cilotab 50mg tablet - Cilostazol (50mg) medicine

cilotab 50mg tablet - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Icon Life Sciences ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 29, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 29, 2026

What is cilotab 50mg tablet used for?

Cilodoc 50 Tablet (Cilostazol) is used to treat CARDIAC. It contains Cilostazol (50mg), which Inhibits phosphodiesterase type 3 (PDE3), leading to increased cAMP levels in pl. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Cilostazol
  • Manufacturer: Icon Life Sciences
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

๐Ÿ’Š cilotab 50mg tablet Uses & Benefits

Intermittent claudication due to peripheral arterial disease.

Off-label uses: Prevention of stroke (not FDA approved), prevention of restenosis after coronary stenting (limited evidence).

๐Ÿ“‹ Drug Information

Generic Name(s)Cilostazol
Brand NameCilodoc 50 Tablet
ManufacturerIcon Life Sciences
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassPhosphodiesterase III Inhibiotrs (PVD)
Route of AdministrationOral
StorageStore at 20-25ยฐC (68-77ยฐF); protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed after oral administration; absolute bioavailability is not determined.
DistributionDistributes widely; volume of distribution is approximately 2.5 L/kg.
Protein Binding95-98% bound to plasma proteins, mainly albumin.
MetabolismExtensively metabolized in the liver via CYP3A4 and CYP2C19, and to a lesser extent by CYP1A2 and CYP2D6.
Half-Life11-13 hours
ExcretionPrimarily excreted in urine (74%) as metabolites; 20% in feces.
BioavailabilityNot determined; absorption is rapid.
Onset of ActionWithin 2-4 weeks for symptomatic improvement in intermittent claudication.
Peak Plasma Time3-4 hours
Duration of ActionNot well defined; effects persist with continued dosing.

How It Works

Inhibits phosphodiesterase type 3 (PDE3), leading to increased cAMP levels in platelets and vascular smooth muscle, resulting in antiplatelet and vasodilatory effects.

Mechanism Steps

1Cilostazol is absorbed orally and reaches peak plasma concentration in 3-4 hours.
2It binds to PDE3 enzyme in platelets and vascular smooth muscle cells.
3Inhibition of PDE3 prevents breakdown of cAMP, leading to increased intracellular cAMP levels.

๐Ÿ’ก How to Take cilotab 50mg tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of cilotab 50mg tablet

โœ… Common Side Effects

  • Headache
  • Diarrhea
  • Abnormal stools
  • Palpitations
  • Dizziness

๐Ÿšจ Serious Side Effects

  • Bleeding (e.g., intracranial hemorrhage, GI bleeding)
  • Thrombocytopenia
  • Ventricular tachycardia
  • Heart failure exacerbation

โš ๏ธ Rare Side Effects

  • Hepatitis
  • Agranulocytosis
  • Stevens-Johnson syndrome
  • Anaphylaxis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Ketoconazole Major Increased cilostazol levels; avoid coadministration.
Omeprazole Major Increased cilostazol levels; consider dose adjustment.
Warfarin Moderate Increased bleeding risk; monitor INR.
Aspirin Moderate Increased bleeding risk; monitor for signs of bleeding.
Grapefruit juice Minor May increase cilostazol levels; avoid.

๐Ÿšจ Major Interactions

  • CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, erythromycin)
  • CYP2C19 inhibitors (e.g., omeprazole, ticlopidine)

โšก Moderate Interactions

  • Anticoagulants (e.g., warfarin)
  • Antiplatelet agents (e.g., aspirin, clopidogrel)
  • CYP3A4 inducers (e.g., rifampin, carbamazepine)

โ„น๏ธ Minor Interactions

  • Grapefruit juice
  • CYP2C19 inducers (e.g., rifampin)

๐Ÿฝ๏ธ Food Interactions

Grapefruit juice may increase cilostazol levels; avoid concurrent use.

๐Ÿท Alcohol Interaction

No specific interaction; however, alcohol may increase bleeding risk in combination with antiplatelet effects.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Congestive heart failure, history of hemorrhagic stroke, active bleeding, severe hepatic impairment, hypersensitivity.

๐Ÿ“Š Monitoring Parameters

Signs of bleeding, heart rate, blood pressure, liver function tests periodically.

๐Ÿคฑ Lactation Safety

Not recommended; unknown if excreted in human milk.

๐Ÿ’Š Overdose Management

Symptomatic and supportive; no specific antidote. Monitor for severe headache, diarrhea, hypotension, and tachycardia.

โฐ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose. Do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 29, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for cilotab 50mg tablet

View All

Alternative brands with exact same active ingredient (Cilostazol (50mg)):

Medical Note: Always consult your doctor before switching medications.

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