celimine 40mg tablet - Citalopram (40mg) medicine

celimine 40mg tablet - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Ryon Pharma ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 29, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 29, 2026

What is celimine 40mg tablet used for?

Citopam 20 Tablet (Citalopram) is used to treat NEURO CNS. It contains Citalopram (40mg), which Selective serotonin reuptake inhibitor (SSRI); increases serotonin levels in the. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Citalopram
  • Manufacturer: Ryon Pharma
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

๐Ÿ’Š celimine 40mg tablet Uses & Benefits

Major depressive disorder; generalized anxiety disorder; obsessive-compulsive disorder; panic disorder; social anxiety disorder; post-traumatic stress disorder; premenstrual dysphoric disorder.

Off-label uses: Premature ejaculation; hot flashes; diabetic neuropathy; fibromyalgia; chronic pain; migraine prophylaxis.

๐Ÿ“‹ Drug Information

Generic Name(s)Citalopram
Brand NameCitopam 20 Tablet
ManufacturerRyon Pharma
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassNEURO CNS
Action ClassSelective Seretonin Reuptake inhibitors (SSRIs)
Route of AdministrationOral
StorageStore at 20-25ยฐC (68-77ยฐF); protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed from the gastrointestinal tract; peak plasma concentration reached in 2-4 hours.
DistributionDistributed throughout the body; volume of distribution approximately 12 L/kg.
Protein BindingApproximately 80% bound to plasma proteins.
MetabolismHepatic metabolism via CYP3A4 and CYP2C19 to active metabolites (demethylcitalopram, didemethylcitalopram).
Half-LifeApproximately 35 hours (range 24-48 hours).
ExcretionPrimarily renal (about 75% as metabolites, 10% as unchanged drug); also fecal.
BioavailabilityApproximately 80%.
Onset of Action1-2 weeks for therapeutic effect; may take 4-6 weeks for full effect.
Peak Plasma Time2-4 hours after oral administration.
Duration of Action24 hours (once-daily dosing).

How It Works

Selective serotonin reuptake inhibitor (SSRI); increases serotonin levels in the synaptic cleft by blocking its reuptake into presynaptic neurons.

Mechanism Steps

1Citalopram binds to the serotonin transporter (SERT) on presynaptic neurons.
2Inhibition of serotonin reuptake into presynaptic neurons.
3Increased serotonin concentration in the synaptic cleft.

๐Ÿ’ก How to Take celimine 40mg tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of celimine 40mg tablet

โœ… Common Side Effects

  • Nausea
  • Dry mouth
  • Somnolence
  • Insomnia
  • Sweating
  • Fatigue
  • Dizziness
  • Diarrhea
  • Constipation
  • Sexual dysfunction (delayed ejaculation, anorgasmia, decreased libido)

๐Ÿšจ Serious Side Effects

  • Serotonin syndrome
  • QT prolongation
  • Torsades de pointes
  • Seizures
  • Suicidal thoughts/behavior
  • Hyponatremia
  • Bleeding abnormalities
  • Angle-closure glaucoma

โš ๏ธ Rare Side Effects

  • Hepatotoxicity
  • Pancreatitis
  • Agranulocytosis
  • Leukopenia
  • Thrombocytopenia
  • Allergic reactions (angioedema, urticaria)
  • Galactorrhea
  • Priapism

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
MAOIs Major Risk of serotonin syndrome (hyperthermia, rigidity, myoclonus, autonomic instability)
Linezolid Major Increased risk of serotonin syndrome
Methylene Blue Major Increased risk of serotonin syndrome
Pimozide Major QT prolongation risk
Triptans Major Additive serotonergic effects; risk of serotonin syndrome
Tramadol Major Additive serotonergic effects; risk of serotonin syndrome
St. John's Wort Major Additive serotonergic effects; risk of serotonin syndrome
Cimetidine Moderate Increased citalopram levels
Omeprazole Moderate Increased citalopram levels (CYP2C19 inhibition)
Ketoconazole Moderate Increased citalopram levels (CYP3A4 inhibition)
Lithium Moderate Increased serotonergic effects; risk of serotonin syndrome
Warfarin Moderate Increased bleeding risk
NSAIDs Moderate Increased bleeding risk
Aspirin Moderate Increased bleeding risk
Carbamazepine Minor Decreased citalopram levels (CYP3A4 induction)

๐Ÿšจ Major Interactions

  • MAOIs
  • Linezolid
  • Methylene Blue
  • Pimozide
  • Other serotonergic drugs (e.g., triptans, tramadol, St. John's Wort)

โšก Moderate Interactions

  • Cimetidine
  • CYP2C19 inhibitors (e.g., omeprazole)
  • CYP3A4 inhibitors (e.g., ketoconazole)
  • Lithium
  • Warfarin
  • NSAIDs
  • Aspirin

โ„น๏ธ Minor Interactions

  • CYP2D6 substrates
  • CYP3A4 inducers (e.g., carbamazepine)

๐Ÿฝ๏ธ Food Interactions

No significant food interactions; may be taken with or without food.

๐Ÿท Alcohol Interaction

Avoid alcohol; may increase CNS depression and impair judgment.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to citalopram or any component; concurrent use with MAOIs or within 14 days of MAOI discontinuation; concurrent use with pimozide; known QT prolongation or congenital long QT syndrome; uncorrected hypokalemia or hypomagnesemia.

๐Ÿ“Š Monitoring Parameters

Mental status (suicidal ideation, mood changes); ECG for QT interval; electrolytes (potassium, magnesium); liver function tests; renal function; signs of serotonin syndrome; bleeding risk.

๐Ÿคฑ Lactation Safety

Citalopram is excreted in breast milk; use with caution, monitor infant for drowsiness, poor feeding

๐Ÿ’Š Overdose Management

Activated charcoal if recent ingestion; supportive care; monitor ECG for QT prolongation; consider benzodiazepines for seizures; serotonin syndrome management (cyproheptadine, supportive care).

โฐ Missed Dose

Take as soon as remembered unless close to next dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 29, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for celimine 40mg tablet

View All

Alternative brands with exact same active ingredient (Citalopram (40mg)):

Medical Note: Always consult your doctor before switching medications.

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