adizone 15mg tablet - Pioglitazone (15mg) medicine

Adizone 15mg Tablet - Uses, Price, Side Effects

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🏭 Parenteral Drugs India Ltd πŸ“¦ Varies by brand πŸ’Š Allopathy πŸ“… Updated: Jul 5, 2026
πŸ“‹ Prescription Required πŸ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jul 05, 2026

What is adizone 15mg tablet used for?

Adizone 15mg Tablet contains Pioglitazone, a thiazolidinedione that improves insulin sensitivity in muscle and fat tissues, and reduces glucose production in the liver. It is used along with diet and exercise to control high blood sugar in type 2 diabetes. It may be used alone or with other diabetes medications.

  • Generic Name: Pioglitazone
  • Manufacturer: Parenteral Drugs India Ltd
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
πŸ’‘ Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

πŸ’Š adizone 15mg tablet Uses & Benefits

Type 2 diabetes mellitus, Adjunct to diet and exercise

Off-label uses: Non-alcoholic steatohepatitis (NASH), Polycystic ovary syndrome (PCOS)

πŸ“‹ Drug Information

Generic Name(s)Pioglitazone
Brand NameAdglim P 15mg Tablet
ManufacturerParenteral Drugs India Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI DIABETIC
Action ClassThiazolidinedione(PPAR gamma agonist)
Route of AdministrationOral
StorageStore at 20-25Β°C (68-77Β°F); protect from moisture and light.
Shelf LifeAs per manufacturer

πŸ”¬ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed; peak plasma concentration achieved within 2 hours.
DistributionDistributes widely in body tissues; volume of distribution approximately 0.25 L/kg.
Protein Binding>99% bound to plasma proteins, primarily albumin.
MetabolismExtensively metabolized in the liver via CYP2C8 and CYP3A4 isoenzymes.
Half-Life3-7 hours (parent drug); metabolites have longer half-lives.
ExcretionPrimarily excreted in feces (55%) and urine (45%) as metabolites.
Bioavailability>80%
Onset of ActionWithin 2-4 weeks for glycemic control.
Peak Plasma Time2 hours
Duration of ActionUp to 24 hours

How It Works

Selective agonist at peroxisome proliferator-activated receptor-gamma (PPARΞ³), increasing insulin sensitivity in adipose tissue, skeletal muscle, and liver.

Mechanism Steps

1Binds to PPARΞ³ receptors in adipose tissue, muscle, and liver.
2Activates PPARΞ³, leading to increased transcription of insulin-responsive genes.
3Enhances insulin sensitivity by promoting glucose uptake in peripheral tissues.

πŸ’‘ How to Take adizone 15mg tablet

Follow your doctor's prescription exactly.

Dosage Timeline

πŸŒ… Morning βœ… β˜€οΈ Afternoon ❌ πŸŒ† Evening βœ… πŸŒ™ Night ❌

⚠️ Side Effects of adizone 15mg tablet

βœ… Common Side Effects

  • Upper respiratory tract infection
  • Headache
  • Sinusitis
  • Myalgia
  • Weight gain

🚨 Serious Side Effects

  • Heart failure
  • Bladder cancer (possible)
  • Hepatotoxicity
  • Macular edema

⚠️ Rare Side Effects

  • Hypoglycemia
  • Bone fractures (women)
  • Anemia

Consult your doctor if you experience any unusual symptoms.

πŸ”¬ Drug Interactions

⚠️ DrugSeverityEffect
Insulin Major Increased risk of hypoglycemia
Sulfonylureas Major Increased risk of hypoglycemia
Warfarin Moderate Decreased anticoagulant effect
Rifampin Moderate Decreased pioglitazone efficacy

🚨 Major Interactions

  • CYP2C8 inhibitors (e.g., gemfibrozil)
  • CYP2C8 inducers (e.g., rifampin)

⚑ Moderate Interactions

  • Insulin
  • Sulfonylureas
  • NSAIDs

ℹ️ Minor Interactions

  • Oral contraceptives
  • Calcium channel blockers

🍽️ Food Interactions

No significant food interactions; can be taken with or without food.

🍷 Alcohol Interaction

May increase risk of hypoglycemia; avoid excessive alcohol.

πŸ›‘οΈ Safety & Warnings

Liver
Low
Kidney
Low
Heart
Moderate
Pregnancy
Category C

🚫 Contraindications

NYHA Class III/IV heart failure, Active liver disease, Type 1 diabetes, Diabetic ketoacidosis

πŸ“Š Monitoring Parameters

Blood glucose, HbA1c, Liver function tests, Signs of fluid retention

🀱 Lactation Safety

Not recommended; excreted in milk in animal studies.

πŸ’Š Overdose Management

Supportive care; monitor blood glucose; may require dextrose infusion.

⏰ Missed Dose

Take as soon as remembered unless close to next dose; do not double dose.

πŸ‘¨β€βš•οΈ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Jul 05, 2026

πŸ”— View Profile

πŸ”„ Substitutes for adizone 15mg tablet

View All

Alternative brands with exact same active ingredient (Pioglitazone (15mg)):

Medical Note: Always consult your doctor before switching medications.

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