Akuzid 1000 Injection (Ceftazidime 1000 mg): Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Swelling of the face, lips, tongue, or throat, or difficulty breathing.
- Severe rash with blisters, peeling skin, or sores in the mouth or eyes.
- Watery or bloody diarrhea with fever or stomach cramps.
- Seizure, confusion, or unusual movements.
- Unusual bruising, bleeding, or paleness.
- Decreased urine output or swelling in the legs.
- Yellowing of the eyes or skin, or dark urine.
- Chest pain, fainting, or very low blood pressure.
If experiencing severe symptoms, call emergency services immediately.
What is cefziset 1000mg injection used for?
This medicine is an intravenous antibiotic containing Ceftazidime 1000 mg. It is used to treat serious bacterial infections such as hospital-acquired pneumonia, complicated urinary tract infections, bloodstream infections, and skin infections. It works by breaking down the bacterial cell wall, leading to bacterial death. It must be given by a healthcare professional and is not for viral infections.
- Generic Name: Ceftazidime
- Manufacturer: Biosync Pharmaceuticals Pvt. Ltd.
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 cefziset 1000mg injection के बारे में (Hindi Summary)
उपयोग: यह दवा सेफ्टाज़िडाइम 1000 मिलीग्राम का इंजेक्शन है, जिसे नस के माध्यम से दिया जाता है। यह गंभीर बैक्टीरियल संक्रमणों के इलाज के लिए इस्तेमाल की जाती है, जैसे अस्पताल में होने वाला निमोनिया, पेशाब की नली का जटिल संक्रमण, खून का संक्रमण, त्वचा और मांसपेशियों का संक्रमण, और पेट के अंदर के संक्रमण। यह दवा बैक्टीरिया की कोशिका भित्ति को तोड़कर उन्हें मार देती है। यह वायरल संक्रमण जैसे सर्दी-जुकाम के लिए असरदार नहीं है। यह दवा केवल डॉक्टर या नर्स द्वारा ही दी जानी चाहिए और डोज़ आपकी किडनी की स्थिति, उम्र और वजन के अनुसार तय की जाती है।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में इंजेक्शन लगाने की जगह पर दर्द, लालिमा या सूजन, दस्त, जी मिचलाना, उल्टी, पेट में असहजता, सिरदर्द, चक्कर आना और हल्के दाने शामिल हैं। कुछ मरीजों में लिवर एंजाइम अस्थायी रूप से बढ़ सकते हैं। गंभीर दुष्प्रभाव कम होते हैं, लेकिन एलर्जी, सांस लेने में कठिनाई, चेहरे या गले में सूजन, गंभीर त्वचा प्रतिक्रियाएं, खूनी दस्त, दौरे पड़ना, और खून की कोशिकाओं में कमी हो सकती है। अगर आपको कोई नई समस्या हो तो तुरंत डॉक्टर को बताएं।
सुरक्षा सलाह: यह दवा केवल अस्पताल या डॉक्टर की देखरेख में ही दी जानी चाहिए, इसे घर पर खुद से न लगवाएं। इंजेक्शन से पहले अपनी सभी एलर्जी, खासकर पेनिसिलिन या सेफलोस्पोरिन से एलर्जी के बारे में डॉक्टर को जरूर बताएं। अगर आपको किडनी या लिवर की बीमारी है, दौरे पड़ते हैं, या आप गर्भवती हैं या स्तनपान करा रही हैं, तो डॉक्टर को बताएं। इलाज के दौरान पर्याप्त पानी पिएं, जब तक डॉक्टर ने पानी कम करने की सलाह न दी हो। बेहतर महसूस होने पर भी कोर्स पूरा करें। शराब न पिएं। अगर दाने, सूजन, सांस लेने में तकलीफ, गंभीर दस्त या असामान्य रक्तस्राव हो तो तुरंत डॉक्टर से मिलें।
💊 cefziset 1000mg injection Uses & Benefits
[{"condition":"Hospital-acquired pneumonia","description":"Used to treat serious lung infections acquired during hospital stay, including those caused by Pseudomonas aeruginosa and other susceptible gram-negative bacteria.","evidence":"Well-established"},{"condition":"Complicated urinary tract infections","description":"Effective for kidney and bladder infections that are complicated or caused by resistant organisms, especially when intravenous therapy is needed.","evidence":"Well-established"},{"condition":"Bloodstream infections (septicemia)","description":"Given intravenously to treat bacteria in the bloodstream, often as part of a combination regimen in critically ill patients.","evidence":"Well-established"},{"condition":"Skin and soft tissue infections","description":"Used for severe cellulitis, abscesses, and wound infections caused by susceptible bacteria when oral therapy is not suitable.","evidence":"Well-established"},{"condition":"Intra-abdominal infections","description":"Prescribed for complicated abdominal infections such as peritonitis and intra-abdominal abscess, usually along with other antibiotics to cover anaerobes.","evidence":"Well-established"},{"condition":"Febrile neutropenia","description":"Used as empirical therapy in cancer patients with fever and low white blood cell counts, often combined with an aminoglycoside or another agent.","evidence":"Well-established"},{"condition":"Bone and joint infections","description":"May be used for osteomyelitis and septic arthritis caused by susceptible organisms, often followed by oral therapy after clinical improvement.","evidence":"Moderate"},{"condition":"Meningitis","description":"Used in some cases of bacterial meningitis caused by susceptible gram-negative bacteria, usually in combination with other antibiotics.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Melioidosis","description":"Sometimes used as part of initial intensive therapy for Burkholderia pseudomallei infection in regions where the disease is endemic.","evidence":"Limited"},{"condition":"Nocardiosis","description":"Occasionally used in combination regimens for Nocardia infections when susceptibility testing supports its use.","evidence":"Limited"}]
Primary treatment for: Serious bacterial infections caused by susceptible organisms.
Also treats: Hospital-acquired pneumonia, Complicated urinary tract infections, Bloodstream infections, Skin and soft tissue infections, Intra-abdominal infections, Febrile neutropenia
📋 Drug Information
| Generic Name(s) | Ceftazidime |
| Brand Name | Akuzid 1000 Injection |
| Manufacturer | Biosync Pharmaceuticals Pvt. Ltd. |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Cephalosporins: 3 generation |
| Route of Administration | Intravenous (into a vein) |
| Storage | Store the unopened vial at room temperature between 15°C and 30°C, away from direct sunlight and moisture. Once reconstituted, the solution should be used within the time specified by the manufacturer or stored as directed by the pharmacist. Do not freeze the reconstituted solution unless specifically instructed. |
| Shelf Life | The shelf life of the unopened vial is typically 24 months from the date of manufacture. Once reconstituted, use within the period recommended by the manufacturer, usually within a few hours to 24 hours depending on storage conditions. |
| WHO Guideline | Not established from the available information for this specific product. Antibiotic use should follow local hospital guidelines and national stewardship programs. |
| ICMR Guideline | Not established from the available information for this specific product. Always follow institutional antibiotic policy and culture sensitivity reports. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine is a beta-lactam antibiotic that kills bacteria by interfering with the synthesis of the bacterial cell wall. Ceftazidime binds to specific penicillin-binding proteins located on the inner membrane of susceptible bacteria, which inhibits the cross-linking of peptidoglycan strands. Without proper cross-linking, the bacterial cell wall becomes weak and cannot withstand normal osmotic pressure. This leads to cell lysis and death of the bacteria. Because human cells do not have a peptidoglycan cell wall, this medicine selectively targets bacteria and has little direct effect on human cells.
Mechanism Steps
💡 How to Take cefziset 1000mg injection
Strength: Ceftazidime 1000 mg injection (intravenous).
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 1 gram given intravenously every 8 to 12 hours, but the exact dose and interval depend on the type and severity of the infection, the bacteria involved, and the patient's kidney function. For serious infections such as hospital-acquired pneumonia or bloodstream infections, higher doses or more frequent intervals may be used. In patients with kidney impairment, the dose or frequency must be reduced. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information for this specific product. Consult a pediatrician for weight-based dosing and appropriate monitoring. |
| Elderly Dosage | Older adults may need a lower dose because kidney function often declines with age. The dose should be adjusted based on measured kidney function, and kidney function should be monitored during treatment. |
| Renal Impairment | In patients with kidney impairment, the dose and dosing interval must be adjusted according to the degree of renal impairment. A common approach is to give a normal loading dose and then reduce subsequent doses or extend the interval. Dose must be individualized by a qualified clinician based on renal function. |
| Hepatic Impairment | No specific dose adjustment is usually required for liver impairment alone, because this medicine is not significantly metabolized by the liver. However, if both liver and kidney function are impaired, dose adjustment may be needed. |
| Maximum Daily Dose | The maximum daily dose is not fixed and depends on the infection and kidney function. In adults with normal kidney function, doses up to 6 grams per day have been used in severe infections under close medical supervision. Dose must be individualized by a qualified clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of cefziset 1000mg injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Gentamicin | Major | |
| Furosemide | Major | |
| Warfarin | Moderate | |
| Probenecid | Moderate | |
| Chloramphenicol | Major | |
| Oral contraceptives | Minor |
🚨 Major Interactions
- Aminoglycosides (e.g., gentamicin, tobramycin)
- Loop diuretics (e.g., furosemide)
- Chloramphenicol
⚡ Moderate Interactions
- Warfarin
- Probenecid
🍷 Alcohol Interaction
Alcohol should be avoided while receiving this medicine because it can increase the risk of dizziness, nausea, and stomach discomfort. It may also make it harder to judge your recovery from the infection.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known severe allergy to ceftazidime or any other cephalosporin antibiotic","History of anaphylaxis to penicillin or other beta-lactam antibiotics","Previous severe skin reaction such as Stevens-Johnson syndrome after a cephalosporin"]
⚠️ Warnings & Precautions
["Use with caution in patients with kidney disease because the dose may need to be reduced.","Use with caution in patients with a history of seizures, as high blood levels can increase seizure risk.","Prolonged use may lead to overgrowth of resistant bacteria or fungi.","Antibiotic-associated diarrhea can occur; report severe or bloody diarrhea immediately.","Do not mix this medicine with other drugs in the same intravenous line unless compatibility is confirmed.","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding."]
🤱 Lactation Safety
This medicine passes into breast milk in small amounts. It is usually considered compatible with breastfeeding, but the baby should be monitored for diarrhea, thrush, or rash. Consult your doctor before breastfeeding while receiving this medicine.
💊 Overdose Management
Overdose with this medicine can cause brain-related side effects such as confusion, seizures, and encephalopathy, especially in patients with kidney impairment. Treatment is supportive and may include stopping the drug, monitoring vital signs, and considering hemodialysis in severe cases because this medicine can be removed by dialysis. Contact a poison control center or emergency department immediately if overdose is suspected.
⏰ Missed Dose
Because this medicine is given by a healthcare professional, missed doses are usually managed by the clinical team. If you miss a scheduled infusion appointment, contact your doctor or clinic as soon as possible to reschedule. Do not try to catch up by taking extra doses on your own.
Additional Safety Advice
This medicine must be given only under medical supervision, so do not attempt to use it at home or adjust the dose yourself. Tell your doctor about all your allergies, especially any previous reaction to penicillin or cephalosporin antibiotics, before the first dose. Inform the healthcare team if you have kidney disease, liver disease, a seizure disorder, or if you are pregnant, planning pregnancy, or breastfeeding. While receiving this medicine, drink enough fluids unless your doctor has restricted fluids for another reason. Do not stop the course early even if you feel better, because incomplete treatment can allow the infection to return and can promote antibiotic resistance. Avoid alcohol during treatment because it may worsen stomach upset and dizziness. If you develop a rash, swelling, breathing difficulty, severe diarrhea, or unusual bleeding, seek medical help immediately. Keep all follow-up appointments so your doctor can monitor your response, kidney function, and blood counts when needed.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Older adults are more likely to have reduced kidney function, which can increase the risk of side effects such as seizures and kidney problems. The dose should be adjusted based on measured kidney function, and kidney function should be monitored during treatment. Older adults may also be more sensitive to dizziness and confusion.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, discuss this with your doctor before starting treatment. This medicine is generally considered acceptable in pregnancy when needed for a serious bacterial infection, but the decision should be made by a qualified clinician after weighing the benefits and risks.
🏥 Post-Surgery Considerations
This medicine may be used after surgery to treat or prevent serious bacterial infections. The dose and duration depend on the type of surgery and the infection risk. Follow your surgeon's instructions and complete the full course if prescribed.
🦷 Dental Procedures
If you have a dental procedure while receiving this medicine, inform your dentist about the medicine and any allergies. In some cases, your doctor may recommend delaying dental work until you have recovered from the infection. Good oral hygiene is important during treatment.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While receiving this medicine, you may feel tired or dizzy, so avoid strenuous exercise until you feel better. Light activity such as walking may be helpful if your doctor approves. If you have a serious infection, follow your doctor's advice about activity restrictions.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is given intravenously in a hospital or clinic, so you may need to take time off work or arrange your schedule around treatment appointments. You may feel tired or dizzy during treatment, so avoid driving or operating heavy machinery until you feel fully alert. Discuss your work schedule with your doctor and employer.
🛑 When to Stop This Medicine
Do not stop this medicine on your own. Your doctor will decide when to stop based on your clinical response, culture results, and overall condition. If you develop serious side effects such as a severe allergic reaction, severe diarrhea, or seizures, your doctor may stop the medicine and change the treatment plan.
📅 Long-Term Use Effects
Long-term use of this medicine is not common because it is usually given for a limited course. Prolonged use can increase the risk of antibiotic resistance, fungal superinfection, and Clostridioides difficile-associated diarrhea. Rarely, it can affect kidney function, blood counts, or liver enzymes. If long-term therapy is needed, your doctor will monitor your kidney function, blood counts, and liver function regularly.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Once you improve, your doctor may switch you to oral antibiotics to complete the course.
Evidence: Well-establishedDepending on culture results, other antibiotics such as cefepime, piperacillin-tazobactam, or meropenem may be used.
Evidence: Well-establishedRest, fluids, and fever control are important alongside antibiotics.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with most vaccines, but if you are receiving live vaccines, discuss the timing with your doctor. Antibiotics may affect the response to some live bacterial vaccines such as typhoid vaccine. Follow your doctor's advice about vaccination during and after treatment.
📦 Storage Guide
✅ DO
Store the unopened vial at room temperature between 15°C and 30°C.
❌ DON'T
Do not freeze the unopened vial.
✅ DO
Keep the vial in its original carton to protect it from light.
❌ DON'T
Do not store in direct sunlight or in a hot place.
✅ DO
Use the reconstituted solution within the time recommended by the manufacturer.
❌ DON'T
Do not use the solution if it is cloudy or contains particles.
✅ DO
Keep out of reach of children.
❌ DON'T
Do not transfer the medicine to unmarked containers.
✈️ Traveling with This Medicine
This medicine is given intravenously in a hospital or clinic, so travel planning should be discussed with your doctor. If you need to continue treatment while traveling, carry a copy of your prescription and a letter from your doctor explaining the medicine and its indication. Keep the vials in their original packaging and store them at room temperature, away from direct sunlight. If you are flying, carry the medicine in your hand luggage with proper documentation. Check the laws of your destination country regarding injectable antibiotics, and arrange for a healthcare professional to administer the doses. Do not attempt to self-administer this medicine during travel.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start to feel better within 24 to 72 hours after starting treatment, but the full effect depends on the type and severity of the infection. Always complete the full course as prescribed.
A: This medicine is given intravenously and must be administered by a healthcare professional, usually in a hospital or clinic. In some cases, home infusion services may be arranged, but only under medical supervision.
A: Contact your doctor or clinic as soon as possible to reschedule. Do not try to catch up by taking extra doses on your own.
A: It can be used in kidney disease, but the dose and dosing interval must be adjusted based on your kidney function. Your doctor will monitor your kidney function during treatment.
A: It is best to avoid alcohol during treatment because it can worsen dizziness, nausea, and stomach upset.
🤔 Common Patient Concerns
🔄 Substitutes for cefziset 1000mg injection
View AllAlternative brands with exact same active ingredient:
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hanuzid 1000mg injectionHanuchem Laboratories ₹23.44 62.6% CHEAPER
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gracef 1000mg injectionGRAF Laboratories Pvt Ltd ₹54.02 13.7% CHEAPER
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ceftabit 1000mg injectionCubit Healthcare ₹115.00 83.7% COSTLIER
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cefatus 1000mg injectionTusker Pharma Pvt Ltd ₹115.63 84.7% COSTLIER
-
jotadine 1000mg injectionMultilax Pharmaceuticals Pvt Ltd ₹135.94 117.2% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure any infection.
Fact: This medicine only works against certain susceptible bacteria and is not effective against viruses or fungi. - Myth: You can stop the antibiotic once you feel better.
Fact: Stopping early can allow the infection to return and can promote antibiotic resistance. Complete the full course as prescribed. - Myth: This medicine is safe for everyone.
Fact: People with severe penicillin or cephalosporin allergy should not receive this medicine. - Myth: This medicine can be taken as a pill instead.
Fact: This product is an intravenous injection and must be given by a healthcare professional.
🔄 Alternative Options
Generic Alternatives
- Ceftazidime 1000 mg injection
Brand Alternatives
- Akuzid 1000 injection