Cisplatin 50mg Injection: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Fever, chills, or signs of infection
- Unusual bleeding or bruising
- Reduced urine output or swelling
- Difficulty hearing or ringing in the ears
- Numbness, tingling, or weakness in hands or feet
- Severe nausea and vomiting that does not stop
- Chest pain, shortness of breath, or palpitations
- Sudden swelling of face, lips, or throat
- Severe headache with confusion or vision changes
- Yellowing of skin or eyes
If experiencing severe symptoms, call emergency services immediately.
What is cisget 50mg injection used for?
This medicine is a platinum-based chemotherapy drug given intravenously to treat several types of cancer, including testicular, ovarian, bladder, lung, and head and neck cancers. It works by damaging DNA in cancer cells and stopping them from dividing. It is given only by a healthcare professional in a hospital or cancer centre, with close monitoring for kidney, hearing, and nerve side effects.
- Generic Name: Cisplatin
- Manufacturer: Getwell Pharmaceutical Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 cisget 50mg injection के बारे में (Hindi Summary)
उपयोग: यह दवा एक कीमोथेरेपी दवा है जिसे सिस्प्लाटिन कहा जाता है। यह इंजेक्शन के रूप में नस के माध्यम से दी जाती है और कई प्रकार के कैंसर के इलाज में उपयोग की जाती है, जैसे अंडकोष का कैंसर, अंडाशय का कैंसर, मूत्राशय का कैंसर, फेफड़ों का कैंसर और सिर तथा गर्दन का कैंसर। यह कैंसर कोशिकाओं के डीएनए को नुकसान पहुंचाकर उन्हें बढ़ने और विभाजित होने से रोकती है। यह दवा केवल अस्पताल या कैंसर केंद्र में योग्य डॉक्टर या नर्स द्वारा दी जाती है। इसे घर पर स्वयं नहीं लगाया जा सकता। इलाज के दौरान गुर्दे, सुनने की क्षमता और रक्त की नियमित जांच की जाती है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, भूख न लगना, दस्त, मुंह में छाले, थकान और रक्त कोशिकाओं की कमी शामिल हैं। कुछ लोगों को कान में आवाज सुनाई देती है या सुनने में कठिनाई होती है, हाथ-पैरों में झुनझुनी या सुन्नपन होता है। गंभीर दुष्प्रभावों में गुर्दे की क्षति, गंभीर संक्रमण, सुनने की क्षमता में कमी, तंत्रिका क्षति और एलर्जी प्रतिक्रिया शामिल हैं। अगर आपको बुखार, ठंड लगना, असामान्य रक्तस्राव, सुनने में परेशानी या पेशाब कम आना जैसी समस्या हो तो तुरंत अपने डॉक्टर को बताएं।
सुरक्षा सलाह: यह दवा केवल अस्पताल या कैंसर केंद्र में योग्य स्वास्थ्यकर्मी द्वारा दी जाती है। इसे घर पर स्वयं न लगाएं। हर खुराक से पहले डॉक्टर आपके रक्त, गुर्दे की कार्यप्रणाली और सुनने की जांच करेंगे। अगर आपको गुर्दे, सुनने या हाथ-पैरों में झुनझुनी की समस्या है, या आप गर्भवती हैं या गर्भधारण की योजना बना रही हैं, तो डॉक्टर को बताएं। अपने डॉक्टर की सलाह के अनुसार पर्याप्त पानी पिएं। संक्रमण से बचने के लिए हाथ धोते रहें और भीड़-भाड़ वाली जगहों से बचें। इलाज के दौरान और उसके बाद कुछ समय तक गर्भनिरोधक उपाय अपनाएं। बुखार, ठंड लगना, असामान्य रक्तस्राव, सुनने में कठिनाई या पेशाब कम आने पर तुरंत डॉक्टर से संपर्क करें।
💊 cisget 50mg injection Uses & Benefits
[{"condition":"Testicular cancer","description":"This medicine is a key part of combination chemotherapy regimens used to cure testicular cancer, often given with other anticancer drugs.","evidence":"Well-established"},{"condition":"Ovarian cancer","description":"Used in combination with other chemotherapy agents for advanced ovarian cancer, both as initial treatment and for recurrent disease.","evidence":"Well-established"},{"condition":"Bladder cancer","description":"Given as part of combination chemotherapy for advanced or metastatic bladder cancer and sometimes before surgery.","evidence":"Well-established"},{"condition":"Non-small cell lung cancer","description":"Used in combination with other chemotherapy drugs for advanced non-small cell lung cancer.","evidence":"Well-established"},{"condition":"Head and neck cancers","description":"Used in combination regimens for locally advanced or recurrent head and neck squamous cell carcinoma.","evidence":"Well-established"},{"condition":"Cervical cancer","description":"Given together with radiation therapy for locally advanced cervical cancer.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Small cell lung cancer","description":"Sometimes used in combination regimens for small cell lung cancer, although other platinum agents may be preferred.","evidence":"Limited"},{"condition":"Gastric cancer","description":"Occasionally used in combination chemotherapy for advanced gastric cancer.","evidence":"Limited"},{"condition":"Mesothelioma","description":"Used in some combination regimens for malignant mesothelioma, though other agents are more commonly used.","evidence":"Limited"}]
Primary treatment for: Cancer (various types, including testicular, ovarian, bladder, lung, and head and neck cancers)
Also treats: Cervical cancer, Gastric cancer, Mesothelioma
📋 Drug Information
| Generic Name(s) | Cisplatin |
| Brand Name | Blastolem 50mg Injection |
| Manufacturer | Getwell Pharmaceutical Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | Platinum compounds-Anticancer |
| Route of Administration | Intravenous (into a vein) |
| Storage | Store this medicine in its original container in a refrigerator at 2°C to 8°C. Do not freeze. Protect from light. Keep out of reach of children. Once prepared for infusion, use as directed by the healthcare professional. |
| Shelf Life | The shelf life is typically 24 months from the date of manufacture when stored as directed. Check the expiry date on the label. Do not use if the solution is discoloured or contains particles. |
| WHO Guideline | Not established from the available information. Treatment guidelines for cisplatin are typically developed by national and international oncology bodies, and your oncologist will follow the appropriate protocol for your specific cancer. |
| ICMR Guideline | Not established from the available information. In India, cancer treatment guidelines are available from ICMR and other national bodies, and your oncologist will follow the appropriate protocol for your specific cancer. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by entering cancer cells and becoming activated to form reactive platinum species that bind strongly to DNA. The platinum atoms form cross-links between strands of DNA, which prevents the DNA from being copied and repaired properly. This stops cancer cells from dividing and triggers cell death. Because cancer cells divide more often than most normal cells, they are more affected by this medicine, but some normal tissues such as the kidneys, nerves, and inner ear can also be harmed.
Mechanism Steps
💡 How to Take cisget 50mg injection
Strength: Injection: 50 mg per vial (50 mg/50 mL or as specified by the manufacturer). This medicine is a sterile concentrate for solution for infusion.
Dosage Information
| Adult Dosage | The dose of this medicine is determined by your oncologist based on the type of cancer, your body size, kidney function, and overall health. It is usually given as an intravenous infusion over several hours. Common regimens may use doses ranging from 50 to 100 mg per square meter of body surface area, repeated every 3 to 4 weeks, but the exact dose and schedule must be individualized by a qualified clinician. This medicine is always given with plenty of fluids and anti-sickness medicines to reduce side effects. Never attempt to adjust the dose yourself. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatric oncologist for individualized dosing. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially kidney damage, hearing loss, and nerve damage. Kidney function declines with age, so the dose may need to be reduced. Close monitoring of kidney function, blood counts, and hearing is recommended. The dose must be individualized by a qualified clinician. |
| Renal Impairment | This medicine is mainly removed by the kidneys. Patients with kidney problems may need a lower dose or may not be able to receive this medicine at all. Kidney function tests are done before each cycle. If kidney function worsens, the dose may be reduced or treatment may be delayed. Adequate hydration is essential. The dose must be individualized by a qualified clinician. |
| Hepatic Impairment | This medicine is not primarily metabolized by the liver, so liver problems may not require a dose change. However, patients with severe liver impairment should be monitored closely. The dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | The maximum dose is determined by the treatment protocol and must not exceed the dose prescribed by your oncologist. Doses are usually calculated based on body surface area and given in cycles. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of cisget 50mg injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Gentamicin | Major | |
| Amphotericin B | Major | |
| Vancomycin | Major | |
| Ibuprofen | Major | |
| Live vaccines | Major | |
| Phenytoin | Major | |
| Furosemide | Moderate | |
| Paclitaxel | Moderate | |
| Docetaxel | Moderate | |
| Bleomycin | Major |
🚨 Major Interactions
- Aminoglycoside antibiotics (e.g., gentamicin, amikacin)
- Other nephrotoxic drugs (e.g., amphotericin B, vancomycin, NSAIDs)
- Live vaccines
- Phenytoin
- Bleomycin and other anticancer drugs
⚡ Moderate Interactions
- Loop diuretics (e.g., furosemide)
- Paclitaxel
- Docetaxel
🍷 Alcohol Interaction
Alcohol should be avoided while receiving this medicine. Alcohol can worsen nausea, vomiting, dehydration, and liver stress, and may increase the risk of stomach irritation. It can also make it harder for your body to recover between chemotherapy cycles. Ask your doctor for personalized advice.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known severe allergic reaction to cisplatin or other platinum-containing medicines","Severe kidney impairment","Severe bone marrow suppression","Pre-existing hearing loss","Pregnancy","Breastfeeding","Severe liver impairment","Active uncontrolled infection"]
⚠️ Warnings & Precautions
["This medicine must only be given by a qualified healthcare professional in a hospital or cancer centre.","Kidney function must be checked before and during treatment. Adequate hydration is essential.","Hearing tests may be needed before and during treatment, especially with high doses or in elderly patients.","Blood counts must be monitored closely because this medicine can cause severe bone marrow suppression.","This medicine can cause nerve damage. Report numbness, tingling, or weakness in hands or feet.","Avoid live vaccines during treatment.","Use effective contraception during treatment and for a period after treatment as advised by your doctor.","This medicine can cause severe nausea and vomiting. Anti-sickness medicines are usually given before and after infusion.","Tell your doctor if you have any kidney, liver, or hearing problems before starting treatment.","This medicine can cause blood clots. Report sudden leg pain, swelling, chest pain, or shortness of breath."]
🤱 Lactation Safety
This medicine passes into breast milk and may harm the nursing infant. Breastfeeding is not recommended during treatment and for some time after the last dose. Discuss with your doctor about alternative feeding options.
💊 Overdose Management
Overdose of this medicine can cause severe kidney damage, bone marrow suppression, hearing loss, and nerve damage. There is no specific antidote. Treatment is supportive and may include intensive hydration, monitoring of blood counts and kidney function, and management of symptoms. If an overdose is suspected, seek emergency medical help immediately.
⏰ Missed Dose
This medicine is given by a healthcare professional in a hospital or clinic. If you miss a scheduled appointment for your dose, contact your cancer care team as soon as possible to reschedule. Do not try to self-administer this medicine at home. Your doctor will decide when to give the next dose based on your blood counts and overall condition.
Additional Safety Advice
This medicine must only be given by a qualified healthcare professional in a hospital or cancer centre. It is not for self-administration at home. Before each dose, your doctor will check your blood counts, kidney function, and hearing, and may adjust or delay the dose based on the results. Tell your doctor if you have kidney problems, hearing problems, numbness or tingling in your hands or feet, or if you are pregnant or planning pregnancy. Drink plenty of fluids as advised by your care team to help protect your kidneys. Avoid close contact with people who have infections, and wash your hands often. Do not receive any live vaccines while on this medicine without asking your doctor. Use effective contraception during treatment and for some time after, as advised by your doctor. Report any fever, chills, unusual bleeding or bruising, difficulty hearing, or reduced urine output immediately.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more likely to experience kidney damage, hearing loss, and nerve damage from this medicine. Kidney function declines with age, so the dose may need to be reduced. Close monitoring of kidney function, blood counts, and hearing is recommended. Discuss any concerns with your doctor.
🤰 Pregnancy Planning (TTC)
This medicine can harm the unborn baby and may affect fertility. If you are planning pregnancy, discuss fertility preservation options with your doctor before starting treatment. Use effective contraception during treatment and for a period after, as advised by your doctor. If you become pregnant during treatment, contact your doctor immediately.
🏥 Post-Surgery Considerations
If you have surgery planned, inform your surgeon and oncologist that you are receiving this medicine. It can affect wound healing and increase the risk of bleeding and infection. Your doctor will advise on the timing of surgery in relation to your chemotherapy cycles.
🦷 Dental Procedures
Inform your dentist that you are receiving this medicine before any dental procedure. This medicine can increase the risk of bleeding and infection. Your dentist may recommend delaying non-urgent procedures until your blood counts recover. Good oral hygiene is important to prevent mouth sores and infections.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Mild to moderate exercise may help with fatigue and overall well-being, but you should avoid strenuous activity during treatment, especially if you have low blood counts, fever, or feel very tired. Always consult your doctor before starting any exercise program. Avoid activities that increase the risk of falls or injury if you have numbness or weakness in your hands or feet.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause tiredness, nausea, and other side effects that may affect your ability to work during treatment. You may need to take time off for infusions and recovery. Do not drive or operate machinery immediately after infusion or if you feel unwell. Discuss your work schedule with your doctor and employer to plan for time off and adjustments.
🛑 When to Stop This Medicine
Do not stop this medicine on your own. Your oncologist will decide when to stop based on your response to treatment, side effects, and overall health. If you experience severe side effects, your doctor may delay, reduce, or stop treatment. Always consult your doctor before making any changes.
📅 Long-Term Use Effects
Long-term effects of this medicine can include persistent kidney problems, hearing loss, nerve damage, and an increased risk of secondary cancers. Regular follow-up with your doctor is important to monitor for these effects. Some side effects may improve over time, but others may be permanent. Your doctor will monitor your kidney function, hearing, and neurological health during and after treatment.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Another platinum-based chemotherapy drug that may be used instead of cisplatin in some cases, with different side effect profiles.
Evidence: Well-establishedFor some cancers, targeted drugs may be used alone or in combination with chemotherapy.
Evidence: Well-established for specific cancersMay be an option for certain cancers, either alone or with chemotherapy.
Evidence: Well-established for specific cancers💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Live vaccines should not be given during treatment with this medicine because they can cause serious infections. Inactivated vaccines may be given, but their effectiveness may be reduced. Discuss vaccination timing with your doctor. Avoid close contact with people who have recently received live vaccines.
📦 Storage Guide
✅ DO
Store in a refrigerator at 2°C to 8°C
❌ DON'T
Do not freeze
✅ DO
Keep in original container and protect from light
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep out of reach of children
❌ DON'T
Do not use if the solution is discoloured or contains particles
✅ DO
Check the expiry date before use
❌ DON'T
Do not use after the expiry date
✈️ Traveling with This Medicine
This medicine is given in a hospital or cancer centre, so travel should be planned around your treatment schedule. If you need to travel, carry a copy of your prescription and a letter from your doctor explaining your treatment. Keep the medicine in its original packaging and store it as directed, usually in a refrigerator. Check with your airline and customs about carrying injectable medicines. Plan for adequate hydration during travel and avoid crowded places to reduce infection risk. Discuss any travel plans with your oncologist in advance.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within hours of infusion, but visible clinical response may take weeks to months. Your doctor will monitor your progress with regular tests and scans.
A: This medicine is given as an intravenous infusion in a hospital or cancer centre. It is not taken at home.
A: Common side effects include nausea, vomiting, tiredness, loss of appetite, and low blood counts. Anti-sickness medicines are usually given to help.
A: No, this medicine can harm the unborn baby and is not recommended during pregnancy. Use effective contraception during treatment.
A: Avoid alcohol, live vaccines, and close contact with people who have infections. Drink plenty of fluids as advised.
🤔 Common Patient Concerns
🔄 Substitutes for cisget 50mg injection
View AllAlternative brands with exact same active ingredient:
-
cizcan 50mg injectionNeon Laboratories Ltd ₹261.16 38.6% CHEAPER
-
Stritin 50mg InjectionMylan Pharmaceuticals Pvt Ltd ₹284.82 33% CHEAPER
-
oncoplatin aq 50mg infusionSun Pharmaceutical Industries Ltd ₹300.00 29.4% CHEAPER
-
cisteen 50mg infusionVhb Life Sciences Inc ₹309.52 27.2% CHEAPER
-
cytoplatin 50mg infusionCipla Ltd ₹314.53 26% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken as a pill at home.
Fact: This medicine is given only by intravenous infusion in a hospital or cancer centre under medical supervision. - Myth: This medicine is safe for everyone with cancer.
Fact: This medicine is not suitable for everyone. It is avoided in people with severe kidney problems, hearing loss, or severe bone marrow suppression. - Myth: You can stop this medicine whenever you feel better.
Fact: Treatment schedules are carefully planned by your oncologist. Do not stop or change your treatment without consulting your doctor. - Myth: This medicine does not affect fertility.
Fact: This medicine can affect fertility. Discuss fertility preservation options with your doctor before starting treatment if this is a concern.
🔄 Alternative Options
Generic Alternatives
- Cisplatin injection
Brand Alternatives
- Blastolem 50mg injection