Abokof BR Syrup: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Chest pain or irregular heartbeat
- Severe difficulty breathing or worsening of breathing
- Swelling of face, lips, or throat
- Severe dizziness or fainting
- Blood in cough or vomit
- Persistent high fever
- Yellowing of skin or eyes
If experiencing severe symptoms, call emergency services immediately.
What is kofkil syrup used for?
This medicine is a combination syrup containing terbutaline (a bronchodilator) and bromhexine (a mucolytic). It is used to relieve cough with wheezing and thick mucus by relaxing airways and thinning secretions. It is for short-term use under medical supervision.
- Generic Name: Terbutaline (1.25mg/5ml) + Bromhexine (4mg/5ml)
- Manufacturer: Unilite Medicare Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 kofkil syrup के बारे में (Hindi Summary)
उपयोग: यह दवा टर्ब्यूटलीन और ब्रोमहेक्सिन का संयोजन है। यह बलगम वाली खांसी, घरघराहट और सांस लेने में कठिनाई में राहत देती है। टर्ब्यूटलीन श्वास नलियों को फैलाता है और ब्रोमहेक्सिन बलगम को पतला करता है जिससे खांसी में आसानी होती है। यह दवा डॉक्टर की सलाह पर ही लेनी चाहिए।
साइड इफेक्ट्स: आम दुष्प्रभावों में हाथ-पैर कांपना, घबराहट, सिरदर्द, धड़कन तेज होना और जी मिचलाना शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर सांस लेने में तकलीफ, सीने में दर्द, या चेहरे पर सूजन हो तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक से ज्यादा न लें। हर बार उपयोग से पहले बोतल को अच्छी तरह हिलाएं और मापने वाले कप से सही मात्रा लें। अगर आपको दिल की बीमारी, उच्च रक्तचाप, मधुमेह, थायरॉइड या गुर्दे/जिगर की समस्या है तो डॉक्टर को बताएं। बच्चों की पहुंच से दूर रखें।
💊 kofkil syrup Uses & Benefits
[{"condition":"Productive cough with bronchospasm","description":"Relieves cough and helps clear mucus by relaxing airways and thinning secretions.","evidence":"Well-established"},{"condition":"Acute bronchitis","description":"Used for short-term relief of cough and wheezing associated with acute bronchitis.","evidence":"Moderate"},{"condition":"Chronic bronchitis","description":"May help manage symptoms in chronic bronchitis, but not for acute severe exacerbations.","evidence":"Limited"}]
Off-label uses: []
Primary treatment for: Productive cough with bronchospasm
Also treats: Acute bronchitis, Chronic bronchitis, Asthma (adjunctive), COPD (adjunctive)
📋 Drug Information
| Generic Name(s) | Terbutaline (1.25mg/5ml) + Bromhexine (4mg/5ml) |
| Brand Name | kofkil syrup |
| Manufacturer | Unilite Medicare Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. Do not freeze. Keep the bottle tightly closed. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Terbutaline acts as a selective beta-2 adrenergic receptor agonist, which relaxes bronchial smooth muscle, leading to bronchodilation. Bromhexine increases serous bronchial secretion and reduces mucus viscosity by depolymerizing mucopolysaccharide fibers, thereby aiding in the clearance of mucus from the respiratory tract.
Mechanism Steps
💡 How to Take kofkil syrup
Strength: Each 5 ml contains Terbutaline 1.25 mg and Bromhexine 4 mg.
Dosage Information
| Adult Dosage | The usual adult dose is 5-10 ml (1-2 teaspoons) three times a day, or as directed by your physician. Dose may vary based on the severity of the condition and patient response. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children. |
| Elderly Dosage | Elderly patients may be more sensitive to the cardiovascular effects of terbutaline. Use with caution and start with a lower dose as prescribed by a doctor. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose adjustment may be necessary based on clinical response and renal function. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose adjustment may be necessary based on clinical response and hepatic function. |
| Maximum Daily Dose | The maximum recommended daily dose is 30 ml (6 teaspoons) in divided doses, but this may vary based on medical advice. Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of kofkil syrup
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Propranolol | Major | |
| MAOIs | Major | |
| Tricyclic antidepressants | Major | |
| Furosemide | Moderate | |
| Corticosteroids | Moderate | |
| Digoxin | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Non-selective beta-blockers (e.g., propranolol)
- Monoamine oxidase inhibitors (MAOIs)
- Tricyclic antidepressants
⚡ Moderate Interactions
- Diuretics (e.g., furosemide)
- Corticosteroids
- Digoxin
🍷 Alcohol Interaction
Alcohol may increase the risk of dizziness, drowsiness, and cardiovascular side effects. It is advisable to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to terbutaline, bromhexine, or any component of the formulation","Severe cardiac disease, including arrhythmias","Uncontrolled hypertension","Hyperthyroidism","First trimester of pregnancy (relative contraindication)"]
⚠️ Warnings & Precautions
["Use with caution in patients with cardiovascular disorders, including coronary insufficiency, arrhythmias, and hypertension.","May cause tremor, nervousness, or restlessness; avoid driving or operating machinery if affected.","Use with caution in patients with diabetes mellitus; may cause hyperglycemia.","Use with caution in patients with hyperthyroidism; may exacerbate symptoms.","Not for use in acute severe asthma attacks; seek emergency care.","Do not exceed recommended dose; excessive use may cause cardiac side effects.","Use with caution in elderly patients and those with renal or hepatic impairment."]
🤱 Lactation Safety
Terbutaline is excreted in breast milk in small amounts. Bromhexine is also excreted in breast milk. Consult your doctor before using this medicine while breastfeeding; it may be considered if benefits outweigh risks.
💊 Overdose Management
Overdose may cause severe tachycardia, palpitations, tremor, nausea, vomiting, and hypotension. Seek immediate medical attention. Treatment is supportive and symptomatic. Monitor cardiac and respiratory status. There is no specific antidote.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose. Shake the bottle well before each use and measure with a proper measuring cup or spoon. Avoid driving or operating heavy machinery if you feel dizzy or shaky. Inform your doctor if you have heart disease, high blood pressure, diabetes, thyroid problems, or kidney or liver disease. Do not take this medicine for longer than your doctor advises. Keep out of reach of children. Store at room temperature, away from direct sunlight and moisture.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more susceptible to cardiovascular side effects such as palpitations and arrhythmias. Use with caution and lower doses may be required. Monitor heart rate and blood pressure regularly.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. It is not recommended during the first trimester unless clearly needed. Discuss potential risks and benefits with your healthcare provider.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist if you are taking this medicine before surgery. It may interact with anesthetic agents and affect heart rate and blood pressure.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, as it may cause dry mouth or interact with medications used during dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise if you experience dizziness, tremor, or palpitations. Light activity like walking may be beneficial, but consult your doctor before starting any exercise routine.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, tremor, or nervousness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It is advisable to take rest if you feel unwell.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if your symptoms do not improve within 7 days, if they worsen, or if you experience any serious side effects. Do not stop abruptly if you have been taking it for a long time without medical advice.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended without medical supervision. Prolonged use of terbutaline may lead to tolerance, increased heart rate, and tremors. Bromhexine is generally well tolerated but long-term effects are not well studied. Regular monitoring of heart rate, blood pressure, and potassium levels may be required if used for extended periods.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Helps loosen mucus and relieve congestion.
Evidence: Well-establishedCan help clear nasal passages and reduce postnasal drip.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are due for a vaccine, inform your healthcare provider about all medicines you are taking.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If traveling across time zones, adjust dosing times gradually as advised by your doctor. Keep it in your carry-on luggage to avoid temperature extremes in checked baggage. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts working within 30 minutes to 1 hour after taking a dose.
A: Do not take with other cough syrups without consulting your doctor, as it may lead to overdose or interactions.
A: Pediatric dosing is not established. Consult a pediatrician before giving this medicine to children.
🤔 Common Patient Concerns
🔄 Substitutes for kofkil syrup
View AllAlternative brands with exact same active ingredient:
-
zycof syrupHos & Ins ₹39.38 6.2% CHEAPER
-
flolin syrupHi Tech Pharmaceuticals Pvt Ltd ₹43.61 3.8% COSTLIER
-
koflatch-x syrupLiza Life Sciences ₹48.75 16.1% COSTLIER
-
coughcin br syrupSBM Pharmaceuticals ₹51.56 22.8% COSTLIER
-
kufwaq-br syrupRexit Pharmaceutical ₹60.94 45.1% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure any type of cough.
Fact: This medicine is specifically for productive cough with bronchospasm. It is not effective for dry cough or cough due to other causes. - Myth: It is safe to take this medicine for a long time.
Fact: This medicine is intended for short-term use. Prolonged use should be under medical supervision due to potential side effects.
🔄 Alternative Options
Generic Alternatives
- Terbutaline + Bromhexine syrup (generic)