caprostat injection - Epsilon Aminocaproic Acid (NA) medicine

Caprostat Injection: Complete Medicine Guide

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🏭 Life Sciences Inc 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 22, 2026
⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Oct 22, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Sudden shortness of breath or chest pain
  • Swelling, pain, or redness in an arm or leg
  • Severe headache with vision changes
  • Decreased urine output or swelling in legs
  • Muscle pain or weakness with dark urine
  • Rash, itching, or swelling of face or throat
  • Unusual bleeding or bruising

If experiencing severe symptoms, call emergency services immediately.

What is caprostat injection used for?

This medicine is an antifibrinolytic injection used to control excessive bleeding by preventing the breakdown of blood clots. It is given by a healthcare professional in a hospital setting.

  • Generic Name: Epsilon Aminocaproic Acid
  • Manufacturer: Life Sciences Inc
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 caprostat injection के बारे में (Hindi Summary)

उपयोग: यह दवा एप्सिलॉन एमिनोकैप्रोइक एसिड (एमिनोकैप्रोइक एसिड) नामक सक्रिय तत्व से बनी है। यह एक एंटीफाइब्रिनोलिटिक दवा है जो रक्त के थक्कों को टूटने से रोकती है। इसका उपयोग अत्यधिक रक्तस्राव को नियंत्रित करने और रोकने के लिए किया जाता है, जैसे सर्जरी के दौरान, दांत निकालने में, हैवी पीरियड्स में, और नाक से खून आने में। यह इंजेक्शन के रूप में दी जाती है और इसे अस्पताल में डॉक्टर या नर्स द्वारा लगाया जाता है। इसे घर पर स्वयं न लगाएं। जिन लोगों को खून के थक्के बनने की समस्या है, उन्हें यह दवा नहीं दी जानी चाहिए।

साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, दस्त, पेट दर्द, सिरदर्द, चक्कर आना और थकान शामिल हैं। गंभीर दुष्प्रभावों में खून के थक्के बनना, मांसपेशियों में कमजोरी, गुर्दे की समस्या, और एलर्जी प्रतिक्रियाएं शामिल हो सकती हैं। यदि आपको सांस लेने में कठिनाई, सूजन, या मांसपेशियों में दर्द हो, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: यह दवा केवल अस्पताल में डॉक्टर की देखरेख में इंजेक्शन द्वारा दी जाती है। इसे स्वयं न लगाएं। अपने डॉक्टर को अपनी सभी चिकित्सीय स्थितियों और दवाओं के बारे में बताएं। यदि आप गर्भवती हैं या स्तनपान करा रही हैं, तो डॉक्टर को बताएं। इलाज के दौरान गुर्दे की कार्यप्रणाली और रक्त के थक्कों की निगरानी की जाएगी। किसी भी असामान्य लक्षण को तुरंत डॉक्टर को बताएं।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 caprostat injection Uses & Benefits

[{"condition":"Excessive bleeding during surgery","description":"Used to reduce bleeding in surgeries such as cardiac, orthopedic, and prostate surgery.","evidence":"Well-established"},{"condition":"Bleeding in hemophilia and other bleeding disorders","description":"Helps control bleeding in patients with hemophilia who are undergoing dental or minor surgical procedures.","evidence":"Well-established"},{"condition":"Heavy menstrual bleeding (menorrhagia)","description":"Can reduce blood loss in women with heavy periods, especially when other treatments are not suitable.","evidence":"Moderate"},{"condition":"Nosebleeds (epistaxis)","description":"Used to control severe or recurrent nosebleeds that do not respond to other measures.","evidence":"Limited"},{"condition":"Subarachnoid hemorrhage","description":"Used to prevent rebleeding after a subarachnoid hemorrhage, although its use is controversial.","evidence":"Limited"}]

Off-label uses: [{"condition":"Prevention of bleeding in patients on thrombolytic therapy","description":"Sometimes used off-label to counteract bleeding caused by clot-dissolving drugs.","evidence":"Limited"},{"condition":"Hereditary angioedema","description":"May be used off-label to prevent attacks of swelling in hereditary angioedema.","evidence":"Limited"}]

Primary treatment for: Excessive bleeding

Also treats: Hemophilia, Menorrhagia, Epistaxis, Subarachnoid hemorrhage

📋 Drug Information

Generic Name(s)Epsilon Aminocaproic Acid
Brand NameCaprostat
ManufacturerLife Sciences Inc
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassBLOOD RELATED
Action ClassAntifibrinolytic
Route of AdministrationIntravenous or intramuscular injection
StorageStore at room temperature (15-30°C). Protect from light. Do not freeze.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Administer this medicine slowly to avoid rapid drop in blood pressure.
2
Monitor kidney function regularly, especially in patients with renal impairment.
3
Watch for signs of blood clots such as swelling, pain, or redness in limbs.
4
Avoid concurrent use with thrombolytic agents unless absolutely necessary.
5
Instruct patients to report any muscle pain or weakness immediately.
6
Use with caution in patients with a history of thromboembolic disease.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Excessive bleeding
This medicine is commonly prescribed for this.
Likely Use
✅
Heavy menstrual bleeding
This medicine can help reduce blood loss.
Likely Use
✅
Nosebleeds
This medicine may be used to control severe nosebleeds.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is administered intravenously or intramuscularly, so absorption is not applicable. It reaches the bloodstream directly.
DistributionIt distributes widely throughout the body, including into tissues and body fluids. It crosses the placenta and is found in breast milk.
Protein BindingNot established from the available information.
MetabolismThis medicine is not significantly metabolized in the liver. It is excreted largely unchanged.
Half-LifeThe elimination half-life is approximately 2 hours.
ExcretionIt is excreted primarily unchanged in the urine via glomerular filtration.
BioavailabilityNot applicable for intravenous administration; bioavailability is 100% for the intravenous route.
Onset of ActionThe onset of action is rapid, within minutes after intravenous administration.
Peak Plasma TimePeak plasma concentration is reached immediately after intravenous injection.
Duration of ActionThe duration of action is approximately 3 to 4 hours after a single dose.

How It Works

This medicine works by blocking the action of plasminogen activators and plasmin, which are enzymes that break down blood clots. By inhibiting these enzymes, it helps stabilize clots and reduce bleeding.

Mechanism Steps

1
Inhibition of plasminogen activation: This medicine binds to plasminogen and prevents its conversion to plasmin by plasminogen activators.
2
Inhibition of plasmin activity: It also directly inhibits the activity of plasmin, the enzyme responsible for breaking down fibrin clots.
3
Stabilization of fibrin clots: By blocking plasmin, the medicine prevents the degradation of fibrin, thereby stabilizing blood clots and reducing bleeding.

💡 How to Take caprostat injection

Strength: This medicine is available as an injection containing epsilon aminocaproic acid (NA). The strength is not specified in the available information.

1This medicine is given by a healthcare professional as an injection.
2It is administered intravenously or intramuscularly.
3Do not self-administer.
4Follow your doctor's instructions regarding monitoring and follow-up.

Dosage Information

Adult DosageThe dose of this medicine is individualized by a qualified clinician based on the indication, patient's age, weight, kidney function, and liver function. For acute bleeding, a typical dose may be 4 to 5 grams given intravenously over the first hour, followed by 1 gram per hour for up to 8 hours or until bleeding is controlled. For oral surgery in hemophilia, a dose of 50 to 100 mg/kg may be given every 6 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may have reduced kidney function and are at higher risk of side effects. Dose should be adjusted based on kidney function. Consult a doctor for individualized dosing.
Renal ImpairmentDose reduction is required in patients with kidney impairment. In severe renal impairment, the medicine should be avoided. Consult a doctor for dose adjustment.
Hepatic ImpairmentNo specific dose adjustment is established for hepatic impairment. Use with caution and monitor liver function.
Maximum Daily DoseThe maximum daily dose is not established from available information. Dosing must be individualized by a clinician.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

No specific food interactions
No restrictions
This medicine is given intravenously and does not interact with food.

⏰ What to Do If You Miss a Dose

📌 You miss a scheduled dose in the hospital
→ Inform your nurse or doctor immediately.
💡 They will administer the dose as soon as possible if appropriate.
📌 You miss an appointment for your injection
→ Contact your doctor to reschedule as soon as possible.
💡 Do not attempt to self-administer.

⚠️ Side Effects of caprostat injection

✅ Common Side Effects

Nausea (Common (5-10%))
Usually resolves on its own. If persistent, inform your doctor.
Vomiting (Common (5-10%))
Stay hydrated. Inform your doctor if vomiting is severe or persistent.
Diarrhea (Common (5-10%))
Drink plenty of fluids. Consult doctor if diarrhea persists.
Headache (Common (5-10%))
Rest and stay hydrated. Consult doctor if headache is severe.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you feel normal.

🚨 Serious Side Effects

Blood clots (thrombosis) (Uncommon (0.1-1%))
Seek immediate medical attention if you experience swelling, pain, redness in limbs, chest pain, or difficulty breathing.
Muscle weakness or breakdown (rhabdomyolysis) (Rare (<0.1%))
Report muscle pain, weakness, or dark urine immediately.
Kidney failure (Rare (<0.1%))
Seek medical attention if you notice decreased urine output or swelling.
Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Call emergency services if you experience rash, itching, swelling of face or throat, or difficulty breathing.

⚠️ Rare Side Effects

Seizures
Seek immediate medical attention.
Irregular heartbeat (arrhythmia)
Report palpitations or fainting to your doctor immediately.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Thrombolytics Major
Anticoagulants Major
Estrogens Moderate
NSAIDs Moderate

🚨 Major Interactions

  • Thrombolytic agents (e.g., streptokinase, alteplase)
  • Anticoagulants (e.g., warfarin, heparin)

⚡ Moderate Interactions

  • Estrogens and oral contraceptives
  • NSAIDs (e.g., ibuprofen, aspirin)

🍷 Alcohol Interaction

Alcohol may increase the risk of dizziness and drowsiness. Avoid alcohol while receiving this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Active intravascular clotting disorder (e.g., deep vein thrombosis, pulmonary embolism)","Disseminated intravascular coagulation (DIC)","Hypersensitivity to epsilon aminocaproic acid","Severe kidney impairment"]

⚠️ Warnings & Precautions

["Use with caution in patients with cardiac, hepatic, or renal disease.","May cause blood clots; monitor for signs of thrombosis.","Avoid in patients with a history of thromboembolic disease.","Not for rapid intravenous injection; administer slowly.","Use with caution in patients with upper urinary tract bleeding."]

🤱 Lactation Safety

This medicine is excreted in breast milk. Consult your doctor before breastfeeding while receiving this medicine.

💊 Overdose Management

Overdose may cause severe nausea, vomiting, hypotension, and thromboembolic events. Treatment is supportive and symptomatic. In case of overdose, seek immediate medical attention.

⏰ Missed Dose

This medicine is given by a healthcare professional in a controlled setting. Missed doses are unlikely. If you miss an appointment for your dose, contact your doctor as soon as possible.

Additional Safety Advice

General Safety

This medicine is given by injection under medical supervision. Do not attempt to self-administer. Inform your doctor if you have a history of blood clots, kidney disease, liver disease, or heart disease. Your doctor will monitor your kidney function, blood counts, and signs of bleeding or clotting during treatment. Avoid activities that increase the risk of injury or bleeding. Do not take any other medicines, including over-the-counter products, without consulting your doctor. If you are pregnant or breastfeeding, tell your doctor before receiving this medicine. Report any unusual symptoms such as muscle pain, weakness, or swelling immediately.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may have reduced kidney function and are at higher risk of side effects. Dose adjustment may be necessary. Close monitoring is recommended.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before receiving this medicine. It should be used during pregnancy only if clearly needed.

🏥 Post-Surgery Considerations

This medicine is often used during surgery to reduce bleeding. After surgery, your doctor will monitor for any signs of bleeding or clotting.

🦷 Dental Procedures

This medicine may be used before dental procedures in patients with bleeding disorders to prevent excessive bleeding. Inform your dentist if you are receiving this medicine.

💚 Lifestyle Tips for Better Results

🏃
Stay well hydrated to support kidney function.
🥗
Avoid activities that increase the risk of injury or bleeding.
😴
Follow a balanced diet to support overall health.
💧
Report any unusual symptoms to your doctor promptly.
🧘
Attend all follow-up appointments for monitoring.

🏋️ Exercise Considerations

Avoid strenuous exercise or activities that may cause injury while receiving this medicine. Consult your doctor before starting any exercise program.

🥗 Diet Recommendations

Drink plenty of fluids
Eat a balanced diet rich in fruits and vegetables
Avoid alcohol

💼 Impact on Daily Work & Life

This medicine may cause dizziness or fatigue. Avoid driving or operating heavy machinery until you know how it affects you. It is usually given in a hospital setting, so work impact is minimal.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. It is given under medical supervision, and the duration of treatment is determined by your condition.

📅 Long-Term Use Effects

Long-term use of this medicine may increase the risk of blood clots and kidney problems. Regular monitoring of kidney function and clotting status is required. Use for extended periods only under strict medical supervision.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Tranexamic acid

Another antifibrinolytic that may be used as an alternative.

Evidence: Well-established
Surgical intervention

In some cases, surgery may be needed to control bleeding.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are known. Consult your doctor before receiving any vaccine while on this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not freeze

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Protect from light

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

This medicine is given in a hospital setting, so travel advice is not applicable. If you are prescribed this medicine for home use, carry it in its original packaging with a copy of your prescription. Store at room temperature and protect from light. Inform security about your medication if traveling by air.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 60-year-old man undergoing prostate surgery
He received this medicine during surgery to reduce bleeding. The surgical team monitored his kidney function and clotting status. He experienced mild nausea but recovered well without any serious complications.
💡 Lesson: Close monitoring during and after administration helps prevent serious side effects.
👤 A 35-year-old woman with heavy menstrual bleeding
She was prescribed this medicine for menorrhagia after other treatments failed. She received it under medical supervision and noticed a significant reduction in bleeding. She was advised to report any leg pain or swelling.
💡 Lesson: This medicine can effectively control heavy bleeding when used under proper medical guidance.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts working within minutes after intravenous administration.

Q: How is this medicine given?

A: It is given as an injection by a healthcare professional, usually intravenously or intramuscularly.

Q: What are the common side effects?

A: Common side effects include nausea, vomiting, diarrhea, headache, and dizziness.

Q: Is this medicine safe during pregnancy?

A: It should be used during pregnancy only if clearly needed and prescribed by a doctor.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine at home?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🛑 Myths vs. Facts

  • Myth: This medicine can be taken at home.
    Fact: This medicine is given by injection only under medical supervision.
  • Myth: This medicine is safe for everyone.
    Fact: It is contraindicated in certain conditions like active blood clotting disorders.

🔄 Alternative Options

Generic Alternatives

  • Epsilon aminocaproic acid injection

📊 Comparison with Similar Medicines

[{"medicine":"Epsilon aminocaproic acid","class":"Antifibrinolytic","route":"Intravenous, intramuscular","half_life":"2 hours"},{"medicine":"Tranexamic acid","class":"Antifibrinolytic","route":"Oral, intravenous","half_life":"2-3 hours"}]

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