ceflox-dee optic eye/ear drops - Ciprofloxacin (0.3% w/v) + Dexamethasone (0.05% w/v) medicine

ceflox-dee optic eye/ear drops - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Laborate Pharmaceuticals India Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 29, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 29, 2026

What is ceflox-dee optic eye/ear drops used for?

Alciflox D Eye/Ear Drops (Ciprofloxacin + Dexamethasone) is used to treat OPHTHAL OTOLOGICALS. It contains Ciprofloxacin (0.3% w/v) + Dexamethasone (0.05% w/v), which Ciprofloxacin inhibits bacterial DNA gyrase and topoisomerase IV; Dexamethasone . Always consult your doctor before use. Take as prescribed.

  • Generic Name: Ciprofloxacin + Dexamethasone
  • Manufacturer: Laborate Pharmaceuticals India Ltd
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š ceflox-dee optic eye/ear drops Uses & Benefits

Bacterial infections of the eye (conjunctivitis, keratitis) and ear (otitis externa, otitis media with perforated tympanic membrane) with associated inflammation

Off-label uses: Prophylaxis after ocular surgery; treatment of blepharitis

๐Ÿ“‹ Drug Information

Generic Name(s)Ciprofloxacin + Dexamethasone
Brand NameAlciflox D Eye/Ear Drops
ManufacturerLaborate Pharmaceuticals India Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassOPHTHAL OTOLOGICALS
Action ClassAntibiotic + Corticosteroid
Route of AdministrationOphthalmic and otic topical
StorageStore at 15-30ยฐC; protect from light; keep tightly closed
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionMinimal systemic absorption after ophthalmic/otic administration
DistributionLocal distribution in eye/ear tissues
Protein BindingCiprofloxacin: 20-40%; Dexamethasone: 77%
MetabolismCiprofloxacin: Hepatic (partial); Dexamethasone: Hepatic
Half-LifeCiprofloxacin: 4 hours; Dexamethasone: 3-4 hours
ExcretionCiprofloxacin: Renal (50-70% unchanged); Dexamethasone: Renal
BioavailabilityLow systemic bioavailability due to topical administration
Onset of ActionRapid (within hours)
Peak Plasma TimeNot applicable (topical)
Duration of ActionSeveral hours

How It Works

Ciprofloxacin inhibits bacterial DNA gyrase and topoisomerase IV; Dexamethasone suppresses inflammation by inhibiting phospholipase A2 and reducing prostaglandin synthesis

Mechanism Steps

1Ciprofloxacin enters bacterial cells and binds to DNA gyrase and topoisomerase IV, inhibiting DNA replication and transcription.
2Dexamethasone binds to glucocorticoid receptors, leading to inhibition of phospholipase A2 and reduced arachidonic acid release.
3Decreased prostaglandin and leukotriene synthesis results in anti-inflammatory and immunosuppressive effects.

๐Ÿ’ก How to Take ceflox-dee optic eye/ear drops

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of ceflox-dee optic eye/ear drops

โœ… Common Side Effects

  • Eye irritation
  • Stinging
  • Blurred vision
  • Taste perversion (ear drops)

๐Ÿšจ Serious Side Effects

  • Corneal perforation
  • Increased intraocular pressure
  • Cataract formation
  • Secondary infection

โš ๏ธ Rare Side Effects

  • Allergic reactions
  • Anaphylaxis
  • Tendon rupture (systemic)

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
NSAIDs Major Increased risk of tendon rupture
Antidiabetic agents Major Enhanced hypoglycemic effect
Corticosteroids Major Additive immunosuppression
Cyclosporine Moderate Increased nephrotoxicity risk
Methotrexate Moderate Increased methotrexate toxicity
Phenytoin Moderate Altered phenytoin levels
Antacids Minor Reduced ciprofloxacin absorption (if oral)
Iron supplements Minor Reduced ciprofloxacin absorption (if oral)
Zinc supplements Minor Reduced ciprofloxacin absorption (if oral)

๐Ÿšจ Major Interactions

  • Warfarin
  • NSAIDs
  • Antidiabetic agents
  • Corticosteroids

โšก Moderate Interactions

  • Cyclosporine
  • Methotrexate
  • Phenytoin

โ„น๏ธ Minor Interactions

  • Antacids
  • Iron supplements
  • Zinc supplements

๐Ÿฝ๏ธ Food Interactions

No significant food interactions (topical)

๐Ÿท Alcohol Interaction

No known interaction

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to ciprofloxacin, dexamethasone, or any component; viral infections of the eye/ear (e.g., herpes simplex); fungal infections; untreated parasitic infections; corneal perforation

๐Ÿ“Š Monitoring Parameters

Clinical improvement; signs of superinfection; intraocular pressure (if prolonged use); corneal integrity

๐Ÿคฑ Lactation Safety

Use with caution; limited data

๐Ÿ’Š Overdose Management

Topical overdose unlikely; if ingested, symptomatic treatment

โฐ Missed Dose

Apply as soon as remembered; if near next dose, skip missed dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 29, 2026

๐Ÿ”— View Profile

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