Cefleo-lb Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Tendon pain or swelling
- Numbness or tingling in hands or feet
- Seizures
If experiencing severe symptoms, call emergency services immediately.
What is cefleo-lb tablet used for?
This medicine is a combination antibiotic containing cefixime and ofloxacin, used to treat various bacterial infections. It works by killing bacteria through two different mechanisms. It is available as an immediate-release tablet and is taken orally, usually every 12 hours. It should only be used when prescribed by a doctor.
- Generic Name: Cefixime + Ofloxacin
- Manufacturer: Leo Star Healthcare Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 cefleo-lb tablet के बारे में (Hindi Summary)
उपयोग: यह दवा सेफिक्सिम और ऑफ्लोक्सासिन का संयोजन है, जिसका उपयोग विभिन्न जीवाणु संक्रमणों के इलाज के लिए किया जाता है। यह मूत्र मार्ग, श्वसन मार्ग, त्वचा और कोमल ऊतकों के संक्रमण में प्रभावी है। यह केवल डॉक्टर के पर्चे पर ही ली जानी चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, दस्त, पेट दर्द, सिरदर्द, चक्कर आना और त्वचा पर दाने शामिल हैं। गंभीर दुष्प्रभावों में गंभीर दस्त, एलर्जी, टेंडन टूटना, तंत्रिका समस्याएं और दौरे पड़ सकते हैं। कोई भी असामान्य लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी सभी एलर्जी, अन्य दवाओं और स्वास्थ्य स्थितियों के बारे में बताएं। गर्भावस्था और स्तनपान के दौरान इसका उपयोग न करें। शराब का सेवन न करें। दवा लेते समय वाहन चलाने से बचें। एंटासिड, आयरन या जिंक सप्लीमेंट के साथ इस दवा को न लें। पूरा कोर्स पूरा करें।
💊 cefleo-lb tablet Uses & Benefits
[{"condition":"Urinary tract infections","description":"Used to treat complicated and uncomplicated urinary tract infections caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Respiratory tract infections","description":"Effective against bacterial bronchitis, pneumonia, and sinusitis when caused by susceptible organisms.","evidence":"Well-established"},{"condition":"Skin and soft tissue infections","description":"Used for cellulitis, abscesses, and wound infections caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Sexually transmitted infections","description":"May be used for gonorrhea and chlamydia, but only when prescribed by a specialist.","evidence":"Established"},{"condition":"Typhoid fever","description":"Sometimes used in areas where resistance patterns allow, but not first-line in many regions.","evidence":"Limited"}]
Off-label uses: [{"condition":"Prostatitis","description":"Occasionally used for chronic bacterial prostatitis, but fluoroquinolones are preferred.","evidence":"Limited"},{"condition":"Epididymitis","description":"May be used in some cases, but specialist guidance is required.","evidence":"Limited"}]
Primary treatment for: Bacterial infections
Also treats: Urinary tract infections, Respiratory tract infections, Skin infections, Soft tissue infections
📋 Drug Information
| Generic Name(s) | Cefixime + Ofloxacin |
| Brand Name | Abixim O Tablet |
| Manufacturer | Leo Star Healthcare Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Antibiotic (Cephalosporin + Fluoroquinolone) |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C. Protect from light and moisture. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two antibiotics with distinct mechanisms. Cefixime, a third-generation cephalosporin, inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins, leading to weakened cell walls and bacterial lysis. Ofloxacin, a fluoroquinolone, inhibits DNA gyrase and topoisomerase IV, enzymes necessary for bacterial DNA replication, transcription, repair, and recombination. This dual action targets bacteria at different stages, potentially enhancing the overall antibacterial effect and reducing the likelihood of resistance development.
Mechanism Steps
💡 How to Take cefleo-lb tablet
Strength: Cefixime 200 mg + Ofloxacin 500 mg immediate-release tablet.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally every 12 hours, or as prescribed by your doctor. The exact dose and duration depend on the type and severity of the infection, your kidney and liver function, and other medications you are taking. Do not self-adjust the dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may require dose adjustment based on renal function. Use with caution due to increased risk of tendon rupture, CNS effects, and interactions with other medications. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Dose adjustment is required in patients with renal impairment. For creatinine clearance less than 30 mL/min, the dose may need to be reduced or the dosing interval extended. Consult your doctor for specific recommendations. |
| Hepatic Impairment | No specific dose adjustment is established for hepatic impairment, but use with caution and monitor liver function. |
| Maximum Daily Dose | The maximum recommended daily dose is one tablet every 12 hours, but this may vary based on the indication and patient factors. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of cefleo-lb tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Antacids | Major | |
| Warfarin | Major | |
| NSAIDs | Major | |
| Theophylline | Major | |
| Corticosteroids | Major | |
| Probenecid | Moderate | |
| Oral contraceptives | Moderate | |
| Cyclosporine | Moderate | |
| Glimepiride | Moderate | |
| Caffeine | Minor |
🚨 Major Interactions
- Antacids, sucralfate, iron, zinc
- Warfarin
- NSAIDs
- Theophylline
- Corticosteroids
⚡ Moderate Interactions
- Probenecid
- Oral contraceptives
- Cyclosporine
- Glimepiride
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol can increase the risk of dizziness, drowsiness, and stomach upset. It may also worsen liver-related side effects.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to cephalosporins, penicillins, or fluoroquinolones","History of tendon disorders with fluoroquinolones","Myasthenia gravis","Pregnancy and breastfeeding","Children under 18 years (unless specifically prescribed)","Severe renal impairment (dose adjustment required)","Epilepsy or seizure disorders"]
⚠️ Warnings & Precautions
["May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Avoid alcohol during treatment.","May cause photosensitivity; avoid excessive sun exposure.","Do not take with antacids, iron, or zinc supplements within 2 hours.","Complete the full course as prescribed.","Report any signs of allergic reaction immediately.","Use with caution in elderly patients due to increased risk of tendon rupture and CNS effects.","May affect blood sugar levels; monitor if diabetic.","Do not use for viral infections.","May reduce the efficacy of oral contraceptives; use backup contraception."]
🤱 Lactation Safety
This medicine is not recommended during breastfeeding as both cefixime and ofloxacin are excreted in breast milk and may cause serious adverse effects in the nursing infant. Consult your doctor for alternative treatments.
💊 Overdose Management
Overdose may cause nausea, vomiting, dizziness, and seizures. Seek immediate medical attention. Treatment is supportive and symptomatic. Hemodialysis may be considered for ofloxacin overdose but is not effective for cefixime.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Before taking this medicine, inform your doctor if you are allergic to any antibiotics, especially penicillins or cephalosporins, or if you have kidney or liver disease, epilepsy, myasthenia gravis, or diabetes. This medicine can make you dizzy or affect your concentration, so avoid driving or operating heavy machinery until you know how it affects you. Avoid alcohol while taking this medicine as it may increase the risk of stomach upset and dizziness. Take the tablet with plenty of water and maintain good hydration. Do not take antacids, iron supplements, or multivitamins containing zinc within 2 hours of this medicine, as they can reduce its absorption. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Do not share this medicine with others, even if they have similar symptoms. Complete the full course as prescribed, and do not skip doses. If you experience any severe side effects like difficulty breathing, swelling of the face or throat, severe diarrhea, or tendon pain, seek immediate medical attention.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of tendon rupture, CNS effects, and renal impairment. Dose adjustment may be necessary based on kidney function. Use with caution and monitor closely.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. It is not recommended during pregnancy. Discuss alternative treatments.
🏥 Post-Surgery Considerations
If you are scheduled for surgery, inform your surgeon that you are taking this medicine. It may interact with anesthetics and other medications used during surgery.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. It may interact with other medications or affect healing.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or heavy lifting while taking this medicine, as it may increase the risk of tendon rupture. If you experience joint or tendon pain, stop exercising and consult your doctor.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, drowsiness, or difficulty concentrating. Avoid driving or operating heavy machinery until you know how it affects you. It is advisable to inform your employer if your work involves such activities.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor, even if you feel better. Stopping early can lead to recurrence of infection and antibiotic resistance. If you experience severe side effects, contact your doctor immediately; they may advise you to stop.
📅 Long-Term Use Effects
Long-term use of this medicine can lead to antibiotic resistance, gut flora imbalance, and an increased risk of fungal infections. Rarely, it may cause persistent peripheral neuropathy, tendon damage, or liver and kidney problems. Regular monitoring may be required if used for prolonged periods. It should only be used for the prescribed duration.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Based on culture and sensitivity, a narrower-spectrum antibiotic may be used instead of this combination.
Evidence: Well-establishedCan help prevent antibiotic-associated diarrhea when taken alongside antibiotics.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Antibiotics like this medicine may reduce the efficacy of live bacterial vaccines such as the typhoid vaccine. Consult your doctor regarding vaccination timing.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from extreme heat or moisture. If crossing time zones, adjust dosing times gradually, but consult your doctor for specific advice. Check local customs regulations regarding prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling better within 24-48 hours, but it is important to complete the full course as prescribed.
A: Yes, you can take it with or without food. Taking it with food may help reduce stomach upset.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
A: This medicine is not recommended during pregnancy unless specifically prescribed by your doctor. Consult your doctor for safer alternatives.
A: It is best to avoid alcohol while taking this medicine as it can increase dizziness and stomach upset.
🤔 Common Patient Concerns
🔄 Substitutes for cefleo-lb tablet
View AllAlternative brands with exact same active ingredient:
-
makxime-oz tabletMaksal Pharmaceuticals (P) Ltd ₹111.56 47.1% CHEAPER
-
cefirex ox 200mg/500mg tabletMedrex Pharma ₹140.00 33.6% CHEAPER
-
melfix oz 200mg/500mg tabletElwiss Biotech Private Limited ₹153.75 27.1% CHEAPER
-
grewia oz 200mg/500mg tabletAdvance Revive ₹160.31 24% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure viral infections like the common cold.
Fact: This medicine is an antibiotic and is only effective against bacterial infections. It does not treat viral infections. - Myth: You can stop taking this medicine as soon as you feel better.
Fact: You must complete the full course as prescribed, even if you feel better, to prevent the infection from returning and to reduce antibiotic resistance. - Myth: This medicine is safe to take during pregnancy.
Fact: This medicine is not recommended during pregnancy unless specifically prescribed by a doctor, as it may harm the developing baby.
🔄 Alternative Options
Generic Alternatives
- Cefixime 200 mg + Ofloxacin 500 mg tablet (various manufacturers)
Brand Alternatives
- Cefleo-LB Tablet