cartibone tablet - Diacerein (50mg) + Glucosamine Sulfate Potassium Chloride (750mg) medicine

cartibone tablet - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Superlative Healthcare ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 28, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 28, 2026

What is cartibone tablet used for?

Acerin GM Tablet (Diacerein + Glucosamine Sulfate Potassium Chloride) is used to treat PAIN ANALGESICS. It contains Diacerein (50mg) + Glucosamine Sulfate Potassium Chloride (750mg), which Diacerein: Inhibits interleukin-1 beta and matrix metalloproteinases; Glucosamin. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Diacerein + Glucosamine Sulfate Potassium Chloride
  • Manufacturer: Superlative Healthcare
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

๐Ÿ’Š cartibone tablet Uses & Benefits

Osteoarthritis, joint pain, cartilage degeneration.

Off-label uses: Rheumatoid arthritis, temporomandibular joint disorders.

๐Ÿ“‹ Drug Information

Generic Name(s)Diacerein + Glucosamine Sulfate Potassium Chloride
Brand NameAcerin GM Tablet
ManufacturerSuperlative Healthcare
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassPain Analgesics
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionDiacerein: Slowly absorbed after oral administration; Glucosamine: Well absorbed orally.
DistributionDiacerein: Highly distributed to tissues; Glucosamine: Distributed to articular cartilage and other tissues.
Protein BindingDiacerein: >90% bound to plasma proteins; Glucosamine: Not significantly bound.
MetabolismDiacerein: Metabolized in liver to active metabolite rhein; Glucosamine: Metabolized via hexosamine pathway.
Half-LifeDiacerein: ~4-5 hours (rhein ~8 hours); Glucosamine: ~1-2 hours.
ExcretionDiacerein: Renal and biliary; Glucosamine: Renal.
BioavailabilityDiacerein: ~35-56%; Glucosamine: ~25-44%.
Onset of ActionDiacerein: 2-4 weeks; Glucosamine: 2-6 weeks.
Peak Plasma TimeDiacerein: 2-4 hours; Glucosamine: 1-3 hours.
Duration of ActionDiacerein: Up to 24 hours; Glucosamine: Not well defined.

How It Works

Diacerein: Inhibits interleukin-1 beta and matrix metalloproteinases; Glucosamine: Stimulates proteoglycan synthesis and inhibits degradation.

Mechanism Steps

1Diacerein inhibits IL-1ฮฒ production and activity
2Reduces matrix metalloproteinase expression
3Decreases cartilage degradation

๐Ÿ’ก How to Take cartibone tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of cartibone tablet

โœ… Common Side Effects

  • Diarrhea
  • Nausea
  • Abdominal pain
  • Soft stools

๐Ÿšจ Serious Side Effects

  • Hepatotoxicity
  • Stevens-Johnson syndrome
  • Angioedema

โš ๏ธ Rare Side Effects

  • Allergic dermatitis
  • Thrombocytopenia
  • Interstitial nephritis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased INR and bleeding risk
Methotrexate Major Increased methotrexate toxicity
NSAIDs Moderate Additive GI irritation
Diuretics Moderate Reduced diuretic efficacy
Antacids Minor Reduced absorption of diacerein

๐Ÿšจ Major Interactions

  • Warfarin
  • Anticoagulants
  • Methotrexate

โšก Moderate Interactions

  • NSAIDs
  • Corticosteroids
  • Diuretics

โ„น๏ธ Minor Interactions

  • Antacids
  • H2 antagonists

๐Ÿฝ๏ธ Food Interactions

May be taken with food to reduce GI upset; food may decrease absorption rate.

๐Ÿท Alcohol Interaction

Avoid alcohol as it may increase risk of hepatotoxicity and GI bleeding.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity, severe renal impairment, pregnancy (diacerein), inflammatory bowel disease.

๐Ÿ“Š Monitoring Parameters

Liver function, renal function, INR if on warfarin, GI symptoms.

๐Ÿคฑ Lactation Safety

Not recommended; excretion in milk unknown.

๐Ÿ’Š Overdose Management

Symptomatic and supportive; induce vomiting or gastric lavage.

โฐ Missed Dose

Take as soon as remembered; skip if near next dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 28, 2026

๐Ÿ”— View Profile

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