celovan 500mg injection

4.8 (18 reviews)

Vancomycin (500mg)

🏭 Celon Laboratories Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 23, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 23, 2026

What is celovan 500mg injection used for?

CP Van 500mg Injection (Vancomycin) is used to treat ANTI INFECTIVES. It contains Vancomycin (500mg), which Inhibits bacterial cell wall synthesis by binding to D-Ala-D-Ala terminus of pep. Always consult your doctor before use. Take as prescribed.

Generic Name: Vancomycin
Manufacturer: Celon Laboratories Ltd
Form: Allopathy
Pregnancy Category: A
Prescription Required: Yes

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 celovan 500mg injection Uses & Benefits

Serious Gram-positive infections (MRSA, endocarditis, osteomyelitis, pneumonia, septicemia); oral for C.
difficile colitis.

Off-label uses: Prophylaxis in certain surgical procedures; treatment of MRSA meningitis (intrathecal).

📋 Drug Information

Generic Name(s)	Vancomycin
Brand Name	CP Van 500mg Injection
Manufacturer	Celon Laboratories Ltd
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	ANTI INFECTIVES
Action Class	Glycopeptides
Route of Administration	Intravenous (IV) infusion; oral for C. difficile.
Storage	Store at 20-25°C; reconstituted solution stable for 24 hours at room temperature, 96 hours refrigerated.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionIntravenous administration results in complete bioavailability; oral absorption is poor.

DistributionWidely distributed in body tissues and fluids; crosses placenta; low CSF penetration unless meninges inflamed.

Protein BindingAbout 30-55% bound to plasma proteins.

MetabolismMinimal metabolism; primarily excreted unchanged.

Half-Life4-6 hours in normal renal function; prolonged in renal impairment.

Excretion>90% excreted unchanged in urine via glomerular filtration.

Bioavailability100% (IV); negligible orally.

Onset of ActionRapid (IV); within minutes.

Peak Plasma TimeImmediately after IV infusion completion.

Duration of Action6-12 hours depending on dose and renal function.

How It Works

Inhibits bacterial cell wall synthesis by binding to D-Ala-D-Ala terminus of peptidoglycan precursor, blocking polymerization and cross-linking.

Mechanism Steps

1Vancomycin binds to D-Ala-D-Ala terminus of peptidoglycan precursor (lipid II) on bacterial cell membrane

2Blocks transglycosylation and transpeptidation steps

3Prevents polymerization and cross-linking of peptidoglycan

💡 How to Take celovan 500mg injection

Follow your doctor's prescription exactly.

⚠️ Side Effects of celovan 500mg injection

✅ Common Side Effects

Red man syndrome (flushing, rash, pruritus)
Nausea
Vomiting
Diarrhea
Phlebitis at injection site

🚨 Serious Side Effects

Nephrotoxicity
Ototoxicity (hearing loss, tinnitus)
Stevens-Johnson syndrome
Anaphylaxis
Neutropenia
Thrombocytopenia

⚠️ Rare Side Effects

Linear IgA bullous dermatosis
Drug reaction with eosinophilia and systemic symptoms (DRESS)
Pseudomembranous colitis
QT prolongation

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Aminoglycosides	Major	Increased nephrotoxicity and ototoxicity risk
Amphotericin B	Major	Increased nephrotoxicity risk
Cisplatin	Major	Increased nephrotoxicity risk
Cyclosporine	Major	Increased nephrotoxicity risk
Tacrolimus	Major	Increased nephrotoxicity risk
NSAIDs	Major	Increased nephrotoxicity risk
Warfarin	Moderate	Enhanced anticoagulant effect
Succinylcholine	Moderate	Neuromuscular blockade potentiation
Piperacillin/Tazobactam	Moderate	Increased risk of acute kidney injury
Cholestyramine	Minor	Reduced oral vancomycin absorption
Colestipol	Minor	Reduced oral vancomycin absorption

🚨 Major Interactions

Aminoglycosides
Amphotericin B
Cisplatin
Cyclosporine
Tacrolimus
NSAIDs

⚡ Moderate Interactions

Warfarin
Succinylcholine
Piperacillin/Tazobactam

ℹ️ Minor Interactions

Cholestyramine
Colestipol

🍷 Alcohol Interaction

No known interaction.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to vancomycin; avoid rapid IV infusion (risk of red man syndrome).

📊 Monitoring Parameters

Renal function (serum creatinine, BUN); serum trough levels (target 10-20 mcg/mL); auditory function; infusion reactions.

🤱 Lactation Safety

Excreted in breast milk; caution advised.

💊 Overdose Management

Supportive care; hemodialysis may remove vancomycin.

⏰ Missed Dose

Administer as soon as remembered; if close to next dose, skip and resume schedule; do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 23, 2026

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🔄 Substitutes for celovan 500mg injection

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Alternative brands with exact same active ingredient (Vancomycin (500mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Happy Patient Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Certified Buyer Jul 10, 2026

Effective and reliable. Worked as expected.