cdoxin 50mg injection - Uses, Price, Side Effects & Substitutes
What is cdoxin 50mg injection used for?
Adriamycin (Doxorubicin) is used to treat ANTI NEOPLASTICS. It contains Doxorubicin (Plain) (50mg), which Intercalates between DNA base pairs, inhibits topoisomerase II, and generates fr. Always consult your doctor before use. Take as prescribed.
- Generic Name: Doxorubicin
- Manufacturer: Health Biotech Limited
- Form: Allopathy
- Pregnancy Category: D
- Prescription Required: Yes
๐ cdoxin 50mg injection Uses & Benefits
Breast cancer, ovarian cancer, bladder cancer, thyroid cancer, gastric cancer, Hodgkin's lymphoma, non-Hodgkin's lymphoma, multiple myeloma, sarcoma, acute lymphoblastic leukemia, acute myeloid leukemia.
Off-label uses: Hepatocellular carcinoma, endometrial cancer, Wilms tumor, Ewing sarcoma.
๐ Drug Information
| Generic Name(s) | Doxorubicin |
| Brand Name | Adriamycin |
| Manufacturer | Health Biotech Limited |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | Alkaloids-cytotoxic agents |
| Route of Administration | Intravenous (IV) only; avoid intramuscular or subcutaneous. |
| Storage | Store at 2-8ยฐC. Protect from light. Reconstituted solution stable for 24 hours at room temperature. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Intercalates between DNA base pairs, inhibits topoisomerase II, and generates free radicals leading to DNA damage and cell death.
Mechanism Steps
๐ก How to Take cdoxin 50mg injection
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of cdoxin 50mg injection
โ Common Side Effects
- Nausea
- vomiting
- alopecia
- myelosuppression
- mucositis
- stomatitis
- red urine
๐จ Serious Side Effects
- Cardiomyopathy
- congestive heart failure
- severe myelosuppression
- secondary leukemia
- tumor lysis syndrome
- extravasation necrosis
โ ๏ธ Rare Side Effects
- Hemolytic uremic syndrome
- pulmonary fibrosis
- hepatic veno-occlusive disease
- anaphylaxis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Cyclophosphamide | Major | Increased cardiotoxicity risk |
| Trastuzumab | Major | Increased cardiotoxicity risk |
| Paclitaxel | Major | Increased myelosuppression |
| Verapamil | Moderate | Increased doxorubicin accumulation |
| Dexrazoxane | Moderate | Reduced cardiotoxicity (protective) |
| Phenobarbital | Moderate | Increased metabolism and reduced efficacy |
| Digoxin | Minor | Decreased digoxin absorption |
| Heparin | Minor | Incompatibility in solution |
๐จ Major Interactions
- Cyclophosphamide
- Trastuzumab
- Paclitaxel
- Radiation therapy
โก Moderate Interactions
- Verapamil
- Dexrazoxane
- Phenobarbital
โน๏ธ Minor Interactions
- Digoxin
- Heparin
๐ฝ๏ธ Food Interactions
No significant food interactions.
๐ท Alcohol Interaction
Avoid alcohol due to potential hepatotoxicity.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Severe hepatic impairment, severe myelosuppression, pre-existing cardiomyopathy, hypersensitivity, pregnancy.
๐ Monitoring Parameters
CBC with differential, liver function tests, cardiac function (LVEF), renal function, uric acid levels.
๐คฑ Lactation Safety
Contraindicated; excreted in breast milk.
๐ Overdose Management
Supportive care; severe myelosuppression may require G-CSF and antibiotics. Dexrazoxane may be used for extravasation or cardiotoxicity.
โฐ Missed Dose
Do not double dose. Contact physician for rescheduling.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for cdoxin 50mg injection
View AllAlternative brands with exact same active ingredient (Doxorubicin (Plain) (50mg)):
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metodox 50mg injectionNeon Laboratories Ltd โน211.90 82.3% CHEAPER
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duxocin 50 injectionZydus Cadila โน226.53 81% CHEAPER
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stridox 50mg injectionMylan Pharmaceuticals Pvt Ltd โน250.00 79.1% CHEAPER
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doxorex 50mg injectionSamarth Life Sciences Pvt Ltd โน262.10 78.1% CHEAPER
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doxilyd 50mg injectionCelon Laboratories Ltd โน523.81 56.2% CHEAPER
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adronex rd 50mg injectionVhb Life Sciences Inc โน654.76 45.2% CHEAPER
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doxotero 50mg injectionHetero Drugs Ltd โน686.81 42.5% CHEAPER
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doxutec 50mg injectionUnited Biotech Pvt Ltd โน749.00 37.3% CHEAPER
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adrib injectionAdley Formulations โน815.63 31.7% CHEAPER
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adrim 50mg injectionFresenius Kabi India Pvt Ltd โน847.88 29% CHEAPER
Medical Note: Always consult your doctor before switching medications.