cetvent br syrup - Terbutaline (1.25mg/5ml) + Bromhexine (4mg/5ml) medicine

Coughcin Br Syrup: Complete Medicine Guide

No reviews yet
🏭 Mikail Pharma Private Limited 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 27, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for the combination in productive cough; individual components have well-established evidence.
Reviewed by
SaathiMed Expert Panel | Oct 27, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or shortness of breath
  • Chest pain or palpitations
  • Severe allergic reaction (rash, itching, swelling of face/lips/throat)
  • Blood in cough or sputum
  • High fever with chills
  • Yellowing of skin or eyes (jaundice)
  • Severe dizziness or fainting
  • Uncontrollable shaking or tremor

If experiencing severe symptoms, call emergency services immediately.

What is cetvent br syrup used for?

This medicine is a combination of terbutaline and bromhexine used to treat productive cough by relaxing airways and thinning mucus. It is available as a syrup and is taken orally, usually 5-10 ml two to three times daily as prescribed.

  • Generic Name: Terbutaline + Bromhexine
  • Manufacturer: Mikail Pharma Private Limited
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 cetvent br syrup के बारे में (Hindi Summary)

उपयोग: यह दवा टर्ब्यूटलाइन और ब्रोमहेक्सिन का संयोजन है, जिसका उपयोग बलगम वाली खांसी के इलाज के लिए किया जाता है। यह श्वसन मार्ग की मांसपेशियों को आराम देकर सांस लेना आसान बनाती है और गाढ़े बलगम को पतला करके बाहर निकालने में मदद करती है। यह दवा ब्रोंकाइटिस और अन्य श्वसन संबंधी समस्याओं में प्रभावी है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में हाथ-पैर कांपना, घबराहट, सिरदर्द, चक्कर आना, जी मिचलाना और पेट खराब होना शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि आपको सांस लेने में कठिनाई, दिल की धड़कन तेज होना, या चेहरे पर सूजन हो, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी सभी स्वास्थ्य समस्याओं और दवाओं के बारे में बताएं। यदि आपको हृदय रोग, उच्च रक्तचाप, मधुमेह या थायरॉइड की समस्या है, तो सावधानी बरतें। गर्भावस्था या स्तनपान के दौरान डॉक्टर की सलाह के बिना इसका उपयोग न करें। शराब का सेवन न करें। दवा लेते समय वाहन चलाने से बचें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 cetvent br syrup Uses & Benefits

[{"condition":"Productive cough associated with acute bronchitis","description":"Helps to loosen thick mucus and relax airways, making it easier to cough out secretions and breathe more comfortably.","evidence":"Well-established"},{"condition":"Productive cough associated with chronic bronchitis","description":"Used to manage chronic mucus hypersecretion and bronchospasm in conditions like chronic obstructive pulmonary disease (COPD) exacerbations.","evidence":"Well-established"},{"condition":"Cough with bronchospasm","description":"Provides symptomatic relief when cough is accompanied by mild airway constriction, due to the bronchodilator action of terbutaline.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Asthma with thick mucus","description":"Sometimes prescribed off-label to help with mucus clearance in asthma patients, though inhaled therapies are preferred.","evidence":"Limited"}]

Primary treatment for: Productive cough associated with bronchitis

Also treats: Chronic obstructive pulmonary disease (COPD) with mucus, Asthma with thick mucus

📋 Drug Information

Generic Name(s)Terbutaline + Bromhexine
Brand NameAskafex TR Suspension
ManufacturerMikail Pharma Private Limited
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassBronchodilator + Mucolytic
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep the bottle tightly closed. Do not freeze.
Shelf Life24 months from the date of manufacture, or as indicated on the packaging.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always shake the bottle well before measuring the dose to ensure uniform distribution of the medicine.
2
Use a proper measuring cup or spoon to avoid inaccurate dosing; household spoons vary in size.
3
Take this medicine with food or milk if it causes stomach upset.
4
Avoid driving or operating heavy machinery until you know how this medicine affects you, as it can cause dizziness or tremor.
5
Do not take this medicine for more than the prescribed duration without consulting your doctor.
6
If you have a history of heart disease, diabetes, or thyroid problems, inform your doctor before starting this medicine.
7
Keep track of your symptoms; if cough persists beyond 7 days or worsens, contact your doctor.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Productive cough with thick mucus
This medicine is commonly prescribed for this.
Likely Use
❌
Dry cough
This medicine is not effective for dry cough.
Not Primary
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
✅
Wheezing with cough
The bronchodilator component may help with wheezing.
Likely Use

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionTerbutaline is well absorbed from the gastrointestinal tract after oral administration, though it undergoes some first-pass metabolism. Bromhexine is also rapidly absorbed from the gastrointestinal tract. The exact bioavailability of the combination in this syrup form is not established from the available information.
DistributionTerbutaline distributes widely into body tissues, including the lungs. It crosses the placenta and is excreted in breast milk. Bromhexine also distributes into tissues and can cross the blood-brain barrier to some extent. Protein binding information for both agents is not established from the available information.
Protein BindingNot established from the available information.
MetabolismTerbutaline is metabolized in the liver, primarily by conjugation to inactive sulfate and glucuronide metabolites. Bromhexine is extensively metabolized in the liver, mainly by first-pass metabolism, to several metabolites. The exact metabolic pathways for the combination are not fully established from the available information.
Half-LifeThe elimination half-life of terbutaline is approximately 3 to 4 hours. The elimination half-life of bromhexine is not well established but is thought to be around 1 to 2 hours. These values may vary based on individual factors.
ExcretionTerbutaline and its metabolites are primarily excreted in the urine. Bromhexine and its metabolites are also excreted mainly in the urine. The exact proportions are not established from the available information.
BioavailabilityThe oral bioavailability of terbutaline is approximately 10-15% due to first-pass metabolism. The bioavailability of bromhexine is not well established but is considered to be low due to extensive first-pass metabolism. The bioavailability of the combination in this syrup is not established from the available information.
Onset of ActionThe onset of action for terbutaline after oral administration is typically within 30 to 60 minutes. The onset of action for bromhexine's mucolytic effect may take longer, often within 1 to 2 hours. The exact onset for this combination product is not established from the available information.
Peak Plasma TimePeak plasma concentrations of terbutaline are usually reached within 2 to 4 hours after oral administration. The peak plasma time for bromhexine is not well established. The exact peak plasma time for this combination is not established from the available information.
Duration of ActionThe bronchodilator effect of terbutaline lasts for about 4 to 6 hours. The mucolytic effect of bromhexine may last for several hours. The exact duration of action for this combination product is not established from the available information.

How It Works

This medicine combines two active ingredients with complementary actions. Terbutaline is a selective beta-2 adrenergic receptor agonist that binds to beta-2 receptors on the smooth muscle cells of the airways, leading to relaxation and bronchodilation. Bromhexine is a mucolytic agent that works by breaking down the structure of mucus, reducing its viscosity and making it easier to expel. Together, they help to open the airways and clear mucus, providing relief from cough and breathing difficulty.

Mechanism Steps

1
Terbutaline binds to beta-2 receptors: Terbutaline selectively binds to beta-2 adrenergic receptors located on the surface of bronchial smooth muscle cells.
2
Activation of intracellular signaling: Binding triggers the activation of adenylate cyclase, which increases cyclic AMP (cAMP) levels inside the cell.
3
Bronchial smooth muscle relaxation: Elevated cAMP leads to relaxation of the smooth muscle, causing the airways to widen and improving airflow.
4
Bromhexine acts on mucus: Bromhexine reduces the viscosity of mucus by breaking down its structure, making it less sticky and easier to cough up.
5
Enhanced mucociliary clearance: The combined effects lead to easier expectoration of mucus and relief from cough associated with thick secretions.

💡 How to Take cetvent br syrup

Strength: Each 5 ml of syrup contains Terbutaline 1.25 mg and Bromhexine 4 mg.

1Shake the bottle well before each use.
2Use a measuring cup or spoon to measure the exact dose prescribed.
3Take the medicine orally, with or without food. Taking it with food may reduce stomach upset.
4Swallow the syrup; do not chew or crush.
5Follow the prescribed schedule and do not exceed the recommended dose.
6After use, close the bottle tightly and store as directed.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 5-10 ml (one to two teaspoons) taken two to three times a day, or as directed by your doctor. The dose may vary depending on the severity of your condition and your response to treatment. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine, especially cardiovascular effects such as increased heart rate and tremor. Use with caution and start with a lower dose as directed by a doctor. Dose must be individualized by a qualified clinician based on renal and hepatic function.
Renal ImpairmentIn patients with renal impairment, dose adjustment may be necessary. Consult your doctor for appropriate dosing. Dose must be individualized by a qualified clinician based on renal function.
Hepatic ImpairmentIn patients with hepatic impairment, dose adjustment may be necessary. Consult your doctor for appropriate dosing. Dose must be individualized by a qualified clinician based on hepatic function.
Maximum Daily DoseThe maximum recommended daily dose is 30 ml (6 teaspoons) per day, or as directed by your doctor. Do not exceed the prescribed dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Caffeine
Limit
May increase nervousness and heart rate.
Alcohol
Avoid
Increases drowsiness and cardiovascular effects.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of cetvent br syrup

✅ Common Side Effects

Tremor (shakiness of hands) (Common (5-10%))
Usually resolves on its own. If persistent or bothersome, consult your doctor.
Nervousness or restlessness (Common (5-10%))
Try to relax and avoid caffeine. Consult doctor if severe.
Headache (Common (5-10%))
Rest and stay hydrated. Consult doctor if headache persists.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you feel normal.
Nausea or stomach upset (Common (5-10%))
Take with food or milk to reduce stomach irritation.
Increased heart rate (palpitations) (Common (5-10%))
If palpitations are persistent or accompanied by chest pain, seek medical attention.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience rash, itching, swelling of face/lips/throat, or difficulty breathing.
Irregular heartbeat (arrhythmia) (Rare (<0.1%))
Contact your doctor immediately if you feel palpitations, chest pain, or shortness of breath.
Severe bronchospasm (worsening breathing) (Rare (<0.1%))
Stop the medicine and seek emergency medical help if your breathing becomes more difficult.
Hypokalemia (low potassium levels) (Rare (<0.1%))
Report muscle weakness, cramps, or palpitations to your doctor. Blood tests may be needed.

⚠️ Rare Side Effects

Sleep disturbances
Consult your doctor if sleep problems persist.
Muscle cramps
Stay hydrated and consult your doctor if cramps are severe.
Changes in taste
Usually temporary. Consult doctor if it bothers you.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Propranolol Major
MAOIs Major
Tricyclic antidepressants Major
Furosemide Moderate
Corticosteroids Moderate
Theophylline Moderate
Anticholinergics Minor

🚨 Major Interactions

  • Non-selective beta-blockers (e.g., propranolol)
  • Monoamine oxidase inhibitors (MAOIs)
  • Tricyclic antidepressants

⚡ Moderate Interactions

  • Diuretics (e.g., furosemide)
  • Corticosteroids
  • Xanthine derivatives (e.g., theophylline)

🍷 Alcohol Interaction

Alcohol should be avoided while taking this medicine. It can increase drowsiness, dizziness, and the risk of other central nervous system side effects. It may also exacerbate cardiovascular effects such as increased heart rate.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to terbutaline, bromhexine, or any component of the formulation","Severe cardiovascular disease, including arrhythmias and severe coronary insufficiency","Uncontrolled hypertension","Hyperthyroidism","Diabetes mellitus (uncontrolled)","Severe hepatic or renal impairment","Pregnancy (especially first trimester) unless clearly needed","Breastfeeding"]

⚠️ Warnings & Precautions

["Use with caution in patients with cardiovascular disease, including coronary insufficiency, arrhythmias, and hypertension.","May cause tremor, nervousness, and increased heart rate; advise patients to avoid driving if affected.","Use with caution in patients with diabetes, as terbutaline may increase blood glucose levels.","Use with caution in patients with hyperthyroidism, as terbutaline may exacerbate symptoms.","May cause hypokalemia; monitor potassium levels, especially with concomitant use of diuretics or corticosteroids.","Not recommended for children under 2 years of age unless prescribed by a pediatrician.","Do not exceed the recommended dose or duration of treatment without medical advice.","If symptoms persist or worsen, consult a doctor."]

🤱 Lactation Safety

Terbutaline is excreted in breast milk and may cause side effects in a nursing infant. Bromhexine is also likely to be excreted in breast milk. This medicine is not recommended during breastfeeding unless the potential benefit outweighs the risk. Consult your doctor before using this medicine while breastfeeding.

💊 Overdose Management

Overdose of this medicine may cause symptoms such as severe tremor, palpitations, chest pain, dizziness, nausea, vomiting, and hypotension. In case of overdose, seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if ingestion is recent. Monitor vital signs and electrolytes.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Before taking this medicine, inform your doctor if you have heart disease, high blood pressure, diabetes, thyroid problems, or a history of seizures. Do not take this medicine if you are allergic to terbutaline, bromhexine, or any other ingredients. This medicine may cause dizziness or drowsiness; avoid driving or operating heavy machinery until you know how it affects you. Do not drink alcohol while taking this medicine, as it can increase drowsiness and other side effects. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Do not share this medicine with others, even if they have similar symptoms. Keep out of reach of children. Do not exceed the prescribed dose or duration of treatment. If your cough does not improve within a few days or if you develop a fever, rash, or difficulty breathing, stop the medicine and contact your doctor immediately.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the cardiovascular and central nervous system effects of this medicine. Use with caution, starting at a lower dose. Monitor heart rate, blood pressure, and for signs of tremor or dizziness.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. It is not recommended during pregnancy unless clearly needed. Discuss alternative treatments if you are trying to conceive.

🏥 Post-Surgery Considerations

If you have recently undergone surgery, inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with certain anesthetic agents and affect heart rate and blood pressure.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine before any dental procedure. It may cause dry mouth or interact with local anesthetics containing epinephrine, potentially increasing heart rate.

💚 Lifestyle Tips for Better Results

🏃
Stay well hydrated to help thin mucus.
🥗
Use a humidifier to add moisture to the air, which can ease coughing.
😴
Avoid smoking and exposure to secondhand smoke.
💧
Get plenty of rest to help your body recover.
🧘
Practice good hand hygiene to prevent infections.
🌞
Avoid known allergens that trigger your cough.

🏋️ Exercise Considerations

This medicine may cause dizziness, tremor, or increased heart rate. Avoid strenuous exercise until you know how the medicine affects you. Light activity like walking may be fine, but consult your doctor before resuming intense workouts.

🥗 Diet Recommendations

Drink warm fluids like herbal tea or soup to soothe your throat.
Include honey in warm water to help with cough (not for infants under 1 year).
Avoid cold drinks and ice cream, which may worsen cough.
Eat a balanced diet rich in vitamins and minerals to support immunity.
Limit caffeine intake as it may increase nervousness.

💼 Impact on Daily Work & Life

This medicine can cause dizziness, drowsiness, or tremor, which may affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It is advisable to inform your employer if your job involves operating heavy machinery.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if your cough does not improve within 7 days, if it worsens, or if you develop new symptoms such as fever, rash, or difficulty breathing. Do not stop abruptly if you have been taking it for a long time without consulting your doctor.

📅 Long-Term Use Effects

Long-term use of this medicine should be under medical supervision. Prolonged use of terbutaline may lead to tolerance and reduced effectiveness. Regular monitoring of heart rate, blood pressure, and potassium levels may be required. Bromhexine is generally well-tolerated for short-term use. Do not use this medicine for extended periods without consulting your doctor.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Steam inhalation

Inhaling steam can help loosen mucus and soothe airways.

Evidence: Limited
Saline nasal irrigation

Helps clear nasal congestion and post-nasal drip.

Evidence: Moderate
Honey and warm fluids

Can soothe throat and reduce cough frequency.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, if you are due for a vaccination, inform your healthcare provider that you are taking this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription in case you need to show it at customs or to a healthcare provider. Store it at room temperature and protect it from extreme heat or direct sunlight. If you are crossing time zones, adjust your dosing schedule gradually, but consult your doctor for specific advice. Always pack enough medicine for your entire trip and a few extra days in case of delays.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with acute bronchitis
He was prescribed this medicine for a productive cough with thick mucus. After taking it as directed for 5 days, he noticed significant relief in chest congestion and easier breathing. He experienced mild hand tremors initially, which subsided after a few days.
💡 Lesson: Taking the medicine as prescribed and reporting side effects to the doctor helps in effective management.
👤 A 50-year-old woman with chronic bronchitis
She used this medicine during exacerbations of chronic bronchitis. It helped loosen mucus and reduce cough, making it easier to expectorate. She was advised to monitor her heart rate due to a history of hypertension.
💡 Lesson: Patients with underlying heart conditions should use this medicine with caution and regular monitoring.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start to feel relief from cough and congestion within 30 to 60 minutes after taking a dose, but the full effect may take a few hours. Consistent use as prescribed will provide the best results.

Q: Can I take this medicine with other cough medicines?

A: Do not take other cough medicines without consulting your doctor, as they may contain overlapping ingredients or interact with this medicine.

Q: Is it safe to take during pregnancy?

A: This medicine is not recommended during pregnancy unless clearly needed. Consult your doctor if you are pregnant or planning to become pregnant.

Q: What should I do if I experience side effects?

A: Mild side effects like tremor or nausea usually go away. If you experience severe or persistent side effects, contact your doctor immediately.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my heart?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for cetvent br syrup

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure any type of cough.
    Fact: This medicine is specifically for productive cough with thick mucus. It is not effective for dry cough or cough due to other causes.
  • Myth: It is safe to take without a prescription.
    Fact: This is a prescription medicine. It should only be taken under a doctor's supervision due to potential side effects and interactions.
  • Myth: More medicine means faster relief.
    Fact: Taking more than the prescribed dose can increase the risk of side effects and does not provide faster relief.

🔄 Alternative Options

Generic Alternatives

  • Terbutaline + Bromhexine syrup (generic)

Brand Alternatives

  • Coughcin BR Syrup

📊 Comparison with Similar Medicines

[{"medicine":"This medicine (Terbutaline + Bromhexine)","composition":"Terbutaline 1.25mg/5ml + Bromhexine 4mg/5ml","uses":"Productive cough with bronchospasm","notes":"Combines bronchodilator and mucolytic."},{"medicine":"Ambroxol + Terbutaline","composition":"Ambroxol 15mg/5ml + Terbutaline 1.25mg/5ml","uses":"Productive cough","notes":"Ambroxol is a mucolytic similar to bromhexine."},{"medicine":"Guaifenesin + Terbutaline","composition":"Guaifenesin 50mg/5ml + Terbutaline 1.25mg/5ml","uses":"Productive cough","notes":"Guaifenesin is an expectorant."}]

😊 Was this information helpful?

Browse Medicines A-Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory