cedopil 100mg/5ml dry syrup - Cefpodoxime Proxetil (100mg/5ml) medicine

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🏭 Psychotropics India Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 17, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Oct 17, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe or persistent diarrhea, which may indicate Clostridium difficile infection.
  • Rash, itching, or swelling of the face, lips, or throat, which may signal a severe allergic reaction.
  • Difficulty breathing or wheezing.
  • Yellowing of the skin or eyes (jaundice).
  • Unusual bleeding or bruising.
  • Decreased urine output or swelling in the legs.
  • High fever that does not improve after 48-72 hours of treatment.

If experiencing severe symptoms, call emergency services immediately.

What is cedopil 100mg/5ml dry syrup used for?

This medicine is an antibiotic syrup containing cefpodoxime proxetil, used to treat bacterial infections such as respiratory tract infections, ear infections, and urinary tract infections. It works by killing bacteria. Take it with food and complete the full course as prescribed.

  • Generic Name: Cefpodoxime Proxetil
  • Manufacturer: Psychotropics India Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 cedopil 100mg/5ml dry syrup के बारे में (Hindi Summary)

उपयोग: यह दवा एक एंटीबायोटिक सिरप है जिसमें सेफपोडॉक्सिम प्रोक्सेटिल नामक सक्रिय तत्व होता है। यह तीसरी पीढ़ी के सेफलोस्पोरिन वर्ग की दवा है और बैक्टीरिया के कारण होने वाले संक्रमणों के इलाज के लिए उपयोग की जाती है। यह श्वसन तंत्र के संक्रमण, कान के संक्रमण, गले के संक्रमण, मूत्र मार्ग के संक्रमण और त्वचा के संक्रमण के इलाज में प्रभावी है। यह दवा बैक्टीरिया की कोशिका भित्ति को नष्ट करके उन्हें मार देती है। इसे भोजन के साथ लेना चाहिए और डॉक्टर द्वारा बताई गई पूरी अवधि तक लेना चाहिए, भले ही लक्षण ठीक हो जाएं।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में दस्त, जी मिचलाना, पेट दर्द और सिरदर्द शामिल हैं। ये आमतौर पर हल्के और अस्थायी होते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन इनमें गंभीर एलर्जी प्रतिक्रिया, क्लोस्ट्रीडियम डिफिसाइल से जुड़े दस्त, और रक्त विकार शामिल हो सकते हैं। यदि आपको लगातार दस्त, दाने, या कोई असामान्य लक्षण महसूस हो तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। खुराक न छोड़ें और न ही समय से पहले बंद करें। उपयोग से पहले बोतल को अच्छी तरह हिलाएं। सही खुराक मापने के लिए मापने वाला कप या सिरिंज का उपयोग करें। यदि आपको गुर्दे की समस्या, एंटीबायोटिक से एलर्जी, या पेट की बीमारी है तो डॉक्टर को बताएं। एंटासिड या आयरन सप्लीमेंट इस दवा से 2 घंटे पहले या बाद में लें। यदि आप गर्भवती या स्तनपान करा रही हैं, तो डॉक्टर से सलाह लें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 cedopil 100mg/5ml dry syrup Uses & Benefits

[{"condition":"Community-acquired pneumonia","description":"This medicine is effective against common respiratory pathogens such as Streptococcus pneumoniae and Haemophilus influenzae, helping to resolve infection and improve symptoms.","evidence":"Well-established"},{"condition":"Acute bacterial exacerbation of chronic bronchitis","description":"It reduces bacterial load in the airways, alleviating cough, sputum production, and shortness of breath.","evidence":"Well-established"},{"condition":"Acute otitis media","description":"This medicine is used to treat middle ear infections in children and adults, caused by bacteria like Streptococcus pneumoniae and Haemophilus influenzae.","evidence":"Well-established"},{"condition":"Pharyngitis and tonsillitis","description":"It is effective against Streptococcus pyogenes, helping to relieve sore throat and prevent complications such as rheumatic fever.","evidence":"Well-established"},{"condition":"Uncomplicated urinary tract infections","description":"This medicine is active against common uropathogens such as Escherichia coli and Klebsiella pneumoniae, reducing urinary symptoms.","evidence":"Well-established"},{"condition":"Skin and soft tissue infections","description":"It is used for infections like cellulitis and abscesses caused by susceptible bacteria, including Staphylococcus aureus and Streptococcus species.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Lyme disease","description":"Sometimes used as an alternative to doxycycline in patients who cannot take tetracyclines, but evidence is limited.","evidence":"Limited"},{"condition":"Gonorrhea","description":"May be used as an alternative treatment for uncomplicated gonorrhea, but not first-line due to resistance concerns.","evidence":"Limited"}]

Primary treatment for: Bacterial infections

Also treats: Respiratory tract infections, Otitis media, Urinary tract infections, Skin infections

📋 Drug Information

Generic Name(s)Cefpodoxime Proxetil
Brand NameAxone O 200mg Tablet
ManufacturerPsychotropics India Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassCephalosporins: 3 generation
Route of AdministrationOral
StorageStore the dry powder at room temperature (15-30°C) in a dry place, away from direct sunlight. After reconstitution, store the suspension in the refrigerator (2-8°C) and discard any unused portion after 14 days. Do not freeze.
Shelf LifeThe dry powder has a shelf life of 24 months from the date of manufacture. After reconstitution, the suspension is stable for 14 days when stored in the refrigerator.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always prescribe this medicine with food to enhance absorption and minimize gastrointestinal upset.
2
Instruct patients to complete the full course even if symptoms improve to prevent resistance.
3
Advise patients to shake the suspension well before each dose to ensure uniform drug distribution.
4
Warn patients about potential interaction with antacids and iron supplements; separate administration by at least 2 hours.
5
Monitor renal function in elderly patients and those with kidney disease; adjust dose accordingly.
6
Educate patients on recognizing signs of severe allergic reactions and when to seek immediate help.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Ear pain
This medicine is commonly prescribed for ear infections.
Likely Use
✅
Cough with fever
May be used for respiratory tract infections.
Likely Use
✅
Burning urination
Used for urinary tract infections.
Likely Use
❌
Runny nose
This medicine is not effective for viral colds.
Not Primary
❌
Headache alone
Not a primary treatment for headache.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionCefpodoxime proxetil is absorbed from the gastrointestinal tract after oral administration. The prodrug is hydrolyzed to the active cefpodoxime. Food increases the absorption; therefore, it is recommended to take with food. Bioavailability is approximately 50% when taken with food.
DistributionCefpodoxime distributes into various body tissues and fluids, including lung tissue, tonsils, sinus fluid, and urine. It does not penetrate the cerebrospinal fluid well in the absence of inflammation. Protein binding is approximately 21-29%.
Protein BindingApproximately 21-29% bound to plasma proteins.
MetabolismCefpodoxime proxetil is a prodrug that is hydrolyzed in the gastrointestinal tract to cefpodoxime, the active antibiotic. Cefpodoxime itself is not significantly metabolized.
Half-LifeThe elimination half-life of cefpodoxime is approximately 2 to 3 hours in adults with normal renal function.
ExcretionCefpodoxime is primarily excreted unchanged in the urine. About 80% of the administered dose is recovered in urine within 24 hours.
BioavailabilityApproximately 50% when taken with food.
Onset of ActionThe onset of action is typically within 1 to 2 hours after oral administration, but clinical improvement may take 24 to 48 hours.
Peak Plasma TimePeak plasma concentrations are achieved approximately 2 to 3 hours after oral administration with food.
Duration of ActionThe duration of action is approximately 8 to 12 hours, which supports twice-daily dosing.

How It Works

This medicine works by binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall. This binding inhibits the final transpeptidation step of peptidoglycan synthesis, which is essential for bacterial cell wall integrity. As a result, the bacterial cell wall becomes weakened, leading to cell lysis and death. This medicine is bactericidal, meaning it kills the bacteria directly. It is effective against a wide range of gram-positive and gram-negative bacteria, but it is not active against methicillin-resistant Staphylococcus aureus (MRSA) or Pseudomonas aeruginosa.

Mechanism Steps

1
Binding to penicillin-binding proteins: This medicine binds to specific PBPs on the bacterial cell membrane, which are enzymes involved in cell wall synthesis.
2
Inhibition of peptidoglycan cross-linking: By binding to PBPs, it prevents the cross-linking of peptidoglycan chains, which are essential for the strength and rigidity of the bacterial cell wall.
3
Activation of autolysins: The inhibition of cell wall synthesis leads to the activation of bacterial autolytic enzymes that degrade the existing cell wall.
4
Bacterial cell lysis and death: The weakened cell wall cannot withstand osmotic pressure, causing the bacterium to burst and die.

💡 How to Take cedopil 100mg/5ml dry syrup

Strength: Cefpodoxime proxetil oral suspension, 100 mg per 5 mL after reconstitution.

1Shake the bottle well before each use to ensure the medicine is mixed evenly.
2Use the measuring cup or syringe provided with the medicine to measure the correct dose.
3Take this medicine with food to improve absorption and reduce stomach upset.
4Swallow the suspension directly; do not mix with large amounts of liquid unless instructed.
5If you are also taking antacids or iron supplements, take them at least 2 hours before or after this medicine.
6Complete the full course as prescribed, even if you feel better after a few days.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 100 mg to 200 mg every 12 hours, depending on the type and severity of the infection. For example, for respiratory tract infections, 200 mg every 12 hours may be used. For uncomplicated urinary tract infections, 100 mg every 12 hours is common. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Always follow your doctor's prescription.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing based on the child's age, weight, and the specific infection.
Elderly DosageElderly patients may have reduced renal function, which can affect the elimination of this medicine. Dose adjustment may be necessary based on renal function. Your doctor will determine the appropriate dose.
Renal ImpairmentIn patients with renal impairment, the dose of this medicine should be adjusted. For creatinine clearance (CrCl) 30-49 mL/min, the dose may be given every 24 hours instead of every 12 hours. For CrCl 15-29 mL/min, the dose may be given every 24 hours and reduced. For CrCl <15 mL/min, the dose may be given every 48 hours. Dose must be individualized by a qualified clinician.
Hepatic ImpairmentNo specific dose adjustment is recommended for patients with hepatic impairment alone. However, use with caution and monitor liver function if there is concurrent renal impairment or severe liver disease.
Maximum Daily DoseThe maximum recommended daily dose is 400 mg (as cefpodoxime) for adults with normal renal function. For children, the maximum dose should not exceed 400 mg per day.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Increases absorption and reduces stomach upset.
Antacids
Avoid within 2 hours
Reduces absorption of cefpodoxime.
Iron supplements
Avoid within 2 hours
Reduces absorption of cefpodoxime.

⏰ What to Do If You Miss a Dose

📌 Less than 6 hours have passed since the missed dose
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than 6 hours have passed since the missed dose
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of cedopil 100mg/5ml dry syrup

✅ Common Side Effects

Diarrhea (Common (5-10%))
Usually resolves on its own. Stay hydrated. Consult doctor if severe or persistent.
Nausea (Common (5-10%))
Take with food to reduce nausea. Consult doctor if it persists.
Stomach pain (Common (5-10%))
Take with food. If pain is severe, contact your doctor.
Headache (Common (5-10%))
Usually resolves. Rest and hydration may help. Consult if severe.
Vaginal yeast infection (Uncommon (1-5%))
Consult doctor for appropriate antifungal treatment.

🚨 Serious Side Effects

Clostridium difficile-associated diarrhea (Rare (<0.1%))
Seek immediate medical attention if you develop severe, persistent diarrhea, abdominal pain, or fever.
Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency help if you experience rash, itching, swelling of face/lips/throat, difficulty breathing, or dizziness.
Stevens-Johnson syndrome (Very rare (<0.01%))
Seek immediate medical attention if you develop skin rash, blisters, or peeling skin.
Blood disorders (e.g., neutropenia, thrombocytopenia) (Rare (<0.1%))
Report unusual bruising, bleeding, or signs of infection to your doctor.
Liver enzyme elevation (Uncommon (1-5%))
Usually reversible. Your doctor may monitor liver function if you have pre-existing liver disease.

⚠️ Rare Side Effects

Seizures
Seek immediate medical attention.
Interstitial nephritis
Report decreased urine output, swelling, or fatigue to your doctor.
Hemolytic anemia
Seek medical attention if you experience unusual tiredness, pale skin, or jaundice.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Probenecid Moderate
Antacids Moderate
H2 blockers Moderate
Proton pump inhibitors Moderate
Oral contraceptives Minor
Iron supplements Minor

🚨 Major Interactions

  • Warfarin
  • Probenecid

⚡ Moderate Interactions

  • Antacids (e.g., aluminum/magnesium hydroxide)
  • H2 blockers (e.g., ranitidine)
  • Proton pump inhibitors (e.g., omeprazole)

🍷 Alcohol Interaction

Alcohol does not directly interact with cefpodoxime, but it can worsen stomach upset and dizziness. It is advisable to avoid alcohol while taking this medicine, especially if you have an infection.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to cefpodoxime, other cephalosporins, or penicillins","Previous severe allergic reaction to beta-lactam antibiotics","Use in patients with carnitine deficiency (due to pivalate component in some formulations, but not applicable to this syrup)"]

⚠️ Warnings & Precautions

["Before starting this medicine, inform your doctor if you are allergic to penicillin or other antibiotics.","Use with caution in patients with kidney disease; dose adjustment may be needed.","Prolonged use may lead to overgrowth of non-susceptible organisms, including fungi.","If severe diarrhea occurs, consider Clostridium difficile-associated diarrhea and seek medical advice.","Do not use this medicine for viral infections like the common cold or flu.","Complete the full course as prescribed, even if you feel better, to prevent resistance.","Shake the bottle well before each dose to ensure uniform suspension.","Use a calibrated measuring device for accurate dosing; a household spoon may not be accurate."]

🤱 Lactation Safety

Cefpodoxime is excreted in human breast milk in low concentrations. It is generally considered safe during breastfeeding, but consult your doctor to weigh the benefits and risks. Monitor the infant for diarrhea or thrush.

💊 Overdose Management

Overdose of cefpodoxime may cause nausea, vomiting, diarrhea, and abdominal pain. In case of overdose, seek immediate medical attention. Treatment is symptomatic and supportive. Hemodialysis may be considered in severe cases, especially in patients with renal impairment.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop early. Shake the bottle well before each use to ensure the medicine is evenly mixed. Use a proper measuring device to get the correct dose. Inform your doctor if you have kidney problems, allergies to antibiotics, or a history of gastrointestinal disease. Avoid taking antacids or iron supplements within 2 hours of this medicine, as they can reduce its absorption. If you are pregnant or breastfeeding, consult your doctor before using this medicine.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more likely to have reduced kidney function, which can affect the elimination of this medicine. Dose adjustment may be necessary. They may also be more susceptible to side effects such as diarrhea and superinfections. Monitor closely.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. It is generally considered safe in pregnancy (Category B), but should be used only if clearly needed. Discuss any concerns with your healthcare provider.

🏥 Post-Surgery Considerations

This medicine may be prescribed to prevent or treat surgical site infections. Follow your surgeon's instructions regarding dosing and duration. Inform your surgeon if you are taking any other medications.

🦷 Dental Procedures

This medicine may be used to treat dental infections or as prophylaxis before dental procedures in certain patients. Inform your dentist if you are taking this medicine or have any allergies to antibiotics.

💚 Lifestyle Tips for Better Results

🏃
Stay well hydrated to help your body fight the infection.
🥗
Get plenty of rest to support your immune system.
😴
Eat a balanced diet rich in fruits and vegetables.
💧
Practice good hand hygiene to prevent the spread of infection.
🧘
Avoid close contact with others while you are contagious.
🌞
Complete the full course of antibiotics even if you feel better.

🏋️ Exercise Considerations

You can continue light exercise if you feel up to it, but avoid strenuous activities if you have fever or fatigue. Listen to your body and rest when needed.

🥗 Diet Recommendations

Include probiotic-rich foods like yogurt to help maintain healthy gut flora.
Stay hydrated with water and clear fluids.
Avoid spicy and greasy foods if you have stomach upset.
Eat small, frequent meals if you have nausea.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or fatigue in some people. If you experience these effects, avoid driving or operating heavy machinery until you know how the medicine affects you. Most people can continue their normal activities, but rest is important for recovery.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor, even if you feel better. Stopping early can lead to a relapse of the infection and promote antibiotic resistance. If you experience severe side effects, contact your doctor immediately; they will advise whether to stop or switch to another antibiotic.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended unless prescribed for a specific chronic infection. Prolonged use may lead to antibiotic resistance and superinfections such as oral thrush or Clostridium difficile-associated diarrhea. Regular monitoring of kidney and liver function may be advised if used for extended periods.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Probiotics

Can help prevent antibiotic-associated diarrhea by restoring gut flora.

Evidence: Moderate
Symptomatic treatment

Use of pain relievers and fever reducers to manage symptoms while the antibiotic takes effect.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine does not interact with vaccines. However, if you are scheduled to receive a live vaccine, consult your doctor, as antibiotics may affect the immune response to certain vaccines.

📦 Storage Guide

✅ DO

Store dry powder at room temperature (15-30°C)

❌ DON'T

Do not refrigerate the dry powder.

✅ DO

After reconstitution, store in refrigerator (2-8°C)

❌ DON'T

Do not freeze the suspension.

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers.

✅ DO

Discard reconstituted suspension after 14 days

❌ DON'T

Do not use beyond the expiry date.

✈️ Traveling with This Medicine

When traveling with this medicine, carry it in its original packaging along with a copy of your prescription. Keep the dry powder at room temperature and protect it from direct sunlight. If you have already reconstituted the suspension, store it in a cool place or refrigerator if available. For air travel, keep it in your carry-on luggage. Check customs regulations for carrying prescription medicines in your destination country. If crossing time zones, adjust dosing times gradually to maintain even intervals, but consult your doctor for specific advice.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 5-year-old child with acute otitis media
The child was prescribed this medicine for an ear infection. The parents were advised to give it with food and to complete the 10-day course. After 3 days, the child's ear pain and fever improved significantly. The parents noted that giving the medicine with a small snack helped prevent stomach upset.
💡 Lesson: Taking the antibiotic with food improves tolerability and absorption. Completing the full course is essential to prevent recurrence.
👤 A 35-year-old adult with community-acquired pneumonia
The patient was started on this medicine twice daily. They were reminded not to take antacids within 2 hours of the dose. By day 4, cough and fever had subsided. The patient completed the 7-day course and recovered fully without complications.
💡 Lesson: Adhering to dosing intervals and avoiding interacting substances ensures optimal efficacy.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling better within 24-48 hours, but it is important to complete the full course as prescribed.

Q: Can I take it with food?

A: Yes, taking it with food improves absorption and reduces stomach upset.

Q: What if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Q: Is it safe for children?

A: It can be used in children, but the dose must be determined by a pediatrician based on the child's weight and the infection.

Q: Can I drink alcohol while taking it?

A: It is best to avoid alcohol as it may worsen side effects like stomach upset and dizziness.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine with milk?
  • Will it affect my birth control pills?
  • Can I take it if I have a penicillin allergy?
  • How long does it take to cure an infection?
  • What should I do if I miss a dose?
  • Can I take it for a cold?

🔄 Substitutes for cedopil 100mg/5ml dry syrup

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Antibiotics can cure viral infections like the common cold.
    Fact: This medicine is effective only against bacterial infections. It does not treat viral infections.
  • Myth: You can stop taking the antibiotic once you feel better.
    Fact: You must complete the full course as prescribed to prevent the infection from returning and to avoid antibiotic resistance.
  • Myth: Antibiotics weaken the immune system.
    Fact: Antibiotics do not weaken the immune system; they target bacteria. However, they can disrupt normal flora, which may lead to secondary infections.

🔄 Alternative Options

Generic Alternatives

  • Cefpodoxime proxetil oral suspension 100 mg/5 mL

Brand Alternatives

  • Addpod syrup

📊 Comparison with Similar Medicines

[{"medicine":"Cefpodoxime","class":"Third-generation cephalosporin","spectrum":"Broad-spectrum","dosing":"Twice daily","notes":"Good for respiratory and urinary infections."},{"medicine":"Cefixime","class":"Third-generation cephalosporin","spectrum":"Broad-spectrum","dosing":"Once or twice daily","notes":"Similar spectrum, but less active against Staphylococcus."},{"medicine":"Amoxicillin-clavulanate","class":"Penicillin + beta-lactamase inhibitor","spectrum":"Broad-spectrum","dosing":"Twice or three times daily","notes":"More active against anaerobes, but higher risk of diarrhea."}]

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