citafine 200mg injection - Uses, Price, Side Effects & Substitutes
What is citafine 200mg injection used for?
Abigem 200mg Injection (Gemcitabine) is used to treat ANTI NEOPLASTICS. It contains Gemcitabine (200mg), which Gemcitabine is a nucleoside analog that inhibits DNA synthesis by incorporating . Always consult your doctor before use. Take as prescribed.
- Generic Name: Gemcitabine
- Manufacturer: Emcure Pharmaceuticals Ltd
- Form: Allopathy
- Pregnancy Category: D
- Prescription Required: Yes
๐ citafine 200mg injection Uses & Benefits
Non-small cell lung cancer, pancreatic cancer, bladder cancer, breast cancer, ovarian cancer.
Off-label uses: Hepatocellular carcinoma, lymphoma, sarcoma.
๐ Drug Information
| Generic Name(s) | Gemcitabine |
| Brand Name | Abigem 200mg Injection |
| Manufacturer | Emcure Pharmaceuticals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | Antimetabolites |
| Route of Administration | Intravenous infusion |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from light. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Gemcitabine is a nucleoside analog that inhibits DNA synthesis by incorporating into DNA and inhibiting ribonucleotide reductase.
Mechanism Steps
๐ก How to Take citafine 200mg injection
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of citafine 200mg injection
โ Common Side Effects
- Nausea
- Vomiting
- Fatigue
- Fever
- Myelosuppression
- Alopecia
๐จ Serious Side Effects
- Severe myelosuppression
- Pulmonary toxicity
- Hemolytic uremic syndrome
- Hepatotoxicity
โ ๏ธ Rare Side Effects
- Capillary leak syndrome
- Posterior reversible encephalopathy syndrome
- Cardiotoxicity
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased INR and bleeding risk |
| Live vaccines | Major | Risk of disseminated infection |
| Bleomycin | Major | Increased pulmonary toxicity |
| Methotrexate | Moderate | Increased toxicity |
| Cisplatin | Moderate | Enhanced myelosuppression |
| Radiation therapy | Moderate | Increased radiation toxicity |
| Acetaminophen | Minor | Possible hepatotoxicity |
| Digoxin | Minor | Decreased digoxin levels |
๐จ Major Interactions
- Warfarin
- Live vaccines
- Bleomycin
โก Moderate Interactions
- Methotrexate
- Cisplatin
- Radiation therapy
โน๏ธ Minor Interactions
- Acetaminophen
- Digoxin
๐ฝ๏ธ Food Interactions
No significant food interactions.
๐ท Alcohol Interaction
Avoid alcohol due to increased hepatotoxicity risk.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to gemcitabine, severe bone marrow suppression, pregnancy.
๐ Monitoring Parameters
Complete blood count, liver function tests, renal function, pulmonary function.
๐คฑ Lactation Safety
Contraindicated; excreted in breast milk.
๐ Overdose Management
Supportive care; no specific antidote. Monitor for myelosuppression.
โฐ Missed Dose
Administer as soon as possible; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for citafine 200mg injection
View AllAlternative brands with exact same active ingredient (Gemcitabine (200mg)):
-
gemchem 200mg injectionNeon Laboratories Ltd โน439.20 72.6% CHEAPER
-
gemce fil 200mg injectionFourrts India Laboratories Pvt Ltd โน445.31 72.2% CHEAPER
-
gembin 200mg injectionBiochem Pharmaceutical Industries โน765.10 52.2% CHEAPER
-
gembine 200mg injectionZydus Cadila โน799.60 50.1% CHEAPER
-
gemacta 200mg injectionMacleods Pharmaceuticals Pvt Ltd โน865.37 45.9% CHEAPER
-
mygem 200mg powder for injectionMylan Pharmaceuticals Pvt Ltd โน932.00 41.8% CHEAPER
-
xtroz 200mg injectionSun Pharmaceutical Industries Ltd โน987.50 38.3% CHEAPER
-
gemtero 200 mg injectionHetero Drugs Ltd โน1,041.56 34.9% CHEAPER
-
uvgem 200mg injectionU & V Cancure Pvt. Ltd. โน1,073.38 33% CHEAPER
-
gemfect 200mg injectionAureate Healthcare Pvt Ltd โน1,096.88 31.5% CHEAPER
Medical Note: Always consult your doctor before switching medications.