cilnikem-beta 2.5 tablet
What is cilnikem-beta 2.5 tablet used for?
This medicine contains Nebivolol (2.5mg) + Cilnidipine (10mg) and is used to treat CARDIAC. Nebivolol: Selective beta-1 blocker with nitric oxide-mediated vasodilation; Cilnidipine: L-type and. Always consult your doctor before use.
- Generic Name: Nebivolol + Cilnidipine
- Manufacturer: Alkem Laboratories Ltd
- Form: Allopathy
- Pregnancy Category: Category A
- Prescription Required: Yes
💊 cilnikem-beta 2.5 tablet Uses & Benefits
Off-label uses: Chronic stable angina, Heart failure (nebivolol)
📋 Drug Information
| Generic Name(s) | Nebivolol + Cilnidipine |
| Brand Name | Cilacar NB 5 Tablet |
| Manufacturer | Alkem Laboratories Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Antihypertensive (Beta-blocker + Calcium channel blocker) |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25°C), protect from light and moisture. |
| Shelf Life | As per manufacturer |
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Nebivolol: Selective beta-1 blocker with nitric oxide-mediated vasodilation; Cilnidipine: L-type and N-type calcium channel blocker.
Mechanism Steps
💡 How to Take cilnikem-beta 2.5 tablet
Follow your doctor's prescription exactly.
⚠️ Side Effects of cilnikem-beta 2.5 tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| CYP2D6 inhibitors | Major | Increased nebivolol levels |
| CYP3A4 inhibitors | Major | Increased cilnidipine levels |
| Other antihypertensives | Major | Additive hypotension |
| Digoxin | Moderate | Increased bradycardia risk |
| Warfarin | Moderate | Increased INR |
| Insulin/oral hypoglycemics | Moderate | Masked hypoglycemia symptoms |
| Cimetidine | Minor | Slight increase in nebivolol levels |
| Grapefruit juice | Minor | Increased cilnidipine absorption |
🚨 Major Interactions
- CYP2D6 inhibitors (e.g., quinidine, fluoxetine)
- CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
- Other antihypertensives (additive hypotension)
⚡ Moderate Interactions
- Digoxin
- Warfarin
- Insulin/oral hypoglycemics
🍷 Alcohol Interaction
May enhance hypotensive effect; avoid excessive alcohol.
🛡️ Safety & Warnings
🚫 Contraindications
Sick sinus syndrome, heart block (2nd/3rd degree), cardiogenic shock, severe bradycardia, hypersensitivity.
🤱 Lactation Safety
Not recommended; avoid breastfeeding.
💊 Overdose Management
Symptomatic and supportive; monitor ECG, blood pressure; consider atropine for bradycardia.
⏰ Missed Dose
Take as soon as remembered; skip if near next dose; do not double.
🔄 Substitutes for cilnikem-beta 2.5 tablet
View AllAlternative brands with exact same active ingredient:
-
cinod-n 10/2.5 tabletAjanta Pharma Ltd ₹89.06 48% CHEAPER
-
nebifid cn 2.5mg/10mg tabletFidelity Lifesciences Pvt Ltd ₹103.13 39.7% CHEAPER
-
nebistar ln 2.5mg/10mg tabletLupin Ltd ₹157.60 7.9% CHEAPER
-
cilacar nb 2.5 tabletJ B Chemicals and Pharmaceuticals Ltd ₹165.69 3.2% CHEAPER
-
nebicard ln 2.5 tabletTorrent Pharmaceuticals Ltd ₹169.26 1.1% CHEAPER
Medical Note: Always consult your doctor before switching medications.