anolet 2.5mg tablet - Letrozole (2.5mg) medicine

anolet 2.5mg tablet - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Maneesh Pharmaceuticals Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 28, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 28, 2026

What is anolet 2.5mg tablet used for?

Anolet (Letrozole) is used to treat ANTI NEOPLASTICS. It contains Letrozole (2.5mg), which Nonsteroidal aromatase inhibitor; inhibits conversion of androgens to estrogens. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Letrozole
  • Manufacturer: Maneesh Pharmaceuticals Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

๐Ÿ’Š anolet 2.5mg tablet Uses & Benefits

Adjuvant treatment of hormone receptor-positive early breast cancer; first-line treatment of advanced breast cancer in postmenopausal women

Off-label uses: Ovulation induction in infertility, endometriosis, male hypogonadism

๐Ÿ“‹ Drug Information

Generic Name(s)Letrozole
Brand NameAnolet
ManufacturerManeesh Pharmaceuticals Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI NEOPLASTICS
Action ClassAromatase inhibitor
Route of AdministrationOral
StorageStore at 20-25ยฐC (68-77ยฐF); protect from light and moisture
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed orally; bioavailability ~99.9%
DistributionWidely distributed; steady-state volume of distribution ~1.9 L/kg
Protein Binding~60% (primarily to albumin)
MetabolismHepatic via CYP3A4 and CYP2A6 to inactive metabolite
Half-Life~2 days (42 hours)
ExcretionRenal (90% as metabolites, <5% unchanged)
Bioavailability~99.9%
Onset of ActionWithin 24 hours
Peak Plasma Time~1-2 hours
Duration of ActionUp to 2-3 days

How It Works

Nonsteroidal aromatase inhibitor; inhibits conversion of androgens to estrogens

Mechanism Steps

1Letrozole binds to the heme group of aromatase (CYP19A1)
2Competitively inhibits the conversion of androstenedione to estrone and testosterone to estradiol
3Reduces estrogen levels in peripheral tissues and tumor microenvironment

๐Ÿ’ก How to Take anolet 2.5mg tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of anolet 2.5mg tablet

โœ… Common Side Effects

  • Hot flashes
  • Arthralgia
  • Fatigue
  • Nausea
  • Headache
  • Night sweats

๐Ÿšจ Serious Side Effects

  • Bone fractures
  • Osteoporosis
  • Cardiovascular events
  • Severe liver injury

โš ๏ธ Rare Side Effects

  • Stevens-Johnson syndrome
  • Angioedema
  • Interstitial pneumonitis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Tamoxifen Major Reduced letrozole plasma levels
Estrogen-containing therapies Major Antagonizes letrozole effect
CYP3A4 inhibitors (e.g., ketoconazole) Moderate Increased letrozole levels
CYP3A4 inducers (e.g., rifampin) Moderate Decreased letrozole levels
Warfarin Minor Possible increased INR
Cimetidine Minor Slight increase in letrozole levels

๐Ÿšจ Major Interactions

  • Tamoxifen
  • Estrogen-containing therapies

โšก Moderate Interactions

  • CYP3A4 inhibitors
  • CYP3A4 inducers

โ„น๏ธ Minor Interactions

  • Warfarin
  • Cimetidine

๐Ÿฝ๏ธ Food Interactions

No significant food interactions

๐Ÿท Alcohol Interaction

No known interaction

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Pregnancy, lactation, hypersensitivity, premenopausal women (unless part of specific protocol)

๐Ÿ“Š Monitoring Parameters

Liver function tests, lipid profile, bone density (long-term), pregnancy test (if applicable)

๐Ÿคฑ Lactation Safety

Not recommended; excreted in milk

๐Ÿ’Š Overdose Management

Symptomatic and supportive; no specific antidote

โฐ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose. Do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 28, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for anolet 2.5mg tablet

View All

Alternative brands with exact same active ingredient (Letrozole (2.5mg)):

Medical Note: Always consult your doctor before switching medications.

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