cglit 15mg tablet

4.6 (18 reviews)

Pioglitazone (15mg)

🏭 CMG Pharmaceuticals 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 22, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 22, 2026

What is cglit 15mg tablet used for?

Adglim P 15mg Tablet (Pioglitazone) is used to treat ANTI DIABETIC. It contains Pioglitazone (15mg), which Selective agonist at peroxisome proliferator-activated receptor-gamma (PPARγ), . Always consult your doctor before use. Take as prescribed.

Generic Name: Pioglitazone
Manufacturer: CMG Pharmaceuticals
Form: Allopathy
Pregnancy Category: C
Prescription Required: Yes

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 cglit 15mg tablet Uses & Benefits

Type 2 diabetes mellitus, Adjunct to diet and exercise

Off-label uses: Non-alcoholic steatohepatitis (NASH), Polycystic ovary syndrome (PCOS)

📋 Drug Information

Generic Name(s)	Pioglitazone
Brand Name	Adglim P 15mg Tablet
Manufacturer	CMG Pharmaceuticals
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	ANTI DIABETIC
Action Class	Thiazolidinedione(PPAR gamma agonist)
Route of Administration	Oral
Storage	Store at 20-25°C (68-77°F); protect from moisture and light.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed; peak plasma concentration achieved within 2 hours.

DistributionDistributes widely in body tissues; volume of distribution approximately 0.25 L/kg.

Protein Binding>99% bound to plasma proteins, primarily albumin.

MetabolismExtensively metabolized in the liver via CYP2C8 and CYP3A4 isoenzymes.

Half-Life3-7 hours (parent drug); metabolites have longer half-lives.

ExcretionPrimarily excreted in feces (55%) and urine (45%) as metabolites.

Bioavailability>80%

Onset of ActionWithin 2-4 weeks for glycemic control.

Peak Plasma Time2 hours

Duration of ActionUp to 24 hours

How It Works

Selective agonist at peroxisome proliferator-activated receptor-gamma (PPARγ), increasing insulin sensitivity in adipose tissue, skeletal muscle, and liver.

Mechanism Steps

1Binds to PPARγ receptors in adipose tissue, muscle, and liver.

2Activates PPARγ, leading to increased transcription of insulin-responsive genes.

3Enhances insulin sensitivity by promoting glucose uptake in peripheral tissues.

💡 How to Take cglit 15mg tablet

Follow your doctor's prescription exactly.

⚠️ Side Effects of cglit 15mg tablet

✅ Common Side Effects

Upper respiratory tract infection
Headache
Sinusitis
Myalgia
Weight gain

🚨 Serious Side Effects

Heart failure
Bladder cancer (possible)
Hepatotoxicity
Macular edema

⚠️ Rare Side Effects

Hypoglycemia
Bone fractures (women)
Anemia

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Gemfibrozil	Major	Increased pioglitazone exposure and risk of hypoglycemia
Rifampin	Major	Decreased pioglitazone efficacy
Insulin	Moderate	Increased risk of hypoglycemia
Sulfonylureas	Moderate	Additive hypoglycemic effect
NSAIDs	Moderate	Increased risk of fluid retention and edema

🚨 Major Interactions

CYP2C8 inhibitors (e.g., gemfibrozil)
CYP2C8 inducers (e.g., rifampin)

⚡ Moderate Interactions

Insulin
Sulfonylureas
NSAIDs

ℹ️ Minor Interactions

Oral contraceptives
Calcium channel blockers

🍽️ Food Interactions

No significant food interactions; can be taken with or without food.

🍷 Alcohol Interaction

May increase risk of hypoglycemia; avoid excessive alcohol.

🛡️ Safety & Warnings

🚫 Contraindications

NYHA Class III/IV heart failure, Active liver disease, Type 1 diabetes, Diabetic ketoacidosis

📊 Monitoring Parameters

Blood glucose, HbA1c, Liver function tests, Signs of fluid retention

🤱 Lactation Safety

Not recommended; excreted in milk in animal studies.

💊 Overdose Management

Supportive care; monitor blood glucose; may require dextrose infusion.

⏰ Missed Dose

Take as soon as remembered unless close to next dose; do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

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🔄 Substitutes for cglit 15mg tablet

View All

Alternative brands with exact same active ingredient (Pioglitazone (15mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Happy Patient Jul 10, 2026

Effective and reliable. Worked as expected.

Regular Customer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.