chemotere 120mg injection
What is chemotere 120mg injection used for?
Adoxi 20mg Injection Combipack (Docetaxel) is used to treat ANTI NEOPLASTICS. It contains Docetaxel (120mg), which Promotes assembly of microtubules and inhibits their disassembly, leading to mit. Always consult your doctor before use. Take as prescribed.
- Generic Name: Docetaxel
- Manufacturer: Cytogen Pharmaceuticals India Pvt Ltd
- Form: Allopathy
- Pregnancy Category: D
- Prescription Required: Yes
๐ chemotere 120mg injection Uses & Benefits
Breast cancer, non-small cell lung cancer, prostate cancer, gastric cancer, head and neck cancer.
Off-label uses: Ovarian cancer, esophageal cancer, bladder cancer.
๐ Drug Information
| Generic Name(s) | Docetaxel |
| Brand Name | Adoxi 20mg Injection Combipack |
| Manufacturer | Cytogen Pharmaceuticals India Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | Antimicrotubule agents- Taxanes |
| Route of Administration | Intravenous infusion. |
| Storage | Store at 2-8ยฐC; protect from light; do not freeze. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Promotes assembly of microtubules and inhibits their disassembly, leading to mitotic arrest and cell death.
Mechanism Steps
๐ก How to Take chemotere 120mg injection
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of chemotere 120mg injection
โ Common Side Effects
- Neutropenia
- Anemia
- Thrombocytopenia
- Alopecia
- Nausea
- Vomiting
- Diarrhea
- Fatigue
- Peripheral neuropathy
- Myalgia
๐จ Serious Side Effects
- Severe neutropenia with fever
- Hypersensitivity reactions
- Fluid retention
- Cardiotoxicity
- Hepatotoxicity
- Severe diarrhea
- Interstitial pneumonitis
โ ๏ธ Rare Side Effects
- Acute myeloid leukemia
- Severe skin reactions
- Capillary leak syndrome
- Pulmonary fibrosis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Major | Increased docetaxel toxicity |
| Rifampin | Major | Decreased docetaxel efficacy |
| Warfarin | Major | Increased bleeding risk |
| Clopidogrel | Moderate | Increased bleeding risk |
| Cisplatin | Moderate | Increased neuropathy risk |
| Doxorubicin | Moderate | Increased cardiotoxicity risk |
| Dexamethasone | Minor | Reduced docetaxel clearance |
| Diphenhydramine | Minor | Reduced docetaxel clearance |
| Grapefruit juice | Minor | Increased docetaxel exposure |
๐จ Major Interactions
- CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
- CYP3A4 inducers (e.g., rifampin, carbamazepine)
- Warfarin
โก Moderate Interactions
- Clopidogrel
- Cisplatin
- Doxorubicin
โน๏ธ Minor Interactions
- Dexamethasone
- Diphenhydramine
๐ฝ๏ธ Food Interactions
Grapefruit juice (may increase exposure)
๐ท Alcohol Interaction
Avoid alcohol; may increase hepatotoxicity risk.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to docetaxel or polysorbate 80; severe hepatic impairment; neutropenia (<1500 cells/mmยณ); pregnancy.
๐ Monitoring Parameters
Complete blood count, liver function tests, renal function, vital signs, infusion reactions.
๐คฑ Lactation Safety
Contraindicated; excreted in breast milk.
๐ Overdose Management
Supportive care; monitor for myelosuppression, mucositis, and neuropathy.
โฐ Missed Dose
Do not double dose; contact physician for rescheduling.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for chemotere 120mg injection
View AllAlternative brands with exact same active ingredient (Docetaxel (120mg)):
-
docetere 120mg solvent for injectionDr Reddy's Laboratories Ltd โน29.50 99.8% CHEAPER
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daxotel 120mg injectionFresenius Kabi India Pvt Ltd โน30.00 99.8% CHEAPER
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solvent for docetaxel concentrate 120mg injectionDr Reddy's Laboratories Ltd โน95.00 99.3% CHEAPER
-
Relidoce 120mg InjectionReliance Formulation Pvt Ltd โน1,453.13 89.8% CHEAPER
-
docax 120mg injectionNeon Laboratories Ltd โน2,179.00 84.7% CHEAPER
-
docetax 120mg injectionCipla Ltd โน6,562.00 53.8% CHEAPER
-
innotubilin 120mg injectionInnova Formulations Pvt Ltd โน8,906.25 37.3% CHEAPER
-
taxocare 120mg injectionIntas Pharmaceuticals Ltd โน9,375.00 34% CHEAPER
-
Tubitere 120mg InjectionAlkem Laboratories Ltd โน9,960.94 29.9% CHEAPER
-
Taxewell 120mg InjectionGetwell Oncology Pvt Ltd โน11,250.00 20.8% CHEAPER
Medical Note: Always consult your doctor before switching medications.
โญ User Reviews
Good quality medicine. Satisfied with the outcome.
Good quality medicine. Satisfied with the outcome.
This medicine was effective for me. I followed the doctor's advice.
Good quality medicine. Satisfied with the outcome.
Helpful and effective medicine as per my experience. Always consult a doctor.