chlor d eye/ear drops - Chloramphenicol (0.5% w/v) + Dexamethasone (0.1% w/v) medicine

chlor d eye/ear drops

4.5 (14 reviews)
๐Ÿญ Jainson Biotech (India) Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 23, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 23, 2026

What is chlor d eye/ear drops used for?

Anchlor-DX Eye Ointment (Chloramphenicol + Dexamethasone) is used to treat OPHTHAL. It contains Chloramphenicol (0.5% w/v) + Dexamethasone (0.1% w/v), which Chloramphenicol inhibits bacterial protein synthesis by binding to 50S ribosomal. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Chloramphenicol + Dexamethasone
  • Manufacturer: Jainson Biotech (India) Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

๐Ÿ’Š chlor d eye/ear drops Uses & Benefits

Treatment of bacterial eye infections with inflammation (e.g., conjunctivitis, blepharitis)

Off-label uses: Prophylaxis after ocular surgery

๐Ÿ“‹ Drug Information

Generic Name(s)Chloramphenicol + Dexamethasone
Brand NameAnchlor-DX Eye Ointment
ManufacturerJainson Biotech (India) Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassOPHTHAL
Action ClassAntibiotic + Corticosteroid
Route of AdministrationOphthalmic (topical)
StorageStore at 15-30ยฐC; protect from light; keep tightly closed
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionMinimal systemic absorption after ophthalmic application
DistributionLocal distribution in ocular tissues; negligible systemic distribution
Protein BindingChloramphenicol: 50-60%; Dexamethasone: 70-80%
MetabolismChloramphenicol: Hepatic via glucuronidation; Dexamethasone: Hepatic
Half-LifeChloramphenicol: 1.5-4 hours; Dexamethasone: 3-4 hours
ExcretionChloramphenicol: Renal (90% as inactive metabolites); Dexamethasone: Renal
BioavailabilityLow systemic bioavailability due to topical ophthalmic route
Onset of ActionWithin 24-48 hours
Peak Plasma TimeNot applicable (topical); local effect within hours
Duration of Action6-8 hours

How It Works

Chloramphenicol inhibits bacterial protein synthesis by binding to 50S ribosomal subunit; Dexamethasone suppresses inflammation by inhibiting phospholipase A2 and reducing prostaglandin synthesis

Mechanism Steps

1Chloramphenicol binds to 50S ribosomal subunit of bacteria, inhibiting peptide bond formation and protein synthesis
2Dexamethasone binds to glucocorticoid receptors, inducing lipocortin synthesis which inhibits phospholipase A2
3Inhibition of phospholipase A2 reduces arachidonic acid release, decreasing prostaglandin and leukotriene synthesis

๐Ÿ’ก How to Take chlor d eye/ear drops

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of chlor d eye/ear drops

โœ… Common Side Effects

  • Burning
  • Stinging
  • Blurred vision
  • Eye irritation

๐Ÿšจ Serious Side Effects

  • Bone marrow suppression (aplastic anemia) with prolonged systemic use
  • Increased intraocular pressure
  • Cataract formation

โš ๏ธ Rare Side Effects

  • Hypersensitivity reactions
  • Superinfection
  • Delayed wound healing

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk due to inhibition of warfarin metabolism by chloramphenicol
Phenytoin Major Increased phenytoin levels and toxicity
Phenobarbital Major Decreased chloramphenicol efficacy due to enzyme induction
Rifampin Major Decreased chloramphenicol efficacy due to enzyme induction

๐Ÿšจ Major Interactions

  • Warfarin
  • Phenytoin
  • Phenobarbital
  • Rifampin

โšก Moderate Interactions

  • Oral contraceptives
  • Antidiabetic agents
  • Cyclosporine

โ„น๏ธ Minor Interactions

  • Antacids
  • Cimetidine

๐Ÿฝ๏ธ Food Interactions

No significant food interactions

๐Ÿท Alcohol Interaction

No known interaction

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to chloramphenicol, dexamethasone, or any component; viral, fungal, or mycobacterial eye infections; untreated eye infections

๐Ÿ“Š Monitoring Parameters

Clinical response; intraocular pressure if prolonged use; signs of secondary infection

๐Ÿคฑ Lactation Safety

Caution; small amounts may be excreted in breast milk

๐Ÿ’Š Overdose Management

Unlikely with topical use; if ingested, symptomatic treatment

โฐ Missed Dose

Apply as soon as remembered; skip if almost time for next dose; do not double

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 23, 2026

๐Ÿ”— View Profile

โญ User Reviews

Happy Patient Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Certified Buyer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Certified Buyer Jul 10, 2026

Effective and reliable. Worked as expected.

Regular Customer Jul 10, 2026

Found this to be a helpful product. Good results.

Happy Patient Jul 10, 2026

Effective and reliable. Worked as expected.

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