Cardivas In 3.125/5 Tablet: A Comprehensive Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe dizziness or fainting
- Heart rate below 50 beats per minute
- Chest pain or difficulty breathing
- Sudden weight gain or swelling in legs
- Severe fatigue or weakness
- Yellowing of skin or eyes
- Decreased urine output
If experiencing severe symptoms, call emergency services immediately.
What is carloc i 3.125 tablet used for?
This medicine is a combination of Carvedilol and Ivabradine used to treat chronic heart failure. It works by slowing the heart rate and reducing the heart's workload, improving symptoms and reducing hospitalizations.
- Generic Name: Carvedilol + Ivabradine
- Manufacturer: Cipla Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 carloc i 3.125 tablet के बारे में (Hindi Summary)
उपयोग: यह दवा कैर्वेडिलोल और आइवाब्राडीन का संयोजन है, जिसका उपयोग पुरानी हृदय विफलता (क्रॉनिक हार्ट फेल्योर) के इलाज में किया जाता है। यह हृदय की गति को धीमा करती है और हृदय पर दबाव कम करती है, जिससे सांस फूलना, थकान और अन्य लक्षणों में सुधार होता है। यह दवा हृदय की कार्यक्षमता बढ़ाने और अस्पताल में भर्ती होने के जोखिम को कम करने में मदद करती है। इसे केवल हृदय रोग विशेषज्ञ के निर्देशन में ही लेना चाहिए।
साइड इफेक्ट्स: आम दुष्प्रभावों में चक्कर आना, थकान, सिरदर्द और निम्न रक्तचाप शामिल हैं। कुछ रोगियों में धीमी हृदय गति, धुंधली दृष्टि या पेट की गड़बड़ी हो सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि आपको बेहोशी, सीने में दर्द या सांस लेने में कठिनाई हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को हमेशा डॉक्टर के बताए अनुसार ही लें। डॉक्टर की सलाह के बिना इसे अचानक बंद न करें, क्योंकि इससे हृदय की स्थिति बिगड़ सकती है। जब तक आपको पता न चले कि यह दवा आप पर कैसा असर करती है, तब तक वाहन चलाने या भारी मशीनरी चलाने से बचें। अपने डॉक्टर को अन्य सभी दवाओं के बारे में बताएं जो आप ले रहे हैं। नियमित रूप से हृदय गति, रक्तचाप और गुर्दे की कार्यप्रणाली की जांच कराएं। शराब से बचें क्योंकि इससे दुष्प्रभाव बढ़ सकते हैं।
💊 carloc i 3.125 tablet Uses & Benefits
[{"condition":"Chronic heart failure with reduced ejection fraction","description":"Used to reduce symptoms, improve heart function, and decrease hospitalizations in patients with stable heart failure.","evidence":"Well-established"},{"condition":"Angina pectoris","description":"Carvedilol component helps reduce angina attacks by lowering heart rate and oxygen demand.","evidence":"Well-established"},{"condition":"Hypertension","description":"Carvedilol component helps lower blood pressure, though this combination is primarily for heart failure.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Inappropriate sinus tachycardia","description":"Ivabradine component may be used off-label to reduce elevated heart rate in patients without structural heart disease.","evidence":"Limited"},{"condition":"Postural orthostatic tachycardia syndrome (POTS)","description":"Ivabradine has been studied off-label for heart rate control in POTS, but evidence is limited.","evidence":"Limited"}]
Primary treatment for: Chronic heart failure with reduced ejection fraction
Also treats: Angina pectoris, Hypertension, Coronary artery disease
📋 Drug Information
| Generic Name(s) | Carvedilol + Ivabradine |
| Brand Name | Cardivas 3.125/5 Tablet |
| Manufacturer | Cipla Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Beta-blocker + If channel blocker |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Carvedilol is a non-selective beta-adrenergic blocker that also blocks alpha-1 receptors. It reduces heart rate, decreases myocardial contractility, and lowers peripheral vascular resistance, thereby reducing cardiac workload and oxygen demand. Ivabradine selectively inhibits the If (funny) current in the sinoatrial node, which slows the spontaneous depolarization of pacemaker cells, leading to a reduction in heart rate without affecting myocardial contractility or blood pressure. Together, they provide effective heart rate control and improve cardiac efficiency in heart failure.
Mechanism Steps
💡 How to Take carloc i 3.125 tablet
Strength: Tablet containing Carvedilol 3.125 mg and Ivabradine 5 mg.
Dosage Information
| Adult Dosage | The dose of this medicine is individualized by a qualified clinician based on the patient's condition, heart rate, blood pressure, and tolerance. Typically, treatment is started at a low dose and gradually increased over weeks. The usual maintenance dose may be one tablet twice daily, but this varies. Do not self-adjust the dose. Regular monitoring is required. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine, especially bradycardia and hypotension. Doses should be started low and titrated slowly with close monitoring. |
| Renal Impairment | In patients with renal impairment, carvedilol should be used with caution. Ivabradine does not require dose adjustment in mild to moderate renal impairment, but is contraindicated in severe renal impairment (CrCl < 15 mL/min). Consult your doctor for individualized dosing. |
| Hepatic Impairment | Carvedilol is contraindicated in severe hepatic impairment. Ivabradine should be used with caution in patients with hepatic impairment. Dose adjustment may be necessary. Consult your doctor. |
| Maximum Daily Dose | The maximum daily dose is determined by the prescribing clinician based on individual patient factors. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of carloc i 3.125 tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Verapamil | Major | |
| Clonidine | Major | |
| Ketoconazole | Major | |
| Digoxin | Moderate | |
| Salbutamol | Moderate | |
| Insulin | Moderate | |
| Antacids | Minor | |
| NSAIDs | Minor |
🚨 Major Interactions
- Verapamil and diltiazem
- Clonidine
- CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin)
⚡ Moderate Interactions
- Digoxin
- Beta-agonists (e.g., salbutamol)
- Insulin and oral hypoglycemics
🍷 Alcohol Interaction
Alcohol may enhance the blood pressure-lowering and heart rate-slowing effects of this medicine, leading to dizziness, fainting, or falls. It is advisable to avoid alcohol or limit intake significantly while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Severe bradycardia (heart rate < 50 bpm)","Sick sinus syndrome, sinoatrial block, or third-degree AV block (unless pacemaker present)","Severe hypotension (systolic BP < 90 mmHg)","Severe hepatic impairment","Acute decompensated heart failure","Hypersensitivity to carvedilol, ivabradine, or any component","Severe renal impairment (creatinine clearance < 15 mL/min)"]
⚠️ Warnings & Precautions
["Do not abruptly discontinue this medicine; taper gradually under medical supervision.","Use with caution in patients with asthma or COPD due to beta-blocking effects.","May mask symptoms of hypoglycemia in diabetic patients.","Avoid in patients with severe peripheral vascular disease.","Use with caution in patients with psoriasis or history of allergic reactions.","Regular monitoring of heart rate, blood pressure, and renal function is required.","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding."]
🤱 Lactation Safety
Not established from the available information. Carvedilol is excreted in breast milk. Ivabradine is also likely to be excreted in breast milk. Consult your doctor before breastfeeding.
💊 Overdose Management
Overdose may cause severe bradycardia, hypotension, heart failure, and cardiogenic shock. Seek immediate medical attention. Treatment is supportive and symptomatic, including atropine for bradycardia, intravenous fluids for hypotension, and in severe cases, temporary pacing or use of vasopressors. Gastric lavage may be considered if ingestion is recent.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Always take this medicine exactly as prescribed by your doctor. Do not stop or change the dose without medical advice, as sudden discontinuation can worsen your heart condition. Avoid driving or operating heavy machinery until you know how this medicine affects you. Inform your doctor about all other medications you are taking, especially those for blood pressure, heart rhythm, or depression. Regular monitoring of heart rate, blood pressure, and kidney function is essential. Avoid alcohol as it may increase side effects. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before taking this medicine.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more prone to bradycardia and hypotension. Start with a low dose and titrate slowly. Monitor renal function closely.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before taking this medicine. Both carvedilol and ivabradine should be used with caution during pregnancy. Your doctor may switch you to a safer alternative.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with anesthetic agents and affect heart rate and blood pressure during surgery. Do not stop the medicine without medical advice.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine, as it may cause dry mouth or interact with local anesthetics containing epinephrine. Your dentist may take precautions.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise until you know how this medicine affects you. It can cause dizziness or fatigue. Consult your doctor before starting any exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue, affecting your ability to drive or operate machinery. Avoid these activities until you know how it affects you. Inform your employer if your job involves such tasks.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience severe side effects, contact your doctor immediately for advice on dose adjustment or alternative treatment.
📅 Long-Term Use Effects
Long-term use of this medicine can improve heart function and reduce hospitalizations. Regular monitoring of heart rate, blood pressure, renal and hepatic function is necessary. Do not stop without medical advice.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet, exercise, and weight management can complement medicine for heart failure.
Evidence: Well-establishedSupervised exercise and education programs can improve heart function and quality of life.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Patients with heart failure should receive annual influenza and pneumococcal vaccinations as advised by their doctor. These vaccines can reduce the risk of respiratory infections that may worsen heart failure.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Keep it in your hand luggage to avoid loss. Store at room temperature and protect from extreme heat or moisture. If traveling across time zones, consult your doctor about adjusting dosing times. Check local customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within a few hours, but full benefits may take several weeks. Your doctor will monitor your progress and adjust the dose as needed.
A: No, do not stop without consulting your doctor. Stopping suddenly can worsen your heart condition.
A: Take it as soon as you remember. If it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
🤔 Common Patient Concerns
🔄 Substitutes for carloc i 3.125 tablet
View AllAlternative brands with exact same active ingredient:
-
ivanode c 3.125mg/5mg tabletTorrent Pharmaceuticals Ltd ₹196.00 7.2% COSTLIER
-
irban beta 3.125mg/5mg tabletGlenmark Pharmaceuticals Ltd ₹196.88 7.7% COSTLIER
-
cardivas in 3.125/5 tabletSun Pharmaceutical Industries Ltd ₹204.38 11.8% COSTLIER
-
ivabrad c 3.125mg/5mg tabletLupin Ltd ₹272.06 48.8% COSTLIER
-
ivabid cv 3.125 tabletAbbott Healthcare Private Limited ₹277.41 51.7% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure heart failure completely.
Fact: This medicine helps manage symptoms and improve heart function but does not cure heart failure. It must be continued as prescribed. - Myth: I can stop taking this medicine once I feel better.
Fact: Stopping suddenly can worsen your condition. Always consult your doctor before making any changes.
🔄 Alternative Options
Generic Alternatives
- Carvedilol + Ivabradine combination generics may be available. Consult your pharmacist.
Brand Alternatives
- Cardivas IN 3.125/5 Tablet