bbcef s 1000mg/500mg injection
What is bbcef s 1000mg/500mg injection used for?
bbcef s 1000mg/500mg injection (Ceftazidime + Sulbactam) is used to treat ANTI INFECTIVES. It contains Ceftazidime (1000mg) + Sulbactam (500mg), which Ceftazidime inhibits bacterial cell wall synthesis by binding to penicillin-bind. Always consult your doctor before use. Take as prescribed.
- Generic Name: Ceftazidime + Sulbactam
- Manufacturer: LifeCare Formulation Pvt Ltd
- Form: Allopathy
- Pregnancy Category: B
- Prescription Required: Yes
๐ bbcef s 1000mg/500mg injection Uses & Benefits
Treatment of infections caused by susceptible bacteria: lower respiratory tract, urinary tract, skin and soft tissue, intra-abdominal, septicemia, and febrile neutropenia.
Off-label uses: Meningitis (if susceptible), Bone and joint infections
๐ Drug Information
| Generic Name(s) | Ceftazidime + Sulbactam |
| Brand Name | bbcef s 1000mg/500mg injection |
| Manufacturer | LifeCare Formulation Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Cephalosporin + Beta-lactamase inhibitor |
| Route of Administration | Intravenous (IV) injection or infusion |
| Storage | Store at 20-25ยฐC; protect from light. Reconstituted solution stable for 24 hours at room temperature or 7 days refrigerated. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Ceftazidime inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs). Sulbactam inhibits beta-lactamases, preventing degradation of ceftazidime.
Mechanism Steps
๐ก How to Take bbcef s 1000mg/500mg injection
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of bbcef s 1000mg/500mg injection
โ Common Side Effects
- Diarrhea
- Nausea
- Vomiting
- Rash
- Injection site reactions
๐จ Serious Side Effects
- Severe allergic reactions (anaphylaxis)
- Clostridioides difficile-associated diarrhea
- Seizures
- Nephrotoxicity
- Hepatotoxicity
โ ๏ธ Rare Side Effects
- Hemolytic anemia
- Agranulocytosis
- Stevens-Johnson syndrome
- Toxic epidermal necrolysis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Aminoglycosides | Major | Increased nephrotoxicity risk |
| Loop diuretics | Major | Increased nephrotoxicity risk |
| Probenecid | Moderate | Decreased renal excretion of ceftazidime |
| Oral contraceptives | Moderate | Reduced contraceptive efficacy |
| Antacids | Minor | Decreased absorption (not relevant for IV) |
| Iron supplements | Minor | Decreased absorption (not relevant for IV) |
๐จ Major Interactions
- Warfarin
- Aminoglycosides
- Loop diuretics
โก Moderate Interactions
- Probenecid
- Oral contraceptives
โน๏ธ Minor Interactions
- Antacids
- Iron supplements
๐ฝ๏ธ Food Interactions
No significant food interactions.
๐ท Alcohol Interaction
May cause disulfiram-like reaction (rare). Avoid alcohol.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to ceftazidime, sulbactam, or other cephalosporins; history of severe allergic reactions to penicillins.
๐ Monitoring Parameters
Renal function, hepatic function, CBC, signs of superinfection, bleeding, and allergic reactions.
๐คฑ Lactation Safety
Excreted in breast milk in low amounts; use with caution.
๐ Overdose Management
Supportive care; hemodialysis may enhance elimination.
โฐ Missed Dose
Administer as soon as remembered; if near next dose, skip missed dose. Do not double dose.