cardiolol 5mg tablet - Nebivolol (5mg) medicine

cardiolol 5mg tablet - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Cubit Healthcare ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 28, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 28, 2026

What is cardiolol 5mg tablet used for?

Asivol 5mg Tablet (Nebivolol) is used to treat CARDIAC. It contains Nebivolol (5mg), which Selective beta-1 adrenergic receptor antagonist; also has nitric oxide-mediated . Always consult your doctor before use. Take as prescribed.

  • Generic Name: Nebivolol
  • Manufacturer: Cubit Healthcare
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

๐Ÿ’Š cardiolol 5mg tablet Uses & Benefits

Hypertension, chronic heart failure (stable, mild to moderate).

Off-label uses: Migraine prophylaxis, essential tremor, performance anxiety.

๐Ÿ“‹ Drug Information

Generic Name(s)Nebivolol
Brand NameAsivol 5mg Tablet
ManufacturerCubit Healthcare
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassBeta blocker- Cardioselective
Route of AdministrationOral
StorageStore at 20-25ยฐC (68-77ยฐF); protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after oral administration; food does not affect absorption.
DistributionWidely distributed; crosses blood-brain barrier.
Protein BindingApproximately 98% bound to plasma proteins, primarily albumin.
MetabolismExtensively metabolized in the liver via CYP2D6 and glucuronidation; active metabolite (4-hydroxynebivolol) contributes to effects.
Half-Life10-12 hours in extensive metabolizers; 19-32 hours in poor metabolizers.
ExcretionPrimarily renal (38% as metabolites, <1% unchanged) and fecal (44%).
Bioavailability12-96% depending on CYP2D6 phenotype; extensive first-pass metabolism.
Onset of Action1-2 hours
Peak Plasma Time1.5-4 hours
Duration of Action24 hours

How It Works

Selective beta-1 adrenergic receptor antagonist; also has nitric oxide-mediated vasodilatory effects.

Mechanism Steps

1Selectively blocks beta-1 adrenergic receptors in cardiac tissue
2Reduces sympathetic nervous system activity
3Decreases heart rate and myocardial contractility

๐Ÿ’ก How to Take cardiolol 5mg tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of cardiolol 5mg tablet

โœ… Common Side Effects

  • Headache
  • Dizziness
  • Fatigue
  • Nausea
  • Bradycardia
  • Edema

๐Ÿšจ Serious Side Effects

  • Heart block
  • Bronchospasm
  • Severe hypotension
  • Heart failure exacerbation

โš ๏ธ Rare Side Effects

  • Thrombocytopenia
  • Anaphylaxis
  • Stevens-Johnson syndrome
  • Hepatotoxicity

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Paroxetine Major Increased nebivolol levels due to CYP2D6 inhibition
Verapamil Major Increased risk of bradycardia and hypotension
Digoxin Moderate Increased risk of bradycardia
Insulin Moderate Masking of hypoglycemia symptoms

๐Ÿšจ Major Interactions

  • CYP2D6 inhibitors (e.g., paroxetine, fluoxetine, quinidine)
  • Other antihypertensives (risk of hypotension)
  • Calcium channel blockers (verapamil, diltiazem)

โšก Moderate Interactions

  • Digoxin
  • Insulin and oral hypoglycemics
  • NSAIDs
  • Beta-blockers

โ„น๏ธ Minor Interactions

  • Cimetidine
  • Rifampin

๐Ÿฝ๏ธ Food Interactions

No significant food interactions.

๐Ÿท Alcohol Interaction

May enhance hypotensive effect; avoid excessive alcohol.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Severe bradycardia, heart block (2nd/3rd degree), cardiogenic shock, decompensated heart failure, sick sinus syndrome, severe hepatic impairment, hypersensitivity.

๐Ÿ“Š Monitoring Parameters

Blood pressure, heart rate, ECG, signs of heart failure, blood glucose in diabetics.

๐Ÿคฑ Lactation Safety

Excreted in breast milk; use with caution.

๐Ÿ’Š Overdose Management

Supportive care; atropine for bradycardia, glucagon for hypotension, beta-agonists for bronchospasm.

โฐ Missed Dose

Take as soon as remembered unless near next dose; skip if close to next dose; do not double.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 28, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for cardiolol 5mg tablet

View All

Alternative brands with exact same active ingredient (Nebivolol (5mg)):

Medical Note: Always consult your doctor before switching medications.

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