clobamet 10 tablet - Clobazam (10mg) medicine

clobamet 10 tablet - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Emocare ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 27, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 27, 2026

What is clobamet 10 tablet used for?

Adobe 10mg Tablet (Clobazam) is used to treat NEURO CNS. It contains Clobazam (10mg), which Binds to benzodiazepine site on GABA-A receptors, enhancing GABAergic inhibition. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Clobazam
  • Manufacturer: Emocare
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š clobamet 10 tablet Uses & Benefits

Adjunctive therapy for epilepsy (Lennox-Gastaut syndrome), anxiety disorders.

Off-label uses: Status epilepticus (IV formulation), catamenial epilepsy, panic disorder.

๐Ÿ“‹ Drug Information

Generic Name(s)Clobazam
Brand NameAdobe 10mg Tablet
ManufacturerEmocare
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassNEURO CNS
Action ClassBenzodiazepines
Route of AdministrationOral.
StorageStore at 20-25ยฐC (68-77ยฐF), protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after oral administration; peak plasma concentrations achieved within 1-4 hours.
DistributionWidely distributed; crosses blood-brain barrier; volume of distribution approximately 1 L/kg.
Protein BindingApproximately 80-90% bound to plasma proteins.
MetabolismExtensively metabolized in the liver via CYP3A4 to active metabolite N-desmethylclobazam.
Half-LifeClobazam: 36-42 hours; N-desmethylclobazam: 71-82 hours.
ExcretionPrimarily renal (87% as metabolites, 2% unchanged); fecal (11%).
BioavailabilityApproximately 90%.
Onset of Action30-60 minutes.
Peak Plasma Time1-4 hours.
Duration of Action12-24 hours.

How It Works

Binds to benzodiazepine site on GABA-A receptors, enhancing GABAergic inhibition.

Mechanism Steps

1Clobazam binds to benzodiazepine site on GABA-A receptor.
2Enhances affinity of GABA for receptor.
3Increases frequency of chloride channel opening.

๐Ÿ’ก How to Take clobamet 10 tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of clobamet 10 tablet

โœ… Common Side Effects

  • Drowsiness
  • Sedation
  • Dizziness
  • Ataxia
  • Fatigue

๐Ÿšจ Serious Side Effects

  • Respiratory depression
  • Paradoxical reactions (agitation, aggression)
  • Stevens-Johnson syndrome
  • Dependence/withdrawal seizures

โš ๏ธ Rare Side Effects

  • Blood dyscrasias
  • Hepatic failure
  • Angioedema

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Alcohol Major Increased sedation and respiratory depression
Opioids Major Additive CNS depression, risk of respiratory depression
Ketoconazole Major Increased clobazam levels due to CYP3A4 inhibition
Carbamazepine Major Decreased clobazam levels due to CYP3A4 induction

๐Ÿšจ Major Interactions

  • CNS depressants (e.g., alcohol, opioids)
  • CYP3A4 inhibitors (e.g., ketoconazole)
  • CYP3A4 inducers (e.g., carbamazepine)

โšก Moderate Interactions

  • Antihistamines
  • Antipsychotics
  • MAOIs

โ„น๏ธ Minor Interactions

  • Caffeine
  • Oral contraceptives

๐Ÿฝ๏ธ Food Interactions

Grapefruit juice may increase clobazam levels.

๐Ÿท Alcohol Interaction

Additive CNS depression; avoid concurrent use.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to benzodiazepines, severe hepatic impairment, narrow-angle glaucoma, myasthenia gravis, respiratory insufficiency.

๐Ÿ“Š Monitoring Parameters

Liver function tests, CBC, renal function, signs of CNS depression, tolerance/dependence.

๐Ÿคฑ Lactation Safety

Excreted in breast milk; use with caution; monitor infant for sedation.

๐Ÿ’Š Overdose Management

Supportive care; flumazenil as antidote (caution in mixed overdoses).

โฐ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose; do not double.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 27, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for clobamet 10 tablet

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Alternative brands with exact same active ingredient (Clobazam (10mg)):

Medical Note: Always consult your doctor before switching medications.

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