Alencef AZ 200mg/500mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
If experiencing severe symptoms, call emergency services immediately.
What is cefolac-az tablet used for?
This medicine is a combination antibiotic containing Cefixime 200 mg and Azithromycin 500 mg. It is used to treat bacterial infections of the respiratory tract, urinary tract, and skin. It works by killing bacteria through two different mechanisms. Take it exactly as prescribed and complete the full course.
- Generic Name: Cefixime + Azithromycin
- Manufacturer: Macleods Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 cefolac-az tablet के बारे में (Hindi Summary)
उपयोग: यह दवा सेफिक्सिम 200 मिलीग्राम और एज़िथ्रोमाइसिन 500 मिलीग्राम का संयोजन है। इसका उपयोग बैक्टीरियल संक्रमण जैसे श्वसन तंत्र संक्रमण, मूत्र मार्ग संक्रमण, त्वचा संक्रमण और टाइफाइड बुखार के इलाज के लिए किया जाता है। यह बैक्टीरिया को मारकर काम करती है। इसे डॉक्टर के निर्देशानुसार पूरा कोर्स करें।
साइड इफेक्ट्स: आम दुष्प्रभावों में दस्त, मतली, पेट दर्द, सिरदर्द और उल्टी शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन एलर्जी, गंभीर दस्त, या यकृत की समस्या हो सकती है। किसी भी गंभीर लक्षण पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। कोर्स पूरा करें, बीच में न छोड़ें। भोजन के साथ या बिना भोजन के ले सकते हैं। एंटासिड के साथ 2 घंटे का अंतराल रखें। गुर्दे या यकृत की बीमारी हो तो डॉक्टर को बताएं। शराब से बचें।
💊 cefolac-az tablet Uses & Benefits
- [{"condition":"Community-acquired pneumonia","description":"Used to treat pneumonia caused by susceptible bacteria, especially when atypical pathogens are suspected.","evidence":"Well-established"},{"condition":"Acute exacerbation of chronic bronchitis","description":"Helps resolve bacterial exacerbations in patients with chronic obstructive pulmonary disease.","evidence":"Well-established"},{"condition":"Urinary tract infections","description":"Effective against many common urinary pathogens, including E.
- coli and Klebsiella.","evidence":"Well-established"},{"condition":"Skin and soft tissue infections","description":"Used for uncomplicated skin infections such as cellulitis and abscesses.","evidence":"Well-established"},{"condition":"Typhoid fever","description":"Cefixime component is effective against Salmonella typhi; azithromycin adds coverage.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Gonorrhea","description":"Sometimes used off-label for uncomplicated gonococcal infections, but resistance patterns vary.","evidence":"Limited"},{"condition":"Pelvic inflammatory disease","description":"May be used as part of a regimen, but not standard first-line.","evidence":"Limited"}]
Primary treatment for: Bacterial infections
Also treats: Respiratory tract infections, Urinary tract infections, Skin infections, Typhoid fever
📋 Drug Information
| Generic Name(s) | Cefixime + Azithromycin |
| Brand Name | Azicef-LB Tablet |
| Manufacturer | Macleods Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Cephalosporin antibiotic + Macrolide antibiotic |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two antibiotics with different mechanisms. Cefixime, a cephalosporin, inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins, leading to bacterial lysis. Azithromycin, a macrolide, binds to the 50S ribosomal subunit and inhibits protein synthesis, thereby stopping bacterial growth. Together, they provide broad-spectrum coverage against many gram-positive and gram-negative bacteria, as well as atypical pathogens.
Mechanism Steps
💡 How to Take cefolac-az tablet
Strength: Tablet containing Cefixime 200 mg and Azithromycin 500 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet (Cefixime 200 mg + Azithromycin 500 mg) once daily or as prescribed by your doctor. The duration of treatment depends on the type and severity of infection, typically 5 to 7 days. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may have reduced renal function; dose adjustment may be necessary. Consult your doctor. |
| Renal Impairment | In patients with creatinine clearance <20 mL/min, cefixime dose should be adjusted. Azithromycin generally does not require adjustment. Consult your doctor for individualized dosing. |
| Hepatic Impairment | No specific dose adjustment for cefixime. Azithromycin should be used with caution in patients with hepatic impairment. Consult your doctor. |
| Maximum Daily Dose | The maximum recommended daily dose is one tablet (Cefixime 200 mg + Azithromycin 500 mg). Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of cefolac-az tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Ergotamine | Major | |
| Digoxin | Major | |
| Antacids | Moderate | |
| Carbamazepine | Moderate |
🚨 Major Interactions
- Warfarin
- Ergot alkaloids (e.g., ergotamine)
- Digoxin
⚡ Moderate Interactions
- Antacids (aluminum/magnesium)
- Carbamazepine
🍷 Alcohol Interaction
Alcohol may increase the risk of stomach upset and liver effects. It is advisable to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to cephalosporins, penicillins, or macrolides","History of cholestatic jaundice with prior azithromycin use","Severe renal impairment (creatinine clearance
⚠️ Warnings & Precautions
["Use with caution in patients with renal impairment; dose adjustment may be required.","May cause Clostridioides difficile-associated diarrhea; if severe diarrhea occurs, stop and consult doctor.","May prolong QT interval; caution in patients with arrhythmias or on QT-prolonging drugs.","Avoid in patients with a history of allergy to beta-lactams.","Not effective against viral infections; do not use for common cold or flu.","Complete the full course as prescribed to prevent resistance."]
🤱 Lactation Safety
Cefixime and azithromycin are excreted in breast milk in small amounts. Consult your doctor before breastfeeding while on this medicine.
💊 Overdose Management
Overdose may cause severe nausea, vomiting, diarrhea, and abdominal pain. Seek immediate medical attention. Treatment is symptomatic and supportive. Hemodialysis does not effectively remove cefixime or azithromycin.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop the course early, even if you feel better, as this can lead to antibiotic resistance. Take the tablet with a full glass of water, with or without food. If you get stomach upset, taking it with food may help. Avoid taking antacids containing aluminum or magnesium within 2 hours of this medicine, as they can reduce its absorption. Inform your doctor if you have kidney or liver problems, or if you are taking blood thinners, digoxin, or ergot medications. Do not share this medicine with others. Store it at room temperature, away from moisture and heat. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may have reduced kidney function and are more prone to side effects. Dose adjustment may be needed. Monitor for signs of superinfection and dehydration.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before taking this medicine. Both components are generally considered safe in pregnancy but should be used only if clearly needed.
🏥 Post-Surgery Considerations
This medicine may be prescribed to prevent or treat surgical site infections. Follow your surgeon's instructions carefully. Inform your surgeon if you are taking this medicine before any surgery.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, as it may interact with other medications used during dental procedures. It may also affect the oral flora and increase risk of oral thrush.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
If you experience dizziness or fatigue, avoid strenuous exercise until you feel better. Light activity is generally safe.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue in some people. Avoid driving or operating heavy machinery if you are affected. Most people can continue their normal activities.
🛑 When to Stop This Medicine
Stop taking this medicine only after completing the full prescribed course or as directed by your doctor. Do not stop early even if you feel better, as this can lead to resistance. If you experience severe side effects, contact your doctor immediately.
📅 Long-Term Use Effects
Long-term use of antibiotics can lead to bacterial resistance and superinfections. This medicine is usually prescribed for short courses. Prolonged use should be avoided unless specifically directed by a doctor. Monitor for signs of liver or kidney problems if used for extended periods.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can help prevent antibiotic-associated diarrhea.
Evidence: Well-establishedFor viral infections, rest and fluids are the mainstay.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Antibiotics do not interact with vaccines. However, if you are scheduled for a live vaccine, inform your doctor as antibiotics may affect the immune response to certain vaccines.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, adjust dosing times gradually as advised by your doctor. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling better within 2-3 days, but you must complete the full course as prescribed.
A: Yes, you can take it with or without food. If you get stomach upset, take it with a meal.
A: Take it as soon as you remember. If it's almost time for the next dose, skip the missed dose and continue your schedule. Do not double dose.
🤔 Common Patient Concerns
🔄 Substitutes for cefolac-az tablet
View AllAlternative brands with exact same active ingredient:
-
cefivin-az 200mg/500mg tabletAsvins Lifecare ₹149.00 15.3% COSTLIER
-
zimnic az 200 mg/500 mg tabletAbbott ₹215.53 66.7% COSTLIER
-
Skifi AZ 200mg/500mg TabletSun Pharmaceutical Industries Ltd ₹219.00 69.4% COSTLIER
-
cefo az 200mg/500mg tabletMedley Pharmaceuticals ₹235.00 81.8% COSTLIER
-
zofixi-az 200mg/500mg tabletZodak Healthcare ₹235.00 81.8% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Antibiotics can cure viral infections like the flu.
Fact: This medicine is effective only against bacterial infections. It does not treat viral infections. - Myth: You can stop taking antibiotics once you feel better.
Fact: You must complete the full prescribed course to prevent bacterial resistance and relapse.
🔄 Alternative Options
Generic Alternatives
- Cefixime 200 mg + Azithromycin 500 mg tablet (generic)
Brand Alternatives
- Alencef AZ 200mg/500mg tablet