clazmet 80mg/500mg tablet
What is clazmet 80mg/500mg tablet used for?
Azukon-M Tablet (Gliclazide + Metformin) is used to treat ANTI DIABETIC. It contains Gliclazide (80mg) + Metformin (500mg), which Gliclazide stimulates insulin secretion from pancreatic beta cells; Metformin de. Always consult your doctor before use. Take as prescribed.
- Generic Name: Gliclazide + Metformin
- Manufacturer: Sentinel Remedies
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ clazmet 80mg/500mg tablet Uses & Benefits
Type 2 diabetes mellitus not controlled by monotherapy
Off-label uses: Polycystic ovary syndrome (metformin component)
๐ Drug Information
| Generic Name(s) | Gliclazide + Metformin |
| Brand Name | Azukon-M Tablet |
| Manufacturer | Sentinel Remedies |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI DIABETIC |
| Action Class | Sulfonylurea + Biguanide |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Gliclazide stimulates insulin secretion from pancreatic beta cells; Metformin decreases hepatic glucose production and increases insulin sensitivity
Mechanism Steps
๐ก How to Take clazmet 80mg/500mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of clazmet 80mg/500mg tablet
โ Common Side Effects
- Hypoglycemia
- Gastrointestinal upset
- Nausea
- Diarrhea
- Weight gain
๐จ Serious Side Effects
- Lactic acidosis
- Severe hypoglycemia
- Hepatic injury
โ ๏ธ Rare Side Effects
- Aplastic anemia
- Agranulocytosis
- Hemolytic anemia
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Miconazole | Major | Enhanced hypoglycemic effect |
| Phenylbutazone | Major | Increased sulfonylurea effect |
| ACE inhibitors | Moderate | Enhanced hypoglycemic effect |
| Beta-blockers | Moderate | Mask hypoglycemia symptoms |
| Corticosteroids | Moderate | Hyperglycemic effect |
| Cimetidine | Minor | Reduced metformin clearance |
| Ranitidine | Minor | Reduced metformin clearance |
๐จ Major Interactions
- Warfarin
- Miconazole
- Phenylbutazone
โก Moderate Interactions
- ACE inhibitors
- Beta-blockers
- Corticosteroids
โน๏ธ Minor Interactions
- Cimetidine
- Ranitidine
๐ฝ๏ธ Food Interactions
Food delays absorption of gliclazide; Metformin absorption reduced by food
๐ท Alcohol Interaction
Increased risk of lactic acidosis with metformin; may enhance hypoglycemic effect
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Renal impairment (eGFR <45 mL/min), hepatic impairment, diabetic ketoacidosis, hypersensitivity
๐ Monitoring Parameters
Blood glucose, HbA1c, renal function, liver function
๐คฑ Lactation Safety
Not recommended; metformin excreted in milk, gliclazide unknown
๐ Overdose Management
Monitor blood glucose; treat hypoglycemia with oral glucose; lactic acidosis requires hemodialysis
โฐ Missed Dose
Take as soon as remembered unless near next dose; do not double dose
๐จโโ๏ธ Reviewed by Expert
โญ User Reviews
Effective and reliable. Worked as expected.
Effective and reliable. Worked as expected.
Helpful and effective medicine as per my experience. Always consult a doctor.
Found this to be a helpful product. Good results.
Helpful and effective medicine as per my experience. Always consult a doctor.