dry cough
This medicine is not for dry cough.
Not Primary
✅
Wheezing
Terbutaline helps open airways.
Likely Use

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionGuaifenesin is rapidly absorbed from the gastrointestinal tract. Terbutaline is well absorbed orally, but undergoes some first-pass metabolism.
DistributionGuaifenesin is distributed to body tissues; terbutaline distributes widely, with some protein binding.
Protein BindingTerbutaline is about 25% bound to plasma proteins. Guaifenesin binding is not well established.
MetabolismGuaifenesin is metabolized in the liver. Terbutaline is metabolized in the liver, primarily by conjugation.
Half-LifeGuaifenesin half-life is about 1 hour. Terbutaline half-life is approximately 3-4 hours.
ExcretionBoth drugs and their metabolites are excreted mainly in the urine.
BioavailabilityGuaifenesin oral bioavailability is about 50%. Terbutaline oral bioavailability is about 15% due to first-pass metabolism.
Onset of ActionTerbutaline onset of action is within 30 minutes after oral administration. Guaifenesin onset is not well defined but may take a few hours.
Peak Plasma TimeTerbutaline peak plasma levels occur in 2-4 hours. Guaifenesin peak levels occur in about 1 hour.
Duration of ActionTerbutaline duration of action is about 4-6 hours. Guaifenesin duration is not well established.

How It Works

This medicine combines an expectorant (guaifenesin) and a bronchodilator (terbutaline). Guaifenesin works by increasing the volume and reducing the viscosity of mucus in the respiratory tract, making it easier to clear. Terbutaline stimulates beta-2 adrenergic receptors in the airways, causing relaxation of bronchial smooth muscle and widening of the airways. Together, they help relieve cough and improve breathing.

Mechanism Steps

1
Guaifenesin action: Guaifenesin increases the water content of mucus, making it thinner and less sticky, which helps in coughing it out.
2
Terbutaline action: Terbutaline binds to beta-2 receptors on bronchial smooth muscle, causing relaxation and widening of the airways.
3
Combined effect: The combination facilitates easier breathing and more effective cough clearance.

💡 How to Take cofman junior syrup

Strength: Each 5 ml contains Guaifenesin 50 mg and Terbutaline 1.25 mg.

1Shake the bottle well before use.
2Use a measuring cup or spoon to measure the dose accurately.
3Take orally, with or without food.
4Follow the prescribed dose and frequency.
5Do not exceed the recommended dose.

Dosage Information

Adult DosageThe usual adult dose is 5-10 ml every 4-6 hours as needed, not to exceed 60 ml in 24 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to side effects; dose adjustment may be needed. Consult doctor.
Renal ImpairmentUse with caution in renal impairment; dose adjustment may be necessary. Consult doctor.
Hepatic ImpairmentUse with caution in hepatic impairment; dose adjustment may be necessary. Consult doctor.
Maximum Daily Dose60 ml in 24 hours for adults.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Caffeine
Limit
May increase nervousness and palpitations.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of cofman junior syrup

✅ Common Side Effects

Nervousness (Common (5-10%))
Usually resolves; if persistent, consult doctor.
Tremor (Common (5-10%))
Dose-related; report if bothersome.
Headache (Common (5-10%))
Rest, hydration; consult if severe.
Nausea (Common (5-10%))
Take with food; consult if persistent.
Palpitations (Common (5-10%))
Report to doctor if frequent or bothersome.

🚨 Serious Side Effects

Severe allergic reaction (Rare (<0.1%))
Seek immediate medical attention.
Chest pain (Rare (<0.1%))
Seek immediate medical attention.
Irregular heartbeat (Rare (<0.1%))
Seek immediate medical attention.
Hypokalemia (Rare (<0.1%))
Monitor if on high doses or other risk factors.

⚠️ Rare Side Effects

Seizures
Seek immediate medical attention.
Severe skin reactions
Discontinue and seek medical help.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Propranolol Major
MAO inhibitors Major
Tricyclic antidepressants Major
Diuretics Moderate
Digoxin Moderate
Corticosteroids Moderate
Anticholinergics Minor

🚨 Major Interactions

  • Beta-blockers (e.g., propranolol)
  • MAO inhibitors
  • Tricyclic antidepressants

⚡ Moderate Interactions

  • Diuretics
  • Digoxin
  • Corticosteroids

🍷 Alcohol Interaction

Alcohol may increase drowsiness and dizziness. Avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to guaifenesin or terbutaline","Severe cardiac disease","Hypertension","Diabetes mellitus","Hyperthyroidism","Seizure disorders"]

⚠️ Warnings & Precautions

["Use with caution in patients with cardiovascular disease.","May cause dizziness; avoid driving until effects known.","Not for children under 2 years without medical advice.","Do not exceed recommended dose.","Consult doctor if symptoms persist beyond 7 days."]

🤱 Lactation Safety

Terbutaline is excreted in breast milk; guaifenesin may also be. Consult doctor before use.

💊 Overdose Management

Overdose may cause severe tachycardia, tremor, hypokalemia, and seizures. Seek immediate medical attention. Treatment is supportive and symptomatic.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Additional Safety Advice

General Safety

Before taking this medicine, inform your doctor if you have heart disease, high blood pressure, diabetes, thyroid problems, seizures, or any other medical conditions. Do not take this medicine if you are allergic to guaifenesin, terbutaline, or any other ingredients. This medicine may cause dizziness or drowsiness; avoid driving or operating machinery until you know how it affects you. Do not drink alcohol while taking this medicine as it may increase drowsiness and other side effects. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Do not use this medicine for a longer period than prescribed. Keep out of reach of children. Store at room temperature away from moisture and heat.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to cardiovascular effects. Use with caution and monitor heart rate and blood pressure.

🤰 Pregnancy Planning (TTC)

Consult your doctor if you are planning pregnancy. Terbutaline may affect uterine contractions; use only if clearly needed.

🏥 Post-Surgery Considerations

Consult your doctor before use after surgery, especially if you have heart conditions.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may interact with certain anesthetics.

💚 Lifestyle Tips for Better Results

🏃
Stay well hydrated to help thin mucus.
🥗
Avoid smoking and exposure to pollutants.
😴
Use a humidifier to ease breathing.
💧
Get plenty of rest.
🧘
Practice deep breathing exercises.

🏋️ Exercise Considerations

Avoid strenuous exercise if you experience palpitations or dizziness. Consult your doctor before starting any exercise program.

🥗 Diet Recommendations

Drink warm fluids to soothe the throat.
Avoid cold drinks and ice cream.
Include fruits rich in vitamin C.
Avoid caffeine and alcohol.

💼 Impact on Daily Work & Life

May cause dizziness or drowsiness; avoid driving or operating heavy machinery until you know how it affects you. Take rest if needed.

🛑 When to Stop This Medicine

Stop and consult your doctor if symptoms worsen or if you experience severe side effects. Do not stop abruptly without medical advice.

📅 Long-Term Use Effects

Long-term use of terbutaline may lead to tolerance and reduced effectiveness. Prolonged use of guaifenesin is generally safe but should be under medical supervision. Regular monitoring of heart rate and potassium may be needed.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Steam inhalation

Helps loosen mucus and ease breathing.

Evidence: Traditional
Saline nasal irrigation

Can help clear nasal congestion.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions known. Consult your doctor before any vaccination.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature, away from direct sunlight. If traveling across time zones, adjust dosing schedule as advised by your doctor. Check customs regulations for carrying medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with acute bronchitis
He was prescribed this medicine for a productive cough and wheezing. After 2 days, his cough became more productive and breathing improved. He experienced mild tremor initially, which subsided.
💡 Lesson: Take the medicine as prescribed and report any persistent side effects.
👤 A 50-year-old woman with COPD exacerbation
She used this medicine along with other treatments. It helped loosen mucus and ease breathing. She was advised to monitor her heart rate due to palpitations.
💡 Lesson: Regular monitoring and adherence to prescribed dose are important.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Terbutaline starts working within 30 minutes, while guaifenesin may take a few hours to thin mucus.

Q: Can I take it with other cough medicines?

A: Consult your doctor before combining with other cough medicines to avoid interactions.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my heart?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for cofman junior syrup

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure any type of cough.
    Fact: It is only for productive cough with mucus and bronchospasm; not for dry cough.
  • Myth: It is safe to take without prescription.
    Fact: It contains terbutaline, which can cause serious side effects; use only under medical advice.

🔄 Alternative Options

Generic Alternatives

  • Guaifenesin + Terbutaline syrup (various manufacturers)

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Guaifenesin 50mg/5ml + Terbutaline 1.25mg/5ml","key_feature":"Sugar-free, dual action"},{"medicine":"Guaifenesin + Salbutamol","composition":"Guaifenesin + Salbutamol","key_feature":"Alternative bronchodilator"}]

😊 Was this information helpful?

Browse Medicines A-Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory