Clofert Max Tablet (Clomiphene 25 mg): Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Severe or rapidly worsening abdominal pain or bloating.
- Rapid weight gain or swelling of the hands, feet, or face.
- Difficulty breathing or chest discomfort.
- Blurred vision, double vision, or flashing lights.
- Vomiting that does not stop or inability to keep fluids down.
- Yellowing of the skin or eyes, or dark urine.
- Severe headache with visual changes or confusion.
- Sudden swelling of the face, lips, or throat.
If experiencing severe symptoms, call emergency services immediately.
What is clofert 25 tablet used for?
This medicine is an oral fertility tablet containing clomiphene 25 mg. It works by blocking estrogen receptors in the brain, which raises follicle-stimulating hormone and luteinizing hormone levels and helps the ovaries release an egg. It is used mainly for ovulation problems in women trying to conceive and must be taken only under medical supervision.
- Generic Name: Clomiphene
- Manufacturer: Maneesh Pharmaceuticals Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 clofert 25 tablet के बारे में (Hindi Summary)
उपयोग: यह दवा मुख्य रूप से महिलाओं में ओव्यूलेशन यानी अंडोत्सर्ग की समस्या के इलाज के लिए दी जाती है। जिन महिलाओं को हर महीने अंडा नहीं बनता या अनियमित रूप से बनता है, उनमें यह दवा अंडे के बनने और निकलने की प्रक्रिया को बढ़ावा देती है। यह पॉलीसिस्टिक ओवरी सिंड्रोम, अनियमित मासिक धर्म और कुछ मामलों में पुरुषों में टेस्टोस्टेरोन की कमी में भी विशेषज्ञ की सलाह पर इस्तेमाल की जा सकती है। यह दवा गर्भधारण की संभावना बढ़ाने में मदद करती है, लेकिन गर्भधारण की गारंटी नहीं देती। इसे डॉक्टर की सलाह के बिना शुरू या बंद नहीं करना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में गर्मी लगना, पेट में भारीपन या दर्द, जी मिचलाना, स्तनों में कोमलता, सिरदर्द और मूड में बदलाव शामिल हैं। कुछ महिलाओं को धुंधला दिखाई देना या आंखों में परेशानी हो सकती है, और ऐसा होने पर तुरंत डॉक्टर से मिलना चाहिए। बहुत कम मामलों में ओवेरियन हाइपरस्टिमुलेशन सिंड्रोम हो सकता है, जिसमें पेट में तेज दर्द, तेजी से वजन बढ़ना, उल्टी और सांस लेने में तकलीफ होती है। यह एक गंभीर स्थिति है और इसमें तुरंत अस्पताल जाना चाहिए।
सुरक्षा सलाह: इस दवा को केवल डॉक्टर की देखरेख में ही लें। अपनी मर्जी से खुराक न बढ़ाएं और न ही इलाज के दिनों को बढ़ाएं। अगर आपको लीवर की बीमारी, असामान्य रक्तस्राव, थायरॉइड या एड्रेनल की समस्या है तो शुरू करने से पहले डॉक्टर को बताएं। आंखों में धुंधलापन, तेज पेट दर्द, तेजी से वजन बढ़ना या सांस लेने में तकलीफ हो तो तुरंत डॉक्टर से संपर्क करें। गर्भावस्था के दौरान यह दवा नहीं लेनी चाहिए। इलाज के दौरान अल्ट्रासाउंड और खून की जांच कराना बहुत जरूरी है। शराब का सेवन न करें और दूसरों के साथ यह दवा साझा न करें।
💊 clofert 25 tablet Uses & Benefits
[{"condition":"Ovulatory dysfunction in women","description":"This medicine is used to induce ovulation in women who do not ovulate regularly, including those with polycystic ovary syndrome, and it is one of the most commonly prescribed first-line oral fertility treatments.","evidence":"Well-established"},{"condition":"Unexplained infertility","description":"Sometimes used to increase the number of eggs released in women with unexplained infertility, often combined with timed intercourse or intrauterine insemination.","evidence":"Moderate"},{"condition":"Male hypogonadism and low sperm count","description":"In selected men, this medicine may be used off-label to raise testosterone and improve sperm production, but only under specialist care.","evidence":"Limited"},{"condition":"Luteal phase defect","description":"Occasionally prescribed to support ovulation and the second half of the menstrual cycle in women with a short luteal phase.","evidence":"Limited"}]
Off-label uses: [{"condition":"Male infertility with low testosterone","description":"Some specialists use this medicine in men to stimulate the pituitary-gonadal axis, but this is not a standard approved use.","evidence":"Limited"},{"condition":"Gynecomastia in men","description":"Rarely used off-label to reduce breast tissue enlargement in men, but evidence is weak and other treatments are preferred.","evidence":"Limited"}]
Primary treatment for: Ovulatory dysfunction and infertility in women
Also treats: Polycystic ovary syndrome, Unexplained infertility, Male hypogonadism, Luteal phase defect
📋 Drug Information
| Generic Name(s) | Clomiphene |
| Brand Name | Axifert 50mg Tablet |
| Manufacturer | Maneesh Pharmaceuticals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GYNAECOLOGICAL |
| Action Class | Partial estrogen agonist |
| Route of Administration | Oral |
| Storage | Store this medicine at room temperature between 15°C and 30°C in a dry place, away from direct sunlight and moisture. Keep it in the original container with the lid tightly closed. |
| Shelf Life | The shelf life is usually 24 to 36 months from the date of manufacture, depending on the pack. Always check the expiry date printed on the pack and do not use the medicine after that date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine acts as a selective estrogen receptor modulator. It binds to estrogen receptors in the hypothalamus and pituitary gland and blocks the normal feedback inhibition by estrogen. As a result, the brain increases its release of gonadotropin-releasing hormone, which in turn raises follicle-stimulating hormone and luteinizing hormone levels. These hormones stimulate the ovaries to recruit and mature follicles, leading to ovulation. In men, the same blocking action at the pituitary can increase luteinizing hormone and follicle-stimulating hormone, which may raise testosterone production and support sperm formation. The exact balance of estrogen agonist and antagonist effects depends on the tissue and on the dose used.
Mechanism Steps
💡 How to Take clofert 25 tablet
Strength: Immediate-release oral tablet containing 25 mg of clomiphene.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is individualized by a qualified clinician based on the indication, the response to previous cycles, and the presence of any liver or hormone problems. A common starting dose is 25 mg to 50 mg once daily for five days, beginning on a day chosen by your doctor, usually early in the menstrual cycle. The dose may be increased in later cycles if ovulation does not occur, but only under medical supervision. Do not self-adjust the dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | This medicine is not intended for use in elderly women beyond the reproductive age group. No specific elderly dosing is established from the available information. |
| Renal Impairment | No specific dose adjustment is established from the available information for people with kidney disease. Use with caution and only under medical supervision. |
| Hepatic Impairment | This medicine should not be used in people with liver disease or unexplained abnormal liver function tests. If liver function is mildly abnormal, the doctor will decide whether treatment is safe. |
| Maximum Daily Dose | The maximum daily dose is usually 100 mg to 150 mg, but this must be determined by a qualified clinician. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of clofert 25 tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Gonadotropins | Major | |
| Estrogen-containing products | Major | |
| Rifampicin | Moderate | |
| Metformin | Moderate | |
| Thyroid hormones | Moderate | |
| Diuretics | Moderate | |
| Paracetamol | Minor | |
| Antacids | Minor |
🚨 Major Interactions
- Other fertility medicines such as gonadotropins
- Hormonal contraceptives and estrogen-containing products
- Liver enzyme-inducing drugs such as rifampicin and some anticonvulsants
⚡ Moderate Interactions
- Thyroid hormones
- Metformin
- Diuretics
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. It can worsen mood swings, increase the risk of liver strain, and add to dehydration, which is particularly important if ovarian hyperstimulation develops. If you drink alcohol regularly, discuss this with your doctor before starting treatment.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known pregnancy.","Liver disease or unexplained abnormal liver function tests.","Unexplained abnormal vaginal bleeding.","Known hypersensitivity to clomiphene or any ingredient of this medicine.","Hormone-sensitive cancers such as breast or endometrial cancer.","Ovarian cysts that are not related to polycystic ovary syndrome.","Previous ovarian hyperstimulation syndrome with this medicine.","Active thyroid or adrenal disease that is not controlled."]
⚠️ Warnings & Precautions
["This medicine should only be used under the supervision of a fertility specialist or a qualified clinician.","Visual symptoms such as blurred vision or double vision require immediate medical attention and may mean the medicine should be stopped.","Ovarian hyperstimulation syndrome is a rare but serious complication that needs urgent care.","Multiple pregnancy, including twins or more, can occur and should be monitored with ultrasound.","Long-term use beyond the recommended number of cycles should be avoided unless specifically advised by a specialist.","This medicine is not a treatment for obesity, and weight loss should be achieved through diet and exercise.","Do not take this medicine if you are already pregnant or if pregnancy has not been excluded.","Inform your doctor about all other medicines, supplements, and herbal products you are taking."]
🤱 Lactation Safety
It is not known whether this medicine passes into breast milk in significant amounts, and it is generally not recommended during breastfeeding. Discuss alternative options with your doctor if you are breastfeeding.
💊 Overdose Management
Overdose of this medicine can cause severe ovarian enlargement, abdominal pain, nausea, vomiting, hot flushes, and visual disturbances. There is no specific antidote, so treatment is supportive and symptom-based. If you suspect an overdose, contact your doctor or a poison control centre immediately and go to the nearest emergency department. Do not try to vomit unless a healthcare professional advises you to do so.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember on the same day. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose. If you miss several doses, contact your doctor for advice before restarting.
Additional Safety Advice
Take this medicine only under the supervision of a fertility specialist or a qualified clinician. Do not increase the dose or extend the treatment course on your own, because higher doses do not necessarily improve results and can increase the risk of ovarian hyperstimulation. Before starting, tell your doctor about any liver problems, abnormal vaginal bleeding, thyroid disease, adrenal disease, or previous ovarian cysts. Report any visual changes, severe pelvic pain, rapid weight gain, or breathing difficulty immediately. This medicine is not safe during pregnancy, so use a reliable barrier method until your doctor confirms that you are not pregnant, unless you are actively trying to conceive under medical guidance. Avoid alcohol while taking this medicine because it can worsen mood changes and liver stress. Keep all follow-up appointments for ultrasound scans and hormone tests, because monitoring is essential for safe use. Do not share this medicine with anyone else, even if they have similar fertility concerns.
👴 Special Considerations for Elderly
💡 For Patients Above 65
This medicine is not intended for use in elderly women beyond the reproductive age group. No specific elderly dosing or safety data are established from the available information.
🤰 Pregnancy Planning (TTC)
This medicine is used to help you conceive, but it should not be taken once you are pregnant. If you are trying to conceive, your doctor will advise you on the correct days to take the medicine and when to test for pregnancy. Use a reliable barrier method until your doctor confirms that you are not pregnant for the current cycle, unless you are actively trying to conceive under medical guidance. If you become pregnant, stop the medicine and contact your doctor immediately.
🏥 Post-Surgery Considerations
If you are planning surgery, tell your surgeon and anaesthetist that you are taking this medicine. There is no specific guidance on stopping this medicine before surgery, but your doctor will decide based on your overall health and the type of procedure.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine. There is no specific interaction with dental anaesthetics, but it is important for your dental team to know about all medicines you take. If you need dental work during treatment, discuss the timing with your doctor.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is generally safe while taking this medicine, but avoid very intense or high-impact workouts if you develop ovarian enlargement or pelvic pain. If you feel dizzy, short of breath, or have severe abdominal discomfort, stop exercising and seek medical advice. Always warm up and cool down, and listen to your body.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
Most people can continue their usual work and daily activities while taking this medicine. However, if you experience blurred vision, dizziness, or significant pelvic pain, avoid driving or operating heavy machinery until you feel better. Mood swings and hot flushes may affect concentration for some women, so plan demanding tasks around your treatment days if possible.
🛑 When to Stop This Medicine
Stop this medicine and contact your doctor immediately if you develop visual disturbances, severe abdominal pain, rapid weight gain, difficulty breathing, or signs of an allergic reaction. Do not stop the medicine on your own for other reasons without consulting your doctor, because the timing of the course is important for ovulation. If you become pregnant, stop the medicine and inform your doctor right away.
📅 Long-Term Use Effects
Long-term use of this medicine beyond the recommended number of cycles is not advised without specialist review. Prolonged use has been associated with a small increase in the risk of ovarian tumours in some studies, although the evidence is not conclusive. Regular monitoring with ultrasound and liver function tests is important if repeated cycles are planned. If pregnancy does not occur after several cycles, your doctor may recommend other fertility treatments such as letrozole, gonadotropins, or assisted reproduction.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
An oral aromatase inhibitor that is often used as an alternative ovulation induction agent, especially in polycystic ovary syndrome.
Evidence: Well-establishedLosing even a small amount of weight can restore ovulation in some women with polycystic ovary syndrome.
Evidence: Well-establishedAn insulin-sensitizing medicine that can improve ovulation when used alone or with clomiphene in polycystic ovary syndrome.
Evidence: ModerateInjectable fertility hormones used when oral medicines are not effective, with closer monitoring.
Evidence: Well-establishedProcedures such as intrauterine insemination or in vitro fertilization may be recommended if oral treatment fails.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no specific vaccine interactions reported with this medicine. Routine vaccinations can generally be given, but inform your doctor about your fertility treatment so that the timing can be planned appropriately.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in the original container with the lid tightly closed
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight and moisture
❌ DON'T
Do not store in the bathroom cabinet
✅ DO
Keep out of reach of children and pets
❌ DON'T
Do not use after the expiry date
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with the prescription label visible. Keep a copy of your prescription and a letter from your doctor if you are travelling internationally, especially if you are carrying more than a personal supply. Store the tablets in a cool, dry place away from direct sunlight, and avoid leaving them in a hot car or checked luggage. If you are crossing time zones, ask your doctor how to adjust the timing of your doses so that the five-day course is completed correctly. Declare the medicine at customs if required, and carry enough for the entire trip plus a few extra days in case of delays.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Ovulation usually occurs about 5 to 10 days after the last dose of a treatment cycle, but the exact timing varies. Your doctor may confirm ovulation with a progesterone test or ultrasound.
A: Yes, this medicine increases the chance of multiple pregnancy, including twins, because it can stimulate more than one follicle to mature. Your doctor will monitor you with ultrasound.
A: Stop the medicine and contact your doctor immediately. Visual symptoms are a red flag and may mean the medicine needs to be changed.
A: No. This medicine is a prescription medicine and must only be taken under the supervision of a qualified clinician.
A: The number of cycles is decided by your doctor, and prolonged use without review is not recommended. Most specialists limit the number of cycles before considering other options.
🤔 Common Patient Concerns
🔄 Substitutes for clofert 25 tablet
View AllAlternative brands with exact same active ingredient:
-
fulfyl 25mg tabletMicro Labs Ltd ₹13.39 95.9% CHEAPER
-
enova 25mg tabletBsp Pharmaceuticals ₹21.25 93.5% CHEAPER
-
ferpill 25mg tabletIntas Pharmaceuticals Ltd ₹26.25 92% CHEAPER
-
Fertisafe 25mg TabletMediwin Pharmaceuticals ₹26.25 92% CHEAPER
-
clomisur 25mg tabletSurge Biotech Pvt Ltd ₹26.92 91.8% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine guarantees pregnancy.
Fact: This medicine can improve ovulation and the chance of conception, but it does not guarantee pregnancy, and many other factors affect fertility. - Myth: Taking a higher dose will make it work faster.
Fact: Higher doses do not always improve results and can increase the risk of ovarian hyperstimulation and multiple pregnancy. - Myth: This medicine is safe to take without any tests.
Fact: This medicine requires a proper fertility evaluation, liver tests, and ultrasound monitoring for safe use. - Myth: This medicine can be used to treat all types of infertility.
Fact: This medicine works mainly when ovulation is the problem, and it is not effective for blocked tubes or severe male factor infertility.
🔄 Alternative Options
Generic Alternatives
- Clomiphene 25 mg tablet
- Clomiphene 50 mg tablet
Brand Alternatives
- Clofert Max Tablet