cetogat 400mg tablet - Gatifloxacin (400mg) medicine

cetogat 400mg tablet

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🏭 Artel Laboratories 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 25, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Reviewed by
SaathiMed Expert Panel | Sep 25, 2026

What is cetogat 400mg tablet used for?

This medicine contains Gatifloxacin (400mg) and is used to treat GASTRO INTESTINAL. Inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication and transcription.. Always consult your doctor before use.

  • Generic Name: Gatifloxacin
  • Manufacturer: Artel Laboratories
  • Form: Allopathy
  • Pregnancy Category: Category C
  • Prescription Required: Yes
💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 cetogat 400mg tablet Uses & Benefits

Treatment of acute bacterial exacerbation of chronic bronchitis, community-acquired pneumonia, acute sinusitis, uncomplicated urinary tract infections, and pyelonephritis.

Off-label uses: Bacterial prostatitis, Gonorrhea, Traveler's diarrhea

📋 Drug Information

Generic Name(s)Gatifloxacin
Brand NameAbgate
ManufacturerArtel Laboratories
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassQuinolones/ Fluroquinolones
Route of AdministrationOral
StorageStore at 20-25°C (68-77°F); protect from light and moisture.
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionRapidly absorbed after oral administration; bioavailability approximately 96%.
DistributionWidely distributed into tissues and fluids; high concentrations in lung, sinus, and urinary tract.
Protein BindingApproximately 20% bound to plasma proteins.
MetabolismMinimal hepatic metabolism; primarily excreted unchanged.
Half-Life7-14 hours
ExcretionPrimarily excreted unchanged in urine (70-80%) and feces.
Bioavailability96%
Onset of ActionRapid; within 1-2 hours.
Peak Plasma Time1-2 hours
Duration of ActionApproximately 12-24 hours

How It Works

Inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication and transcription.

Mechanism Steps

1Gatifloxacin enters bacterial cell via porin channels.
2Binds to DNA gyrase (topoisomerase II) and topoisomerase IV.
3Inhibits supercoiling and relaxation of bacterial DNA.
4Prevents DNA replication, transcription, and repair.
5Leads to bacterial cell death.

💡 How to Take cetogat 400mg tablet

Follow your doctor's prescription exactly.

⚠️ Side Effects of cetogat 400mg tablet

✅ Common Side Effects

Nausea
Diarrhea
Headache
Dizziness
Insomnia

🚨 Serious Side Effects

Tendon rupture
QT prolongation
Hypoglycemia
Seizures
Peripheral neuropathy

⚠️ Rare Side Effects

Anaphylaxis
Stevens-Johnson syndrome
Hepatotoxicity
Clostridium difficile colitis

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major Increased bleeding risk
Insulin Major Enhanced hypoglycemic effect
NSAIDs Moderate Increased risk of CNS stimulation and seizures
Antacids (Mg/Al) Moderate Reduced absorption of gatifloxacin
Corticosteroids Moderate Increased risk of tendon rupture

🚨 Major Interactions

  • Class IA antiarrhythmics
  • Class III antiarrhythmics
  • Insulin
  • Oral hypoglycemics

⚡ Moderate Interactions

  • NSAIDs
  • Corticosteroids
  • Antacids containing magnesium or aluminum
  • Sucralfate
  • Iron supplements
  • Zinc supplements

🍷 Alcohol Interaction

Avoid alcohol; may increase risk of CNS effects and hypoglycemia.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to gatifloxacin or any fluoroquinolone; history of tendon disorders; epilepsy; QT prolongation; uncorrected hypokalemia; concurrent use with Class IA or III antiarrhythmics.

🤱 Lactation Safety

Excreted in breast milk; avoid use or discontinue breastfeeding.

💊 Overdose Management

Supportive care; monitor ECG for QT prolongation; no specific antidote; hemodialysis may remove drug.

⏰ Missed Dose

Take as soon as remembered unless near next dose; do not double dose.

🔄 Substitutes for cetogat 400mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

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