cevoric c 50mg injection
What is cevoric c 50mg injection used for?
Adcov 50mg Injection (Calcium Leucovorin) is used to treat BLOOD RELATED. It contains Calcium Leucovorin (50mg), which Leucovorin is a reduced form of folic acid that bypasses dihydrofolate reductase. Always consult your doctor before use. Take as prescribed.
- Generic Name: Calcium Leucovorin
- Manufacturer: Health Biotech Limited
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ cevoric c 50mg injection Uses & Benefits
Rescue therapy after high-dose methotrexate; enhancement of fluorouracil efficacy in colorectal cancer; treatment of folate deficiency; adjunct in toxoplasmosis.
Off-label uses: Treatment of hyperhomocysteinemia, Prevention of neural tube defects
๐ Drug Information
| Generic Name(s) | Calcium Leucovorin |
| Brand Name | Adcov 50mg Injection |
| Manufacturer | Health Biotech Limited |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | BLOOD RELATED |
| Action Class | Cytoprotective agents- methotrexate |
| Route of Administration | Intravenous, intramuscular |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from light. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Leucovorin is a reduced form of folic acid that bypasses dihydrofolate reductase inhibition, providing exogenous folate for DNA synthesis and repair.
Mechanism Steps
๐ก How to Take cevoric c 50mg injection
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of cevoric c 50mg injection
โ Common Side Effects
- Nausea
- Vomiting
- Diarrhea
- Stomatitis
- Rash
๐จ Serious Side Effects
- Allergic reactions
- Seizures
- Thrombocytosis
- Hypocalcemia
โ ๏ธ Rare Side Effects
- Anaphylaxis
- Leukopenia
- Thrombocytopenia
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Fluorouracil | Major | Enhanced cytotoxicity and toxicity of fluorouracil. |
| Methotrexate | Major | Reverses methotrexate toxicity; used as rescue therapy. |
| Trimethoprim | Major | Antagonizes antimicrobial effect of trimethoprim. |
| Pyrimethamine | Major | Reduces efficacy of pyrimethamine in toxoplasmosis. |
| Phenytoin | Moderate | Decreased phenytoin levels. |
| Primidone | Moderate | Decreased primidone levels. |
| Barbiturates | Moderate | Decreased barbiturate levels. |
| Sulfonamides | Moderate | Possible decreased efficacy of sulfonamides. |
| Oral contraceptives | Minor | Possible reduced contraceptive efficacy. |
| Antacids | Minor | Possible decreased absorption of leucovorin. |
| Cholestyramine | Minor | Possible decreased absorption of leucovorin. |
๐จ Major Interactions
- Fluorouracil
- Methotrexate
- Trimethoprim
- Pyrimethamine
โก Moderate Interactions
- Phenytoin
- Primidone
- Barbiturates
- Sulfonamides
โน๏ธ Minor Interactions
- Oral contraceptives
- Antacids
- Cholestyramine
๐ฝ๏ธ Food Interactions
No significant food interactions.
๐ท Alcohol Interaction
No known interaction.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to leucovorin or any component; pernicious anemia or other megaloblastic anemias due to vitamin B12 deficiency.
๐ Monitoring Parameters
Serum methotrexate levels (if used as rescue), complete blood count, renal function, liver function.
๐คฑ Lactation Safety
Excreted in breast milk; use with caution.
๐ Overdose Management
No specific antidote; supportive care; monitor for electrolyte imbalances.
โฐ Missed Dose
Administer as soon as remembered; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for cevoric c 50mg injection
View AllAlternative brands with exact same active ingredient (Calcium Leucovorin (50mg)):
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neovorin injectionNeon Laboratories Ltd โน68.00 72.8% CHEAPER
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leucovorin injectionDabur India Ltd โน234.38 6.2% CHEAPER
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nyrin 50mg injectionVhb Life Sciences Inc โน240.00 4% CHEAPER
-
adcov 50mg injectionAdley Formulations โน250.00 SAME PRICE
-
leutero 50mg injectionHetero Drugs Ltd โน250.00 SAME PRICE
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shilstine 50mg injectionShilpa Medicare Ltd โน265.00 6% COSTLIER
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recovorin 50mg injectionZydus Cadila โน265.62 6.2% COSTLIER
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lucal 50mg injectionCelon Laboratories Ltd โน266.66 6.7% COSTLIER
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leucowel injectionGetwell Pharmaceutical Pvt Ltd โน280.00 12% COSTLIER
-
calcium leucovorin 50mg injectionSamarth Life Sciences Pvt Ltd โน288.12 15.2% COSTLIER
Medical Note: Always consult your doctor before switching medications.
โญ User Reviews
Effective and reliable. Worked as expected.
Good quality medicine. Satisfied with the outcome.
Found this to be a helpful product. Good results.
This medicine was effective for me. I followed the doctor's advice.
Helpful and effective medicine as per my experience. Always consult a doctor.