cipropen eye/ear drops

4.4 (18 reviews)

Ciprofloxacin (0.3% w/v)

🏭 Morepen Laboratories Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 22, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 22, 2026

What is cipropen eye/ear drops used for?

Biocip Eye/Ear Drops (Ciprofloxacin) is used to treat OPHTHAL OTOLOGICALS. It contains Ciprofloxacin (0.3% w/v), which Inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication. Always consult your doctor before use. Take as prescribed.

Generic Name: Ciprofloxacin
Manufacturer: Morepen Laboratories Ltd
Form: Allopathy
Pregnancy Category: C
Prescription Required: Yes

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 cipropen eye/ear drops Uses & Benefits

Bacterial conjunctivitis, keratitis, blepharitis, otitis externa, otitis media with tympanostomy tubes

Off-label uses: Prophylaxis in ocular surgery, treatment of corneal ulcers

📋 Drug Information

Generic Name(s)	Ciprofloxacin
Brand Name	Biocip Eye/Ear Drops
Manufacturer	Morepen Laboratories Ltd
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	OPHTHAL OTOLOGICALS
Action Class	Quinolones/ Fluroquinolones
Route of Administration	Ophthalmic and otic topical
Storage	Store at 15-30°C, protect from light
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionMinimal systemic absorption after topical application

DistributionDistributes into ocular tissues and fluids; minimal systemic distribution

Protein Binding20-40%

MetabolismHepatic (partially metabolized)

Half-Life4 hours (systemic)

ExcretionRenal (systemic); negligible after topical use

BioavailabilityNegligible systemic bioavailability after topical application

Onset of ActionRapid (within minutes)

Peak Plasma TimeNot applicable (topical)

Duration of Action6-8 hours

How It Works

Inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication

Mechanism Steps

1Ciprofloxacin enters bacterial cell through porin channels

2Binds to DNA gyrase (topoisomerase II) and topoisomerase IV

3Inhibits DNA supercoiling and replication

💡 How to Take cipropen eye/ear drops

Follow your doctor's prescription exactly.

⚠️ Side Effects of cipropen eye/ear drops

✅ Common Side Effects

Eye irritation
Burning
Stinging
Blurred vision
Taste perversion

🚨 Serious Side Effects

Hypersensitivity reactions
Tendon rupture (rare with topical)
Clostridium difficile diarrhea (rare)

⚠️ Rare Side Effects

Corneal deposits
Peripheral neuropathy
QT prolongation

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Warfarin	Major	Increased bleeding risk
Theophylline	Major	Increased theophylline levels, risk of toxicity
Tizanidine	Major	Increased tizanidine levels, hypotension, sedation
NSAIDs	Moderate	Increased risk of CNS stimulation and seizures
Corticosteroids	Moderate	Increased risk of tendon rupture
Cyclosporine	Moderate	Increased nephrotoxicity risk
Antacids	Minor	Reduced absorption if taken orally (not relevant for topical)
Sucralfate	Minor	Reduced absorption if taken orally
Iron supplements	Minor	Reduced absorption if taken orally

🚨 Major Interactions

Warfarin
Theophylline
Tizanidine

⚡ Moderate Interactions

NSAIDs
Corticosteroids
Cyclosporine

ℹ️ Minor Interactions

Antacids
Sucralfate
Iron supplements

🍽️ Food Interactions

No significant food interactions for topical use

🍷 Alcohol Interaction

No known interaction

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to ciprofloxacin or any quinolone

📊 Monitoring Parameters

Clinical improvement, signs of hypersensitivity, corneal epithelial healing

🤱 Lactation Safety

Use with caution; limited data

💊 Overdose Management

Flush eye/ear with water; supportive care

⏰ Missed Dose

Apply as soon as remembered; skip if near next dose

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

🔗 View Profile

🔄 Substitutes for cipropen eye/ear drops

View All

Alternative brands with exact same active ingredient (Ciprofloxacin (0.3% w/v)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Trusted Reviewer Jul 10, 2026

Found this to be a helpful product. Good results.

Regular Customer Jul 10, 2026

Effective and reliable. Worked as expected.

Verified User Jul 10, 2026