Actidol-DP Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in vomit or stool
- Severe abdominal pain
- Chest pain or palpitations
- Difficulty breathing or swelling of face/lips/throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual muscle stiffness or tremors
If experiencing severe symptoms, call emergency services immediately.
What is cetdom 10mg/325mg tablet used for?
This medicine is a combination of Domperidone and Paracetamol used to treat nausea, vomiting, and mild to moderate pain or fever. It works by blocking nausea signals in the brain and reducing pain and fever centrally. It should be taken as prescribed, usually before meals, and not for more than 7 days without medical advice.
- Generic Name: Domperidone + Paracetamol
- Manufacturer: Biophar Lifesciences Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 cetdom 10mg/325mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा डोम्पेरिडोन और पैरासिटामोल का संयोजन है, जिसका उपयोग मतली, उल्टी और हल्के से मध्यम दर्द या बुखार के इलाज के लिए किया जाता है। यह पेट की गति को सुधारती है और मस्तिष्क में मतली के संकेतों को रोकती है। यह दवा आमतौर पर भोजन से पहले ली जाती है और डॉक्टर के निर्देशानुसार ही लेनी चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मुँह सूखना, सिरदर्द, नींद आना और पेट में हल्की परेशानी शामिल हैं। कभी-कभी दिल की धड़कन असामान्य हो सकती है, जो गंभीर हो सकती है। अगर आपको चक्कर आना, धड़कन तेज होना, या सांस लेने में कठिनाई हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसके साथ शराब न पिएं। अगर आपको दिल, लीवर या किडनी की बीमारी है, तो डॉक्टर को बताएं। सात दिनों से ज्यादा इसका इस्तेमाल बिना डॉक्टर की सलाह के न करें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से परामर्श करें।
💊 cetdom 10mg/325mg tablet Uses & Benefits
[{"condition":"Nausea and vomiting with pain","description":"This medicine is used to relieve nausea and vomiting while also reducing accompanying mild to moderate pain or fever.","evidence":"Well-established"},{"condition":"Gastroparesis with discomfort","description":"Domperidone improves gastric emptying, and Paracetamol helps with abdominal discomfort associated with delayed stomach emptying.","evidence":"Moderate"},{"condition":"Migraine-associated nausea and pain","description":"This combination can help manage nausea and pain during migraine attacks, though it is not a primary migraine treatment.","evidence":"Limited"},{"condition":"Post-operative nausea and pain","description":"Sometimes used after surgery to control nausea and mild pain, but only under medical supervision.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Functional dyspepsia","description":"Domperidone may be used off-label to relieve symptoms of functional dyspepsia, and Paracetamol addresses associated pain.","evidence":"Limited"},{"condition":"Nausea in early pregnancy","description":"In some cases, Domperidone may be prescribed off-label for pregnancy-related nausea, but only after careful evaluation by a doctor.","evidence":"Limited"}]
Primary treatment for: Nausea and vomiting with mild to moderate pain or fever
Also treats: Gastroparesis, Functional dyspepsia, Migraine-associated nausea
📋 Drug Information
| Generic Name(s) | Domperidone + Paracetamol |
| Brand Name | Anadom 10mg/500mg Tablet |
| Manufacturer | Biophar Lifesciences Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | Antiemetic + Analgesic/Antipyretic |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from moisture and direct sunlight. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with distinct mechanisms. Domperidone is a peripheral dopamine D2 receptor antagonist that blocks dopamine receptors in the chemoreceptor trigger zone and the gastrointestinal tract, thereby reducing nausea and vomiting and enhancing gastric motility. Paracetamol acts primarily in the central nervous system by inhibiting prostaglandin synthesis, which reduces pain and fever. Together, they provide symptomatic relief of nausea, vomiting, and mild to moderate pain or fever.
Mechanism Steps
💡 How to Take cetdom 10mg/325mg tablet
Strength: Each tablet contains Domperidone 10 mg and Paracetamol 325 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally up to three times a day, preferably before meals. However, the exact dose and frequency must be individualized by a qualified clinician based on the indication, age, weight, renal and hepatic function, and clinical response. Do not exceed the maximum recommended daily dose. This medicine is for short-term use only, and prolonged use should be avoided unless advised by a doctor. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially cardiac effects and drowsiness. Dose adjustment may be necessary based on renal and hepatic function. Use with caution and under medical supervision. |
| Renal Impairment | In patients with severe renal impairment, the dose of this medicine may need to be reduced or the dosing interval increased. Consult a doctor for individualized dosing. |
| Hepatic Impairment | In patients with hepatic impairment, the dose of this medicine should be reduced or avoided, especially due to the risk of Paracetamol-induced liver toxicity. Consult a doctor for individualized dosing. |
| Maximum Daily Dose | The maximum daily dose of this medicine should not exceed 3 tablets in 24 hours, unless otherwise prescribed by a doctor. The maximum daily dose of Paracetamol should not exceed 3000 mg from all sources. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of cetdom 10mg/325mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Major | |
| Erythromycin | Major | |
| Warfarin | Moderate | |
| Anticholinergics | Moderate | |
| Opioids | Moderate | |
| Carbamazepine | Moderate | |
| Antacids | Minor | |
| Cholestyramine | Minor | |
| Ritonavir | Major | |
| Amiodarone | Major |
🚨 Major Interactions
- Ketoconazole
- Erythromycin
- Warfarin
⚡ Moderate Interactions
- Anticholinergic drugs
- Opioid analgesics
- Carbamazepine
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. It increases the risk of liver damage from Paracetamol and can worsen drowsiness and dizziness caused by Domperidone. Chronic alcohol use also raises the risk of Paracetamol-induced hepatotoxicity.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to Domperidone or Paracetamol","Gastrointestinal obstruction, perforation, or bleeding","Prolactin-releasing pituitary tumor (prolactinoma)","Severe hepatic impairment","Severe renal impairment","Known QT prolongation or congenital long QT syndrome","Concomitant use with QT-prolonging drugs or potent CYP3A4 inhibitors"]
⚠️ Warnings & Precautions
["Use with caution in patients with heart disease or electrolyte imbalances.","Avoid in patients with liver or kidney disease unless prescribed by a doctor.","Do not exceed the recommended dose or duration of treatment.","May cause drowsiness; avoid driving or operating machinery until you know how it affects you.","Consult a doctor if symptoms persist beyond 7 days.","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.","Keep out of reach of children."]
🤱 Lactation Safety
Domperidone passes into breast milk and may cause side effects in the infant. Paracetamol is considered safe during breastfeeding. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose of this medicine can cause severe liver damage from Paracetamol and cardiac arrhythmias from Domperidone. Seek immediate medical attention. Treatment includes activated charcoal if within 1-2 hours, N-acetylcysteine for Paracetamol toxicity, and supportive care for cardiac effects. Monitor liver function, ECG, and vital signs.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Always take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration of treatment. Avoid consuming alcohol while taking this medicine, as it can increase the risk of liver damage and drowsiness. Inform your doctor if you have a history of heart problems, liver disease, kidney disease, or electrolyte imbalances. Do not use this medicine for more than seven days without consulting a doctor. If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits with your healthcare provider before using this medicine. Keep this medicine out of the reach of children. Do not drive or operate heavy machinery if you feel drowsy or dizzy after taking this medicine. Store this medicine in its original packaging at room temperature, away from moisture and direct sunlight.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more susceptible to the cardiac side effects of Domperidone and the liver toxicity of Paracetamol. Dose adjustment may be necessary, and regular monitoring of heart and liver function is advised. Use with caution and under medical supervision.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before using this medicine. The safety of this combination during pregnancy is not well established, and alternative treatments may be recommended.
🏥 Post-Surgery Considerations
This medicine may be used after surgery to manage nausea and mild pain, but only under medical supervision. Inform your surgeon and anesthesiologist about all medicines you are taking before surgery.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure. It may interact with anesthetics or other medications used during dental work. Your dentist may advise adjusting the dose or timing.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise immediately after taking this medicine if you feel drowsy or dizzy. Light activities like walking are generally safe. Consult your doctor before starting any new exercise regimen while on this medicine.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness or dizziness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It may also cause dry mouth, which can be managed by sipping water. Inform your employer if your work requires alertness.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if your symptoms do not improve within 7 days, if you experience serious side effects, or if you develop new symptoms. Do not stop abruptly if you have been on long-term therapy without medical advice.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended without medical supervision. Prolonged use of Domperidone can increase the risk of cardiac arrhythmias and hyperprolactinemia. Long-term Paracetamol use at high doses can cause liver damage. Regular monitoring of liver and heart function may be required if extended use is necessary.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Ginger may help reduce nausea and vomiting naturally.
Evidence: ModerateAcupressure bands on the wrist may help relieve nausea.
Evidence: LimitedEating small, frequent meals and avoiding trigger foods can reduce nausea.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled for vaccination, inform your healthcare provider about all medicines you are taking.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from moisture and direct sunlight. If crossing time zones, adjust dosing times gradually as advised by your doctor. Check local customs regulations regarding prescription medicines before you travel.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts working within 30 to 60 minutes after oral administration.
A: It is best taken 15-30 minutes before meals for optimal effect, but it can be taken with food if it causes stomach upset.
A: Consult your doctor before using this medicine during pregnancy. The safety profile is not well established for the combination.
A: Take it as soon as you remember if less than half the dosing interval has passed. Otherwise, skip the missed dose and continue with your regular schedule.
🤔 Common Patient Concerns
🔄 Substitutes for cetdom 10mg/325mg tablet
View AllAlternative brands with exact same active ingredient:
-
loftidase dp 10mg/325mg tabletRidhima Biocare ₹14.06 50% CHEAPER
-
Siradom 10mg/325mg TabletSSR Biotech ₹19.69 30% CHEAPER
-
domden-p tabletBMW Pharmaco India Pvt. Ltd. ₹25.31 10% CHEAPER
-
domact-p tabletIntra Labs India Pvt Ltd ₹28.13 SAME PRICE
-
analwin d 10mg/325mg tabletWinch Biotec Pvt Ltd ₹30.00 6.6% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken for any type of pain.
Fact: This medicine is specifically for nausea and vomiting with mild to moderate pain or fever. It is not effective for all types of pain. - Myth: It is safe to take this medicine for a long time.
Fact: Prolonged use can cause serious side effects, including heart rhythm problems and liver damage. It should only be used short-term under medical supervision. - Myth: This medicine can be taken without a prescription.
Fact: This medicine is a prescription drug and should only be taken under a doctor's supervision.
🔄 Alternative Options
Generic Alternatives
- Domperidone + Paracetamol combination tablets from other manufacturers
Brand Alternatives
- Domperidone + Paracetamol tablets (various brands)