braclin 300mg capsule - Clindamycin (300mg) medicine

Aclina 300 Capsule (Clindamycin 300 mg): Complete Medicine Guide

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🏭 Plenus Pharmaceuticals Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 24, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established
Reviewed by
SaathiMed Expert Panel | Sep 24, 2026

When to Call Your Doctor IMMEDIATELY

  • Severe or bloody diarrhoea
  • Severe abdominal cramps
  • Rash, hives, or swelling of face, lips, or throat
  • Difficulty breathing or swallowing
  • Yellowing of skin or eyes
  • Dark urine or pale stools
  • Unusual bleeding or bruising
  • Severe headache with fever and neck stiffness

If experiencing severe symptoms, call emergency services immediately.

What is braclin 300mg capsule used for?

This medicine is a prescription antibiotic containing Clindamycin 300 mg. It treats serious bacterial infections of the skin, lungs, bones, joints, and teeth. It works by stopping bacteria from making proteins they need to survive. Take it exactly as prescribed and complete the full course.

  • Generic Name: Clindamycin (300mg)
  • Manufacturer: Plenus Pharmaceuticals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 braclin 300mg capsule के बारे में (Hindi Summary)

उपयोग: यह दवा क्लिंडामाइसिन 300 मिलीग्राम युक्त एक प्रिस्क्रिप्शन एंटीबायोटिक है। इसका उपयोग त्वचा, फेफड़ों, हड्डियों, जोड़ों और दांतों के गंभीर बैक्टीरियल संक्रमणों के इलाज के लिए किया जाता है। यह बैक्टीरिया के प्रोटीन संश्लेषण को रोककर उनकी वृद्धि को रोकती है। यह दवा पेनिसिलिन से एलर्जी वाले रोगियों के लिए भी उपयोगी है। इसे डॉक्टर के निर्देशानुसार पूरा कोर्स करें, भले ही आप बेहतर महसूस करें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, दस्त, पेट दर्द और मुंह में धातु जैसा स्वाद शामिल हैं। ये आमतौर पर हल्के होते हैं और अपने आप ठीक हो जाते हैं। गंभीर दुष्प्रभावों में गंभीर दस्त (जिसमें खून आ सकता है), एलर्जी प्रतिक्रियाएं, और यकृत की समस्याएं शामिल हैं। यदि आपको गंभीर या खूनी दस्त, त्वचा पर चकत्ते, सूजन, या सांस लेने में कठिनाई हो, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक न छोड़ें और कोर्स पूरा करें। कैप्सूल को पूरा निगलें और साथ में एक गिलास पानी पिएं। इसे भोजन के साथ या बिना भोजन के लिया जा सकता है, लेकिन भोजन के साथ लेने से पेट की जलन कम होती है। दवा लेने के बाद 30 मिनट तक लेटें नहीं। यदि आपको गंभीर या खूनी दस्त हो, तो दवा बंद करें और तुरंत डॉक्टर से मिलें। बिना डॉक्टर की सलाह के दस्त रोकने की दवा न लें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 braclin 300mg capsule Uses & Benefits

[{"condition":"Bacterial skin and soft tissue infections","description":"Treats infections such as cellulitis, abscesses, and wound infections caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Respiratory tract infections","description":"Used for lung infections including pneumonia and lung abscess, especially in patients allergic to penicillin.","evidence":"Well-established"},{"condition":"Bone and joint infections","description":"Effective against osteomyelitis and septic arthritis caused by susceptible organisms.","evidence":"Well-established"},{"condition":"Dental infections","description":"Prescribed for dental abscesses and periodontal infections.","evidence":"Well-established"},{"condition":"Pelvic inflammatory disease","description":"Used in combination with other antibiotics for pelvic inflammatory disease.","evidence":"Well-established"},{"condition":"Intra-abdominal infections","description":"Treats abdominal infections such as peritonitis and intra-abdominal abscesses.","evidence":"Well-established"},{"condition":"Bacterial vaginosis","description":"Used as an alternative treatment for bacterial vaginosis.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Malaria (in combination)","description":"Sometimes used off-label in combination with other antimalarials for resistant malaria.","evidence":"Limited"},{"condition":"Toxoplasmosis","description":"Used off-label in combination with pyrimethamine for toxoplasmic encephalitis in immunocompromised patients.","evidence":"Limited"},{"condition":"Pneumocystis pneumonia","description":"Occasionally used off-label as an alternative in patients intolerant to standard therapy.","evidence":"Limited"}]

Primary treatment for: Bacterial infections

Also treats: Skin infections, Respiratory tract infections, Bone and joint infections, Dental infections, Pelvic inflammatory disease, Intra-abdominal infections

📋 Drug Information

Generic Name(s)Clindamycin (300mg)
Brand Namebraclin 300mg capsule
ManufacturerPlenus Pharmaceuticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassLincosamides
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Keep away from direct sunlight and moisture. Do not refrigerate.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always prescribe this medicine only for confirmed or strongly suspected bacterial infections.
2
Advise patients to take the capsule with a full glass of water and remain upright for 30 minutes to prevent esophageal irritation.
3
Warn patients about the risk of severe diarrhoea and instruct them to stop the medicine and seek immediate medical help if it occurs.
4
Avoid concurrent use with erythromycin due to antagonism.
5
Monitor liver and kidney function in patients with pre-existing hepatic or renal impairment.
6
Consider alternative antibiotics in patients with a history of colitis.
7
Educate patients on the importance of completing the full course to prevent resistance.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Skin infection with redness and pus
This medicine is commonly prescribed for skin and soft tissue infections.
Likely Use
Dental abscess
This medicine is effective against dental infections.
Likely Use
Common cold
This medicine is not effective against viral infections.
Not Primary
Fever without bacterial infection
This medicine is not a primary fever reducer and should not be used without a bacterial infection diagnosis.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is rapidly and almost completely absorbed from the gastrointestinal tract after oral administration. The absorption is not significantly affected by food, but taking it with food may reduce stomach irritation. The bioavailability is approximately 90%.
DistributionThis medicine distributes widely into body tissues and fluids, including bone, synovial fluid, pleural fluid, and peritoneal fluid. It does not reach therapeutic concentrations in the cerebrospinal fluid even in the presence of inflamed meninges. It crosses the placenta and is excreted in breast milk.
Protein BindingApproximately 90% of this medicine is bound to plasma proteins, primarily albumin.
MetabolismThis medicine is extensively metabolized in the liver, primarily by the cytochrome P450 enzyme CYP3A4, to active and inactive metabolites. The major active metabolite is N-desmethylclindamycin, which retains some antibacterial activity.
Half-LifeThe elimination half-life of this medicine is approximately 2 to 3 hours in healthy adults. It may be prolonged in patients with severe liver disease or renal impairment.
ExcretionThis medicine and its metabolites are excreted primarily in the urine and faeces. About 10% of the dose is excreted unchanged in the urine, and the remainder is excreted as metabolites. The drug is also excreted in breast milk.
BioavailabilityThe oral bioavailability of this medicine is approximately 90%.
Onset of ActionThe onset of action of this medicine is typically within 1 to 2 hours after oral administration, but clinical improvement may take 24 to 48 hours.
Peak Plasma TimeThe peak plasma concentration of this medicine is reached approximately 1 to 2 hours after oral administration.
Duration of ActionThe duration of action of this medicine is generally about 6 to 8 hours, which supports dosing every 6 to 8 hours.

How It Works

This medicine works by binding to the 50S ribosomal subunit of susceptible bacteria, specifically to the 23S rRNA component. This binding inhibits the early steps of protein synthesis by preventing the formation of peptide bonds and causing premature dissociation of the peptidyl-tRNA from the ribosome. As a result, the bacteria cannot produce essential proteins and cannot multiply, leading to their death or inhibition of growth. This medicine is primarily bacteriostatic but can be bactericidal at higher concentrations against some organisms.

Mechanism Steps

1
Binding to the 50S ribosomal subunit: This medicine binds specifically to the 23S rRNA component of the bacterial 50S ribosomal subunit.
2
Inhibition of peptide bond formation: The binding interferes with the transpeptidation reaction, preventing the formation of peptide bonds between amino acids.
3
Premature dissociation of peptidyl-tRNA: This medicine causes the peptidyl-tRNA to dissociate from the ribosome before the protein chain is complete.
4
Inhibition of protein synthesis: As a result, the bacteria cannot synthesize essential proteins required for growth and replication.
5
Bacterial growth inhibition or death: The interruption of protein synthesis leads to inhibition of bacterial growth (bacteriostatic) or death (bactericidal) depending on the organism and drug concentration.

💡 How to Take braclin 300mg capsule

Strength: Capsule, 300 mg

1Take this medicine exactly as prescribed by your doctor.
2Swallow the capsule whole with a full glass of water.
3Do not crush, chew, or open the capsule.
4You may take it with or without food, but taking it with food may reduce stomach upset.
5Stay upright for at least 30 minutes after taking the capsule to prevent esophageal irritation.
6Complete the full course of treatment even if you feel better.
7Do not share this medicine with others.

Dosage Information

Adult DosageThe usual adult dose of this medicine for most infections is 150 mg to 300 mg every 6 hours, or 300 mg to 450 mg every 8 hours, depending on the severity of the infection. For severe infections, doses up to 450 mg every 6 hours may be used. The dose must be individualized by a qualified clinician based on the indication, age, weight, renal and hepatic function. Always follow your doctor's prescription exactly.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine, especially gastrointestinal side effects. Dose adjustment may be needed based on renal and hepatic function. Consult your doctor for appropriate dosing.
Renal ImpairmentIn patients with severe renal impairment, dose adjustment may be necessary. The dose must be individualized by a qualified clinician based on renal function.
Hepatic ImpairmentIn patients with severe hepatic impairment, dose adjustment may be necessary. The dose must be individualized by a qualified clinician based on hepatic function.
Maximum Daily DoseThe maximum recommended daily dose is 1800 mg for adults, but this must be individualized by a qualified clinician.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset and nausea.
Grapefruit juice
Avoid
May increase drug levels by inhibiting CYP3A4.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of braclin 300mg capsule

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food to reduce nausea. If it persists, consult your doctor.
Vomiting (Common (5-10%))
Stay hydrated with small sips of water. If vomiting is severe, contact your doctor.
Diarrhoea (Common (5-10%))
Drink plenty of fluids. If diarrhoea is severe or bloody, stop the medicine and seek medical help immediately.
Stomach pain (Common (5-10%))
Take with food. If pain is severe or persistent, consult your doctor.
Metallic taste (Common (5-10%))
This usually resolves on its own. Chewing sugar-free gum may help.

🚨 Serious Side Effects

Clindamycin-associated colitis (severe diarrhoea) (Uncommon (0.1-1%))
Stop the medicine and seek immediate medical attention if you develop severe, persistent, or bloody diarrhoea.
Severe allergic reactions (anaphylaxis) (Rare (<0.1%))
Seek emergency medical help if you experience rash, swelling of face or throat, difficulty breathing, or dizziness.
Liver toxicity (Rare (<0.1%))
Report yellowing of skin or eyes, dark urine, or severe abdominal pain to your doctor immediately.
Blood disorders (e.g., neutropenia, thrombocytopenia) (Rare (<0.1%))
Inform your doctor if you notice unusual bruising, bleeding, or signs of infection.

⚠️ Rare Side Effects

Esophageal ulceration
Take the capsule with a full glass of water and remain upright for 30 minutes. Report chest pain or difficulty swallowing.
Polyarthritis
Consult a doctor if you develop joint pain or swelling.
Stevens-Johnson syndrome
Seek immediate medical attention if you develop a severe rash with blistering or peeling skin.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Moderate
Erythromycin Major
Neuromuscular blockers Major
Kaolin-pectin Major
CYP3A4 inhibitors Moderate
CYP3A4 inducers Moderate
Oral contraceptives Minor
Cyclosporine Minor
Alcohol Moderate

🚨 Major Interactions

  • Neuromuscular blocking agents (e.g., vecuronium, pancuronium)
  • Erythromycin
  • Kaolin-pectin antidiarrhoeal

⚡ Moderate Interactions

  • CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, ritonavir)
  • CYP3A4 inducers (e.g., rifampicin, carbamazepine, phenytoin)
  • Warfarin

🍷 Alcohol Interaction

Alcohol may worsen stomach irritation and increase the risk of gastrointestinal side effects such as nausea and vomiting. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to Clindamycin or other lincosamide antibiotics","History of severe diarrhoea or colitis associated with antibiotic use","Not for use in patients with meningitis (inadequate CSF penetration)"]

⚠️ Warnings & Precautions

["This medicine can cause severe diarrhoea (Clindamycin-associated colitis). Stop the medicine and seek medical help if diarrhoea becomes severe or bloody.","Do not use anti-diarrhoeal medicines without consulting your doctor, as they may worsen colitis.","Use with caution in patients with liver disease; monitor liver function.","Use with caution in patients with kidney disease; dose adjustment may be needed.","This medicine may cause allergic reactions; seek immediate help if you experience rash, swelling, or difficulty breathing.","Prolonged use may lead to overgrowth of non-susceptible organisms, including fungi.","This medicine should not be used for viral infections such as the common cold.","Take with a full glass of water to prevent esophageal irritation."]

🤱 Lactation Safety

This medicine is excreted in breast milk and may cause diarrhoea or bloody stools in the nursing infant. It is not recommended during breastfeeding unless the potential benefit outweighs the risk. If used, monitor the infant for diarrhoea or thrush.

💊 Overdose Management

Overdose of this medicine may cause severe gastrointestinal symptoms such as nausea, vomiting, and diarrhoea. There is no specific antidote. Treatment is supportive and symptomatic. In case of overdose, seek immediate medical attention. Haemodialysis and peritoneal dialysis are not effective in removing this medicine from the blood.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop early, even if you feel better. Swallow the capsule whole with a full glass of water to avoid throat irritation. You can take it with or without food, but taking it with food may reduce stomach upset. Avoid lying down for at least 30 minutes after taking the capsule. Do not share this medicine with others. Inform your doctor if you have kidney or liver problems, or if you have ever had colitis or severe diarrhoea after taking antibiotics. If you develop severe or bloody diarrhoea, stop the medicine and seek medical help immediately. Do not use anti-diarrhoeal medicines without consulting your doctor, as they may worsen the condition. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more susceptible to gastrointestinal side effects and should be monitored closely. Dose adjustment may be needed based on renal and hepatic function. Ensure adequate hydration.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before taking this medicine. It is classified as Pregnancy Category B and should be used only if clearly needed. Discuss the risks and benefits with your healthcare provider.

🏥 Post-Surgery Considerations

This medicine may be prescribed after surgery to prevent or treat surgical site infections. Follow your surgeon's instructions carefully. Inform your surgeon if you have any allergies or history of colitis.

🦷 Dental Procedures

This medicine is often prescribed for dental infections. Inform your dentist if you are taking this medicine or have any allergies. It may be used before or after dental procedures to prevent infection.

💚 Lifestyle Tips for Better Results

🏃
Complete the full course of antibiotics as prescribed.
🥗
Stay well hydrated to help your body fight the infection.
😴
Get plenty of rest to support your immune system.
💧
Eat a balanced diet rich in fruits and vegetables.
🧘
Practice good hygiene to prevent the spread of infection.
🌞
Avoid sharing personal items like towels or utensils during an active infection.

🏋️ Exercise Considerations

You can continue light exercise if you feel well, but avoid strenuous activities if you have fever, fatigue, or severe infection symptoms. Listen to your body and rest when needed.

🥗 Diet Recommendations

Include probiotic-rich foods like yogurt to help maintain healthy gut flora.
Stay well hydrated with water and clear fluids.
Eat light, easily digestible meals if you have nausea.
Avoid spicy and greasy foods that may worsen stomach upset.
Include fruits and vegetables rich in vitamins to support recovery.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or fatigue in some people. Avoid driving or operating heavy machinery if you feel dizzy or unwell. Most people can continue their normal daily activities, but take rest as needed.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. Complete the full prescribed course even if you feel better. If you experience severe side effects such as bloody diarrhoea, severe allergic reactions, or signs of liver problems, stop the medicine and seek immediate medical attention.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to overgrowth of non-susceptible organisms, including fungi, and may increase the risk of antibiotic resistance. Prolonged use may also cause liver toxicity and blood disorders. Regular monitoring of liver function, kidney function, and blood counts may be required if used for extended periods. It should only be used for as long as necessary.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Probiotics

Can help prevent antibiotic-associated diarrhoea when taken alongside antibiotics.

Evidence: Moderate
Good hygiene

Prevents the spread of infection and supports recovery.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine may reduce the effectiveness of live bacterial vaccines (e.g., typhoid vaccine) if taken concurrently. Avoid live bacterial vaccines during treatment and for several days after. Consult your doctor for specific advice.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When travelling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your hand luggage to avoid loss or exposure to extreme temperatures. Store at room temperature and avoid direct sunlight. If crossing time zones, adjust your dosing schedule gradually, but consult your doctor for specific advice. Check customs regulations for carrying prescription medicines in your destination country.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with a dental abscess
He was prescribed this medicine for a painful tooth infection. He took it with food as advised and completed the 7-day course. His pain and swelling improved within 3 days, and the infection cleared completely. He was advised to follow up with a dentist for definitive treatment.
💡 Lesson: Taking this medicine with food reduces stomach upset, and completing the full course ensures the infection is fully treated.
👤 A 50-year-old woman with a skin infection after a minor injury
She developed redness and pus at the wound site. Her doctor prescribed this medicine. She experienced mild nausea initially but it subsided after taking it with meals. The infection resolved within a week. She was reminded not to stop the medicine early.
💡 Lesson: Mild side effects like nausea can be managed by taking the medicine with food, and it is crucial to complete the prescribed course.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling better within 24 to 48 hours, but it is important to complete the full course as prescribed.

Q: Can I take it with food?

A: Yes, you can take it with or without food. Taking it with food may help reduce stomach upset.

Q: What if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Q: Is it safe during pregnancy?

A: It is classified as Pregnancy Category B. It should be used during pregnancy only if clearly needed. Consult your doctor.

Q: Can I drink alcohol while taking this medicine?

A: It is advisable to avoid alcohol as it may worsen stomach side effects.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for braclin 300mg capsule

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure viral infections like the common cold.
    Fact: This medicine is an antibiotic and only works against bacterial infections. It is not effective against viruses.
  • Myth: You can stop taking this medicine as soon as you feel better.
    Fact: You must complete the full course as prescribed, even if you feel better, to prevent the infection from returning and to avoid antibiotic resistance.
  • Myth: This medicine is safe to take without a prescription.
    Fact: This medicine is a prescription antibiotic and should only be taken under a doctor's supervision.

🔄 Alternative Options

Generic Alternatives

  • Clindamycin 300 mg capsule

Brand Alternatives

  • Dalacin C 300 mg capsule
  • Clindac A 300 mg capsule
  • Clinmiskin 300 mg capsule

📊 Comparison with Similar Medicines

[{"medicine":"Clindamycin","class":"Lincosamide","spectrum":"Gram-positive and anaerobic bacteria","route":"Oral, topical, injection"},{"medicine":"Azithromycin","class":"Macrolide","spectrum":"Gram-positive, Gram-negative, atypical","route":"Oral, injection"},{"medicine":"Erythromycin","class":"Macrolide","spectrum":"Gram-positive, atypical","route":"Oral, topical, injection"},{"medicine":"Metronidazole","class":"Nitroimidazole","spectrum":"Anaerobic bacteria, protozoa","route":"Oral, topical, injection"}]

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