clivin 300mg injection - Clindamycin (300mg) medicine

clivin 300mg injection

4.5 (13 reviews)
๐Ÿญ Divine Savior Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 21, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 21, 2026

What is clivin 300mg injection used for?

Acnesol Gel (Clindamycin) is used to treat ANTI INFECTIVES. It contains Clindamycin (300mg), which Inhibits bacterial protein synthesis by binding to 50S ribosomal subunit, preven. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Clindamycin
  • Manufacturer: Divine Savior Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: B
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

๐Ÿ’Š clivin 300mg injection Uses & Benefits

Treatment of acne vulgaris.

Off-label uses: Bacterial vaginosis (topical), Perioral dermatitis

๐Ÿ“‹ Drug Information

Generic Name(s)Clindamycin
Brand NameAcnesol Gel
ManufacturerDivine Savior Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassLincosamides
Route of AdministrationTopical
StorageStore at 20-25ยฐC (68-77ยฐF); protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionApproximately 10% of topically applied clindamycin is absorbed systemically.
DistributionDistributes widely into body tissues and fluids, including bone, but not significantly into cerebrospinal fluid.
Protein BindingAbout 93-94% bound to plasma proteins.
MetabolismHepatic metabolism to active and inactive metabolites.
Half-LifeApproximately 2-3 hours (topical absorption minimal).
ExcretionPrimarily renal (10% unchanged, rest as metabolites) and biliary.
BioavailabilityLow systemic bioavailability after topical application (<10%).
Onset of ActionWithin a few days to weeks of regular application.
Peak Plasma TimeNot applicable for topical use; minimal systemic absorption.
Duration of ActionSustained antibacterial effect on skin for up to 12 hours.

How It Works

Inhibits bacterial protein synthesis by binding to 50S ribosomal subunit, preventing peptide bond formation.

Mechanism Steps

1Clindamycin binds to the 50S ribosomal subunit of bacteria.
2Inhibits peptide bond formation by blocking the peptidyl transferase activity.
3Prevents bacterial protein synthesis, leading to bacteriostatic effect.

๐Ÿ’ก How to Take clivin 300mg injection

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of clivin 300mg injection

โœ… Common Side Effects

  • Skin dryness
  • Peeling
  • Itching
  • Erythema
  • Burning sensation

๐Ÿšจ Serious Side Effects

  • Pseudomembranous colitis
  • Severe allergic reactions
  • Stevens-Johnson syndrome

โš ๏ธ Rare Side Effects

  • Contact dermatitis
  • Urticaria
  • Angioedema

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Erythromycin Major Antagonism of antibacterial effect
Neuromuscular blocking agents Major Enhanced neuromuscular blockade
Warfarin Moderate Increased INR and bleeding risk
Oral contraceptives Moderate Reduced contraceptive efficacy
Kaolin Minor Reduced absorption of clindamycin
Aluminum-containing antacids Minor Reduced absorption of clindamycin

๐Ÿšจ Major Interactions

  • Erythromycin
  • Neuromuscular blocking agents

โšก Moderate Interactions

  • Warfarin
  • Oral contraceptives

โ„น๏ธ Minor Interactions

  • Kaolin
  • Aluminum-containing antacids

๐Ÿฝ๏ธ Food Interactions

No significant food interactions.

๐Ÿท Alcohol Interaction

No known interaction.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to clindamycin or lincomycin; history of antibiotic-associated colitis.

๐Ÿ“Š Monitoring Parameters

Skin irritation, signs of superinfection, diarrhea.

๐Ÿคฑ Lactation Safety

Caution; not known if excreted in breast milk after topical use.

๐Ÿ’Š Overdose Management

Topical overdose unlikely; if ingested, symptomatic and supportive care.

โฐ Missed Dose

Apply as soon as remembered; skip if almost time for next dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 21, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for clivin 300mg injection

View All

Alternative brands with exact same active ingredient (Clindamycin (300mg)):

Medical Note: Always consult your doctor before switching medications.

โญ User Reviews

Verified User Jul 10, 2026

Effective and reliable. Worked as expected.

Happy Patient Jul 10, 2026

Effective and reliable. Worked as expected.

Verified User Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Trusted Reviewer Jul 10, 2026

Found this to be a helpful product. Good results.

Happy Patient Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

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