coblin od 1500mcg tablet - Uses, Price, Side Effects & Substitutes
What is coblin od 1500mcg tablet used for?
Alamin Injection (Methylcobalamin) is used to treat VITAMINS MINERALS NUTRIENTS. It contains Methylcobalamin (1500mcg), which Methylcobalamin acts as a cofactor for methionine synthase, converting homocyste. Always consult your doctor before use. Take as prescribed.
- Generic Name: Methylcobalamin
- Manufacturer: Intecare
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ coblin od 1500mcg tablet Uses & Benefits
Pernicious anemia, vitamin B12 deficiency due to malabsorption (e.g., gastrectomy, Crohn's disease), megaloblastic anemia, diabetic neuropathy, peripheral neuropathy, subacute combined degeneration of the spinal cord, and as a nutritional supplement.
Off-label uses: Tinnitus, chronic fatigue syndrome, sleep disorders, Alzheimer's disease, multiple sclerosis, autism spectrum disorders (limited evidence).
๐ Drug Information
| Generic Name(s) | Methylcobalamin |
| Brand Name | Alamin Injection |
| Manufacturer | Intecare |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | VITAMINS MINERALS NUTRIENTS |
| Action Class | Vitamins |
| Route of Administration | Intramuscular injection only; not for intravenous use. |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from light; do not freeze. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Methylcobalamin acts as a cofactor for methionine synthase, converting homocysteine to methionine, and for methylmalonyl-CoA mutase, converting methylmalonyl-CoA to succinyl-CoA, essential for DNA synthesis, myelin formation, and red blood cell production.
Mechanism Steps
๐ก How to Take coblin od 1500mcg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of coblin od 1500mcg tablet
โ Common Side Effects
- Injection site pain
- Redness
- Swelling
- Itching
- Mild diarrhea
- Headache
๐จ Serious Side Effects
- Anaphylaxis
- Hypersensitivity reactions
- Pulmonary edema
- Congestive heart failure (with rapid correction of severe anemia)
- Hypokalemia (during initial therapy for megaloblastic anemia)
โ ๏ธ Rare Side Effects
- Peripheral vascular thrombosis
- Polycythemia vera
- Leber's disease exacerbation
- Acneiform eruptions
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Chloramphenicol | Major | May decrease response to methylcobalamin by inhibiting erythropoiesis. |
| Colchicine | Major | May reduce absorption of vitamin B12. |
| Neomycin | Major | May decrease vitamin B12 absorption. |
| Aminosalicylic acid | Major | May reduce vitamin B12 absorption. |
| Potassium supplements | Major | May decrease vitamin B12 absorption. |
| Metformin | Moderate | Long-term use may reduce vitamin B12 absorption. |
| Proton pump inhibitors | Moderate | May decrease vitamin B12 absorption with prolonged use. |
| H2 receptor antagonists | Moderate | May reduce vitamin B12 absorption. |
| Oral contraceptives | Moderate | May lower serum vitamin B12 levels. |
| Alcohol | Minor | Chronic use may impair vitamin B12 absorption. |
| Tobacco | Minor | May decrease vitamin B12 levels. |
| Caffeine | Minor | No significant interaction; may slightly increase excretion. |
๐จ Major Interactions
- Chloramphenicol
- Colchicine
- Neomycin
- Aminosalicylic acid
- Potassium supplements
โก Moderate Interactions
- Metformin
- Proton pump inhibitors
- H2 receptor antagonists
- Oral contraceptives
โน๏ธ Minor Interactions
- Alcohol
- Tobacco
- Caffeine
๐ฝ๏ธ Food Interactions
No significant food interactions; absorption unaffected by food when injected.
๐ท Alcohol Interaction
Chronic alcohol consumption may reduce vitamin B12 absorption and increase requirements.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to methylcobalamin or any component; Leber's disease (optic atrophy) due to cyanocobalamin; caution in polycythemia vera.
๐ Monitoring Parameters
Serum vitamin B12 levels, homocysteine levels, methylmalonic acid levels, complete blood count (CBC), reticulocyte count, neurological examination.
๐คฑ Lactation Safety
Excreted in breast milk; considered compatible with breastfeeding at recommended doses.
๐ Overdose Management
No specific antidote; treatment is supportive and symptomatic; excess is excreted in urine.
โฐ Missed Dose
Administer as soon as remembered; if close to next dose, skip missed dose and resume regular schedule; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for coblin od 1500mcg tablet
View AllAlternative brands with exact same active ingredient (Methylcobalamin (1500mcg)):
-
my 12 od injectionZeelab Pharmacy Pvt Ltd โน8.00 91.6% CHEAPER
-
actobal-m injectionFitwel Pharmaceuticals Private Limited โน23.44 75.3% CHEAPER
-
becomin injectionBipin Drug House โน24.00 74.7% CHEAPER
-
neuroage 1500mcg injectionAllenge India โน24.00 74.7% CHEAPER
-
nurokind od injectionMankind Pharma Ltd โน24.99 73.7% CHEAPER
-
cobarax 1500mcg injectionRax Health Care Pvt Ltd โน25.00 73.7% CHEAPER
-
my 12 od tabletZeelab Pharmacy Pvt Ltd โน25.00 73.7% CHEAPER
-
multimore 1500mcg injectionMits Healthcare Pvt Ltd โน25.00 73.7% CHEAPER
-
melbin 1500 injectionMeltic Healthcare Pvt Ltd โน25.00 73.7% CHEAPER
-
neuroleen 1500mcg injectionLeenate Pharma Pvt Ltd โน25.00 73.7% CHEAPER
Medical Note: Always consult your doctor before switching medications.