Acirid 1.53gm Syrup: Complete Guide to Uses, Dosage, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in urine or stool
- Severe abdominal or flank pain
- High fever with chills
- Difficulty breathing or chest pain
- Swelling of face, lips, or throat
- Decreased urine output or no urination
- Confusion, muscle twitching, or seizures
- Irregular heartbeat or palpitations
If experiencing severe symptoms, call emergency services immediately.
What is alkashal 1.53gm syrup used for?
This medicine is a urinary alkalinizer that contains disodium hydrogen citrate. It works by making urine less acidic, which helps relieve burning and pain during urination, especially in urinary tract infections. It is also used to prevent uric acid kidney stones. It is not an antibiotic and does not cure infections; it only provides symptom relief.
- Generic Name: Disodium Hydrogen Citrate (1.53gm)
- Manufacturer: Shalman Pharma Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 alkashal 1.53gm syrup के बारे में (Hindi Summary)
उपयोग: यह दवा मूत्र पथ के संक्रमण में जलन और दर्द से राहत दिलाने के लिए इस्तेमाल की जाती है। यह पेशाब को कम अम्लीय बनाकर काम करती है, जिससे पेशाब करते समय होने वाली जलन कम होती है। इसके अलावा, यह यूरिक एसिड की पथरी को रोकने और घोलने में भी मदद करती है। यह दवा संक्रमण को ठीक नहीं करती, बल्कि लक्षणों से राहत देती है, इसलिए एंटीबायोटिक्स की जरूरत पड़ सकती है।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में मतली, उल्टी, दस्त, पेट में गैस या सूजन, और ज्यादा प्यास लगना शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। कभी-कभी गंभीर एलर्जी, इलेक्ट्रोलाइट असंतुलन या गुर्दे की कार्यक्षमता में कमी हो सकती है। अगर आपको सांस लेने में तकलीफ, चेहरे या गले में सूजन, दिल की धड़कन अनियमित, या पेशाब कम आना जैसे लक्षण दिखें, तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी सभी दवाओं और स्वास्थ्य समस्याओं के बारे में बताएं। अगर आपको हाई ब्लड प्रेशर, दिल की बीमारी, या गुर्दे की बीमारी है, तो इस दवा का इस्तेमाल सावधानी से करें क्योंकि इसमें सोडियम होता है। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर की सलाह के बिना इसका इस्तेमाल न करें। एंटीबायोटिक्स के साथ लेते समय कम से कम 2 घंटे का अंतर रखें। अगर 2 दिन में आराम न मिले तो डॉक्टर से संपर्क करें।
💊 alkashal 1.53gm syrup Uses & Benefits
[{"condition":"Urinary tract infections (symptomatic relief)","description":"This medicine helps relieve burning and pain during urination by making the urine less acidic.","evidence":"Well-established"},{"condition":"Metabolic acidosis (mild to moderate)","description":"It can be used to correct mild metabolic acidosis by providing bicarbonate precursors.","evidence":"Established"},{"condition":"Uric acid kidney stones (prevention)","description":"Alkalinizing urine helps dissolve uric acid stones and prevent their formation.","evidence":"Established"},{"condition":"Cystitis (interstitial)","description":"May provide symptomatic relief in interstitial cystitis by reducing urine acidity.","evidence":"Limited"}]
Off-label uses: [{"condition":"Chemotherapy-induced hemorrhagic cystitis (prevention)","description":"Sometimes used off-label to alkalinize urine and reduce bladder toxicity from certain chemotherapy drugs like cyclophosphamide.","evidence":"Limited"},{"condition":"Rhabdomyolysis (prevention of kidney injury)","description":"Urine alkalinization may be used off-label to prevent kidney damage in rhabdomyolysis.","evidence":"Limited"}]
Primary treatment for: Urinary tract infections (symptomatic relief)
Also treats: Metabolic acidosis, Uric acid kidney stones, Interstitial cystitis
📋 Drug Information
| Generic Name(s) | Disodium Hydrogen Citrate (1.53gm) |
| Brand Name | alkashal 1.53gm syrup |
| Manufacturer | Shalman Pharma Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | UROLOGY |
| Action Class | Uricosuric agent-gout |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a cool, dry place, away from direct sunlight. Keep the bottle tightly closed. Do not freeze. |
| Shelf Life | 24 months from the date of manufacture, or as indicated on the packaging. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by providing citrate ions, which are metabolized in the body to bicarbonate. Bicarbonate acts as a buffer to neutralize excess acid in the urine, thereby increasing urinary pH. This alkalinization helps reduce the irritation of the bladder and urethra caused by acidic urine, providing relief from burning and pain. Additionally, by making the urine less acidic, it creates an environment that is less favorable for the formation of certain types of kidney stones, such as uric acid stones, and may help dissolve existing ones. The increase in urinary pH also enhances the excretion of certain drugs and can help in conditions like metabolic acidosis by replenishing bicarbonate stores.
Mechanism Steps
💡 How to Take alkashal 1.53gm syrup
Strength: Syrup containing disodium hydrogen citrate 1.53 g per dose (typically per 10 mL or as specified on the label).
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 10-15 mL (approximately 1.53 g of disodium hydrogen citrate) taken 3 to 4 times daily, depending on the condition being treated. For urinary tract infections, it is often taken every 6 to 8 hours. The dose may be adjusted by your doctor based on your kidney function, sodium levels, and response to treatment. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the sodium load and electrolyte effects of this medicine. Dose should be adjusted based on renal function and monitored closely. Consult a doctor for appropriate dosing. |
| Renal Impairment | In patients with mild to moderate renal impairment, dose adjustment may be necessary. This medicine is contraindicated in severe renal impairment (eGFR <30 mL/min). Consult a nephrologist for guidance. |
| Hepatic Impairment | No specific dose adjustment is established for hepatic impairment. Use with caution in severe liver disease and monitor for signs of citrate accumulation. |
| Maximum Daily Dose | The maximum daily dose is not established from available information. Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of alkashal 1.53gm syrup
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Tetracycline | Major | |
| Ciprofloxacin | Major | |
| Lithium | Major | |
| Amphetamines | Major | |
| Furosemide | Moderate | |
| Hydrochlorothiazide | Moderate | |
| Enalapril | Moderate | |
| Prednisolone | Moderate | |
| Aluminum hydroxide | Minor | |
| Ferrous sulfate | Minor |
🚨 Major Interactions
- Tetracycline antibiotics (e.g., doxycycline, tetracycline)
- Fluoroquinolone antibiotics (e.g., ciprofloxacin, levofloxacin)
- Lithium
- Amphetamines
⚡ Moderate Interactions
- Diuretics (e.g., furosemide, hydrochlorothiazide)
- Corticosteroids
- ACE inhibitors (e.g., enalapril, lisinopril)
🍷 Alcohol Interaction
Alcohol may worsen dehydration and increase the risk of electrolyte imbalance. It is advisable to avoid or limit alcohol consumption while taking this medicine, especially if you have a urinary tract infection, as alcohol can irritate the bladder and worsen symptoms.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Severe renal impairment (eGFR
⚠️ Warnings & Precautions
["Contains sodium; caution in hypertension, heart failure, or edema.","May cause electrolyte imbalances; monitor if used long-term.","Not a substitute for antibiotics in urinary tract infections.","Consult doctor if symptoms persist beyond 2 days.","Use with caution in patients with kidney stones (except uric acid stones).","May interfere with certain laboratory tests (e.g., urine pH, electrolytes).","Do not use in children under 12 years without medical advice."]
🤱 Lactation Safety
It is not known whether disodium hydrogen citrate passes into breast milk. Consult your doctor before using this medicine while breastfeeding. It is likely compatible, but medical advice is recommended.
💊 Overdose Management
Overdose may cause metabolic alkalosis, hypernatremia, and electrolyte disturbances. Symptoms include nausea, vomiting, confusion, muscle twitching, and seizures. If overdose is suspected, seek immediate medical attention. Treatment is supportive and may include intravenous fluids and electrolyte correction. Dialysis may be considered in severe cases.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Before taking this medicine, inform your doctor if you have any allergies, especially to citrates or any other medications. This medicine contains sodium, so it should be used with caution in people with high blood pressure, heart failure, or kidney disease, as it may cause fluid retention or worsen these conditions. Do not take this medicine if you are on a strict low-salt diet unless your doctor approves. If you are pregnant or breastfeeding, consult your doctor before use. This medicine may interact with certain antibiotics (such as tetracyclines and fluoroquinolones) by reducing their absorption; therefore, maintain a gap of at least 2 hours between taking this medicine and those antibiotics. Do not exceed the recommended dose. If your symptoms persist for more than 2 days or worsen, contact your doctor, as you may need additional treatment for an underlying infection. Keep this medicine out of reach of children. Store it in a cool, dry place, away from direct sunlight. Do not use it after the expiry date.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more susceptible to electrolyte imbalances and fluid retention due to reduced kidney function. Use this medicine with caution, and monitor renal function and electrolytes regularly. Lower doses may be needed.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before using this medicine. It is generally considered safe for short-term use, but your doctor will weigh the benefits and risks. Maintain a healthy lifestyle and discuss any medications you are taking.
🏥 Post-Surgery Considerations
After surgery, this medicine may be used to alkalinize urine, especially if you have a urinary catheter or are at risk of uric acid stones. Follow your surgeon's instructions regarding dosage and duration. Inform your surgical team about all medicines you are taking.
🦷 Dental Procedures
No specific precautions are needed for dental procedures. However, inform your dentist about all medicines you are taking. Maintain good oral hygiene.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
There are no specific exercise restrictions while taking this medicine. However, if you have a urinary tract infection, strenuous exercise may worsen discomfort. Listen to your body and rest if needed. Stay hydrated during exercise.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine generally does not affect your ability to drive or operate machinery. However, if you experience dizziness or drowsiness (rare), avoid these activities until you know how the medicine affects you. It should not interfere with your daily work routine.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if your symptoms do not improve within 2 days, if they worsen, or if you experience any serious side effects such as allergic reactions, irregular heartbeat, or decreased urine output. Do not stop prescribed antibiotics without completing the course, even if you feel better.
📅 Long-Term Use Effects
Long-term use of this medicine without monitoring can lead to electrolyte imbalances such as hypernatremia (high sodium) and hypokalemia (low potassium), metabolic alkalosis, and fluid retention. It may also worsen kidney function in susceptible individuals. If used for preventing uric acid stones, regular monitoring of urine pH and serum electrolytes is recommended. Do not use for more than 2 weeks without medical advice.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Drinking plenty of water helps dilute urine and reduce burning.
Evidence: Well-establishedMay help prevent urinary tract infections but not treat active ones.
Evidence: LimitedCan support gut and urinary health, especially when taking antibiotics.
Evidence: Emerging💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. You can receive vaccinations as scheduled. However, if you have an active infection, consult your doctor about timing.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription in case of customs checks. Store it in a cool, dry place away from direct sunlight. If traveling across time zones, continue taking the medicine at regular intervals as prescribed; you may need to adjust the timing gradually. Keep enough supply for your entire trip. If you are flying, pack it in your carry-on luggage to avoid temperature extremes in checked baggage.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within 1 to 2 hours after taking a dose. You may notice relief from burning and pain during urination within a few hours. However, if symptoms persist beyond 2 days, consult your doctor.
A: Yes, but you must maintain a gap of at least 2 hours between this medicine and antibiotics like tetracyclines or fluoroquinolones, as this medicine can reduce their absorption. Always inform your doctor about all medicines you are taking.
A: Consult your doctor before taking this medicine during pregnancy. It is generally considered safe for short-term use, but medical advice is essential.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
A: Long-term use should only be done under medical supervision, as it can cause electrolyte imbalances and high sodium levels. Regular monitoring of blood tests may be required.
🤔 Common Patient Concerns
🔄 Substitutes for alkashal 1.53gm syrup
View AllAlternative brands with exact same active ingredient:
-
sincosol syrupShiwalic Formulations Pvt Ltd ₹29.93 45.9% CHEAPER
-
vrialka 1.53gm syrupVrinda Life ₹42.19 23.7% CHEAPER
-
alkadium syrupBest Biotech ₹46.88 15.2% CHEAPER
-
cytrila syrupLuxica Pharma Inc. ₹50.00 9.6% CHEAPER
-
aerosol 1.53gm syrupAerozest Life Science ₹51.56 6.8% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Acirid syrup can cure urinary tract infections.
Fact: This medicine only relieves symptoms like burning; it does not kill bacteria. Antibiotics are needed to cure the infection. - Myth: It is safe to take acirid syrup for a long time without monitoring.
Fact: Long-term use can cause electrolyte imbalances and high sodium levels. Regular monitoring is required. - Myth: Acirid syrup is safe for everyone.
Fact: It is not safe for people with severe kidney or heart disease, or those on a low-sodium diet.
🔄 Alternative Options
Generic Alternatives
- Disodium hydrogen citrate syrup (generic)
Brand Alternatives
- Acirid 1.53gm syrup