cefkiazid tz 1000mg/125mg injection
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
What is cefkiazid tz 1000mg/125mg injection used for?
This medicine contains Ceftazidime (1000mg) + Tazobactum (125mg) and is used to treat ANTI INFECTIVES. Ceftazidime inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs);. Always consult your doctor before use.
- Generic Name: Ceftazidime + Tazobactam
- Manufacturer: Kiama Lifesciences
- Form: Allopathy
- Pregnancy Category: Category B
- Prescription Required: Yes
💊 cefkiazid tz 1000mg/125mg injection Uses & Benefits
Treatment of hospital-acquired pneumonia, complicated urinary tract infections, complicated intra-abdominal infections, and febrile neutropenia.
Off-label uses: Bone and joint infections, Cystic fibrosis exacerbations
📋 Drug Information
| Generic Name(s) | Ceftazidime + Tazobactam |
| Brand Name | Actacrez 2.25g Injection |
| Manufacturer | Kiama Lifesciences |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Antibiotic (Cephalosporin + Beta-lactamase inhibitor) |
| Route of Administration | Intravenous (IV) |
| Storage | Store at 20-25°C; protect from light; reconstituted solution stable for 24 hours at room temperature or 7 days refrigerated. |
| Shelf Life | As per manufacturer |
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Ceftazidime inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs); Tazobactam inhibits beta-lactamases, preventing ceftazidime degradation.
Mechanism Steps
💡 How to Take cefkiazid tz 1000mg/125mg injection
Follow your doctor's prescription exactly.
⚠️ Side Effects of cefkiazid tz 1000mg/125mg injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased INR and bleeding risk |
| Aminoglycosides | Major | Increased nephrotoxicity risk |
| Chloramphenicol | Major | Antagonistic effect |
| Probenecid | Moderate | Decreased renal excretion of ceftazidime |
| Loop diuretics | Moderate | Increased nephrotoxicity risk |
| Oral contraceptives | Moderate | Reduced contraceptive efficacy |
| Antacids | Minor | No significant interaction |
| Iron supplements | Minor | No significant interaction |
🚨 Major Interactions
- Warfarin
- Aminoglycosides
- Chloramphenicol
⚡ Moderate Interactions
- Probenecid
- Loop diuretics
- Oral contraceptives
🍷 Alcohol Interaction
No known interaction, but alcohol may increase side effects like dizziness.
🛡️ Safety & Warnings
🚫 Contraindications
Hypersensitivity to ceftazidime, tazobactam, or other cephalosporins; history of severe allergic reactions to penicillins.
🤱 Lactation Safety
Excreted in breast milk in low amounts; use with caution.
💊 Overdose Management
Supportive care; hemodialysis may enhance elimination.
⏰ Missed Dose
Administer as soon as remembered; do not double dose.
🔄 Substitutes for cefkiazid tz 1000mg/125mg injection
View AllAlternative brands with exact same active ingredient:
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Tazonat P 1000mg/125mg InjectionAncalima Lifesciences Ltd ₹125.00 65.3% CHEAPER
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bbcef t 1000mg/125mg injectionLifeCare Formulation Pvt Ltd ₹149.90 58.4% CHEAPER
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tazid xp 1000 mg/125 mg injectionAlkem Laboratories Ltd ₹202.58 43.7% CHEAPER
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zidime t 1000 mg/125 mg injectionAbbott ₹203.95 43.3% CHEAPER
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cetalic tz 1000mg/125mg injectionAnabolic Remedies Pvt Ltd ₹220.00 38.9% CHEAPER
Medical Note: Always consult your doctor before switching medications.