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citopam 40 mg tablet

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Citalopram (40mg)

🏭 Sun Pharmaceutical Industries Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Jul 5, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Jul 05, 2026

What is citopam 40 mg tablet used for?

Citopam 20 Tablet (Citalopram) is used to treat NEURO CNS. It contains Citalopram (40mg), which Selective serotonin reuptake inhibitor (SSRI); increases serotonin levels in the. Always consult your doctor before use. Take as prescribed.

Generic Name: Citalopram
Manufacturer: Sun Pharmaceutical Industries Ltd
Form: Allopathy
Pregnancy Category: C
Prescription Required: Yes

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💊 citopam 40 mg tablet Uses & Benefits

Major depressive disorder; generalized anxiety disorder; obsessive-compulsive disorder; panic disorder; social anxiety disorder; post-traumatic stress disorder; premenstrual dysphoric disorder.

Off-label uses: Premature ejaculation; hot flashes; diabetic neuropathy; fibromyalgia; chronic pain; migraine prophylaxis.

📋 Drug Information

Generic Name(s)	Citalopram
Brand Name	Citopam 20 Tablet
Manufacturer	Sun Pharmaceutical Industries Ltd
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	NEURO CNS
Action Class	Selective Seretonin Reuptake inhibitors (SSRIs)
Route of Administration	Oral
Storage	Store at 20-25°C (68-77°F); protect from light and moisture.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed from the gastrointestinal tract; peak plasma concentration reached in 2-4 hours.

DistributionDistributed throughout the body; volume of distribution approximately 12 L/kg.

Protein BindingApproximately 80% bound to plasma proteins.

MetabolismHepatic metabolism via CYP3A4 and CYP2C19 to active metabolites (demethylcitalopram, didemethylcitalopram).

Half-LifeApproximately 35 hours (range 24-48 hours).

ExcretionPrimarily renal (about 75% as metabolites, 10% as unchanged drug); also fecal.

BioavailabilityApproximately 80%.

Onset of Action1-2 weeks for therapeutic effect; may take 4-6 weeks for full effect.

Peak Plasma Time2-4 hours after oral administration.

Duration of Action24 hours (once-daily dosing).

How It Works

Selective serotonin reuptake inhibitor (SSRI); increases serotonin levels in the synaptic cleft by blocking its reuptake into presynaptic neurons.

Mechanism Steps

1Citalopram binds to the serotonin transporter (SERT) on presynaptic neurons.

2Inhibition of serotonin reuptake into presynaptic neurons.

3Increased serotonin concentration in the synaptic cleft.

💡 How to Take citopam 40 mg tablet

Follow your doctor's prescription exactly.

⚠️ Side Effects of citopam 40 mg tablet

✅ Common Side Effects

Nausea
Dry mouth
Somnolence
Insomnia
Sweating
Fatigue
Dizziness
Diarrhea
Constipation
Sexual dysfunction (delayed ejaculation, anorgasmia, decreased libido)

🚨 Serious Side Effects

Serotonin syndrome
QT prolongation
Torsades de pointes
Seizures
Suicidal thoughts/behavior
Hyponatremia
Bleeding abnormalities
Angle-closure glaucoma

⚠️ Rare Side Effects

Hepatotoxicity
Pancreatitis
Agranulocytosis
Leukopenia
Thrombocytopenia
Allergic reactions (angioedema, urticaria)
Galactorrhea
Priapism

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
MAOIs	Major	Risk of serotonin syndrome (hyperthermia, rigidity, myoclonus, autonomic instability)
Linezolid	Major	Increased risk of serotonin syndrome
Methylene Blue	Major	Increased risk of serotonin syndrome
Pimozide	Major	QT prolongation risk
Triptans	Major	Additive serotonergic effects; risk of serotonin syndrome
Tramadol	Major	Additive serotonergic effects; risk of serotonin syndrome
St. John's Wort	Major	Additive serotonergic effects; risk of serotonin syndrome
Cimetidine	Moderate	Increased citalopram levels
Omeprazole	Moderate	Increased citalopram levels (CYP2C19 inhibition)
Ketoconazole	Moderate	Increased citalopram levels (CYP3A4 inhibition)
Lithium	Moderate	Increased serotonergic effects; risk of serotonin syndrome
Warfarin	Moderate	Increased bleeding risk
NSAIDs	Moderate	Increased bleeding risk
Aspirin	Moderate	Increased bleeding risk
Carbamazepine	Minor	Decreased citalopram levels (CYP3A4 induction)

🚨 Major Interactions

MAOIs
Linezolid
Methylene Blue
Pimozide
Other serotonergic drugs (e.g., triptans, tramadol, St. John's Wort)

⚡ Moderate Interactions

Cimetidine
CYP2C19 inhibitors (e.g., omeprazole)
CYP3A4 inhibitors (e.g., ketoconazole)
Lithium
Warfarin
NSAIDs
Aspirin

ℹ️ Minor Interactions

CYP2D6 substrates
CYP3A4 inducers (e.g., carbamazepine)

🍽️ Food Interactions

No significant food interactions; may be taken with or without food.

🍷 Alcohol Interaction

Avoid alcohol; may increase CNS depression and impair judgment.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to citalopram or any component; concurrent use with MAOIs or within 14 days of MAOI discontinuation; concurrent use with pimozide; known QT prolongation or congenital long QT syndrome; uncorrected hypokalemia or hypomagnesemia.

📊 Monitoring Parameters

Mental status (suicidal ideation, mood changes); ECG for QT interval; electrolytes (potassium, magnesium); liver function tests; renal function; signs of serotonin syndrome; bleeding risk.

🤱 Lactation Safety

Citalopram is excreted in breast milk; use with caution, monitor infant for drowsiness, poor feeding

💊 Overdose Management

Activated charcoal if recent ingestion; supportive care; monitor ECG for QT prolongation; consider benzodiazepines for seizures; serotonin syndrome management (cyproheptadine, supportive care).

⏰ Missed Dose

Take as soon as remembered unless close to next dose; do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Jul 05, 2026

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🔄 Substitutes for citopam 40 mg tablet

View All

Alternative brands with exact same active ingredient (Citalopram (40mg)):

Medical Note: Always consult your doctor before switching medications.

😊 Was this information helpful?

📌 Quick Facts

Storage	Store at 20-25°C (68-77°F); protect from light and moisture.
Route	Oral
Pregnancy	Category C
Breastfeeding	Citalopram is excreted in breast milk; use with caution, monitor infant for drowsiness, poor feeding
Alcohol	Avoid alcohol; may increase CNS depression and impair judgment.
Onset of Action	1-2 weeks for therapeutic effect; may take 4-6 weeks for full effect.
Half-Life	Approximately 35 hours (range 24-48 hours).
Prescription	✅ Required

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