cobadef injection
What is cobadef injection used for?
This medicine contains Methylcobalamin (1500mcg) + Vitamin B6 (Pyridoxine) (100mg) and is used to treat VITAMINS MINERALS NUTRIENTS. Methylcobalamin acts as a cofactor for methionine synthase, essential for myelin synthesis; Pyridoxi. Always consult your doctor before use.
- Generic Name: Methylcobalamin + Vitamin B6 (Pyridoxine)
- Manufacturer: Clabert Lifesciences Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Category A
- Prescription Required: Yes
💊 cobadef injection Uses & Benefits
Peripheral neuropathy, megaloblastic anemia, homocysteinemia, vitamin B12 and B6 deficiency.
Off-label uses: Chronic fatigue syndrome, diabetic neuropathy, carpal tunnel syndrome.
📋 Drug Information
| Generic Name(s) | Methylcobalamin + Vitamin B6 (Pyridoxine) |
| Brand Name | Alnacob Plus Injection |
| Manufacturer | Clabert Lifesciences Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | VITAMINS MINERALS NUTRIENTS |
| Action Class | Vitamins/Minerals/Nutrients |
| Route of Administration | Intramuscular injection |
| Storage | Store at 2-8°C, protect from light. |
| Shelf Life | As per manufacturer |
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Methylcobalamin acts as a cofactor for methionine synthase, essential for myelin synthesis; Pyridoxine is a cofactor for enzymes in neurotransmitter synthesis and homocysteine metabolism.
Mechanism Steps
💡 How to Take cobadef injection
Follow your doctor's prescription exactly.
⚠️ Side Effects of cobadef injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Levodopa | Major | Pyridoxine reduces levodopa efficacy by increasing peripheral metabolism. |
| Chloramphenicol | Major | May impair response to vitamin B12 therapy. |
| Colchicine | Major | May decrease absorption of vitamin B12. |
| Phenytoin | Moderate | Pyridoxine may decrease phenytoin levels. |
| Oral contraceptives | Moderate | May increase requirement for pyridoxine. |
| Isoniazid | Moderate | May cause pyridoxine deficiency. |
| Penicillamine | Minor | May increase pyridoxine requirement. |
| Cycloserine | Minor | May increase pyridoxine requirement. |
🚨 Major Interactions
- Levodopa
- Chloramphenicol
- Colchicine
⚡ Moderate Interactions
- Anticonvulsants (phenytoin, phenobarbital)
- Oral contraceptives
- Isoniazid
🍷 Alcohol Interaction
Chronic alcohol use may reduce absorption of vitamin B6.
🛡️ Safety & Warnings
🚫 Contraindications
Hypersensitivity to any component; severe renal impairment (for high doses of pyridoxine).
🤱 Lactation Safety
Safe; both vitamins are excreted in breast milk but not harmful.
💊 Overdose Management
Discontinue injection; symptomatic treatment; pyridoxine overdose may cause neuropathy.
⏰ Missed Dose
Administer as soon as remembered; if close to next dose, skip missed dose.
🔄 Substitutes for cobadef injection
View AllAlternative brands with exact same active ingredient:
-
nervic gold injectionUnimarck Pharma India Ltd ₹24.00 63.4% CHEAPER
-
aynavit-forte injectionAyns Pharma ₹25.60 61% CHEAPER
-
beconerve plus aq injectionFascin Pharmaceuticals ₹29.90 54.4% CHEAPER
-
methconix-plus injectionMedinix Pharmaceutical Pvt Ltd ₹30.00 54.3% CHEAPER
-
motoneuron injectionMbco Lifesciences Pvt Ltd ₹30.00 54.3% CHEAPER
Medical Note: Always consult your doctor before switching medications.