chlor h eye ointment - Chloramphenicol (1% w/w) + Hydrocortisone (0.5% w/w) medicine

chlor h eye ointment

5.0 (14 reviews)
๐Ÿญ Jainson Biotech (India) Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 23, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 23, 2026

What is chlor h eye ointment used for?

Belmycetine C Eye Ointment (Chloramphenicol + Hydrocortisone) is used to treat OPHTHAL OTOLOGICALS. It contains Chloramphenicol (1% w/w) + Hydrocortisone (0.5% w/w), which Chloramphenicol inhibits bacterial protein synthesis by binding to 50S ribosomal. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Chloramphenicol + Hydrocortisone
  • Manufacturer: Jainson Biotech (India) Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

๐Ÿ’Š chlor h eye ointment Uses & Benefits

Bacterial conjunctivitis with inflammation; blepharitis; keratitis

Off-label uses: Prevention of ocular infections post-surgery

๐Ÿ“‹ Drug Information

Generic Name(s)Chloramphenicol + Hydrocortisone
Brand NameBelmycetine C Eye Ointment
ManufacturerJainson Biotech (India) Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassOPHTHAL OTOLOGICALS
Action ClassAntibiotic + Corticosteroid
Route of AdministrationOphthalmic (topical)
StorageStore at 15-25ยฐC; protect from light; keep tightly closed
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionMinimal systemic absorption through ocular route
DistributionDistributes into ocular tissues; systemic distribution negligible
Protein BindingChloramphenicol: 50-60%; Hydrocortisone: 90%
MetabolismChloramphenicol: Hepatic via glucuronidation; Hydrocortisone: Hepatic
Half-LifeChloramphenicol: 1.5-4 hours; Hydrocortisone: 1-2 hours
ExcretionChloramphenicol: Renal (90%); Hydrocortisone: Renal
BioavailabilityLow systemic bioavailability via ocular route
Onset of ActionWithin 24-48 hours
Peak Plasma TimeNot applicable (topical ocular)
Duration of Action6-8 hours

How It Works

Chloramphenicol inhibits bacterial protein synthesis by binding to 50S ribosomal subunit; Hydrocortisone suppresses inflammation by inhibiting phospholipase A2 and reducing prostaglandin synthesis

Mechanism Steps

1Chloramphenicol binds to 50S ribosomal subunit of bacteria
2Inhibits peptide bond formation and protein synthesis
3Bacteriostatic effect on susceptible organisms

๐Ÿ’ก How to Take chlor h eye ointment

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of chlor h eye ointment

โœ… Common Side Effects

  • Burning
  • Stinging
  • Blurred vision
  • Eye irritation

๐Ÿšจ Serious Side Effects

  • Bone marrow suppression (aplastic anemia)
  • Optic neuritis
  • Increased intraocular pressure
  • Cataract formation

โš ๏ธ Rare Side Effects

  • Hypersensitivity reactions
  • Secondary infections
  • Delayed wound healing

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk due to inhibition of warfarin metabolism
Phenytoin Major Increased phenytoin levels and toxicity
Phenobarbital Major Decreased chloramphenicol efficacy
Rifampin Major Decreased chloramphenicol efficacy
Oral contraceptives Moderate Reduced contraceptive efficacy
Antidiabetic agents Moderate Altered blood glucose levels
NSAIDs Moderate Increased risk of gastrointestinal bleeding
Antacids Minor Reduced absorption of chloramphenicol
Cimetidine Minor Increased chloramphenicol levels

๐Ÿšจ Major Interactions

  • Warfarin
  • Phenytoin
  • Phenobarbital
  • Rifampin

โšก Moderate Interactions

  • Oral contraceptives
  • Antidiabetic agents
  • NSAIDs

โ„น๏ธ Minor Interactions

  • Antacids
  • Cimetidine

๐Ÿฝ๏ธ Food Interactions

None significant

๐Ÿท Alcohol Interaction

None significant

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to chloramphenicol or hydrocortisone; viral, fungal, or tubercular eye infections; untreated eye infections

๐Ÿ“Š Monitoring Parameters

Ocular examination; signs of superinfection; intraocular pressure if prolonged use

๐Ÿคฑ Lactation Safety

Caution; chloramphenicol excreted in breast milk; risk of bone marrow suppression in infant

๐Ÿ’Š Overdose Management

Rare; flush eye with water; symptomatic treatment

โฐ Missed Dose

Apply as soon as remembered; skip if almost time for next dose; do not double dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 23, 2026

๐Ÿ”— View Profile

โญ User Reviews

Verified User Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Regular Customer Jul 10, 2026

Found this to be a helpful product. Good results.

Verified User Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Verified User Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Regular Customer Jul 10, 2026

Effective and reliable. Worked as expected.

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