castophene tablet - Phenolphthalein (0.19gm) medicine

Castophene Tablet: Complete Medicine Guide

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🏭 Technopharm Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 20, 2026
🤰 Pregnancy Category Phenolphthalein is not recommended for use during pregnancy unless specifically advised by a clinician. Safer alternatives are usually preferred. Pregnant women should consult their doctor before using this medicine. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Limited; phenolphthalein is an older laxative with safety concerns for long-term use.
Reviewed by
SaathiMed Expert Panel | Sep 20, 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain or cramping
  • Persistent vomiting or inability to keep fluids down
  • Signs of dehydration such as dizziness, dry mouth, or reduced urine output
  • Swelling of the face, lips, or throat, or difficulty breathing
  • Severe diarrhea lasting more than 24 hours
  • Yellowing of the skin or eyes
  • Unusual bruising or bleeding

If experiencing severe symptoms, call emergency services immediately.

What is castophene tablet used for?

This medicine contains phenolphthalein, a stimulant laxative used for short-term relief of occasional constipation. It works by stimulating the colon to move stool and is usually taken at bedtime. It should not be used for more than one to two weeks without medical advice.

  • Generic Name: Phenolphthalein
  • Manufacturer: Technopharm Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 castophene tablet के बारे में (Hindi Summary)

उपयोग: यह दवा फिनोल्फ्थेलिन नामक सक्रिय तत्व से बनी है और यह एक उत्तेजक रेचक (stimulant laxative) है। इसका उपयोग कभी-कभार होने वाले कब्ज के अल्पकालिक उपचार के लिए किया जाता है। यह आंतों की गति को बढ़ाकर और मल को नरम करके मल त्याग को आसान बनाती है। यह दवा आमतौर पर रात को सोने से पहले ली जाती है ताकि सुबह के समय इसका असर हो। इसका उपयोग केवल कुछ दिनों तक ही करना चाहिए, लंबे समय तक नहीं। यदि कब्ज बार-बार हो रहा है या ठीक नहीं हो रहा है, तो डॉक्टर से सलाह लें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में पेट में ऐंठन, जी मिचलाना, उल्टी, दस्त और पेशाब का गुलाबी या लाल रंग का होना शामिल है। कुछ लोगों को चक्कर आना, त्वचा पर दाने या गुदा के आसपास जलन भी हो सकती है। गंभीर दुष्प्रभावों में तेज दस्त के कारण निर्जलीकरण, इलेक्ट्रोलाइट असंतुलन और एलर्जी प्रतिक्रिया शामिल हैं। यदि आपको गंभीर पेट दर्द, मल में खून, बेहोशी या सांस लेने में कठिनाई हो, तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर या फार्मासिस्ट के निर्देशानुसार ही लें। अपनी मर्जी से खुराक या बार-बार सेवन न बढ़ाएं। इसका उपयोग केवल कुछ दिनों तक ही करें, आमतौर पर एक से दो सप्ताह से अधिक नहीं। गोली को पूरे गिलास पानी के साथ निगलें, चबाएं नहीं। रात को सोने से पहले लेना बेहतर होता है। यदि आपको गंभीर पेट दर्द, उल्टी, आंतों में रुकावट या सूजन की बीमारी है, तो यह दवा न लें। दस्त होने पर पानी और तरल पदार्थ अधिक मात्रा में लें। गर्भवती या स्तनपान कराने वाली महिलाएं बिना डॉक्टर की सलाह के इसका सेवन न करें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 castophene tablet Uses & Benefits

[{"condition":"Occasional constipation","description":"This medicine provides short-term relief of occasional constipation by stimulating bowel movements and softening the stool.","evidence":"Established for short-term use"},{"condition":"Bowel preparation before procedures","description":"In some settings, stimulant laxatives like phenolphthalein have been used as part of bowel cleansing regimens before certain diagnostic procedures, but only under direct medical supervision.","evidence":"Limited and procedure-specific"}]

Off-label uses: [{"condition":"Chronic idiopathic constipation","description":"Phenolphthalein is not recommended for chronic constipation because of safety concerns with long-term use, but it has occasionally been used off-label in adults when other options have failed and only under close medical supervision.","evidence":"Limited and not recommended for routine use"}]

Primary treatment for: Constipation

Also treats: Bowel preparation before procedures

📋 Drug Information

Generic Name(s)Phenolphthalein
Brand NameCastophene Tablet
ManufacturerTechnopharm Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassStimulant laxatives/purgative
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C in a dry place, away from direct sunlight and moisture. Keep the tablets in their original container.
Shelf LifeRefer to the expiry date printed on the pack. Do not use after the expiry date.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at bedtime with a full glass of water so that the effect occurs in the morning.
2
Use this medicine only for short-term relief of occasional constipation, not for daily bowel habits.
3
Do not combine this medicine with other laxatives unless your doctor specifically advises it.
4
Drink plenty of fluids throughout the day to prevent dehydration, especially if diarrhea occurs.
5
Stop the medicine and consult a doctor if constipation persists beyond one to two weeks.
6
Report any unusual bleeding, bruising, or skin rash to your doctor immediately.
7
Avoid alcohol while taking this medicine because it can worsen dehydration.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Occasional constipation
This medicine is commonly prescribed for this.
Likely Use
Chronic constipation
This medicine is not recommended for long-term use.
Not Primary
Fever
This medicine is not a fever reducer.
Not Primary
Abdominal pain of unknown cause
This medicine should not be used without a diagnosis.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionPhenolphthalein is partially absorbed from the small intestine after oral administration. The unabsorbed portion passes into the colon, where it exerts its laxative effect. The exact extent of absorption is not well established from the available information.
DistributionNot established from the available information.
Protein BindingNot established from the available information.
MetabolismPhenolphthalein undergoes some metabolism in the liver, but the exact metabolic pathways are not well established from the available information.
Half-LifeNot established from the available information.
ExcretionPhenolphthalein and its metabolites are excreted mainly in the urine and feces. The pink or red discoloration of urine that some people notice is due to the excretion of phenolphthalein or its metabolites.
BioavailabilityNot established from the available information.
Onset of ActionThe laxative effect of this medicine usually begins within 6 to 12 hours after taking the tablet, although this can vary between individuals.
Peak Plasma TimeNot established from the available information.
Duration of ActionThe effect of a single dose generally lasts for several hours to a day, depending on the individual and the severity of constipation.

How It Works

This medicine works as a stimulant laxative. After oral intake, phenolphthalein is partly absorbed and partly remains in the colon, where it directly irritates the mucosal lining and stimulates the intramural nerve plexuses of the large intestine. This stimulation increases colonic motility and reduces water absorption, leading to a softer stool and an urge to defecate. The action is mainly on the colon rather than the small intestine, which is why the effect is usually felt several hours after taking the tablet.

Mechanism Steps

1
Ingestion and partial absorption: After the tablet is swallowed, phenolphthalein is partly absorbed from the gastrointestinal tract and partly remains in the colon.
2
Colonic mucosal irritation: The portion of the medicine that reaches the colon irritates the mucosal lining and stimulates the enteric nerve plexuses.
3
Increased motility: Stimulation of the enteric nerves increases propulsive contractions of the colon, moving stool toward the rectum.
4
Reduced water absorption: The medicine reduces the reabsorption of water and electrolytes from the colon, keeping the stool soft and easier to pass.
5
Defecation: The combined effect of increased motility and softer stool produces the urge to defecate, usually within several hours.

💡 How to Take castophene tablet

Strength: Immediate-release tablet containing phenolphthalein 0.19 gm (190 mg).

1Take the tablet by mouth with a full glass of water.
2Swallow the tablet whole; do not crush or chew it.
3Take it at bedtime for a morning bowel movement.
4Do not take more than the recommended dose.
5Drink plenty of fluids throughout the day.
6If you have severe abdominal pain, stop and consult a doctor.

Dosage Information

Adult DosageThe usual adult dose of this medicine is one tablet taken orally at bedtime, but the exact dose and frequency must be individualized by a qualified clinician based on the severity of constipation, age, weight, and kidney and liver function. Do not exceed the dose recommended by your doctor. This medicine is intended for short-term use only, generally for no more than one to two weeks. If constipation does not improve, consult a doctor rather than increasing the dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine, especially dehydration and electrolyte imbalance. Use with caution and only under medical supervision. The dose should be individualized by a clinician.
Renal ImpairmentUse with caution in patients with kidney disease. Dose adjustment may be needed, and monitoring of kidney function and electrolytes is advised. Consult a doctor before use.
Hepatic ImpairmentUse with caution in patients with liver disease. Dose adjustment may be needed. Consult a doctor before use.
Maximum Daily DoseThe maximum daily dose should not exceed the dose recommended by your doctor. Do not take more than one tablet in 24 hours unless specifically instructed by a clinician.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with a meal or snack if stomach upset occurs
Reduces nausea and abdominal discomfort.
Water
Drink a full glass with the tablet
Helps the tablet dissolve and prevents dehydration.
High-fiber foods
Include in your diet
Helps prevent constipation naturally.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of castophene tablet

✅ Common Side Effects

Abdominal cramps (Common)
Cramps often settle as the bowel movement occurs. If they are severe or persistent, contact your doctor.
Nausea (Common)
Take the tablet with a small amount of food or water if nausea occurs. If it continues, speak to your doctor.
Diarrhea (Common)
Drink plenty of fluids to avoid dehydration. If diarrhea is severe or lasts more than a day, stop the medicine and seek medical advice.
Pink or red discoloration of urine (Common)
This is a known effect and usually resolves on its own. No action is needed unless you are concerned.
Vomiting (Uncommon)
Stop the medicine and contact your doctor if vomiting is persistent or severe.

🚨 Serious Side Effects

Severe diarrhea with dehydration (Uncommon)
Stop the medicine and seek medical attention if you have severe diarrhea, dizziness, or reduced urine output.
Electrolyte imbalance (Uncommon)
Seek medical advice if you experience muscle weakness, palpitations, or confusion after prolonged or excessive use.
Allergic reaction (Rare)
Seek emergency care immediately if you develop swelling of the face, lips, or throat, or difficulty breathing.
Severe skin reaction (Very rare)
Stop the medicine and seek urgent medical care if you develop a spreading rash, blisters, or peeling skin.
Laxative dependence (Uncommon with prolonged use)
Do not use this medicine for more than the recommended short period. Consult a doctor if constipation persists.

⚠️ Rare Side Effects

Blood disorders
Seek medical attention if you notice unusual bruising, bleeding, or persistent fatigue.
Protein-losing enteropathy
Consult a doctor if you develop persistent diarrhea and swelling of the legs or abdomen.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Diuretics Major
Digoxin Major
Other laxatives Major
Corticosteroids Moderate
Antacids Moderate
Oral contraceptives Minor

🚨 Major Interactions

  • Other stimulant laxatives
  • Diuretics
  • Digoxin

⚡ Moderate Interactions

  • Corticosteroids
  • Antacids

🍷 Alcohol Interaction

Alcohol may worsen dehydration and electrolyte imbalance caused by this medicine. It is best to avoid alcohol while taking this medicine, especially if diarrhea occurs.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to phenolphthalein or any component of the tablet","Intestinal obstruction or paralytic ileus","Acute abdominal pain of unknown cause","Severe inflammatory bowel disease such as ulcerative colitis or Crohn's disease","Severe dehydration or electrolyte imbalance","Children unless specifically prescribed by a pediatrician","Pregnancy and breastfeeding unless approved by a doctor"]

⚠️ Warnings & Precautions

["Use this medicine only for short-term relief of occasional constipation.","Do not use for more than one to two weeks without medical advice.","Stop the medicine and consult a doctor if constipation persists or worsens.","Avoid using other laxatives at the same time unless advised.","Drink plenty of fluids to prevent dehydration.","Report any unusual bleeding, bruising, or skin rash to your doctor.","People with heart, kidney, or liver disease should use this medicine only under medical supervision.","Keep out of reach of children."]

🤱 Lactation Safety

It is not known whether phenolphthalein passes into breast milk in significant amounts. Because of potential risks to the infant, breastfeeding women should avoid this medicine unless a doctor has specifically recommended it.

💊 Overdose Management

Overdose with this medicine can cause severe diarrhea, vomiting, abdominal pain, dehydration, and electrolyte imbalance. If you suspect an overdose, stop the medicine and seek immediate medical attention. Treatment is supportive and may include intravenous fluids and electrolyte replacement. Do not try to treat yourself at home.

⏰ Missed Dose

If you miss a dose of this medicine, take it as soon as you remember, unless it is almost time for your next dose. If it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Take this medicine exactly as directed by your doctor or pharmacist, and do not increase the dose or frequency on your own. Use it only for short-term relief of occasional constipation, generally for no more than one to two weeks unless a clinician advises otherwise. Swallow the tablet whole with a full glass of water, preferably at bedtime so that the effect occurs in the morning. Do not take this medicine if you have severe abdominal pain, vomiting, intestinal obstruction, or inflammatory bowel disease. Avoid using other laxatives at the same time unless your doctor approves. Drink plenty of fluids throughout the day to prevent dehydration, especially if diarrhea occurs. Stop the medicine and contact your doctor if you notice blood in the stool, severe cramps, persistent diarrhea, dizziness, or a rash. Keep this medicine out of the reach of children, and store it in its original container away from heat and moisture. If you are pregnant, planning pregnancy, or breastfeeding, speak to your doctor before using this medicine.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more prone to dehydration and electrolyte imbalance from this medicine. Use with caution and only under medical supervision. Monitor fluid intake and kidney function.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, avoid this medicine unless specifically advised by a doctor. Discuss safer alternatives for constipation with your healthcare provider.

🏥 Post-Surgery Considerations

After surgery, bowel movements may be sluggish. Do not use this medicine without consulting your surgeon, as it may interfere with postoperative care or mask complications.

🦷 Dental Procedures

There are no specific dental precautions with this medicine. However, inform your dentist about all medicines you are taking before any procedure.

💚 Lifestyle Tips for Better Results

🏃
Drink at least 8 to 10 glasses of water daily.
🥗
Include plenty of fiber in your diet through fruits, vegetables, and whole grains.
😴
Exercise regularly to stimulate bowel movements.
💧
Establish a regular toilet routine, preferably after breakfast.
🧘
Do not ignore the urge to have a bowel movement.
🌞
Manage stress through relaxation techniques.

🏋️ Exercise Considerations

This medicine may cause dizziness or dehydration, especially if diarrhea occurs. Avoid strenuous exercise if you feel weak or dizzy. Drink plenty of fluids before and after exercise.

🥗 Diet Recommendations

Include high-fiber foods such as fruits, vegetables, and whole grains.
Drink plenty of water throughout the day.
Limit processed and low-fiber foods.
Avoid excessive caffeine and alcohol.
Eat regular meals to promote regular bowel habits.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or frequent bowel movements, which can affect your ability to drive or operate machinery. Avoid driving if you feel dizzy. Plan your work schedule around the expected time of bowel movement, usually in the morning after a bedtime dose.

🛑 When to Stop This Medicine

Stop this medicine if you develop severe diarrhea, abdominal pain, blood in the stool, or signs of an allergic reaction. Do not use it for more than one to two weeks without medical advice. If constipation persists, consult a doctor before continuing.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended. Prolonged use can lead to laxative dependence, chronic diarrhea, dehydration, low potassium levels, and protein-losing enteropathy. If constipation persists, the underlying cause should be evaluated by a doctor rather than continuing this medicine.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Dietary fiber and fluid intake

Increasing fiber and water intake can help relieve and prevent constipation naturally.

Evidence: Well-established
Regular physical activity

Exercise helps stimulate bowel movements and improve overall digestive health.

Evidence: Well-established
Osmotic laxatives

Alternatives such as lactulose or polyethylene glycol may be safer for longer-term use.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, if you are unwell with severe diarrhea or dehydration, it is better to postpone vaccination until you recover.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If you are crossing time zones, continue taking it at bedtime according to your usual routine, but do not take extra doses. Keep it in your hand luggage if you need it during the journey. Check local customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 38-year-old woman with occasional constipation due to travel and dietary changes
She was prescribed this medicine for short-term relief. She took one tablet at bedtime with water and had a comfortable bowel movement the next morning. She stopped the medicine after three days and improved her fluid and fiber intake.
💡 Lesson: Short-term use of this medicine can provide relief, but lifestyle changes are important for long-term bowel health.
👤 A 62-year-old man with chronic constipation who self-medicated with this medicine daily for several weeks
He developed persistent diarrhea, weakness, and dizziness. Blood tests showed low potassium levels. He was advised to stop the medicine and was treated with fluids and electrolyte replacement.
💡 Lesson: Prolonged use of this medicine can cause serious electrolyte problems. It should never be used as a daily habit without medical supervision.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually produces a bowel movement within 6 to 12 hours after taking it.

Q: Can I take this medicine every day?

A: No, this medicine is only for short-term use. Prolonged daily use can cause dependence and electrolyte problems.

Q: Is this medicine safe during pregnancy?

A: It is not recommended during pregnancy unless specifically advised by a doctor. Safer alternatives are usually preferred.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember unless it is almost time for the next dose. Do not double dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🛑 Myths vs. Facts

  • Myth: This medicine is safe for daily use to treat chronic constipation.
    Fact: This medicine is only for short-term relief. Prolonged use can cause dependence and electrolyte problems.
  • Myth: Taking more tablets will work faster.
    Fact: Taking more than the recommended dose can cause severe diarrhea and dehydration without speeding up relief.
  • Myth: This medicine is safe for everyone.
    Fact: It is not safe for people with intestinal obstruction, severe inflammatory bowel disease, or during pregnancy without medical advice.

🔄 Alternative Options

Generic Alternatives

  • Phenolphthalein 190 mg tablet

📊 Comparison with Similar Medicines

[{"medicine":"This medicine (phenolphthalein)","class":"Stimulant laxative","onset":"6-12 hours","common_use":"Occasional constipation","notes":"Short-term use only"},{"medicine":"Bisacodyl","class":"Stimulant laxative","onset":"6-12 hours","common_use":"Occasional constipation","notes":"Widely used alternative"},{"medicine":"Senna","class":"Stimulant laxative","onset":"6-12 hours","common_use":"Occasional constipation","notes":"Plant-derived alternative"}]

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