candicom 100 capsule - Uses, Price, Side Effects & Substitutes
What is candicom 100 capsule used for?
Alcros 100 Capsule (Itraconazole) is used to treat OPHTHAL. It contains Itraconazole (100mg), which Inhibits fungal cytochrome P450 14ฮฑ-demethylase, blocking ergosterol synthesis . Always consult your doctor before use. Take as prescribed.
- Generic Name: Itraconazole
- Manufacturer: Comed Chemicals Ltd
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ candicom 100 capsule Uses & Benefits
Onychomycosis, dermatophytosis, candidiasis, histoplasmosis, blastomycosis, aspergillosis.
Off-label uses: Coccidioidomycosis, sporotrichosis, chromoblastomycosis, prophylaxis in immunocompromised patients.
๐ Drug Information
| Generic Name(s) | Itraconazole |
| Brand Name | Alcros 100 Capsule |
| Manufacturer | Comed Chemicals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | OPHTHAL |
| Action Class | Fungal ergosterol synthesis inhibitor |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Inhibits fungal cytochrome P450 14ฮฑ-demethylase, blocking ergosterol synthesis and disrupting fungal cell membrane.
Mechanism Steps
๐ก How to Take candicom 100 capsule
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of candicom 100 capsule
โ Common Side Effects
- Nausea
- Abdominal pain
- Diarrhea
- Headache
- Dizziness
- Rash
๐จ Serious Side Effects
- Hepatotoxicity
- Congestive heart failure
- QT prolongation
- Torsades de pointes
- Stevens-Johnson syndrome
โ ๏ธ Rare Side Effects
- Peripheral neuropathy
- Adrenal suppression
- Hypokalemia
- Gynecomastia
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Moderate | Increased INR and bleeding risk |
| Simvastatin | Major | Increased risk of rhabdomyolysis |
| Midazolam | Major | Prolonged sedation and respiratory depression |
๐จ Major Interactions
- CYP3A4 substrates (e.g., midazolam, triazolam)
- HMG-CoA reductase inhibitors (e.g., simvastatin, lovastatin)
- Ergot alkaloids
- Cisapride
- Pimozide
- Quinidine
- Dofetilide
- Lovastatin
- Simvastatin
โก Moderate Interactions
- Warfarin
- Oral hypoglycemics
- Calcium channel blockers
- Digoxin
- Cyclosporine
- Tacrolimus
- Sirolimus
- Carbamazepine
- Phenytoin
- Rifampin
- Isoniazid
- Antacids
- H2 blockers
- Proton pump inhibitors
โน๏ธ Minor Interactions
- Corticosteroids
- Benzodiazepines (e.g., alprazolam)
- Oral contraceptives
๐ฝ๏ธ Food Interactions
Absorption increased with acidic beverages (e.g., cola) and food; avoid grapefruit juice.
๐ท Alcohol Interaction
Avoid alcohol due to potential hepatotoxicity.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to itraconazole or excipients; concomitant use with CYP3A4 substrates with narrow therapeutic index; ventricular dysfunction; pregnancy (category C).
๐ Monitoring Parameters
Liver function tests (ALT, AST), serum potassium, ECG (QT interval), therapeutic drug monitoring if needed.
๐คฑ Lactation Safety
Excreted in breast milk; use with caution.
๐ Overdose Management
Supportive care; no specific antidote; gastric lavage if recent; monitor liver function and ECG.
โฐ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for candicom 100 capsule
View AllAlternative brands with exact same active ingredient (Itraconazole (100mg)):
-
fungizee 100mg capsuleZeelab Pharmacy Pvt Ltd โน20.00 81.7% CHEAPER
-
davaindia itraconazole 100mg capsuleDavaindia Generic Pharmacy โน22.50 79.4% CHEAPER
-
fungiforce -itra 100 capsuleMankind Pharma Ltd โน31.25 71.3% CHEAPER
-
itraks 100mg capsuleAxis Life Science Pvt Ltd โน31.25 71.3% CHEAPER
-
itrason capsuleUnison Pharmaceuticals Pvt Ltd โน32.00 70.6% CHEAPER
-
itrafort 100 capsuleDabur India Ltd โน36.00 67% CHEAPER
-
StayHappi Itraconazole 100mg CapsuleSarvagunaushdhi Pvt Ltd โน36.00 67% CHEAPER
-
candirap 100 capsuleRapross Pharmaceuticals Pvt Ltd โน38.36 64.8% CHEAPER
-
itrasys 100 capsuleSystopic Laboratories Pvt Ltd โน39.00 64.2% CHEAPER
-
itrasys cf 100 capsuleSystopic Laboratories Pvt Ltd โน39.00 64.2% CHEAPER
Medical Note: Always consult your doctor before switching medications.