childryl syrup - Promethazine (1.5mg/5ml) + Pholcodine (1.5mg/5ml) medicine

Childryl Syrup: Complete Medicine Guide

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🏭 Mandar Pharmaceuticals Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 21, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Limited
Reviewed by
SaathiMed Expert Panel | Oct 21, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or slow, shallow breathing
  • Severe drowsiness or confusion
  • Rash, itching, or swelling of the face, lips, or throat
  • Unusual bruising or bleeding
  • Seizures
  • Inability to pass urine
  • Fast or irregular heartbeat

If experiencing severe symptoms, call emergency services immediately.

What is childryl syrup used for?

This medicine is a combination of promethazine and pholcodine used for short-term relief of dry, irritating cough. It works by blocking histamine and suppressing the cough reflex in the brain. It is not for children under 6 years and should not be used for productive cough.

  • Generic Name: Promethazine + Pholcodine
  • Manufacturer: Mandar Pharmaceuticals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 childryl syrup के बारे में (Hindi Summary)

उपयोग: यह दवा सूखी, खुजली वाली खांसी के इलाज के लिए इस्तेमाल की जाती है। इसमें प्रोमेथाज़ीन और फोलकोडीन दो सक्रिय तत्व होते हैं जो खांसी को कम करने में मदद करते हैं। यह दवा 6 साल से बड़े बच्चों और वयस्कों के लिए है। इसका इस्तेमाल केवल डॉक्टर की सलाह पर ही करें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, चक्कर आना, मुंह सूखना, धुंधली दृष्टि, जी मिचलाना और कब्ज शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन सांस लेने में कठिनाई, गंभीर एलर्जी या असामान्य खून बहना हो सकता है। अगर कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुद से मात्रा न बढ़ाएं। इस दवा को लेने के बाद गाड़ी चलाने या मशीन चलाने से बचें क्योंकि इससे नींद आ सकती है। शराब का सेवन बिल्कुल न करें। बच्चों की पहुंच से दूर रखें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 childryl syrup Uses & Benefits

[{"condition":"Dry, irritating cough","description":"This medicine is used for short-term relief of non-productive cough in adults and children above 6 years.","evidence":"Established"},{"condition":"Allergic cough","description":"The antihistamine component helps reduce cough triggered by allergies.","evidence":"Limited"}]

Off-label uses: []

Primary treatment for: Dry cough

Also treats: Allergic cough

📋 Drug Information

Generic Name(s)Promethazine + Pholcodine
Brand NameChildryl Syrup
ManufacturerMandar Pharmaceuticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassAntitussive + Antihistamine
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep the bottle tightly closed.
Shelf LifeNot established from the available information.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Use this medicine only for dry, non-productive cough and for a short duration.
2
Avoid giving this medicine to children under 6 years of age.
3
Warn patients about drowsiness and advise against driving or operating machinery.
4
Check for interactions with other CNS depressants, especially in elderly patients.
5
Monitor for anticholinergic side effects like urinary retention and constipation.
6
Do not prescribe for productive cough or chronic respiratory conditions without further evaluation.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Dry cough
This medicine is commonly prescribed for this.
Likely Use
❌
Productive cough
This medicine is not for productive cough.
Not Primary
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionNot established from the available information.
DistributionNot established from the available information.
Protein BindingNot established from the available information.
MetabolismNot established from the available information.
Half-LifeNot established from the available information.
ExcretionNot established from the available information.
BioavailabilityNot established from the available information.
Onset of ActionNot established from the available information.
Peak Plasma TimeNot established from the available information.
Duration of ActionNot established from the available information.

How It Works

This medicine works through two complementary mechanisms. Promethazine is a first-generation antihistamine that blocks histamine H1 receptors, reducing allergic symptoms and causing sedation. It also has anticholinergic effects that dry secretions. Pholcodine is an opioid antitussive that acts on opioid receptors in the central nervous system to suppress the cough reflex. Together, they reduce cough frequency and severity.

Mechanism Steps

1
Histamine H1 receptor blockade: Promethazine binds to histamine H1 receptors, preventing histamine from triggering allergic responses and cough.
2
Anticholinergic action: Promethazine also blocks acetylcholine receptors, reducing secretions and contributing to dry mouth and blurred vision.
3
Opioid receptor activation: Pholcodine acts on opioid receptors in the cough centre of the brain, suppressing the cough reflex.

💡 How to Take childryl syrup

Strength: Each 5 ml contains Promethazine 1.5 mg and Pholcodine 1.5 mg.

1Shake the bottle well before each use.
2Measure the dose accurately using the measuring cup or spoon provided.
3Take the medicine orally, with or without food.
4Follow the prescribed dosing schedule.
5Do not exceed the recommended dose.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 5 ml to 10 ml taken orally every 4 to 6 hours as needed for cough, not exceeding the maximum daily dose. However, the exact dose must be individualized by a qualified clinician based on the severity of cough, age, weight, renal and hepatic function, and other medications. Do not self-medicate or exceed the prescribed dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the sedative and anticholinergic effects of this medicine. Use with caution and lower doses may be appropriate. Consult a doctor for individualized dosing.
Renal ImpairmentNot established from the available information. Consult your doctor for dose adjustment.
Hepatic ImpairmentNot established from the available information. Consult your doctor for dose adjustment.
Maximum Daily DoseNot established from the available information. Do not exceed the dose prescribed by your doctor.

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
Increases sedation and risk of respiratory depression.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of childryl syrup

✅ Common Side Effects

Drowsiness (Common)
Avoid driving or operating machinery. If persistent, consult your doctor.
Dry mouth (Common)
Sip water or chew sugar-free gum. Consult if severe.
Dizziness (Common)
Rise slowly from sitting or lying position. Avoid driving.
Blurred vision (Common)
Usually temporary. Do not drive if vision is affected.
Nausea (Common)
Take with food if stomach upset occurs.

🚨 Serious Side Effects

Respiratory depression (Rare)
Seek immediate medical attention if breathing becomes slow or shallow.
Severe allergic reaction (Rare)
Stop the medicine and get emergency help if you notice rash, swelling, or difficulty breathing.
Blood disorders (Very rare)
Report unusual bruising, bleeding, or fever to your doctor immediately.

⚠️ Rare Side Effects

Hallucinations
Discontinue and consult a doctor immediately.
Urinary retention
Consult your doctor if you cannot pass urine.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
MAOIs Major
CNS depressants Major
Anticholinergics Moderate
SSRIs Moderate
Antacids Minor

🚨 Major Interactions

  • Monoamine oxidase inhibitors (MAOIs)
  • CNS depressants (e.g., benzodiazepines, opioids, alcohol)

⚡ Moderate Interactions

  • Anticholinergic drugs (e.g., atropine, tricyclic antidepressants)
  • Selective serotonin reuptake inhibitors (SSRIs)

🍷 Alcohol Interaction

Alcohol should be strictly avoided while taking this medicine because it can significantly increase drowsiness, dizziness, and the risk of respiratory depression.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Children under 6 years of age","Known hypersensitivity to promethazine or pholcodine","Respiratory depression","Acute asthma attack","Concurrent use with MAOIs"]

⚠️ Warnings & Precautions

["May cause drowsiness; avoid driving or operating machinery.","Avoid alcohol and other CNS depressants.","Use with caution in elderly patients due to increased risk of confusion and falls.","Use with caution in patients with liver or kidney disease.","Do not use for productive cough or chronic lung disease without medical advice.","May cause anticholinergic effects; use with caution in patients with glaucoma or urinary retention."]

🤱 Lactation Safety

Not established from the available information. Consult your doctor before use.

💊 Overdose Management

Overdose of this medicine can cause severe drowsiness, respiratory depression, seizures, and coma. Seek emergency medical attention immediately. Treatment is supportive and may include activated charcoal, airway management, and monitoring. Do not induce vomiting unless instructed by a healthcare professional.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not increase the dose or take it more often than directed. Avoid driving, operating heavy machinery, or performing tasks that require alertness until you know how this medicine affects you. Do not drink alcohol while taking this medicine, as it can increase drowsiness and breathing problems. Keep this medicine out of reach of children. Do not use this medicine for a productive cough or for long-term treatment without medical advice. If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor before using this medicine. Inform your doctor about all other medicines you are taking, especially sedatives, antidepressants, or pain relievers.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more sensitive to the sedative and anticholinergic effects of this medicine. Use with caution and lower doses may be appropriate. Monitor for confusion, falls, and urinary retention.

🤰 Pregnancy Planning (TTC)

Consult your doctor before using this medicine if you are pregnant, planning pregnancy, or breastfeeding. The safety of this medicine during pregnancy and lactation is not well established.

🏥 Post-Surgery Considerations

This medicine may increase the risk of respiratory depression after surgery. Inform your surgeon and anesthesiologist if you are taking this medicine.

🦷 Dental Procedures

This medicine can cause dry mouth, which may increase the risk of dental problems. Maintain good oral hygiene and inform your dentist if you are taking this medicine.

💚 Lifestyle Tips for Better Results

🏃
Stay hydrated by drinking plenty of fluids.
🥗
Use a humidifier to ease throat irritation.
😴
Avoid smoke and other respiratory irritants.
💧
Get plenty of rest to help your body recover.
🧘
Gargle with warm salt water to soothe your throat.

🏋️ Exercise Considerations

Avoid strenuous exercise while taking this medicine because it can cause drowsiness and dizziness. Light activities are fine if you feel well.

🥗 Diet Recommendations

Drink warm fluids like herbal tea with honey.
Avoid cold and sugary drinks that can irritate the throat.
Eat soft, easy-to-swallow foods.

💼 Impact on Daily Work & Life

This medicine can cause drowsiness and impair your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It may also affect your concentration at work.

🛑 When to Stop This Medicine

Stop taking this medicine if your cough persists for more than 7 days, if you develop a fever, rash, or difficulty breathing, or if your doctor advises you to stop. Do not stop suddenly if you have been taking it for a long time without consulting your doctor.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended. Prolonged use of pholcodine can lead to dependence, and promethazine can cause tolerance and anticholinergic side effects. Regular monitoring by a doctor is advised if extended use is necessary.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Home remedies

Warm fluids, honey, and steam inhalation can help soothe dry cough.

Evidence: Limited
Non-opioid cough suppressants

Dextromethorphan or other non-opioid options may be considered by your doctor.

Evidence: Established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

Not established from the available information.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature and protect it from direct sunlight. If crossing time zones, continue your regular dosing schedule as prescribed. Check local customs regulations regarding controlled substances, as pholcodine may be regulated in some countries.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with a persistent dry cough after a cold
She was prescribed this medicine for 5 days. She took it as directed and found relief from the irritating cough, especially at night. She experienced mild drowsiness, so she avoided driving. Her cough resolved within a week.
💡 Lesson: This medicine can effectively relieve dry cough, but drowsiness is common, so plan activities accordingly.
👤 A 70-year-old man with a history of benign prostatic hyperplasia
He was given this medicine for a dry cough. After two doses, he developed difficulty urinating and confusion. He stopped the medicine and consulted his doctor, who switched him to a safer alternative.
💡 Lesson: Elderly patients with urinary retention should use this medicine with caution due to anticholinergic effects.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts working within 30 to 60 minutes after taking a dose, but the exact onset may vary.

Q: Can I take this medicine with other cough medicines?

A: Do not take other cough medicines without consulting your doctor, as they may contain similar ingredients and increase the risk of side effects.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for childryl syrup

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure any type of cough.
    Fact: This medicine is only for dry, irritating cough and is not effective for productive cough with mucus.
  • Myth: It is safe to take this medicine for a long time.
    Fact: This medicine is for short-term use only. Prolonged use can lead to dependence and other side effects.

📊 Comparison with Similar Medicines

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