Clyora Syrup: Comprehensive Guide To Uses, Side Effects, And Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe headache or blurred vision
- Chest pain or palpitations
- Difficulty breathing or swelling of face, lips, or throat
- Inability to urinate
- Seizures or severe drowsiness
- Yellowing of skin or eyes
If experiencing severe symptoms, call emergency services immediately.
What is clyora syrup used for?
This medicine is a combination of chlorpheniramine (an antihistamine) and phenylephrine (a decongestant) used to treat symptoms of allergies and the common cold, such as runny nose, sneezing, and nasal congestion. It works by blocking histamine and constricting nasal blood vessels. It may cause drowsiness, so avoid driving. Do not use for more than 7 days without consulting a doctor.
- Generic Name: Chlorpheniramine Maleate + Phenylephrine
- Manufacturer: Clyde Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 clyora syrup के बारे में (Hindi Summary)
उपयोग: यह दवा एलर्जी और सर्दी-जुकाम के लक्षणों जैसे नाक बहना, छींक आना, नाक बंद होना और आंखों में खुजली को कम करने के लिए इस्तेमाल की जाती है। इसमें क्लोरफेनिरामाइन (एंटीहिस्टामिन) और फेनिलएफ्रिन (डिकंजेस्टेंट) होते हैं। यह दवा नाक की रक्त वाहिकाओं को सिकोड़कर और हिस्टामिन को रोककर काम करती है। ध्यान दें कि यह दवा नींद ला सकती है, इसलिए वाहन चलाने से बचें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, चक्कर आना, मुंह सूखना, धुंधली दृष्टि, जी मिचलाना और पेट खराब होना शामिल हैं। गंभीर दुष्प्रभावों में हृदय गति बढ़ना, रक्तचाप बढ़ना, पेशाब रुकना और एलर्जी प्रतिक्रिया हो सकती है। यदि कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर की सलाह के अनुसार ही लें। इसकी खुराक न बढ़ाएं। दवा लेने के बाद नींद आ सकती है, इसलिए वाहन चलाने या मशीन चलाने से बचें। शराब का सेवन न करें। यदि आपको उच्च रक्तचाप, हृदय रोग, मधुमेह, ग्लूकोमा या पेशाब में कठिनाई है तो डॉक्टर को बताएं। 7 दिनों से अधिक इस दवा का उपयोग बिना डॉक्टर की सलाह के न करें।
💊 clyora syrup Uses & Benefits
[{"condition":"Allergic rhinitis","description":"Relieves sneezing, runny nose, itchy and watery eyes, and nasal congestion associated with seasonal or perennial allergies.","evidence":"Well-established"},{"condition":"Common cold","description":"Provides symptomatic relief of nasal congestion, sneezing, and runny nose due to viral upper respiratory infections.","evidence":"Well-established"},{"condition":"Vasomotor rhinitis","description":"Helps reduce nasal congestion and rhinorrhea in non-allergic rhinitis.","evidence":"Limited"}]
Off-label uses: [{"condition":"Pruritus","description":"Sometimes used off-label to relieve itching due to allergic skin conditions, but not a primary treatment.","evidence":"Limited"}]
Primary treatment for: Allergic rhinitis
Also treats: Common cold, Vasomotor rhinitis
📋 Drug Information
| Generic Name(s) | Chlorpheniramine Maleate + Phenylephrine |
| Brand Name | Ascoril Flu Syrup |
| Manufacturer | Clyde Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Antihistamine + Decongestant |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep the bottle tightly closed. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients. Chlorpheniramine maleate is a first-generation antihistamine that competitively blocks histamine H1 receptors, reducing allergic responses such as sneezing, runny nose, and itching. Phenylephrine is an alpha-1 adrenergic receptor agonist that causes vasoconstriction in the nasal mucosa, leading to decreased swelling and congestion. The combination provides both antihistaminic and decongestant effects.
Mechanism Steps
💡 How to Take clyora syrup
Strength: Each 5 mL contains Chlorpheniramine Maleate 2 mg and Phenylephrine 5 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 5 to 10 mL (1 to 2 teaspoons) every 4 to 6 hours as needed, not to exceed 6 doses in 24 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine. Use with caution and consider lower doses. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Dose adjustment may be required in patients with renal impairment. Consult a doctor for individualized dosing. |
| Hepatic Impairment | Dose adjustment may be required in patients with hepatic impairment. Consult a doctor for individualized dosing. |
| Maximum Daily Dose | The maximum daily dose for adults is 60 mL (12 teaspoons) in 24 hours. Do not exceed the recommended dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of clyora syrup
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| MAOIs | Major | |
| Tricyclic antidepressants | Major | |
| Beta-blockers | Moderate | |
| CNS depressants | Moderate | |
| Anticholinergics | Minor |
🚨 Major Interactions
- Monoamine oxidase inhibitors (MAOIs)
- Tricyclic antidepressants
⚡ Moderate Interactions
- Beta-blockers
- Central nervous system depressants
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine because it can enhance the sedative effects of chlorpheniramine and increase the risk of dizziness, drowsiness, and impaired coordination.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to chlorpheniramine, phenylephrine, or any component of the formulation.","Severe hypertension or coronary artery disease.","Narrow-angle glaucoma.","Urinary retention or prostatic hypertrophy.","Concurrent use with monoamine oxidase inhibitors (MAOIs) or within 14 days of stopping MAOI therapy.","Newborns and premature infants."]
⚠️ Warnings & Precautions
["May cause drowsiness; avoid driving or operating machinery until effects are known.","Avoid alcohol and other CNS depressants.","Use with caution in patients with hypertension, cardiovascular disease, diabetes, thyroid disorders, or glaucoma.","Do not use for longer than 7 days without medical advice.","Elderly patients may be more sensitive to anticholinergic and sedative effects.","Keep out of reach of children."]
🤱 Lactation Safety
Chlorpheniramine and phenylephrine may pass into breast milk. Consult a doctor before use during breastfeeding; caution is advised as it may cause drowsiness in the infant.
💊 Overdose Management
Overdose may cause severe drowsiness, seizures, respiratory depression, hypertension, or cardiac arrhythmias. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Do not exceed the recommended dose of this medicine. Avoid driving or operating heavy machinery until you know how this medicine affects you, as it may cause drowsiness. Avoid consuming alcohol or other central nervous system depressants while taking this medicine, as they can increase drowsiness and dizziness. Inform your doctor if you have high blood pressure, heart disease, diabetes, thyroid problems, glaucoma, or difficulty urinating. Do not use this medicine for longer than 7 days without consulting a doctor. Keep out of reach of children. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more susceptible to anticholinergic effects, drowsiness, and urinary retention. Use with caution and consider lower doses. Monitor blood pressure regularly.
🤰 Pregnancy Planning (TTC)
Consult your doctor before using this medicine if you are pregnant, planning to become pregnant, or breastfeeding. The safety of this combination in pregnancy is not well established.
🏥 Post-Surgery Considerations
This medicine may interact with anesthetics and other medications used during surgery. Inform your surgeon and anesthesiologist about all medicines you are taking before surgery.
🦷 Dental Procedures
This medicine may cause dry mouth, which can increase the risk of dental caries. Maintain good oral hygiene and inform your dentist about this medicine before any dental procedure.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or activities requiring alertness until you know how this medicine affects you, as it may cause drowsiness and dizziness.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness and impair concentration, affecting your ability to drive or operate machinery. Avoid tasks requiring mental alertness until you know how it affects you.
🛑 When to Stop This Medicine
Stop taking this medicine and consult a doctor if symptoms persist beyond 7 days, worsen, or if you experience severe side effects such as palpitations, difficulty urinating, or allergic reactions.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended without medical supervision. Prolonged use may lead to tolerance, dependence, and increased risk of side effects such as hypertension, urinary retention, and cognitive impairment. Regular monitoring of blood pressure and renal function is advised if used for extended periods.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Helps clear nasal passages and reduce congestion without medication.
Evidence: Well-establishedReducing exposure to allergens can decrease reliance on medication.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with vaccines. However, if you have a fever or acute illness, consult your doctor before vaccination.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of the prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing intervals as advised by your doctor. Check customs regulations for carrying medications.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts working within 30 to 60 minutes after oral administration.
A: Yes, you can take it with or without food. Taking it with food may reduce stomach upset.
A: Pediatric dosing is not established from available information. Consult a pediatrician.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This medicine can cure the common cold.
Fact: This medicine only relieves symptoms; it does not cure the underlying viral infection. - Myth: It is safe to take this medicine for long periods.
Fact: Prolonged use without medical supervision can lead to side effects and is not recommended.
🔄 Alternative Options
Generic Alternatives
- Chlorpheniramine + Phenylephrine syrup