centrol 25 tablet

4.7 (12 reviews)

Sertraline (25mg)

🏭 Holy Evolution Pharma 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 21, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 21, 2026

What is centrol 25 tablet used for?

Alsert 50mg Tablet (Sertraline) is used to treat NEURO CNS. It contains Sertraline (25mg), which Selective serotonin reuptake inhibitor (SSRI); increases serotonin levels in syn. Always consult your doctor before use. Take as prescribed.

Generic Name: Sertraline
Manufacturer: Holy Evolution Pharma
Form: Allopathy
Pregnancy Category: A
Prescription Required: Yes

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 centrol 25 tablet Uses & Benefits

Major depressive disorder, obsessive-compulsive disorder, panic disorder, post-traumatic stress disorder, social anxiety disorder, premenstrual dysphoric disorder.

Off-label uses: Bulimia nervosa, binge eating disorder, generalized anxiety disorder, premature ejaculation.

📋 Drug Information

Generic Name(s)	Sertraline
Brand Name	Alsert 50mg Tablet
Manufacturer	Holy Evolution Pharma
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	NEURO CNS
Action Class	Selective Seretonin Reuptake inhibitors (SSRIs)
Route of Administration	Oral.
Storage	Store at 20-25°C (68-77°F); protect from moisture.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed orally; food increases absorption slightly.

DistributionDistributes widely; volume of distribution ~20 L/kg.

Protein Binding98% bound to plasma proteins.

MetabolismHepatic via CYP2B6, CYP2C19, CYP2D6, CYP3A4; N-demethylation to norsertraline (active).

Half-Life24-26 hours (sertraline); 62-104 hours (norsertraline).

ExcretionPrimarily renal (40-45% as metabolites); fecal (40-45%).

Bioavailability~80% (oral).

Onset of Action1-2 weeks for therapeutic effect; may take 4-6 weeks for full effect.

Peak Plasma Time4-6 hours.

Duration of Action~24 hours.

How It Works

Selective serotonin reuptake inhibitor (SSRI); increases serotonin levels in synaptic cleft.

Mechanism Steps

1Sertraline binds to serotonin transporter (SERT) on presynaptic neuron.

2Blocks reuptake of serotonin into presynaptic neuron.

3Increases serotonin concentration in synaptic cleft.

💡 How to Take centrol 25 tablet

Follow your doctor's prescription exactly.

⚠️ Side Effects of centrol 25 tablet

✅ Common Side Effects

Nausea
Diarrhea
Insomnia
Dizziness
Dry mouth
Fatigue
Somnolence
Sweating
Tremor
Sexual dysfunction

🚨 Serious Side Effects

Serotonin syndrome
Suicidal thoughts/behavior
QT prolongation
Seizures
Hyponatremia
Bleeding abnormalities

⚠️ Rare Side Effects

Hepatotoxicity
Pancreatitis
Angle-closure glaucoma
Priapism
Stevens-Johnson syndrome

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
MAOIs	Major	Serotonin syndrome risk
Pimozide	Major	QT prolongation
Warfarin	Moderate	Increased INR and bleeding risk
Cimetidine	Moderate	Increased sertraline levels
Lithium	Minor	Possible serotonin syndrome

🚨 Major Interactions

MAOIs
Pimozide
Linezolid
Methylene blue
Other serotonergic drugs (risk of serotonin syndrome)

⚡ Moderate Interactions

Cimetidine
Warfarin
NSAIDs
Aspirin
CYP2D6 substrates (e.g., flecainide, propafenone)
CYP3A4 inducers/inhibitors

ℹ️ Minor Interactions

Lithium
Tryptophan
St. John's Wort
Sumatriptan

🍽️ Food Interactions

Grapefruit juice may increase sertraline levels; avoid excessive alcohol.

🍷 Alcohol Interaction

Avoid; may increase CNS depression and risk of serotonin syndrome.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity, concurrent MAOI use, pimozide use, linezolid use, methylene blue IV.

📊 Monitoring Parameters

Suicidal ideation, serotonin syndrome symptoms, liver function, renal function, ECG if high risk.

🤱 Lactation Safety

Excreted in breast milk; caution advised; monitor infant for drowsiness, poor feeding.

💊 Overdose Management

Supportive care; activated charcoal if early; monitor for serotonin syndrome, seizures, ECG changes.

⏰ Missed Dose

Take as soon as remembered; if close to next dose, skip missed dose; do not double.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 21, 2026

🔗 View Profile

🔄 Substitutes for centrol 25 tablet

View All

Alternative brands with exact same active ingredient (Sertraline (25mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Regular Customer Jul 10, 2026

Found this to be a helpful product. Good results.

Certified Buyer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Certified Buyer Jul 10, 2026

Effective and reliable. Worked as expected.

Trusted Reviewer Jul 10, 2026

Found this to be a helpful product. Good results.

Certified Buyer Jul 10, 2026

Found this to be a helpful product. Good results.

centrol 25 tablet

What is centrol 25 tablet used for?

💊 centrol 25 tablet Uses & Benefits

📋 Drug Information

🔬 Pharmacology (PK/PD)

Pharmacokinetics

How It Works

Mechanism Steps

💡 How to Take centrol 25 tablet

⚠️ Side Effects of centrol 25 tablet

✅ Common Side Effects

🚨 Serious Side Effects

⚠️ Rare Side Effects

🔬 Drug Interactions

🚨 Major Interactions

⚡ Moderate Interactions

ℹ️ Minor Interactions

🍽️ Food Interactions

🍷 Alcohol Interaction

🛡️ Safety & Warnings

🚫 Contraindications

📊 Monitoring Parameters

🤱 Lactation Safety

💊 Overdose Management

⏰ Missed Dose

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

🔄 Substitutes for centrol 25 tablet

⭐ User Reviews

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